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Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)

 Q15194_HBV              Unreviewed;       214 AA.
Q15194; Q89499;
01-NOV-1996, integrated into UniProtKB/TrEMBL.
01-NOV-1996, sequence version 1.
12-SEP-2018, entry version 128.
RecName: Full=Capsid protein {ECO:0000256|HAMAP-Rule:MF_04076};
AltName: Full=Core antigen {ECO:0000256|HAMAP-Rule:MF_04076};
AltName: Full=Core protein {ECO:0000256|HAMAP-Rule:MF_04076};
AltName: Full=HBcAg {ECO:0000256|HAMAP-Rule:MF_04076};
AltName: Full=p21.5 {ECO:0000256|HAMAP-Rule:MF_04076};
Name=C {ECO:0000256|HAMAP-Rule:MF_04076,
ECO:0000256|RuleBase:RU361253, ECO:0000313|EMBL:AAP79715.1};
Synonyms=PreC {ECO:0000313|EMBL:CAL29858.1},
preC {ECO:0000313|EMBL:BAN66668.1},
PreC-C {ECO:0000313|EMBL:BAG68743.1},
preC-C {ECO:0000313|EMBL:BAJ15851.1},
PreC/C {ECO:0000313|EMBL:BAF36018.1},
precore {ECO:0000313|EMBL:AAM96930.1},
precore+core {ECO:0000313|EMBL:AAD40206.1};
Hepatitis B virus (HBV).
Viruses; Retro-transcribing viruses; Hepadnaviridae;
Orthohepadnavirus.
NCBI_TaxID=10407 {ECO:0000313|EMBL:AAC31755.1};
NCBI_TaxID=9606; Homo sapiens (Human).
NCBI_TaxID=9598; Pan troglodytes (Chimpanzee).
[1] {ECO:0000313|EMBL:CAA30747.1}
NUCLEOTIDE SEQUENCE.
PubMed=3419915; DOI=10.1093/nar/16.16.8188;
Cheng S., Vogel R., Ye R., Blume M., Lee S., Hung P.;
"The core gene of hepatitis B virus; subtype adw2.";
Nucleic Acids Res. 16:8188-8188(1988).
[2] {ECO:0000313|EMBL:AAC31755.1}
NUCLEOTIDE SEQUENCE.
Meisel H., Jantschak J., Tars K., Prosch S., Pushko P., Pumpens P.;
"Nucleotide sequence of HBV adw variant.";
Submitted (APR-1993) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:CAA96555.1}
NUCLEOTIDE SEQUENCE.
STRAIN=A317 {ECO:0000313|EMBL:CAA96555.1};
Schories M., Schlayer H., Rasenack J.;
"Isolation and characterisation of hepatitis B virus mutants from the
serum of a patient with an immunologically negative HBV infection.";
Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:ADB03200.1, ECO:0000313|Proteomes:UP000167660}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BA3 {ECO:0000313|EMBL:ADB03200.1};
PubMed=9774595;
Mbayed V.A., Lopez J.L., Telenta P.F., Palacios G., Badia I.,
Ferro A., Galoppo C., Campos R.;
"Distribution of hepatitis B virus genotypes in two different
pediatric populations from Argentina.";
J. Clin. Microbiol. 36:3362-3365(1998).
[5] {ECO:0000313|EMBL:AAD40206.1, ECO:0000313|Proteomes:UP000114184, ECO:0000313|Proteomes:UP000168892}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=G2.27246 {ECO:0000313|EMBL:AAD40206.1}, and
G4.27241 {ECO:0000313|EMBL:AAD40214.1};
PubMed=10347133; DOI=10.1002/hep.510290614;
Stuyver L., De Gendt S., Cadranel J.F., Van Geyt C., Van Reybroeck G.,
Dorent R., Gandjbachkh I., Rosenheim M., Charlotte F., Opolon P.,
Huraux J.M., Lunel F.;
"Three cases of severe subfulminant hepatitis in heart-transplanted
patients after nosocomial transmission of a mutant hepatitis B
virus.";
Hepatology 29:1876-1883(1999).
[6] {ECO:0000313|EMBL:AAK97177.1}
NUCLEOTIDE SEQUENCE.
Owiredu W.K.B.A., Kramvis A., Kew M.C.;
Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
[7] {ECO:0000313|EMBL:AAK97177.1, ECO:0000313|Proteomes:UP000155540}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=11468728; DOI=10.1002/jmv.1070;
Owiredu W.K., Kramvis A., Kew M.C.;
"Hepatitis B virus DNA in serum of healthy black African adults
positive for hepatitis B surface antibody alone: possible association
with recombination between genotypes A and D.";
J. Med. Virol. 64:441-454(2001).
[8] {ECO:0000313|EMBL:AAK97198.1, ECO:0000313|Proteomes:UP000097206}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=11596083; DOI=10.1002/jmv.2062.abs;
Owiredu W.K., Kramvis A., Kew M.C.;
"Molecular analysis of hepatitis B virus genomes isolated from black
African patients with fulminant hepatitis B.";
J. Med. Virol. 65:485-492(2001).
[9] {ECO:0000313|EMBL:AAM96930.1}
NUCLEOTIDE SEQUENCE.
Roch G.J., Osiowy C.K.;
"Sequencing of full-length HBV genome insert present in pEco63.";
Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases.
[10] {ECO:0000313|EMBL:AAO12546.1, ECO:0000313|Proteomes:UP000101795, ECO:0000313|Proteomes:UP000180970}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Vaishali C., Acharya S.K., Panda S.K.;
"Cryptic Hepatitis B virus infection: analysis of the complete genomic
sequence of HBV from nine patients with seronegative viral
hepatitis.";
Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
[11] {ECO:0000313|EMBL:AAM96930.1, ECO:0000313|Proteomes:UP000102520}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=14662927; DOI=10.1128/JCM.41.12.5473-5477.2003;
Osiowy C., Giles E.;
"Evaluation of the INNO-LiPA HBV genotyping assay for determination of
hepatitis B virus genotype.";
J. Clin. Microbiol. 41:5473-5477(2003).
[12] {ECO:0000313|EMBL:BAC10530.1, ECO:0000313|Proteomes:UP000101673}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=12436475; DOI=10.1002/jmv.10265;
Sugauchi F., Orito E., Kato H., Suzuki S., Kawakita S., Sakamoto Y.,
Fukushima K., Akiba T., Yoshihara N., Ueda R., Mizokami M.;
"Genotype, serotype, and phylogenetic characterization of the complete
genome sequence of hepatitis B virus isolates from Malawian chronic
carriers of the virus.";
J. Med. Virol. 69:33-40(2003).
[13] {ECO:0000313|Proteomes:UP000147983, ECO:0000313|Proteomes:UP000166261, ECO:0000313|Proteomes:UP000174598}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HBV-TR1 {ECO:0000313|EMBL:BAD08472.1},
HBV-TR2 {ECO:0000313|EMBL:BAD08475.1}, and
HBV-USA2126 {ECO:0000313|EMBL:BAD08466.1};
PubMed=15039524; DOI=10.1099/vir.0.79811-0;
Sugauchi F., Kumada H., Acharya S.A., Shrestha S.M., Gamutan M.T.,
Khan M., Gish R.G., Tanaka Y., Kato T., Orito E., Ueda R.,
Miyakawa Y., Mizokami M.;
"Epidemiological and sequence differences between two subtypes (Ae and
Aa) of hepatitis B virus genotype A.";
J. Gen. Virol. 85:811-820(2004).
[14] {ECO:0000313|Proteomes:UP000095917, ECO:0000313|Proteomes:UP000113756, ECO:0000313|Proteomes:UP000135880}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=0962 {ECO:0000313|EMBL:AAP79715.1},
2 {ECO:0000313|EMBL:AAP79757.1}, 306 {ECO:0000313|EMBL:AAP79771.1},
5283 {ECO:0000313|EMBL:AAP79785.1}, 823 {ECO:0000313|EMBL:AAP79813.1},
and 833 {ECO:0000313|EMBL:AAP79820.1};
PubMed=15105537; DOI=10.1099/vir.0.19749-0;
Kimbi G.C., Kramvis A., Kew M.C.;
"Distinctive sequence characteristics of subgenotype A1 isolates of
hepatitis B virus from South Africa.";
J. Gen. Virol. 85:1211-1220(2004).
[15] {ECO:0000313|Proteomes:UP000116012, ECO:0000313|Proteomes:UP000143721, ECO:0000313|Proteomes:UP000166352}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=1898-98 {ECO:0000313|EMBL:ACF95183.1},
2000-00 {ECO:0000313|EMBL:ACF95169.1},
3782-91 {ECO:0000313|EMBL:ACF95203.1}, and
644-00 {ECO:0000313|EMBL:ACF95190.1};
PubMed=15332270; DOI=10.1002/jmv.20169;
Tallo T., Norder H., Tefanova V., Krispin T., Priimagi L.,
Mukomolov S., Mikhailov M., Magnius L.O.;
"Hepatitis B virus genotype D strains from Estonia share sequence
similarity with strains from Siberia and may specify ayw4.";
J. Med. Virol. 74:221-227(2004).
[16] {ECO:0000313|EMBL:AAT44434.1}
NUCLEOTIDE SEQUENCE.
STRAIN=19T {ECO:0000313|EMBL:AAT44434.1},
31T {ECO:0000313|EMBL:AAT44439.1}, and
32T {ECO:0000313|EMBL:AAT44440.1};
PubMed=15812194; DOI=10.1159/000081748;
Sominskaya I., Mihailova M., Jansons J., Emelyanova V., Folkmane I.,
Smagris E., Dumpis U., Rozentals R., Pumpens P.;
"Hepatitis B and C virus variants in long-term immunosuppressed renal
transplant patients in Latvia.";
Intervirology 48:192-200(2005).
