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Cardiac troponin T (Troponin T2, cardiac)

 Q7ZSY4_DANRE            Unreviewed;       282 AA.
Q7ZSY4;
01-JUN-2003, integrated into UniProtKB/TrEMBL.
01-JUN-2003, sequence version 1.
05-JUL-2017, entry version 75.
SubName: Full=Cardiac troponin T {ECO:0000313|EMBL:AAO50210.1};
SubName: Full=Troponin T2, cardiac {ECO:0000313|EMBL:AAI53912.1};
Name=tnnt2a {ECO:0000313|ZFIN:ZDB-GENE-000626-1};
Synonyms=tnnt2 {ECO:0000313|EMBL:AAO50210.1,
ECO:0000313|ZFIN:ZDB-GENE-000626-1};
Danio rerio (Zebrafish) (Brachydanio rerio).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
Cyprinidae; Danio.
NCBI_TaxID=7955 {ECO:0000313|EMBL:AAO50210.1};
[1] {ECO:0000313|EMBL:AAI53912.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Heart {ECO:0000313|EMBL:AAI53912.1};
PubMed=12477932; DOI=10.1073/pnas.242603899;
Mammalian Gene Collection Program Team;
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD,
Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B,
Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T,
Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA,
Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL,
Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P,
Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ,
Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S,
Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM,
Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A,
Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y,
Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC,
Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS,
Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE,
Jones SJ Marra.MA.;
"Generation and initial analysis of more than 15,000 full-length human
and mouse cDNA sequences.";
Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
[2] {ECO:0000313|EMBL:AAO50210.1}
NUCLEOTIDE SEQUENCE.
STRAIN=AB {ECO:0000313|EMBL:AAO50210.1};
TISSUE=Heart {ECO:0000313|EMBL:AAO50210.1};
PubMed=12761854; DOI=10.1002/dvdy.10305;
Hsiao C.D., Tsai W.Y., Horng L.S., Tsai H.J.;
"Molecular structure and developmental expression of three muscle-type
troponin T genes in zebrafish.";
Dev. Dyn. 227:266-279(2003).
[3] {ECO:0000313|EMBL:AAI53912.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Heart {ECO:0000313|EMBL:AAI53912.1};
NIH MGC Project;
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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Distributed under the Creative Commons Attribution-NoDerivs License
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EMBL; BC153911; AAI53912.1; -; mRNA.
EMBL; AF434187; AAO50210.1; -; mRNA.
EMBL; AF512525; AAP33153.1; -; Genomic_DNA.
UniGene; Dr.14260; -.
ZFIN; ZDB-GENE-000626-1; tnnt2a.
eggNOG; KOG3634; Eukaryota.
eggNOG; ENOG410XS6A; LUCA.
HOVERGEN; HBG052790; -.
GO; GO:0005861; C:troponin complex; IMP:ZFIN.
GO; GO:0060840; P:artery development; IMP:ZFIN.
GO; GO:0008015; P:blood circulation; IMP:ZFIN.
GO; GO:0001568; P:blood vessel development; IMP:ZFIN.
GO; GO:0001569; P:branching involved in blood vessel morphogenesis; IMP:ZFIN.
GO; GO:0060047; P:heart contraction; IMP:ZFIN.
GO; GO:0007507; P:heart development; IMP:ZFIN.
GO; GO:0060218; P:hematopoietic stem cell differentiation; IMP:ZFIN.
GO; GO:0097535; P:lymphoid lineage cell migration into thymus; IMP:ZFIN.
GO; GO:0006809; P:nitric oxide biosynthetic process; IMP:ZFIN.
GO; GO:0048793; P:pronephros development; IMP:ZFIN.
GO; GO:0008016; P:regulation of heart contraction; IMP:ZFIN.
GO; GO:0006937; P:regulation of muscle contraction; IEA:InterPro.
GO; GO:0010749; P:regulation of nitric oxide mediated signal transduction; IDA:ZFIN.
GO; GO:0045214; P:sarcomere organization; IMP:ZFIN.
GO; GO:0006941; P:striated muscle contraction; IMP:ZFIN.
GO; GO:0001944; P:vasculature development; IMP:ZFIN.
GO; GO:0048845; P:venous blood vessel morphogenesis; IMP:ZFIN.
GO; GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:ZFIN.
GO; GO:0021591; P:ventricular system development; IMP:ZFIN.
InterPro; IPR027707; TNNT.
InterPro; IPR001978; Troponin.
PANTHER; PTHR11521; PTHR11521; 1.
Pfam; PF00992; Troponin; 1.
2: Evidence at transcript level;
Coiled coil {ECO:0000256|SAM:Coils}.
COILED 3 38 {ECO:0000256|SAM:Coils}.
COILED 94 180 {ECO:0000256|SAM:Coils}.
SEQUENCE 282 AA; 33952 MW; E6DEF2B80FA91D25 CRC64;
MSDNEEVEEY EEQEEEQVEE EEEVQEEAQH DEEAQQEENA GGDEETTQEH DGEEETEDGG
EEAKPKFLKP FMLPNLVPPK IPDGERVDFD DIHRKRMEKD LNELQTLIEA HFESRKKEEE
EIISLKDRIE KRRSERAEQQ RIRSERERER QKRLEEERAR KEEEEAKKRA EDDAKKKKTL
TSLHFGGYMQ KIERRSGKKQ TEREKKKKIL GDRRKPLDID NANESALREK AKELWSWMRE
LEAEKFELQY QFGKQKYEIN VLRNRVSDHQ KTSKRTKRGL RK


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