Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Casparian strip membrane protein 1 (AtCASP1)

 CASP1_ARATH             Reviewed;         206 AA.
Q9SIH4;
23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
23-MAY-2018, entry version 94.
RecName: Full=Casparian strip membrane protein 1;
Short=AtCASP1;
Name=CASP1; OrderedLocusNames=At2g36100; ORFNames=F9C22.3;
Arabidopsis thaliana (Mouse-ear cress).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
Arabidopsis.
NCBI_TaxID=3702;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
PubMed=10617197; DOI=10.1038/45471;
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L.,
Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L.,
Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H.,
Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D.,
Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M.,
Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis
thaliana.";
Nature 402:761-768(1999).
[2]
GENOME REANNOTATION.
STRAIN=cv. Columbia;
PubMed=27862469; DOI=10.1111/tpj.13415;
Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
Town C.D.;
"Araport11: a complete reannotation of the Arabidopsis thaliana
reference genome.";
Plant J. 89:789-804(2017).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
PubMed=14593172; DOI=10.1126/science.1088305;
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J.,
Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F.,
Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.,
Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J.,
Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y.,
Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P.,
Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F.,
Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M.,
Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J.,
Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T.,
Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y.,
Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis
genome.";
Science 302:842-846(2003).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
Hayashizaki Y., Shinozaki K.;
"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
[5]
FUNCTION, DISRUPTION PHENOTYPE, SUBCELLULAR LOCATION, DIMERIZATION,
AND INTERACTION WITH CASP2; CASP3; CASP4 AND CASP5.
STRAIN=cv. Columbia;
PubMed=21593871; DOI=10.1038/nature10070;
Roppolo D., De Rybel B., Denervaud Tendon V., Pfister A.,
Alassimone J., Vermeer J.E.M., Yamazaki M., Stierhof Y.-D.,
Beeckman T., Geldner N.;
"A novel protein family directs Casparian strip formation in the
endodermis.";
Nature 473:380-383(2011).
[6]
GENE FAMILY, NOMENCLATURE, SUBCELLULAR LOCATION, AND MUTAGENESIS OF
72-GLU--PHE-80; 73-THR--GLN-79; 74-LEU--THR-78; ASP-134; GLY-158;
158-GLY--CYS-175; TRP-164; CYS-168; GLN-170; PHE-174 AND CYS-175.
PubMed=24920445; DOI=10.1104/pp.114.239137;
Roppolo D., Boeckmann B., Pfister A., Boutet E., Rubio M.C.,
Denervaud-Tendon V., Vermeer J.E., Gheyselinck J., Xenarios I.,
Geldner N.;
"Functional and evolutionary analysis of the CASPARIAN STRIP MEMBRANE
DOMAIN PROTEIN family.";
Plant Physiol. 165:1709-1722(2014).
-!- FUNCTION: Regulates membrane-cell wall junctions and localized
cell wall deposition. Required for establishment of the Casparian
strip membrane domain (CSD) and the subsequent formation of
Casparian strips, a cell wall modification of the root endodermis
that determines an apoplastic barrier between the intraorganismal
apoplasm and the extraorganismal apoplasm and prevents lateral
diffusion. {ECO:0000269|PubMed:21593871}.
-!- SUBUNIT: Homodimer and heterodimers with other CASP proteins.
Interacts with CASP2, CASP3, CASP4 and CASP5.
{ECO:0000269|PubMed:21593871}.
-!- INTERACTION:
Q9ZQI2:CASP3; NbExp=2; IntAct=EBI-4451446, EBI-15927653;
-!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:21593871,
ECO:0000269|PubMed:24920445}; Multi-pass membrane protein
{ECO:0000269|PubMed:21593871, ECO:0000269|PubMed:24920445}.
Note=Very restricted localization following a belt shape within
the plasma membrane which coincides with the position of the
Casparian strip membrane domain.
-!- DISRUPTION PHENOTYPE: Disorganised deposition of Casparian strips.
{ECO:0000269|PubMed:21593871}.
-!- SIMILARITY: Belongs to the Casparian strip membrane proteins
(CASP) family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AC007135; AAD26967.1; -; Genomic_DNA.
EMBL; CP002685; AEC09206.1; -; Genomic_DNA.
EMBL; BT003113; AAO24545.1; -; mRNA.
EMBL; AK228127; BAF00084.1; -; mRNA.
PIR; H84776; H84776.
RefSeq; NP_181154.1; NM_129169.3.
UniGene; At.42995; -.
ProteinModelPortal; Q9SIH4; -.
