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Caprin family member 2

 W5QE01_SHEEP            Unreviewed;      1127 AA.
W5QE01;
16-APR-2014, integrated into UniProtKB/TrEMBL.
16-APR-2014, sequence version 1.
23-MAY-2018, entry version 24.
SubName: Full=Caprin family member 2 {ECO:0000313|Ensembl:ENSOARP00000020949};
Name=CAPRIN2 {ECO:0000313|Ensembl:ENSOARP00000020949};
Ovis aries (Sheep).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Caprinae; Ovis.
NCBI_TaxID=9940 {ECO:0000313|Ensembl:ENSOARP00000020949, ECO:0000313|Proteomes:UP000002356};
[1] {ECO:0000313|Ensembl:ENSOARP00000020949, ECO:0000313|Proteomes:UP000002356}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Texel {ECO:0000313|Ensembl:ENSOARP00000020949};
PubMed=20809919; DOI=10.1111/j.1365-2052.2010.02100.x;
Archibald A.L., Cockett N.E., Dalrymple B.P., Faraut T., Kijas J.W.,
Maddox J.F., McEwan J.C., Hutton Oddy V., Raadsma H.W., Wade C.,
Wang J., Wang W., Xun X.;
"The sheep genome reference sequence: a work in progress.";
Anim. Genet. 41:449-453(2010).
[2] {ECO:0000313|Ensembl:ENSOARP00000020949}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2014) to UniProtKB.
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EMBL; AMGL01082483; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AMGL01082484; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Ensembl; ENSOART00000021241; ENSOARP00000020949; ENSOARG00000019503.
GeneTree; ENSGT00760000119052; -.
OMA; YFWDLLE; -.
OrthoDB; EOG091G0UOF; -.
Proteomes; UP000002356; Chromosome 3.
GO; GO:0005813; C:centrosome; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:0043235; C:receptor complex; IEA:Ensembl.
GO; GO:0005102; F:signaling receptor binding; IEA:Ensembl.
GO; GO:0030308; P:negative regulation of cell growth; IEA:Ensembl.
GO; GO:0090263; P:positive regulation of canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0061003; P:positive regulation of dendritic spine morphogenesis; IEA:Ensembl.
GO; GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IEA:Ensembl.
GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
Gene3D; 2.60.120.40; -; 1.
InterPro; IPR001073; C1q_dom.
InterPro; IPR028816; Caprin.
InterPro; IPR022070; Caprin-1_C.
InterPro; IPR008983; Tumour_necrosis_fac-like_dom.
PANTHER; PTHR22922; PTHR22922; 1.
Pfam; PF00386; C1q; 1.
Pfam; PF12287; Caprin-1_C; 1.
PRINTS; PR00007; COMPLEMNTC1Q.
SMART; SM00110; C1Q; 1.
SUPFAM; SSF49842; SSF49842; 1.
PROSITE; PS50871; C1Q; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Complete proteome {ECO:0000313|Proteomes:UP000002356};
Membrane {ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000002356};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 39 61 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 993 1127 C1q. {ECO:0000259|PROSITE:PS50871}.
COILED 130 157 {ECO:0000256|SAM:Coils}.
COILED 178 198 {ECO:0000256|SAM:Coils}.
COILED 440 460 {ECO:0000256|SAM:Coils}.
SEQUENCE 1127 AA; 125884 MW; A7ABD030741AAFA8 CRC64;
NESTAFKTTL SFELTSVEEN FGGRGSRLFR EFKASSHSLV LFLLFFFPFP LSASSVSMVQ
LSSSPFGYQS PSGHSEEGKQ RTMKSAKPQV NHSQHGESQR AMSPLQSALS SAASPSQAYE
TYIDNGLICL KHKIRNIEKK KLKLEDYKDR LKNGEHLNPD QLEAVEKYEE VLHNLEFAKE
LQKTFSGLSQ DLLKAQKKAQ RREHMLKLEA EKKKLRTILQ VQYVLQNLMQ EHVQKDFKGG
LNGAVYLPLK ELDYLIKFSK LTCPERNESL SVEDQMEQSS LYFWDLLEGS EKAVVGTTYK
HMKDLLSKLL NSGYFESIPV PKNAKEKEVS LEEEMLIKSE KKKQLLKTES VKESESLMEL
AQPEIQPQEF LNRRYMTEVD YSSKQDEEQS WEADYARKPN LPKCWDMLTE PDGQEKKQET
FKSWESSVKH QEVSKAAVSL EQRKQEIPKL RSTLQEEQKK QDVSKTKPAP GQWKQEASKS
KAGYIQEEQK KQETLKPWPV QPQKEQEPKK QTPKSWTPSV QSDQDITKSW ASPTCEEQDA
RHPETPKSWE NNVESQKHPL TPQSQISPKS WGVAAASLIP NDQLLPRKFN TEPKDVPKPM
HQPVGSSSTL PKDPVLRKEK LQDLMTQIQG TCNFMQESIL DFDKPSSAIP SSQPPSATPG
SPVASTEQNL SNQSDFLQEP LQAASSPVTC SSNACLVTTD QASSGSETEF MTSETPEAAV
SPSKQPSSLA SPNPPMSKGS EQGFQSPPAS SSSVTINTAP FQAMQTVFNV NAPLPPRKEQ
EIKESPYSPG YNQSFTTAST QTPPQCQLPA IHVEQTVLSQ ETAASFPDGT IQVSNGSLAF
YPAQTNVFPR PSQPFVNSRG SVRGCTRGGR LLTNSYRSPG GYKGFDTYRG PPSISNGNYS
QLQFQAREYP GTPYSQRDNF QQCYKRGGTS GGPRANSRAG WSDSSQVSSP ERDNETFNSG
DSGQGDSRSM TPVDVPVTNP AATILPVHVY PLPQQMRVAF SAARTSNLAP GTLDQPIVFD
LLLNNLGETF DLQLGRFNCP VNGTYVFIFH MLKLAVNVPL YVNLMKNEEV LVSAYANDGA
PDHETASNHA ILQLFQGDQI WLRLHRGAIY GSSWKYSTFS GYLLYQD


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