[17] {ECO:0000313|Proteomes:UP000098224, ECO:0000313|Proteomes:UP000116322, ECO:0000313|Proteomes:UP000157482}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=24233 {ECO:0000313|EMBL:AAY25213.1},
380 {ECO:0000313|EMBL:AAY25275.1}, and
9414346 {ECO:0000313|EMBL:AAY25262.1};
PubMed=16033963; DOI=10.1099/vir.0.80972-0;
Hannoun C., Soderstrom A., Norkrans G., Lindh M.;
"Phylogeny of African complete genomes reveals a West African genotype
A subtype of hepatitis B virus and relatedness between Somali and
Asian A1 sequences.";
J. Gen. Virol. 86:2163-2167(2005).
[18] {ECO:0000313|EMBL:AAX07615.1, ECO:0000313|Proteomes:UP000117011}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MTB162 {ECO:0000313|EMBL:AAX07615.1};
Bower W.A., Xia G.-L., Nainan O.V.;
Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
[19] {ECO:0000313|EMBL:BAF36018.1, ECO:0000313|Proteomes:UP000121822, ECO:0000313|Proteomes:UP000172254}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=17006908; DOI=10.1002/hep.21345;
Sugiyama M., Tanaka Y., Kato T., Orito E., Ito K., Acharya S.K.,
Gish R.G., Kramvis A., Shimada T., Izumi N., Kaito M., Miyakawa Y.,
Mizokami M.;
"Influence of hepatitis B virus genotypes on the intra- and
extracellular expression of viral DNA and antigens.";
Hepatology 44:915-924(2006).
[20] {ECO:0000313|EMBL:ABD37008.1, ECO:0000313|Proteomes:UP000138019}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=EI057 {ECO:0000313|EMBL:ABD37008.1};
PubMed=16847957; DOI=10.1002/jmv.20677;
Banerjee A., Kurbanov F., Datta S., Chandra P.K., Tanaka Y.,
Mizokami M., Chakravarty R.;
"Phylogenetic relatedness and genetic diversity of hepatitis B virus
isolates in Eastern India.";
J. Med. Virol. 78:1164-1174(2006).
[21] {ECO:0000313|EMBL:CAL29858.1, ECO:0000313|Proteomes:UP000162724}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Kay A.C.;
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[22] {ECO:0000313|EMBL:CAL69432.1}
NUCLEOTIDE SEQUENCE.
Kay A.C.;
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
[23] {ECO:0000313|EMBL:AAU44346.1, ECO:0000313|Proteomes:UP000168066}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HBV-N10 {ECO:0000313|EMBL:AAU44346.1};
PubMed=17700028; DOI=10.1159/000107044;
Wu T., Chen M., Ou S.H., Cheng T., Zhang J., Xia N.S.;
"Immune response induced by a different combined immunization of HBsAg
vaccine.";
Intervirology 50:336-340(2007).
[24] {ECO:0000313|EMBL:BAF81670.1, ECO:0000313|Proteomes:UP000101998, ECO:0000313|Proteomes:UP000158751}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=17975320; DOI=10.1159/000110651;
Kanada A., Takehara T., Ohkawa K., Tatsumi T., Sakamori R.,
Yamaguchi S., Uemura A., Kohga K., Sasakawa A., Hikita H., Hijioka T.,
Katayama K., Deguchi M., Kagita M., Kanto T., Hiramatsu N.,
Hayashi N.;
"Type B fulminant hepatitis is closely associated with a highly
mutated hepatitis B virus strain.";
Intervirology 50:394-401(2007).
[25] {ECO:0000313|EMBL:CAL29858.1, ECO:0000313|Proteomes:UP000162724}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Margeridon S., Carrouee-Durantel S., Chemin I., Barraud L., Zoulim F.,
Trepo C., Kay A.;
"Rolling circle amplification of residual cccDNA from a chronic
hepatitis B carrier who has seroconverted to anti-HBs.";
Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
[26] {ECO:0000313|EMBL:ABU63578.1, ECO:0000313|Proteomes:UP000131654}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HRO/w4601-2002 {ECO:0000313|EMBL:ABU63578.1};
Buhlmann S., Racek T., Schaefer S., Putzer B.M.;
"Molecular mechanism of p73-mediated regulation of Hepatitis B virus
core promoter/enhancer II.";
Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
[27] {ECO:0000313|EMBL:ADB03200.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BA3 {ECO:0000313|EMBL:ADB03200.1};
Mbayed V.A.;
Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
[28] {ECO:0000313|Proteomes:UP000129703, ECO:0000313|Proteomes:UP000156294, ECO:0000313|Proteomes:UP000164548}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=18606836; DOI=10.1128/AAC.01318-07;
Margeridon S., Carrouee-Durantel S., Chemin I., Barraud L., Zoulim F.,
Trepo C., Kay A.;
"Rolling circle amplification, a powerful tool for genetic and
functional studies of complete hepatitis B virus genomes from low-
level infections and for directly probing covalently closed circular
DNA.";
Antimicrob. Agents Chemother. 52:3068-3073(2008).
[29] {ECO:0000313|Proteomes:UP000116012, ECO:0000313|Proteomes:UP000127894, ECO:0000313|Proteomes:UP000128855}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=1898-98 {ECO:0000313|EMBL:ACF95183.1},
2000-00 {ECO:0000313|EMBL:ACF95169.1},
3782-91 {ECO:0000313|EMBL:ACF95203.1},
4435-97 {ECO:0000313|EMBL:ACF95007.1},
4509-97 {ECO:0000313|EMBL:ACF95049.1},
4512-97 {ECO:0000313|EMBL:ACF95042.1},
4590-97 {ECO:0000313|EMBL:ACF95035.1},
4600-97 {ECO:0000313|EMBL:ACF95028.1},
4620-97 {ECO:0000313|EMBL:ACF95021.1},
4625-97 {ECO:0000313|EMBL:ACF95014.1}, and
644-00 {ECO:0000313|EMBL:ACF95190.1};
PubMed=18632953; DOI=10.1099/vir.0.83660-0;
Tallo T., Tefanova V., Priimagi L., Schmidt J., Katargina O.,
Michailov M., Mukomolov S., Magnius L., Norder H.;
"D2: major subgenotype of hepatitis B virus in Russia and the Baltic
region.";
J. Gen. Virol. 89:1829-1839(2008).
[30] {ECO:0000313|EMBL:ABD37008.1, ECO:0000313|Proteomes:UP000138019}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=EI057 {ECO:0000313|EMBL:ABD37008.1};
PubMed=18952249; DOI=10.1016/j.virol.2008.09.007;
Datta S., Banerjee A., Chandra P.K., Biswas A., Panigrahi R.,
Mahapatra P.K., Panda C.K., Chakrabarti S., Bhattacharya S.K.,
Chakravarty R.;
"Analysis of hepatitis B virus X gene phylogeny, genetic variability
and its impact on pathogenesis: implications in Eastern Indian HBV
carriers.";
Virology 382:190-198(2008).
[31] {ECO:0000313|EMBL:ADB03200.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BA3 {ECO:0000313|EMBL:ADB03200.1};
Pezzano S., Torres C.;
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
[32] {ECO:0000313|Proteomes:UP000119342, ECO:0000313|Proteomes:UP000151241, ECO:0000313|Proteomes:UP000154513}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=JPN_CH1 {ECO:0000313|EMBL:BAG68743.1},
JPN_CH2 {ECO:0000313|EMBL:BAG68747.1},
JPN_CH3 {ECO:0000313|EMBL:BAG68751.1}, and
JPN_CH6 {ECO:0000313|EMBL:BAG68762.1};
PubMed=19297602; DOI=10.1128/JCM.02081-08;
Matsuura K., Tanaka Y., Hige S., Yamada G., Murawaki Y., Komatsu M.,
Kuramitsu T., Kawata S., Tanaka E., Izumi N., Okuse C., Kakumu S.,
Okanoue T., Hino K., Hiasa Y., Sata M., Maeshiro T., Sugauchi F.,
Nojiri S., Joh T., Miyakawa Y., Mizokami M.;
"Distribution of hepatitis B virus genotypes among patients with
chronic infection in Japan shifting toward an increase of genotype
A.";