BioGrid; 3527; 4.
DIP; DIP-59177N; -.
IntAct; Q9SIH4; 8.
STRING; 3702.AT2G36100.1; -.
iPTMnet; Q9SIH4; -.
PaxDb; Q9SIH4; -.
EnsemblPlants; AT2G36100.1; AT2G36100.1; AT2G36100.
GeneID; 818183; -.
Gramene; AT2G36100.1; AT2G36100.1; AT2G36100.
KEGG; ath:AT2G36100; -.
Araport; AT2G36100; -.
TAIR; locus:2053514; AT2G36100.
eggNOG; ENOG410IYVB; Eukaryota.
eggNOG; ENOG410YJEC; LUCA.
HOGENOM; HOG000237690; -.
InParanoid; Q9SIH4; -.
OMA; ANWLAFC; -.
OrthoDB; EOG09360W0R; -.
PhylomeDB; Q9SIH4; -.
PRO; PR:Q9SIH4; -.
Proteomes; UP000006548; Chromosome 2.
ExpressionAtlas; Q9SIH4; baseline and differential.
Genevisible; Q9SIH4; AT.
GO; GO:0048226; C:Casparian strip; IDA:UniProtKB.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO; GO:0051536; F:iron-sulfur cluster binding; IBA:GO_Central.
GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
GO; GO:0042545; P:cell wall modification; IMP:UniProtKB.
GO; GO:0007043; P:cell-cell junction assembly; IDA:UniProtKB.
InterPro; IPR006459; CASP/CASPL.
InterPro; IPR006702; CASP_dom.
Pfam; PF04535; DUF588; 1.
TIGRFAMs; TIGR01569; A_tha_TIGR01569; 1.
1: Evidence at protein level;
Acetylation; Cell membrane; Cell wall biogenesis/degradation;
Complete proteome; Glycoprotein; Membrane; Reference proteome;
Transmembrane; Transmembrane helix.
INIT_MET 1 1 Removed. {ECO:0000250|UniProtKB:Q9SQU2}.
CHAIN 2 206 Casparian strip membrane protein 1.
/FTId=PRO_0000308659.
TOPO_DOM 2 43 Cytoplasmic. {ECO:0000255}.
TRANSMEM 44 64 Helical. {ECO:0000255}.
TOPO_DOM 65 95 Extracellular. {ECO:0000255}.
TRANSMEM 96 116 Helical. {ECO:0000255}.
TOPO_DOM 117 127 Cytoplasmic. {ECO:0000255}.
TRANSMEM 128 148 Helical. {ECO:0000255}.
TOPO_DOM 149 180 Extracellular. {ECO:0000255}.
TRANSMEM 181 201 Helical. {ECO:0000255}.
TOPO_DOM 202 206 Cytoplasmic. {ECO:0000255}.
MOD_RES 2 2 N-acetylalanine.
{ECO:0000250|UniProtKB:Q9SQU2}.
CARBOHYD 159 159 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 177 177 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
MUTAGEN 72 80 Missing: Normal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 73 79 Missing: Normal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 74 78 Missing: Normal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 134 134 D->H: Not detectable probably due to an
impaired folding leading to instability.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 158 175 Missing: Normal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 158 158 G->S: Abnormal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 164 164 W->G: Abnormal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 168 168 C->S: Abnormal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 170 170 Q->E: Normal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 174 174 F->V: Abnormal subcellular localization.
{ECO:0000269|PubMed:24920445}.
MUTAGEN 175 175 C->S: Abnormal subcellular localization.
{ECO:0000269|PubMed:24920445}.
