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Casein kinase II beta subunit, isoform I (EC 2.7.11.-)

 M9NDU6_DROME            Unreviewed;       233 AA.
M9NDU6;
26-JUN-2013, integrated into UniProtKB/TrEMBL.
26-JUN-2013, sequence version 1.
05-DEC-2018, entry version 46.
SubName: Full=Casein kinase II beta subunit, isoform I {ECO:0000313|EMBL:AFH07343.1};
EC=2.7.11.- {ECO:0000313|EMBL:AFH07343.1};
Name=CkIIbeta {ECO:0000313|EMBL:AFH07343.1,
ECO:0000313|FlyBase:FBgn0000259};
Synonyms=And {ECO:0000313|EMBL:AFH07343.1},
betaCK2 {ECO:0000313|EMBL:AFH07343.1},
Cask-II-b {ECO:0000313|EMBL:AFH07343.1},
CCK2 {ECO:0000313|EMBL:AFH07343.1},
CK II {ECO:0000313|EMBL:AFH07343.1},
CK-2 {ECO:0000313|EMBL:AFH07343.1},
CK-II beta {ECO:0000313|EMBL:AFH07343.1},
CK-IIbeta {ECO:0000313|EMBL:AFH07343.1},
Ck-IIbeta {ECO:0000313|EMBL:AFH07343.1},
CK2 {ECO:0000313|EMBL:AFH07343.1},
CK2-beta {ECO:0000313|EMBL:AFH07343.1},
CK2beta {ECO:0000313|EMBL:AFH07343.1},
Ck2beta {ECO:0000313|EMBL:AFH07343.1},
ck2beta {ECO:0000313|EMBL:AFH07343.1},
CKII {ECO:0000313|EMBL:AFH07343.1},
CkII {ECO:0000313|EMBL:AFH07343.1},
CKII beta {ECO:0000313|EMBL:AFH07343.1},
CkII-beta {ECO:0000313|EMBL:AFH07343.1},
CKII-beta1 {ECO:0000313|EMBL:AFH07343.1},
CKIIb {ECO:0000313|EMBL:AFH07343.1},
CKIIbeta {ECO:0000313|EMBL:AFH07343.1},
Ckiibeta {ECO:0000313|EMBL:AFH07343.1},
CkIIbeta1 {ECO:0000313|EMBL:AFH07343.1},
dCK2beta {ECO:0000313|EMBL:AFH07343.1},
dCKII {ECO:0000313|EMBL:AFH07343.1},
dCKII beta {ECO:0000313|EMBL:AFH07343.1},
Dm-CK2-beta {ECO:0000313|EMBL:AFH07343.1},
DmCK2beta {ECO:0000313|EMBL:AFH07343.1},
DmCKIIbeta {ECO:0000313|EMBL:AFH07343.1},
DmCkIIbeta {ECO:0000313|EMBL:AFH07343.1},
Dmel\CG15224 {ECO:0000313|EMBL:AFH07343.1},
Ds cas kin {ECO:0000313|EMBL:AFH07343.1},
KC2B_DROME {ECO:0000313|EMBL:AFH07343.1},
mbu {ECO:0000313|EMBL:AFH07343.1};
ORFNames=CG15224 {ECO:0000313|EMBL:AFH07343.1,
ECO:0000313|FlyBase:FBgn0000259},
Dmel_CG15224 {ECO:0000313|EMBL:AFH07343.1};
Drosophila melanogaster (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=7227 {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803};
[1] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=10731132; DOI=10.1126/science.287.5461.2185;
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
"The genome sequence of Drosophila melanogaster.";
Science 287:2185-2195(2000).
[2] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537568;
Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
"Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence.";
Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
[3] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
GENOME REANNOTATION.
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
Lewis S.E.;
"Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review.";
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
[4] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537573;
Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
Ashburner M., Celniker S.E.;
"The transposable elements of the Drosophila melanogaster euchromatin:
a genomics perspective.";
Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
[5] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537574;
Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
Karpen G.H.;
"Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly.";
Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
[6] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
Ashburner M., Anxolabehere D.;
"Combined evidence annotation of transposable elements in genome
sequences.";
PLoS Comput. Biol. 1:166-175(2005).
[7] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=17569856; DOI=10.1126/science.1139815;
Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
"The Release 5.1 annotation of Drosophila melanogaster
heterochromatin.";
Science 316:1586-1591(2007).
[8] {ECO:0000313|EMBL:AFH07343.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=17569867; DOI=10.1126/science.1139816;
Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
Dimitri P., Karpen G.H., Celniker S.E.;
"Sequence finishing and mapping of Drosophila melanogaster
heterochromatin.";
Science 316:1625-1628(2007).
-----------------------------------------------------------------------
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EMBL; AE014298; AFH07343.1; -; Genomic_DNA.
RefSeq; NP_001245629.1; NM_001258700.2.
UniGene; Dm.142; -.
ProteinModelPortal; M9NDU6; -.
SMR; M9NDU6; -.
EnsemblMetazoa; FBtr0308084; FBpp0300427; FBgn0000259.
GeneID; 32132; -.
CTD; 32132; -.
FlyBase; FBgn0000259; CkIIbeta.
eggNOG; KOG3092; Eukaryota.
eggNOG; COG5041; LUCA.
GeneTree; ENSGT00390000003781; -.
OrthoDB; EOG091G0L2H; -.
ChiTaRS; CkIIbeta; fly.
GenomeRNAi; 32132; -.
Proteomes; UP000000803; Chromosome X.
Bgee; FBgn0000259; Expressed in 31 organ(s), highest expression level in egg chamber.
ExpressionAtlas; M9NDU6; baseline and differential.
GO; GO:0005956; C:protein kinase CK2 complex; IEA:InterPro.
GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
GO; GO:0019887; F:protein kinase regulator activity; IEA:InterPro.
Gene3D; 1.10.1820.10; -; 1.
InterPro; IPR016149; Casein_kin_II_reg-sub_N.
InterPro; IPR035991; Casein_kinase_II_beta_like.
InterPro; IPR000704; Casein_kinase_II_reg-sub.
PANTHER; PTHR11740; PTHR11740; 1.
Pfam; PF01214; CK_II_beta; 1.
PRINTS; PR00472; CASNKINASEII.
SMART; SM01085; CK_II_beta; 1.
SUPFAM; SSF57798; SSF57798; 1.
PROSITE; PS01101; CK2_BETA; 1.
1: Evidence at protein level;
Complete proteome {ECO:0000313|Proteomes:UP000000803};
Kinase {ECO:0000313|EMBL:AFH07343.1};
Proteomics identification {ECO:0000213|PeptideAtlas:M9NDU6};
Reference proteome {ECO:0000313|Proteomes:UP000000803};
Transferase {ECO:0000313|EMBL:AFH07343.1}.
SEQUENCE 233 AA; 26831 MW; 0BBDC3161EF2F563 CRC64;
MSSSEEVSWV TWFCGLRGNE FFCEVDEDYI QDKFNLTGLN EQVPNYRQAL DMILDLEPED
ELEDNPLQSD MTEQAAEMLY GLIHARYILT NRGIAQMIEK YQTGDFGHCP RVYCESQPML
PLGLSDIPGE AMVKTYCPKC IDVYTPKSSR HHHTDGAYFG TGFPHMLFMV HPEYRPKRPT
NQFVPRLYGF KIHSLAYQIQ LQAAANFKMP LRADYIALCQ EILSRPDPEA EAE


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