J. Clin. Microbiol. 47:1476-1483(2009).
[33] {ECO:0000313|Proteomes:UP000097734, ECO:0000313|Proteomes:UP000098381, ECO:0000313|Proteomes:UP000099814}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C102 {ECO:0000313|EMBL:ACJ66174.1},
C109 {ECO:0000313|EMBL:ACJ66160.1},
C110 {ECO:0000313|EMBL:ACJ66153.1},
C122 {ECO:0000313|EMBL:ACJ66139.1},
C126 {ECO:0000313|EMBL:ACJ66071.1},
C151 {ECO:0000313|EMBL:ACJ66195.1},
C152 {ECO:0000313|EMBL:ACJ66201.1},
C153 {ECO:0000313|EMBL:ACJ66146.1},
C155 {ECO:0000313|EMBL:ACJ66181.1}, C35 {ECO:0000313|EMBL:ACJ66251.1},
C39 {ECO:0000313|EMBL:ACJ66244.1}, C40 {ECO:0000313|EMBL:ACJ66119.1},
C42 {ECO:0000313|EMBL:ACJ66237.1}, C55 {ECO:0000313|EMBL:ACJ66230.1},
C62 {ECO:0000313|EMBL:ACJ66216.1}, C64 {ECO:0000313|EMBL:ACJ66209.1},
C67 {ECO:0000313|EMBL:ACJ66092.1}, C69 {ECO:0000313|EMBL:ACJ66085.1},
C85 {ECO:0000313|EMBL:ACJ66188.1}, C96 {ECO:0000313|EMBL:ACJ66078.1},
P01 {ECO:0000313|EMBL:ACJ66057.1}, P03 {ECO:0000313|EMBL:ACJ65973.1},
P06 {ECO:0000313|EMBL:ACJ66043.1}, P07 {ECO:0000313|EMBL:ACJ65966.1},
P08 {ECO:0000313|EMBL:ACJ66008.1}, P09 {ECO:0000313|EMBL:ACJ66015.1},
P13 {ECO:0000313|EMBL:ACJ65980.1}, P15 {ECO:0000313|EMBL:ACJ66022.1},
P16 {ECO:0000313|EMBL:ACJ66029.1}, P17 {ECO:0000313|EMBL:ACJ65987.1},
P20 {ECO:0000313|EMBL:ACJ65959.1}, P21 {ECO:0000313|EMBL:ACJ66001.1},
P22 {ECO:0000313|EMBL:ACJ66036.1}, P24 {ECO:0000313|EMBL:ACJ65952.1},
P25 {ECO:0000313|EMBL:ACJ66050.1}, P26 {ECO:0000313|EMBL:ACJ65938.1},
P27 {ECO:0000313|EMBL:ACJ65931.1}, P28 {ECO:0000313|EMBL:ACJ65917.1},
P29 {ECO:0000313|EMBL:ACJ65910.1}, P30 {ECO:0000313|EMBL:ACJ65903.1},
P31 {ECO:0000313|EMBL:ACJ65924.1}, P32 {ECO:0000313|EMBL:ACJ65875.1},
P37 {ECO:0000313|EMBL:ACJ65868.1}, P38 {ECO:0000313|EMBL:ACJ65896.1},
P39 {ECO:0000313|EMBL:ACJ65889.1}, P40 {ECO:0000313|EMBL:ACJ65882.1},
P42 {ECO:0000313|EMBL:ACJ65861.1}, P43 {ECO:0000313|EMBL:ACJ66064.1},
and P44 {ECO:0000313|EMBL:ACJ65854.1};
PubMed=19615936; DOI=10.1016/j.jcv.2009.06.015;
Pourkarim M.R., Verbeeck J., Rahman M., Amini-Bavil-Olyaee S.,
Forier A.M., Lemey P., Maes P., Van Ranst M.;
"Phylogenetic analysis of hepatitis B virus full-length genomes
reveals evidence for a large nosocomial outbreak in Belgium.";
J. Clin. Virol. 46:61-68(2009).
[34] {ECO:0000313|Proteomes:UP000103056, ECO:0000313|Proteomes:UP000124635, ECO:0000313|Proteomes:UP000139693}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=06-23 {ECO:0000313|EMBL:BAJ15851.1},
06-27 {ECO:0000313|EMBL:BAJ15855.1}, and
06-51 {ECO:0000313|EMBL:BAJ15863.1};
Kojima Y., Kawahata T., Mori H.;
"genotypes of hepatitis B virus in patients with HIV infection.";
Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
[35] {ECO:0000313|EMBL:ACV49872.1, ECO:0000313|Proteomes:UP000140356}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=GTA_CT {ECO:0000313|EMBL:ACV49872.1};
Midilli K., Kuskucu M., Ergin S., Celebi E., Yarimcam F., Yilmaz G.,
Altas K.;
"First description of HBV Genotype A in Turkey.";
Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
[36] {ECO:0000313|EMBL:ACO89755.1, ECO:0000313|Proteomes:UP000131214}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=H71 {ECO:0000313|EMBL:ACO89755.1};
PubMed=20087936; DOI=10.1002/jmv.21726;
Pourkarim M.R., Amini-Bavil-Olyaee S., Verbeeck J., Lemey P.,
Zeller M., Rahman M., Maes P., Nevens F., Van Ranst M.;
"Molecular evolutionary analysis and mutational pattern of full-length
genomes of hepatitis B virus isolated from Belgian patients with
different clinical manifestations.";
J. Med. Virol. 82:379-389(2010).
[37] {ECO:0000313|EMBL:ACX69327.1, ECO:0000313|Proteomes:UP000145853, ECO:0000313|Proteomes:UP000148058}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=P130 {ECO:0000313|EMBL:ACX69604.1}, and
P3 {ECO:0000313|EMBL:ACX69327.1};
PubMed=19780948; DOI=10.1111/j.1365-2893.2009.01192.x;
Polish Blood Transfusion Centres Viral Study Group;
Grabarczyk P., Garmiri P., Liszewski G., Doucet D., Sulkowska E.,
Brojer E., Allain J.P.;
"Molecular and serological characterization of hepatitis B virus
genotype A and D infected blood donors in Poland.";
J. Viral Hepat. 17:444-452(2010).
[38] {ECO:0000313|Proteomes:UP000124849, ECO:0000313|Proteomes:UP000127137, ECO:0000313|Proteomes:UP000128971}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BV-10 {ECO:0000313|EMBL:ADX42365.1},
BV-108 {ECO:0000313|EMBL:ADX42341.1},
BV-189 {ECO:0000313|EMBL:ADX42426.1},
BV-25 {ECO:0000313|EMBL:ADX42372.1},
BV-35 {ECO:0000313|EMBL:ADX42379.1},
BV-66 {ECO:0000313|EMBL:ADX42328.1},
BV-78 {ECO:0000313|EMBL:ADX42392.1}, and
BV-90 {ECO:0000313|EMBL:ADX42399.1};
Pourkarim M.R., Amini-Bavil-Olyaee S., Lemey P., Zeller M.,
Wambacq J., Maes P., Van Ranst M.;
"Molecular Characterization of HBV strains circulating in HIV/HBV co-
infected patients in Belgium: overt and occult infection.";
Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
[39] {ECO:0000313|EMBL:BAI81984.1, ECO:0000313|Proteomes:UP000147734}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Komatsu H., Inui A., Sogo T., Fujisawa T.;
"Sequencing of hepatitis B virus complete genome isolated from a
child, father, and grandfather.";
Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
[40] {ECO:0000313|EMBL:BAL60911.1}
NUCLEOTIDE SEQUENCE.
STRAIN=No10 {ECO:0000313|EMBL:BAL60960.1},
No11 {ECO:0000313|EMBL:BAL60967.1},
No14 {ECO:0000313|EMBL:BAL60974.1},
No16 {ECO:0000313|EMBL:BAL60988.1},
No19 {ECO:0000313|EMBL:BAL61002.1}, No2 {ECO:0000313|EMBL:BAL60911.1},
No22 {ECO:0000313|EMBL:BAL61015.1},
No23 {ECO:0000313|EMBL:BAL61022.1},
No25 {ECO:0000313|EMBL:BAL61029.1},
No28 {ECO:0000313|EMBL:BAL61036.1},
No29 {ECO:0000313|EMBL:BAL61043.1}, No3 {ECO:0000313|EMBL:BAL60918.1},
No31 {ECO:0000313|EMBL:BAL61050.1},
No32 {ECO:0000313|EMBL:BAL61057.1},
No37 {ECO:0000313|EMBL:BAL61077.1}, No7 {ECO:0000313|EMBL:BAL60939.1},
and No8 {ECO:0000313|EMBL:BAL60946.1};
Fujisaki S., Yokomaku Y., Shiino T., Koibuchi T., Hattori J., Ibe S.,
Iwatani Y., Iwamoto A., Shirasaka T., Hamaguchi M., Sugiura W.;
"Outbreak of Infections by Hepatitis B Virus Genotype A and
Transmission of Genetic Drug Resistance in Patients Coinfected with
HIV-1 in Japan.";
J. Clin. Microbiol. 49:1017-1024(2011).
[41] {ECO:0000313|Proteomes:UP000100713, ECO:0000313|Proteomes:UP000118571, ECO:0000313|Proteomes:UP000119150}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=21248087; DOI=10.1128/JCM.02149-10;
Fujisaki S., Yokomaku Y., Shiino T., Koibuchi T., Hattori J., Ibe S.,
Iwatani Y., Iwamoto A., Shirasaka T., Hamaguchi M., Sugiura W.;
"Outbreak of infections by hepatitis B virus genotype A and
transmission of genetic drug resistance in patients coinfected with
HIV-1 in Japan.";
J. Clin. Microbiol. 49:1017-1024(2011).
[42] {ECO:0000313|EMBL:AFJ79459.1, ECO:0000313|Proteomes:UP000103322}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Srb 176 {ECO:0000313|EMBL:AFJ79459.1};
Lazarevic I., Cupic M., Delic D., Stojkovic Svirtlih N., Simonovic J.,
Banko A., Jovanovic T.;
"Complete genome sequences and phylogenetic analysis of hepatitis B
virus isolates from Serbia.";
Arch. Biol. Sci. 64:1319-1326(2012).
[43] {ECO:0000313|Proteomes:UP000101878, ECO:0000313|Proteomes:UP000109895, ECO:0000313|Proteomes:UP000149420}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=21981386; DOI=10.1111/j.1537-2995.2011.03355.x;
Vermeulen M., Dickens C., Lelie N., Walker E., Coleman C., Keyter M.,
Reddy R., Crookes R., Kramvis A.;
"Hepatitis B virus transmission by blood transfusion during 4 years of
individual-donation nucleic acid testing in South Africa: estimated
and observed window period risk.";
Transfusion 52:880-892(2012).