SEQUENCE 206 AA; 21970 MW; E0BCBE459A96C771 CRC64;
MAKESTTIDV GEPSTVTKSS SHVVKDAKKK GFVAVASRGG AKRGLAIFDF LLRLAAIAVT
IGAASVMYTA EETLPFFTQF LQFQAGYDDL PAFQYFVIAV AVVASYLVLS LPFSIVSIVR
PHAVAPRLIL LICDTLVVTL NTSAAAAAAS ITYLAHNGNQ STNWLPICQQ FGDFCQNVST
AVVADSIAIL FFIVLIIISA IALKRH


Related products :

Catalog number Product name Quantity
EIAAB07950 Acam,Adipocyte adhesion molecule,Asam,CAR-like membrane protein,Clmp,Coxsackie- and adenovirus receptor-like membrane protein,CXADR-like membrane protein,Rat,Rattus norvegicus
EIAAB07952 ACAM,Adipocyte adhesion molecule,ASAM,CAR-like membrane protein,CLMP,Coxsackie- and adenovirus receptor-like membrane protein,CXADR-like membrane protein,Homo sapiens,Human,UNQ318_PRO363
EIAAB07951 Acam,Adipocyte adhesion molecule,Adipocyte-specific protein 5,Asam,Asp5,CAR-like membrane protein,Clmp,Coxsackie- and adenovirus receptor-like membrane protein,CXADR-like membrane protein,Mouse,Mus mu
EIAAB37666 85 kDa lysosomal membrane sialoglycoprotein,LGP85,LIMP II,Lysosome membrane protein 2,Lysosome membrane protein II,Mouse,Mus musculus,Scarb2,Scavenger receptor class B member 2
EIAAB37665 85 kDa lysosomal membrane sialoglycoprotein,CD36 antigen-like 2,Cd36l2,LGP85,LIMP II,Limpii,Lysosome membrane protein 2,Lysosome membrane protein II,Rat,Rattus norvegicus,Scarb2,Scavenger receptor cla
EIAAB37664 85 kDa lysosomal membrane sialoglycoprotein,CD36 antigen-like 2,CD36L2,Homo sapiens,Human,LGP85,LIMP II,LIMPII,Lysosome membrane protein 2,Lysosome membrane protein II,SCARB2,Scavenger receptor class
EIAAB33227 28 kDa peroxisomal integral membrane protein,Peroxin-11A,Peroxisomal biogenesis factor 11A,Peroxisomal coatomer receptor,Peroxisomal membrane protein 11A,Peroxisomal membrane protein 26,Pex11,Pex11a,P
EIAAB12912 EMP1,EMP-1,Epithelial membrane protein 1,Oryctolagus cuniculus,Rabbit,Squamous cell-specific protein CL-20,Tumor-associated membrane protein
EIAAB29438 Homo sapiens,Human,Nuclear envelope pore membrane protein POM 121C,Nuclear pore membrane protein 121-2,POM121-2,POM121C,Pore membrane protein of 121 kDa C
EIAAB12918 EMP3,EMP-3,Epithelial membrane protein 3,Hematopoietic neural membrane protein 1,HNMP-1,Homo sapiens,Human,Protein YMP,YMP
EIAAB12917 Emp3,EMP-3,Epithelial membrane protein 3,Hematopoietic neural membrane protein 1,HNMP-1,Mouse,Mus musculus,Protein YMP,Ymp
EIAAB12909 B4B,CL-20,EMP1,EMP-1,Epithelial membrane protein 1,Homo sapiens,Human,Protein B4B,TMP,Tumor-associated membrane protein
2602.8.X Minitube System Strip Caps for 8 strip Mini tubes CS600 120 strips of 8/pk 5 pks/cs
3728.8AS.X 0.2 ml Strip tubes & caps 8 TUBECAP 8 STRIP 0.2ML CS1200 Assorted Sterile 120 strips/pk 10 pks/cs
2602.8S.X Minitube System Strip Caps for 8 strip Mini tubes_Sterile CS600 120 strips of 8/pk 5 pks/cs
27-403A .2ml 12_Well PCR Strip Tubes Strip Dome Caps Included 80 Strips/Unit
27-403A .2ml 12_Well PCR Strip Tubes Strip Dome Caps Included 80 Strips/Unit
27-403A .2ml 12_Well PCR Strip Tubes Strip Dome Caps Included 80 Strips/Unit
27-403A .2ml 12_Well PCR Strip Tubes Strip Dome Caps Included 80 Strips/Unit
27-403A .2ml 12_Well PCR Strip Tubes Strip Dome Caps Included 80 Strips/Unit
27-289 0.1ml 4-Strip Tubes & Strip Ca Corbett-type, Ultra Thin Wall Box of 250 Strips/Unit
R0115S PowerChekTM EHEC Real_time PCR strip Kit (stx1, stx2) 24 (8 strip X 3) 1 kit
3428.8A.X 0.2 ml Strip tubes & caps 8 TUBECAP 8 STRIP 0.2ML CS1200 Assorted 120 strips/pk 10 pks/cs
3728.8S.X 0.2 ml Strip tubes & caps 8 TUBECAP 8 STRIP 0.2ML CS1200 Sterile 120 strips/pk 10 pks/cs
27-403A .2ml 12_Well PCR Strip Tubes Strip Dome Caps Included 80 Strips/Unit


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur