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Carbonic anhydrase-related protein 11 (CA-RP XI) (CA-XI) (CARP XI) (Carbonic anhydrase-related protein 2) (CA-RP II) (CARP-2)

 CAH11_MOUSE             Reviewed;         328 AA.
O70354; Q8VEA9;
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
09-MAY-2003, sequence version 2.
25-OCT-2017, entry version 122.
RecName: Full=Carbonic anhydrase-related protein 11;
AltName: Full=CA-RP XI;
Short=CA-XI;
Short=CARP XI;
AltName: Full=Carbonic anhydrase-related protein 2;
Short=CA-RP II;
Short=CARP-2;
Flags: Precursor;
Name=Ca11; Synonyms=Car11, Carp2;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
Taniuchi K., Nishimori I.;
"A novel CA-RP XI gene.";
Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[3]
NUCLEOTIDE SEQUENCE [MRNA] OF 48-251.
TISSUE=Brain;
PubMed=9878252; DOI=10.1006/geno.1998.5585;
Lovejoy D.A., Hewett-Emmett D., Porter C.A., Cepoi D., Sheffield A.,
Vale W.W., Tashian R.E.;
"Evolutionarily conserved, 'acatalytic' carbonic anhydrase-related
protein XI contains a sequence motif present in the neuropeptide
sauvagine: the human CA-RP XI gene (CA11) is embedded between the
secretor gene cluster and the DBP gene at 19q13.3.";
Genomics 54:484-493(1998).
-!- FUNCTION: Does not have a catalytic activity.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
-!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
{ECO:0000305}.
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EMBL; AB079601; BAC07262.1; -; mRNA.
EMBL; BC019393; AAH19393.1; -; mRNA.
EMBL; AF050105; AAD08801.1; -; mRNA.
CCDS; CCDS21259.1; -.
RefSeq; NP_033930.1; NM_009800.4.
UniGene; Mm.27736; -.
ProteinModelPortal; O70354; -.
SMR; O70354; -.
STRING; 10090.ENSMUSP00000003360; -.
iPTMnet; O70354; -.
PhosphoSitePlus; O70354; -.
PaxDb; O70354; -.
PRIDE; O70354; -.
Ensembl; ENSMUST00000003360; ENSMUSP00000003360; ENSMUSG00000003273.
GeneID; 12348; -.
KEGG; mmu:12348; -.
UCSC; uc009gwr.1; mouse.
CTD; 12348; -.
MGI; MGI:1336193; Car11.
eggNOG; KOG0382; Eukaryota.
eggNOG; COG3338; LUCA.
GeneTree; ENSGT00740000115510; -.
HOGENOM; HOG000019899; -.
HOVERGEN; HBG097666; -.
InParanoid; O70354; -.
OMA; AVSWEEW; -.
OrthoDB; EOG091G0T4J; -.
PhylomeDB; O70354; -.
TreeFam; TF352926; -.
PRO; PR:O70354; -.
Proteomes; UP000000589; Chromosome 7.
Bgee; ENSMUSG00000003273; -.
CleanEx; MM_CAR11; -.
ExpressionAtlas; O70354; baseline and differential.
Genevisible; O70354; MM.
GO; GO:0016323; C:basolateral plasma membrane; IDA:UniProtKB.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
Gene3D; 3.10.200.10; -; 1.
InterPro; IPR001148; Carbonic_anhydrase_a.
InterPro; IPR023561; Carbonic_anhydrase_a-class.
InterPro; IPR036398; Carbonic_anhydrase_a_sf.
PANTHER; PTHR18952; PTHR18952; 1.
Pfam; PF00194; Carb_anhydrase; 1.
SMART; SM01057; Carb_anhydrase; 1.
SUPFAM; SSF51069; SSF51069; 1.
PROSITE; PS51144; ALPHA_CA_2; 1.
2: Evidence at transcript level;
Complete proteome; Glycoprotein; Reference proteome; Secreted; Signal.
SIGNAL 1 23 {ECO:0000255}.
CHAIN 24 328 Carbonic anhydrase-related protein 11.
/FTId=PRO_0000004246.
DOMAIN 33 303 Alpha-carbonic anhydrase.
{ECO:0000255|PROSITE-ProRule:PRU01134}.
CARBOHYD 118 118 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
SEQUENCE 328 AA; 36051 MW; 483E9770CC4362FD CRC64;
MGGAARLSAP QALVLWAALG AAAHIGPAPD PEDWWSYKEN LQGNFVPGPP FWGLVNAAWS
LCAVGKRQSP VDVELKRVLY DPFLPPLRLS TGGEKLRGTL YNTGRHVSFL PASRPVVNVS
GGPLLYSHRL SELRLLFGAR DGAGSEHQIN HEGFSAEVQL IHFNQELYGN LSAASRGPNG
LAILSLFVNV AGSSNPFLSR LLNRDTITRI SYKNDAYFLQ DLSLELLFPE SFGFITYQGS
LSTPPCSETV TWILIDRALN ITSLQMHSLR LLSQNPPSQI FQSLSGNGRP LQPLAHRALR
GNRDPRHPER RCRGPNYRLH VDGGPHGR


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