[44] {ECO:0000313|EMBL:BAL60911.1}
NUCLEOTIDE SEQUENCE.
STRAIN=No10 {ECO:0000313|EMBL:BAL60960.1},
No11 {ECO:0000313|EMBL:BAL60967.1},
No14 {ECO:0000313|EMBL:BAL60974.1},
No16 {ECO:0000313|EMBL:BAL60988.1},
No19 {ECO:0000313|EMBL:BAL61002.1}, No2 {ECO:0000313|EMBL:BAL60911.1},
No22 {ECO:0000313|EMBL:BAL61015.1},
No23 {ECO:0000313|EMBL:BAL61022.1},
No25 {ECO:0000313|EMBL:BAL61029.1},
No28 {ECO:0000313|EMBL:BAL61036.1},
No29 {ECO:0000313|EMBL:BAL61043.1}, No3 {ECO:0000313|EMBL:BAL60918.1},
No31 {ECO:0000313|EMBL:BAL61050.1},
No32 {ECO:0000313|EMBL:BAL61057.1},
No37 {ECO:0000313|EMBL:BAL61077.1}, No7 {ECO:0000313|EMBL:BAL60939.1},
and No8 {ECO:0000313|EMBL:BAL60946.1};
Fujisaki S., Yokomaku Y., Hattori J., Ibe S., Iwatani Y.,
Hamaguchi M., Sugiura W.;
Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
[45] {ECO:0000313|EMBL:AFQ36940.1, ECO:0000313|Proteomes:UP000174580}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=11-10165 {ECO:0000313|EMBL:AFQ36940.1};
Silamikelis I., Legzdina D.;
"Phylogenetic analysis of representative Hepatitis B virus full
genomes from Latvia.";
Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
[46] {ECO:0000313|Proteomes:UP000101147, ECO:0000313|Proteomes:UP000157412, ECO:0000313|Proteomes:UP000159513}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HB10-0707 {ECO:0000313|EMBL:BAN66668.1},
HB10-0708 {ECO:0000313|EMBL:BAN66672.1},
HB12-0925 {ECO:0000313|EMBL:BAN66676.1}, and
HB12-0929 {ECO:0000313|EMBL:BAN66680.1};
Aikawa T., Tsuda F., Ueno C., Mamiya T., Sugiyama H., Soeda A.,
Ikezawa K., Nagashima S., Takahashi M., Okamoto H.;
"Transmission of genotype A (A2) hepatitis B virus from patients who
developed acute hepatitis B to their sexual partners, via interspousal
or homosexual infection.";
Kanzo 54:373-380(2013).
[47] {ECO:0000313|EMBL:AGN92535.1}
NUCLEOTIDE SEQUENCE.
STRAIN=AH2 {ECO:0000313|EMBL:AGN92535.1},
AH25 {ECO:0000313|EMBL:AGN92569.1}, AH3 {ECO:0000313|EMBL:AGN92537.1},
and AH32 {ECO:0000313|EMBL:AGN92579.1};
Huang N.-L., Huang M.-D., Chen T.-L.L., Huang A.H.;
Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
[48] {ECO:0000313|Proteomes:UP000115590, ECO:0000313|Proteomes:UP000117236, ECO:0000313|Proteomes:UP000139217}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=3358v1 {ECO:0000313|EMBL:AHM26212.1},
3358v2 {ECO:0000313|EMBL:AHM26219.1}, and
3358v3 {ECO:0000313|EMBL:AHM26226.1};
Le Clercq L.S.III., Bowyer S.M., Mayaphi S.H.;
"Molecular characterization of full genome Hepatitis B virus (HBV)
sequences from an urban hospital cohort in Pretoria, South Africa.";
Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
[49] {ECO:0000313|EMBL:AIZ95353.1, ECO:0000313|Proteomes:UP000123557, ECO:0000313|Proteomes:UP000142886}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=A1_Wild_SA {ECO:0000313|EMBL:AIZ95353.1}, and
A2_WT_BEL {ECO:0000313|EMBL:AIZ95360.1};
PubMed=24681050; DOI=10.1016/j.jviromet.2014.03.015;
Bhoola N.H., Reumann K., Kew M.C., Will H., Kramvis A.;
"Construction of replication competent plasmids of hepatitis B virus
subgenotypes A1, A2 and D3 with authentic endogenous promoters.";
J. Virol. Methods 203:54-64(2014).
[50] {ECO:0000313|Proteomes:UP000100868, ECO:0000313|Proteomes:UP000102483, ECO:0000313|Proteomes:UP000124116}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=HB13-0302 {ECO:0000313|EMBL:BAP81751.1},
HB13-0666 {ECO:0000313|EMBL:BAP81755.1},
HB13-1205 {ECO:0000313|EMBL:BAP81747.1}, and
HB14-0383 {ECO:0000313|EMBL:BAP81771.1};
Aikawa T., Sugiyama H., Soeda A., Ikezawa K., Sato T., Tsuda F.,
Ueno C., Okamoto H.;
"Changing trends of genotypic distribution of hepatitis B virus in
Mito, Japan (2001-2013).";
Kanzo 55:626-629(2014).
[51] {ECO:0000313|EMBL:AIJ49843.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Ag04 {ECO:0000313|EMBL:AIJ49843.1},
Ag11 {ECO:0000313|EMBL:AIJ49892.1},
Ag25 {ECO:0000313|EMBL:AIJ49983.1},
Ag27 {ECO:0000313|EMBL:AIJ49996.1},
Ag31 {ECO:0000313|EMBL:AIJ50024.1},
Ag55 {ECO:0000313|EMBL:AIJ50177.1},
Ag56 {ECO:0000313|EMBL:AIJ50184.1},
Ag57 {ECO:0000313|EMBL:AIJ50191.1},
Ag62 {ECO:0000313|EMBL:AIJ50198.1}, and
Ag63 {ECO:0000313|EMBL:AIJ50205.1};
Rodrigo M.B.;
"Analysis of the molecular evolution of Hepatitis B genotypes in acute
infections.";
Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
[52] {ECO:0000313|EMBL:ALI58685.1, ECO:0000313|Proteomes:UP000101771, ECO:0000313|Proteomes:UP000149021}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=GS-1 {ECO:0000313|EMBL:ALI58685.1}, and
GS-3 {ECO:0000313|EMBL:ALI58698.1};
PubMed=26342803; DOI=10.1016/j.jcv.2015.08.010;
Mina T., Amini-Bavil-Olyaee S., Dekervel J., Verslype C., Nevens F.,
Maes P., Tacke F., Van Ranst M., Pourkarim M.R.;
"A rare case of HBV genotype fluctuation (shifting and reversion)
after liver transplantation.";
J. Clin. Virol. 71:93-97(2015).
[53] {ECO:0000313|EMBL:AIW67670.1, ECO:0000313|Proteomes:UP000148039, ECO:0000313|Proteomes:UP000163148}
NUCLEOTIDE SEQUENCE.
STRAIN=Cuba14 {ECO:0000313|EMBL:AIW68011.1},
Cuba14a {ECO:0000313|EMBL:AIW67670.1},
Cuba20a {ECO:0000313|EMBL:AIW67685.1},
Cuba34a {ECO:0000313|EMBL:AIW67713.1},
Cuba38a {ECO:0000313|EMBL:AIW67724.1},
Cuba45a {ECO:0000313|EMBL:AIW67746.1},
Cuba56 {ECO:0000313|EMBL:AIW68028.1},
Cuba56a {ECO:0000313|EMBL:AIW67764.1},
Cuba59a {ECO:0000313|EMBL:AIW67771.1},
Cuba60a {ECO:0000313|EMBL:AIW67775.1},
Cuba61a {ECO:0000313|EMBL:AIW67778.1},
Cuba66a {ECO:0000313|EMBL:AIW67787.1},
Cuba69a {ECO:0000313|EMBL:AIW67797.1},
Cuba71a {ECO:0000313|EMBL:AIW67801.1},
Cuba72a {ECO:0000313|EMBL:AIW67805.1},
Cuba75a {ECO:0000313|EMBL:AIW67811.1},
Cuba82a {ECO:0000313|EMBL:AIW67825.1}, and
Cuba85a {ECO:0000313|EMBL:AIW67834.1};
PubMed=25742179;
Loureiro C.L., Aguilar J.C., Aguiar J., Muzio V., Penton E.,
Garcia D., Guillen G., Pujol F.H.;
"HBV genotypic variability in cuba.";
PLoS ONE 10:E0118959-E0118959(2015).
[54] {ECO:0000313|Proteomes:UP000100674, ECO:0000313|Proteomes:UP000101428, ECO:0000313|Proteomes:UP000104429}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Ag04 {ECO:0000313|EMBL:AIJ49843.1},
Ag11 {ECO:0000313|EMBL:AIJ49892.1},
Ag25 {ECO:0000313|EMBL:AIJ49983.1},
Ag27 {ECO:0000313|EMBL:AIJ49996.1},
Ag31 {ECO:0000313|EMBL:AIJ50024.1},
Ag55 {ECO:0000313|EMBL:AIJ50177.1},
Ag56 {ECO:0000313|EMBL:AIJ50184.1},
Ag57 {ECO:0000313|EMBL:AIJ50191.1},
Ag62 {ECO:0000313|EMBL:AIJ50198.1}, and
Ag63 {ECO:0000313|EMBL:AIJ50205.1};
PubMed=25822666;
Gonzalez Lopez Ledesma M.M., Mojsiejczuk L.N., Rodrigo B., Sevic I.,
Mammana L., Galdame O., Gadano A., Fainboim H., Campos R.,
Flichman D.;
"Hepatitis B Virus Genotype Distribution and Genotype-Specific
BCP/preCore Substitutions in Acute and Chronic Infections in
Argentina.";
PLoS ONE 10:E0121436-E0121436(2015).
[55] {ECO:0000313|Proteomes:UP000102873, ECO:0000313|Proteomes:UP000104884, ECO:0000313|Proteomes:UP000107699}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=3106_HIV {ECO:0000313|EMBL:AKZ16515.1},
GP13-1943 {ECO:0000313|EMBL:AKZ16510.1},
GP13-378 {ECO:0000313|EMBL:AKZ16520.1},
PA-01-1162 {ECO:0000313|EMBL:AKZ16465.1},
PA-01-1771 {ECO:0000313|EMBL:AKZ16480.1}, and
PA-01-1897 {ECO:0000313|EMBL:AKZ16460.1};
PubMed=26230260;
Martinez A.A., Zaldivar Y., Arteaga G., de Castillo Z., Ortiz A.,
Mendoza Y., Castillero O., Castillo J.A., Cristina J., Pascale J.M.;
"Phylogenetic Analysis of Hepatitis B Virus Genotypes Circulating in
Different Risk Groups of Panama, Evidence of the Introduction of
Genotype A2 in the Country.";
PLoS ONE 10:E0134850-E0134850(2015).
[56] {ECO:0000313|EMBL:AKZ16460.1}
NUCLEOTIDE SEQUENCE.
STRAIN=3106_HIV {ECO:0000313|EMBL:AKZ16515.1},
GP13-1943 {ECO:0000313|EMBL:AKZ16510.1},
GP13-378 {ECO:0000313|EMBL:AKZ16520.1},
PA-01-1162 {ECO:0000313|EMBL:AKZ16465.1},
PA-01-1771 {ECO:0000313|EMBL:AKZ16480.1}, and
PA-01-1897 {ECO:0000313|EMBL:AKZ16460.1};
Zhang J.;
"Establishment of an Ehrlichia FRET-qPCR to investigate the prevalence
of ehrlichiosis in ruminants from five Caribbean islands.";
Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
[57] {ECO:0000313|EMBL:ALS87636.1, ECO:0000313|Proteomes:UP000097177, ECO:0000313|Proteomes:UP000098849}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ZADGM265 {ECO:0000313|EMBL:ALS87636.1}, and
ZADGM285 {ECO:0000313|EMBL:ALS87640.1};
Gededzha M.P., Muzeze M., Burnett R.J., Amponsah-Dacosta E.,
Mphahlele J., Selabe S.G.;
"Complete genome analysis of hepatitis B virus in human
immunodeficiency virus infected and uninfected South Africans.";
Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
[58] {ECO:0000313|Proteomes:UP000097454, ECO:0000313|Proteomes:UP000158149, ECO:0000313|Proteomes:UP000169555}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KSM564 {ECO:0000313|EMBL:ALG02676.1},
KSM571 {ECO:0000313|EMBL:ALG02608.1}, and
NRB517 {ECO:0000313|EMBL:ALG02601.1};
PubMed=26932656; DOI=10.1186/s12879-016-1409-2;
Ochwoto M., Kimotho J.H., Oyugi J., Okoth F., Kioko H., Mining S.,
Budambula N.L., Giles E., Andonov A., Songok E., Osiowy C.;
"Hepatitis B infection is highly prevalent among patients presenting
with jaundice in Kenya.";
BMC Infect. Dis. 16:101-101(2016).
[59] {ECO:0000313|Proteomes:UP000099050, ECO:0000313|Proteomes:UP000101357, ECO:0000313|Proteomes:UP000109884}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=27245151; DOI=10.1016/j.meegid.2016.05.035;
Amponsah-Dacosta E., Rakgole N.J., Gededzha M.P., Lukhwareni A.,
Blackard J.T., Selabe S.G., Mphahlele J.;
"Evidence of susceptibility to lamivudine-based HAART and genetic
stability of hepatitis B virus (HBV) in HIV co-infected patients: A
South African longitudinal HBV whole genome study.";
Infect. Genet. Evol. 43:232-238(2016).
[60] {ECO:0000313|EMBL:ANH21981.1}
NUCLEOTIDE SEQUENCE.
STRAIN=ZADGM1163Baseline {ECO:0000313|EMBL:ANH22003.1},
ZADGM1486Baseline {ECO:0000313|EMBL:ANH21981.1},
ZADGM4643F1 {ECO:0000313|EMBL:ANH22016.1},
ZADGM4643F2 {ECO:0000313|EMBL:ANH22023.1},
ZADGM4643F3 {ECO:0000313|EMBL:ANH22030.1}, and
ZADGM8787F2 {ECO:0000313|EMBL:ANH21996.1};
Amponsah-Dacosta E., Rakgole N.J., Gededzha M.P., Lukhwareni A.,
Blackard J.T., Selabe S.G., Mphahlele J.;
"Evidence of Susceptibility to Lamivudine-Based HAART and Genetic
Stability of Hepatitis B Virus (HBV) in HIV Co-infected Patients: A
South African Longitudinal HBV Whole Genome Study.";
Infect. Genet. Evol. 0:0-0(2016).
[61] {ECO:0000313|EMBL:ANZ72792.1, ECO:0000313|Proteomes:UP000165795}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Zi14_091 {ECO:0000313|EMBL:ANZ72792.1};
PubMed=27458715;
Baudi I., Iijima S., Chin'ombe N., Mtapuri-Zinyowera S., Murakami S.,
Isogawa M., Hachiya A., Iwatani Y., Tanaka Y.;
"Molecular epidemiology of co-infection with hepatitis B virus and
human immunodeficiency virus (HIV) among adult patients in Harare,
Zimbabwe.";
J. Med. Virol. 0:0-0(2016).
[62] {ECO:0000313|Proteomes:UP000139412, ECO:0000313|Proteomes:UP000154311, ECO:0000313|Proteomes:UP000173368}
NUCLEOTIDE SEQUENCE.
STRAIN=AH2 {ECO:0000313|EMBL:AGN92535.1},
AH25 {ECO:0000313|EMBL:AGN92569.1}, AH3 {ECO:0000313|EMBL:AGN92537.1},
and AH32 {ECO:0000313|EMBL:AGN92579.1};
PubMed=27280441;
Lin S.Y., Toyoda H., Kumada T., Liu H.F.;
"Molecular Evolution and Phylodynamics of Acute Hepatitis B Virus in
Japan.";
PLoS ONE 11:E0157103-E0157103(2016).
[63] {ECO:0000313|EMBL:AIZ50124.1, ECO:0000313|Proteomes:UP000114457}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=A1-SA {ECO:0000313|EMBL:AIZ50124.1};
PubMed=27002608; DOI=10.1007/s11262-016-1307-0;
Cai Q., Zhu H., Zhang Y., Li X., Zhang Z.;
"Hepatitis B virus genotype A: design of reference sequences for sub-
genotypes.";
Virus Genes 52:325-333(2016).
[64] {ECO:0000313|EMBL:APD28360.1}
NUCLEOTIDE SEQUENCE.
STRAIN=20160922 {ECO:0000313|EMBL:APD28360.1};
Jenkins A., Minhas R., Morris C., Berry N.;
"Complete Genome Sequence of the WHO International Standard for HBV
RNA determined by Sanger Sequencing.";
Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Encapsidates hepatitis delta genome. {ECO:0000256|HAMAP-
Rule:MF_04076}.
-!- FUNCTION: May regulate immune response to the intracellular capsid
in acting as a T-cell tolerogen, by having an immunoregulatory
effect which prevents destruction of infected cells by cytotoxic
T-cells. {ECO:0000256|RuleBase:RU361253}.
-!- FUNCTION: Self assembles to form an icosahedral capsid. Most
capsid appear to be large particles with a icosahedral symmetry of
T=4 and consist of 240 copies of capsid protein, though a fraction
forms smaller T=3 particles consisting of 180 capsid proteins.
Entering capsid are transported along microtubules to the nucleus.
Phosphorylation of the capsid is thought to induce exposure of
nuclear localization signal in the C-terminal portion of the
capsid protein that allows binding to the nuclear pore complex via
the importin (karyopherin-) alpha and beta. Capsids are imported
in intact form through the nuclear pore into the nuclear basket,
where it probably binds NUP153. Only capsids that contain the
mature viral genome can release the viral DNA and capsid protein
into the nucleoplasm. Immature capsids get stucked in the basket.
Capsids encapsulate the pre-genomic RNA and the P protein. Pre-
genomic RNA is reverse transcribed into DNA while the capsid is
still in the cytoplasm. The capsid can then either be directed to
the nucleus, providing more genome for transcription, or bud
through the endoplasmic reticulum to provide new virions.
{ECO:0000256|HAMAP-Rule:MF_04076}.
-!- SUBUNIT: Homodimerizes, then multimerizes. Interacts with cytosol
exposed regions of viral L glycoprotein present in the reticulum-
to-Golgi compartment. Interacts with human FLNB. Phosphorylated
form interacts with host importin alpha; this interaction depends
on the exposure of the NLS, which itself depends upon genome
maturation and/or phosphorylation of the capsid protein. Interacts
with host NUP153. {ECO:0000256|HAMAP-Rule:MF_04076}.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU361253}.
Virion {ECO:0000256|HAMAP-Rule:MF_04076}. Host cytoplasm
{ECO:0000256|HAMAP-Rule:MF_04076}.
-!- PTM: Cleaved by host furin. {ECO:0000256|RuleBase:RU361253}.
-!- PTM: Phosphorylated by host SRPK1, SRPK2, and maybe protein kinase
C or GAPDH. Phosphorylation is critical for pregenomic RNA
packaging. Protein kinase C phosphorylation is stimulated by HBx
protein and may play a role in transport of the viral genome to
the nucleus at the late step during viral replication cycle.
{ECO:0000256|HAMAP-Rule:MF_04076}.
-!- SIMILARITY: Belongs to the orthohepadnavirus core antigen family.
{ECO:0000256|HAMAP-Rule:MF_04076}.
-!- SIMILARITY: Belongs to the orthohepadnavirus precore antigen
family. {ECO:0000256|RuleBase:RU361253}.
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EMBL; L13994; AAC31755.1; -; mRNA.
EMBL; AF090839; AAD40206.1; -; Genomic_DNA.
EMBL; AF090841; AAD40214.1; -; Genomic_DNA.
EMBL; AF297619; AAK97177.1; -; Genomic_DNA.
EMBL; AF297624; AAK97198.1; -; Genomic_DNA.
EMBL; AY128092; AAM96930.1; -; Genomic_DNA.
EMBL; AY161138; AAO12546.1; -; Genomic_DNA.
EMBL; AY161139; AAO12553.1; -; Genomic_DNA.
EMBL; AY233274; AAP79715.1; -; Genomic_DNA.
EMBL; AY233280; AAP79757.1; -; Genomic_DNA.
EMBL; AY233282; AAP79771.1; -; Genomic_DNA.
EMBL; AY233284; AAP79785.1; -; Genomic_DNA.
EMBL; AY233288; AAP79813.1; -; Genomic_DNA.
EMBL; AY233289; AAP79820.1; -; Genomic_DNA.
EMBL; AY603430; AAT44434.1; -; Genomic_DNA.
EMBL; AY603435; AAT44439.1; -; Genomic_DNA.
EMBL; AY603436; AAT44440.1; -; Genomic_DNA.
EMBL; AY707087; AAU44346.1; -; Genomic_DNA.
EMBL; AY902775; AAX07615.1; -; Genomic_DNA.
EMBL; AY934766; AAY25213.1; -; Genomic_DNA.
EMBL; AY934773; AAY25262.1; -; Genomic_DNA.
EMBL; DQ020002; AAY25275.1; -; Genomic_DNA.
EMBL; DQ315786; ABD37008.1; -; Genomic_DNA.
EMBL; EU086721; ABU63578.1; -; Genomic_DNA.
EMBL; EU594389; ACF95007.1; -; Genomic_DNA.
EMBL; EU594390; ACF95014.1; -; Genomic_DNA.
EMBL; EU594391; ACF95021.1; -; Genomic_DNA.
EMBL; EU594392; ACF95028.1; -; Genomic_DNA.
EMBL; EU594393; ACF95035.1; -; Genomic_DNA.
EMBL; EU594394; ACF95042.1; -; Genomic_DNA.
EMBL; EU594395; ACF95049.1; -; Genomic_DNA.
EMBL; EU594383; ACF95169.1; -; Genomic_DNA.
EMBL; EU594385; ACF95183.1; -; Genomic_DNA.
EMBL; EU594386; ACF95190.1; -; Genomic_DNA.
EMBL; EU594388; ACF95203.1; -; Genomic_DNA.
EMBL; EU859899; ACJ65854.1; -; Genomic_DNA.
EMBL; EU859900; ACJ65861.1; -; Genomic_DNA.
EMBL; EU859901; ACJ65868.1; -; Genomic_DNA.
EMBL; EU859902; ACJ65875.1; -; Genomic_DNA.
EMBL; EU859903; ACJ65882.1; -; Genomic_DNA.
EMBL; EU859904; ACJ65889.1; -; Genomic_DNA.
EMBL; EU859905; ACJ65896.1; -; Genomic_DNA.
EMBL; EU859906; ACJ65903.1; -; Genomic_DNA.
EMBL; EU859907; ACJ65910.1; -; Genomic_DNA.
EMBL; EU859908; ACJ65917.1; -; Genomic_DNA.
EMBL; EU859909; ACJ65924.1; -; Genomic_DNA.
EMBL; EU859910; ACJ65931.1; -; Genomic_DNA.
EMBL; EU859911; ACJ65938.1; -; Genomic_DNA.
EMBL; EU859913; ACJ65952.1; -; Genomic_DNA.
EMBL; EU859914; ACJ65959.1; -; Genomic_DNA.
EMBL; EU859915; ACJ65966.1; -; Genomic_DNA.
EMBL; EU859916; ACJ65973.1; -; Genomic_DNA.
EMBL; EU859917; ACJ65980.1; -; Genomic_DNA.
EMBL; EU859918; ACJ65987.1; -; Genomic_DNA.
EMBL; EU859920; ACJ66001.1; -; Genomic_DNA.
EMBL; EU859921; ACJ66008.1; -; Genomic_DNA.
EMBL; EU859922; ACJ66015.1; -; Genomic_DNA.
EMBL; EU859923; ACJ66022.1; -; Genomic_DNA.
EMBL; EU859924; ACJ66029.1; -; Genomic_DNA.
EMBL; EU859925; ACJ66036.1; -; Genomic_DNA.
EMBL; EU859926; ACJ66043.1; -; Genomic_DNA.
EMBL; EU859927; ACJ66050.1; -; Genomic_DNA.
EMBL; EU859928; ACJ66057.1; -; Genomic_DNA.
EMBL; EU859929; ACJ66064.1; -; Genomic_DNA.
EMBL; EU859930; ACJ66071.1; -; Genomic_DNA.
EMBL; EU859931; ACJ66078.1; -; Genomic_DNA.
EMBL; EU859932; ACJ66085.1; -; Genomic_DNA.
EMBL; EU859933; ACJ66092.1; -; Genomic_DNA.
EMBL; EU859937; ACJ66119.1; -; Genomic_DNA.
EMBL; EU859940; ACJ66139.1; -; Genomic_DNA.
EMBL; EU859941; ACJ66146.1; -; Genomic_DNA.
EMBL; EU859942; ACJ66153.1; -; Genomic_DNA.
EMBL; EU859943; ACJ66160.1; -; Genomic_DNA.
EMBL; EU859945; ACJ66174.1; -; Genomic_DNA.
EMBL; EU859946; ACJ66181.1; -; Genomic_DNA.
EMBL; EU859947; ACJ66188.1; -; Genomic_DNA.
EMBL; EU859948; ACJ66195.1; -; Genomic_DNA.
EMBL; EU859949; ACJ66201.1; -; Genomic_DNA.
EMBL; EU859950; ACJ66209.1; -; Genomic_DNA.
EMBL; EU859951; ACJ66216.1; -; Genomic_DNA.
EMBL; EU859953; ACJ66230.1; -; Genomic_DNA.
EMBL; EU859954; ACJ66237.1; -; Genomic_DNA.
EMBL; EU859955; ACJ66244.1; -; Genomic_DNA.
EMBL; EU859956; ACJ66251.1; -; Genomic_DNA.
EMBL; FJ349224; ACO89755.1; -; Genomic_DNA.
EMBL; GQ414522; ACV49872.1; -; Genomic_DNA.
EMBL; GQ477461; ACX69327.1; -; Genomic_DNA.
EMBL; GQ477503; ACX69604.1; -; Genomic_DNA.
EMBL; AF043580; ADB03200.1; -; Genomic_DNA.
EMBL; GU563546; ADX42328.1; -; Genomic_DNA.
EMBL; GU563548; ADX42341.1; -; Genomic_DNA.
EMBL; GU563553; ADX42365.1; -; Genomic_DNA.
EMBL; GU563554; ADX42372.1; -; Genomic_DNA.
EMBL; GU563555; ADX42379.1; -; Genomic_DNA.
EMBL; GU563557; ADX42392.1; -; Genomic_DNA.
EMBL; GU563558; ADX42399.1; -; Genomic_DNA.
EMBL; GU563562; ADX42426.1; -; Genomic_DNA.
EMBL; JQ687529; AFJ79459.1; -; Genomic_DNA.
EMBL; JN182321; AFL65062.1; -; Genomic_DNA.
EMBL; JN182324; AFL65082.1; -; Genomic_DNA.
EMBL; JN182330; AFL65125.1; -; Genomic_DNA.
EMBL; JN182331; AFL65132.1; -; Genomic_DNA.
EMBL; JN182333; AFL65146.1; -; Genomic_DNA.
EMBL; JX096952; AFQ36940.1; -; Genomic_DNA.
EMBL; KC836831; AGN92535.1; -; Genomic_DNA.
EMBL; KC836832; AGN92537.1; -; Genomic_DNA.
EMBL; KC836849; AGN92569.1; -; Genomic_DNA.
EMBL; KC836854; AGN92579.1; -; Genomic_DNA.
EMBL; KC836877; AGN92626.1; -; Genomic_DNA.
EMBL; KC836880; AGN92639.1; -; Genomic_DNA.
EMBL; KC836881; AGN92645.1; -; Genomic_DNA.
EMBL; KJ010776; AHM26212.1; -; Genomic_DNA.
EMBL; KJ010777; AHM26219.1; -; Genomic_DNA.
EMBL; KJ010778; AHM26226.1; -; Genomic_DNA.
EMBL; KJ843166; AIJ49843.1; -; Genomic_DNA.
EMBL; KJ843173; AIJ49892.1; -; Genomic_DNA.
EMBL; KJ843186; AIJ49983.1; -; Genomic_DNA.
EMBL; KJ843188; AIJ49996.1; -; Genomic_DNA.
EMBL; KJ843192; AIJ50024.1; -; Genomic_DNA.
EMBL; KJ843214; AIJ50177.1; -; Genomic_DNA.
EMBL; KJ843215; AIJ50184.1; -; Genomic_DNA.
EMBL; KJ843216; AIJ50191.1; -; Genomic_DNA.
EMBL; KJ843217; AIJ50198.1; -; Genomic_DNA.
EMBL; KJ843218; AIJ50205.1; -; Genomic_DNA.
EMBL; KM606648; AIW67670.1; -; Genomic_DNA.
EMBL; KM606652; AIW67685.1; -; Genomic_DNA.
EMBL; KM606660; AIW67713.1; -; Genomic_DNA.
EMBL; KM606663; AIW67724.1; -; Genomic_DNA.
EMBL; KM606669; AIW67746.1; -; Genomic_DNA.
EMBL; KM606674; AIW67764.1; -; Genomic_DNA.
EMBL; KM606676; AIW67771.1; -; Genomic_DNA.
EMBL; KM606677; AIW67775.1; -; Genomic_DNA.
EMBL; KM606678; AIW67778.1; -; Genomic_DNA.
EMBL; KM606680; AIW67787.1; -; Genomic_DNA.
EMBL; KM606683; AIW67797.1; -; Genomic_DNA.
EMBL; KM606684; AIW67801.1; -; Genomic_DNA.
EMBL; KM606685; AIW67805.1; -; Genomic_DNA.
EMBL; KM606687; AIW67811.1; -; Genomic_DNA.
EMBL; KM606691; AIW67825.1; -; Genomic_DNA.
EMBL; KM606694; AIW67834.1; -; Genomic_DNA.
EMBL; KM606746; AIW68011.1; -; Genomic_DNA.
EMBL; KM606749; AIW68028.1; -; Genomic_DNA.
EMBL; KP234050; AIZ50124.1; -; Genomic_DNA.
EMBL; KM519453; AIZ95353.1; -; Genomic_DNA.
EMBL; KM519454; AIZ95360.1; -; Genomic_DNA.
EMBL; KP718087; AKZ16460.1; -; Genomic_DNA.
EMBL; KP718088; AKZ16465.1; -; Genomic_DNA.
EMBL; KP718091; AKZ16480.1; -; Genomic_DNA.
EMBL; KP718097; AKZ16510.1; -; Genomic_DNA.
EMBL; KP718098; AKZ16515.1; -; Genomic_DNA.
EMBL; KP718099; AKZ16520.1; -; Genomic_DNA.
EMBL; KP168423; ALG02601.1; -; Genomic_DNA.
EMBL; KP168424; ALG02608.1; -; Genomic_DNA.
EMBL; KP168434; ALG02676.1; -; Genomic_DNA.
EMBL; KP274925; ALI58685.1; -; Genomic_DNA.
EMBL; KP274927; ALI58698.1; -; Genomic_DNA.
EMBL; KT347087; ALS87636.1; -; Genomic_DNA.
EMBL; KT347088; ALS87640.1; -; Genomic_DNA.
EMBL; KU605532; ANH21981.1; -; Genomic_DNA.
EMBL; KU605534; ANH21996.1; -; Genomic_DNA.
EMBL; KU605535; ANH22003.1; -; Genomic_DNA.
EMBL; KU605537; ANH22016.1; -; Genomic_DNA.
EMBL; KU605538; ANH22023.1; -; Genomic_DNA.
EMBL; KU605539; ANH22030.1; -; Genomic_DNA.
EMBL; KX648548; ANZ72792.1; -; Genomic_DNA.
EMBL; KY003230; APD28360.1; -; Genomic_RNA.
EMBL; AB076678; BAC10530.1; -; Genomic_DNA.
EMBL; AB116077; BAD08466.1; -; Genomic_DNA.
EMBL; AB116079; BAD08472.1; -; Genomic_DNA.
EMBL; AB116080; BAD08475.1; -; Genomic_DNA.
EMBL; AB246337; BAF36018.1; -; Genomic_DNA.
EMBL; AB246338; BAF36020.1; -; Genomic_DNA.
EMBL; AB300366; BAF81670.1; -; Genomic_DNA.
EMBL; AB300367; BAF81674.1; -; Genomic_DNA.
EMBL; AB453979; BAG68743.1; -; Genomic_DNA.
EMBL; AB453980; BAG68747.1; -; Genomic_DNA.
EMBL; AB453981; BAG68751.1; -; Genomic_DNA.
EMBL; AB453984; BAG68762.1; -; Genomic_DNA.
EMBL; AB549213; BAI81984.1; -; Genomic_DNA.
EMBL; AB480038; BAJ15851.1; -; Genomic_DNA.
EMBL; AB480039; BAJ15855.1; -; Genomic_DNA.
EMBL; AB480041; BAJ15863.1; -; Genomic_DNA.
EMBL; AB697488; BAL60911.1; -; Genomic_DNA.
EMBL; AB697489; BAL60918.1; -; Genomic_DNA.
EMBL; AB697492; BAL60939.1; -; Genomic_DNA.
EMBL; AB697493; BAL60946.1; -; Genomic_DNA.
EMBL; AB697495; BAL60960.1; -; Genomic_DNA.
EMBL; AB697496; BAL60967.1; -; Genomic_DNA.
EMBL; AB697497; BAL60974.1; -; Genomic_DNA.
EMBL; AB697499; BAL60988.1; -; Genomic_DNA.
EMBL; AB697501; BAL61002.1; -; Genomic_DNA.
EMBL; AB697503; BAL61015.1; -; Genomic_DNA.
EMBL; AB697504; BAL61022.1; -; Genomic_DNA.
EMBL; AB697505; BAL61029.1; -; Genomic_DNA.
EMBL; AB697506; BAL61036.1; -; Genomic_DNA.
EMBL; AB697507; BAL61043.1; -; Genomic_DNA.
EMBL; AB697508; BAL61050.1; -; Genomic_DNA.
EMBL; AB697509; BAL61057.1; -; Genomic_DNA.
EMBL; AB697512; BAL61077.1; -; Genomic_DNA.
EMBL; AB775198; BAN66668.1; -; Genomic_DNA.
EMBL; AB775199; BAN66672.1; -; Genomic_DNA.
EMBL; AB775200; BAN66676.1; -; Genomic_DNA.
EMBL; AB775201; BAN66680.1; -; Genomic_DNA.
EMBL; AB937792; BAP81747.1; -; Genomic_DNA.
EMBL; AB937793; BAP81751.1; -; Genomic_DNA.
EMBL; AB937794; BAP81755.1; -; Genomic_DNA.
EMBL; AB937798; BAP81771.1; -; Genomic_DNA.
EMBL; X07911; CAA30747.1; -; Genomic_DNA.
EMBL; Z72478; CAA96555.1; -; Genomic_DNA.
EMBL; AM295795; CAL29858.1; -; Genomic_DNA.
EMBL; AM295797; CAL29872.1; -; Genomic_DNA.
EMBL; AM295800; CAL29887.1; -; Genomic_DNA.
EMBL; AM410963; CAL69432.1; -; Genomic_DNA.
PIR; C94409; NKVLA3.
PIR; S01405; S01405.
PIR; S33686; S33686.
Proteomes; UP000095917; Genome.
Proteomes; UP000097177; Genome.
Proteomes; UP000097206; Genome.
Proteomes; UP000097454; Genome.
Proteomes; UP000097734; Genome.
Proteomes; UP000098224; Genome.
Proteomes; UP000098381; Genome.
Proteomes; UP000098849; Genome.
Proteomes; UP000099050; Genome.
Proteomes; UP000099814; Genome.
Proteomes; UP000100042; Genome.
Proteomes; UP000100674; Genome.
Proteomes; UP000100713; Genome.
Proteomes; UP000100868; Genome.
Proteomes; UP000101062; Genome.
Proteomes; UP000101147; Genome.
Proteomes; UP000101357; Genome.
Proteomes; UP000101428; Genome.
Proteomes; UP000101626; Genome.
Proteomes; UP000101673; Genome.
Proteomes; UP000101771; Genome.
Proteomes; UP000101795; Genome.
Proteomes; UP000101878; Genome.
Proteomes; UP000101998; Genome.
Proteomes; UP000102483; Genome.
Proteomes; UP000102520; Genome.
Proteomes; UP000102780; Genome.
Proteomes; UP000102873; Genome.
Proteomes; UP000103056; Genome.
Proteomes; UP000103322; Genome.
Proteomes; UP000104429; Genome.
Proteomes; UP000104884; Genome.
Proteomes; UP000105088; Genome.
Proteomes; UP000107483; Genome.
Proteomes; UP000107699; Genome.
Proteomes; UP000109884; Genome.
Proteomes; UP000109895; Genome.
Proteomes; UP000112781; Genome.
Proteomes; UP000112905; Genome.
Proteomes; UP000113138; Genome.
Proteomes; UP000113756; Genome.
Proteomes; UP000114184; Genome.
Proteomes; UP000114457; Genome.
Proteomes; UP000114931; Genome.
Proteomes; UP000115007; Genome.
Proteomes; UP000115590; Genome.
Proteomes; UP000115794; Genome.
Proteomes; UP000116012; Genome.
Proteomes; UP000116322; Genome.
Proteomes; UP000116629; Genome.
Proteomes; UP000116710; Genome.
Proteomes; UP000117011; Genome.
Proteomes; UP000117236; Genome.
Proteomes; UP000118571; Genome.
Proteomes; UP000119150; Genome.
Proteomes; UP000119342; Genome.
Proteomes; UP000120227; Genome.
Proteomes; UP000120637; Genome.
Proteomes; UP000121032; Genome.
Proteomes; UP000121822; Genome.
Proteomes; UP000123313; Genome.
Proteomes; UP000123417; Genome.
Proteomes; UP000123557; Genome.
Proteomes; UP000124116; Genome.
Proteomes; UP000124635; Genome.
Proteomes; UP000124849; Genome.
Proteomes; UP000126535; Genome.
Proteomes; UP000127137; Genome.
Proteomes; UP000127894; Genome.
Proteomes; UP000128232; Genome.
Proteomes; UP000128492; Genome.
Proteomes; UP000128855; Genome.
Proteomes; UP000128971; Genome.
Proteomes; UP000129397; Genome.
Proteomes; UP000129703; Genome.
Proteomes; UP000129955; Genome.
Proteomes; UP000130412; Genome.
Proteomes; UP000130632; Genome.
Proteomes; UP000130867; Genome.
Proteomes; UP000131132; Genome.
Proteomes; UP000131214; Genome.
Proteomes; UP000131622; Genome.
Proteomes; UP000131654; Genome.
Proteomes; UP000132474; Genome.
Proteomes; UP000133211; Genome.
Proteomes; UP000135397; Genome.
Proteomes; UP000135770; Genome.
Proteomes; UP000135880; Genome.
Proteomes; UP000135904; Genome.
Proteomes; UP000137987; Genome.
Proteomes; UP000138019; Genome.
Proteomes; UP000138848; Genome.
Proteomes; UP000138877; Genome.
Proteomes; UP000139217; Genome.
Proteomes; UP000139412; Genome.
Proteomes; UP000139693; Genome.
Proteomes; UP000140042; Genome.
Proteomes; UP000140356; Genome.
Proteomes; UP000141232; Genome.
Proteomes; UP000141345; Genome.
Proteomes; UP000142265; Genome.
Proteomes; UP000142530; Genome.
Proteomes; UP000142567; Genome.
Proteomes; UP000142886; Genome.
Proteomes; UP000143017; Genome.
Proteomes; UP000143248; Genome.
Proteomes; UP000143451; Genome.
Proteomes; UP000143721; Genome.
Proteomes; UP000145790; Genome.
Proteomes; UP000145853; Genome.
Proteomes; UP000146270; Genome.
Proteomes; UP000146952; Genome.
Proteomes; UP000147108; Genome.
Proteomes; UP000147490; Genome.
Proteomes; UP000147734; Genome.
Proteomes; UP000147983; Genome.
Proteomes; UP000148039; Genome.
Proteomes; UP000148058; Genome.
Proteomes; UP000148793; Genome.
Proteomes; UP000149021; Genome.
Proteomes; UP000149420; Genome.
Proteomes; UP000150141; Genome.
Proteomes; UP000151241; Genome.
Proteomes; UP000151937; Genome.
Proteomes; UP000152026; Genome.
Proteomes; UP000153066; Genome.
Proteomes; UP000154286; Genome.
Proteomes; UP000154311; Genome.
Proteomes; UP000154513; Genome.
Proteomes; UP000155540; Genome.
Proteomes; UP000155744; Genome.
Proteomes; UP000155768; Genome.
Proteomes; UP000156294; Genome.
Proteomes; UP000157412; Genome.
Proteomes; UP000157421; Genome.
Proteomes; UP000157482; Genome.
Proteomes; UP000158092; Genome.
Proteomes; UP000158149; Genome.
Proteomes; UP000158751; Genome.
Proteomes; UP000159193; Genome.
Proteomes; UP000159396; Genome.
Proteomes; UP000159470; Genome.
Proteomes; UP000159513; Genome.
Proteomes; UP000160152; Genome.
Proteomes; UP000160632; Genome.
Proteomes; UP000161045; Genome.
Proteomes; UP000161098; Genome.
Proteomes; UP000161965; Genome.
Proteomes; UP000162620; Genome.
Proteomes; UP000162724; Genome.
Proteomes; UP000163148; Genome.
Proteomes; UP000164137; Genome.
Proteomes; UP000164548; Genome.
Proteomes; UP000165165; Genome.
Proteomes; UP000165483; Genome.
Proteomes; UP000165795; Genome.
Proteomes; UP000166009; Genome.
Proteomes; UP000166107; Genome.
Proteomes; UP000166261; Genome.
Proteomes; UP000166352; Genome.
Proteomes; UP000167124; Genome.
Proteomes; UP000167306; Genome.
Proteomes; UP000167409; Genome.
Proteomes; UP000167474; Genome.
Proteomes; UP000167660; Genome.
Proteomes; UP000167875; Genome.
Proteomes; UP000168066; Genome.
Proteomes; UP000168544; Genome.
Proteomes; UP000168864; Genome.
Proteomes; UP000168892; Genome.
Proteomes; UP000169555; Genome.
Proteomes; UP000169785; Genome.
Proteomes; UP000170781; Genome.
Proteomes; UP000171502; Genome.
Proteomes; UP000171965; Genome.
Proteomes; UP000172068; Genome.
Proteomes; UP000172254; Genome.
Proteomes; UP000172264; Genome.
Proteomes; UP000173368; Genome.
Proteomes; UP000173551; Genome.
Proteomes; UP000173732; Genome.
Proteomes; UP000174122; Genome.
Proteomes; UP000174580; Genome.
Proteomes; UP000174598; Genome.
Proteomes; UP000175223; Genome.
Proteomes; UP000180970; Genome.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0039619; C:T=4 icosahedral viral capsid; IEA:UniProtKB-UniRule.
GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
GO; GO:0005198; F:structural molecule activity; IEA:UniProtKB-UniRule.
GO; GO:0030683; P:evasion or tolerance by virus of host immune response; IEA:UniProtKB-KW.
GO; GO:0075521; P:microtubule-dependent intracellular transport of viral material towards nucleus; IEA:UniProtKB-UniRule.
GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-UniRule.
GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-UniRule.
GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-UniRule.
Gene3D; 1.10.4090.10; -; 1.
HAMAP; MF_04076; HBV_HBEAG; 1.
InterPro; IPR013195; Hepatitis_B_virus_capsid_N.
InterPro; IPR002006; Hepatitis_core.
InterPro; IPR036459; Viral_capsid_core_dom_sf_HBV.
Pfam; PF08290; Hep_core_N; 1.
Pfam; PF00906; Hepatitis_core; 3.
ProDom; PD000874; Vir_capsid_Znf-put_N_Hepatitis; 1.
SUPFAM; SSF47852; SSF47852; 1.
2: Evidence at transcript level;
Capsid protein {ECO:0000256|HAMAP-Rule:MF_04076};
Complete proteome {ECO:0000313|Proteomes:UP000095917,
ECO:0000313|Proteomes:UP000097177, ECO:0000313|Proteomes:UP000097206,
ECO:0000313|Proteomes:UP000097454};
Cytoplasmic inwards viral transport {ECO:0000256|HAMAP-Rule:MF_04076};
DNA-binding {ECO:0000256|HAMAP-Rule:MF_04076};
Host cytoplasm {ECO:0000256|HAMAP-Rule:MF_04076};
Host-virus interaction {ECO:0000256|HAMAP-Rule:MF_04076,
ECO:0000256|RuleBase:RU361253};
Microtubular inwards viral transport {ECO:0000256|HAMAP-
Rule:MF_04076}; Phosphoprotein {ECO:0000256|HAMAP-Rule:MF_04076};
Repeat {ECO:0000256|HAMAP-Rule:MF_04076,
ECO:0000256|SAAS:SAAS00779256};
RNA-binding {ECO:0000256|HAMAP-Rule:MF_04076};
T=4 icosahedral capsid protein {ECO:0000256|HAMAP-Rule:MF_04076};
Viral immunoevasion {ECO:0000256|RuleBase:RU361253};
Viral nucleoprotein {ECO:0000313|EMBL:CAA30747.1};
Viral penetration into host nucleus {ECO:0000256|HAMAP-Rule:MF_04076};
Virion {ECO:0000256|HAMAP-Rule:MF_04076, ECO:0000313|EMBL:CAA30747.1};
Virus entry into host cell {ECO:0000256|HAMAP-Rule:MF_04076}.
DOMAIN 1 27 Hep_core_N. {ECO:0000259|Pfam:PF08290}.
REGION 208 214 RNA binding. {ECO:0000256|HAMAP-
Rule:MF_04076}.
MOTIF 189 206 Bipartite nuclear localization signal.
{ECO:0000256|HAMAP-Rule:MF_04076}.
MOD_RES 186 186 Phosphoserine; by host.
{ECO:0000256|HAMAP-Rule:MF_04076}.
MOD_RES 193 193 Phosphoserine; by host.
{ECO:0000256|HAMAP-Rule:MF_04076}.
MOD_RES 201 201 Phosphoserine; by host.
{ECO:0000256|HAMAP-Rule:MF_04076}.
SEQUENCE 214 AA; 24643 MW; B7068333FC905D02 CRC64;
MQLFHLCLII SCTCPTVQAS KLCLGWLWGM DIDPYKEFGA TVELLSFLPS DFFPSVRDLL
DTASALYREA LESPEHCSPH HTALRQAILC WGELMTLATW VGNNLEDPAS RDLVVNYVNT
NMGLKIRQLL WFHISCLTFG RETVLEYLVS FGVWIRTPPA YRPPNAPILS TLPETTVVRR
RDRGRSPRRR TPSPRRRRSQ SPRRRRSQSR ESQC


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