Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cationic amino acid transporter 3 (CAT-3) (CAT3) (Cationic amino acid transporter y ) (Solute carrier family 7 member 3)

 CTR3_MOUSE              Reviewed;         618 AA.
P70423; B1AVE2;
16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
01-FEB-1997, sequence version 1.
05-DEC-2018, entry version 152.
RecName: Full=Cationic amino acid transporter 3;
Short=CAT-3;
Short=CAT3;
AltName: Full=Cationic amino acid transporter y+;
AltName: Full=Solute carrier family 7 member 3;
Name=Slc7a3; Synonyms=Atrc3, Cat3;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
TISSUE=Embryo;
PubMed=9334265; DOI=10.1074/jbc.272.42.26780;
Ito K., Groudine M.;
"A new member of the cationic amino acid transporter family is
preferentially expressed in adult mouse brain.";
J. Biol. Chem. 272:26780-26786(1997).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=C57BL/6J; TISSUE=Embryo;
PubMed=16141072; DOI=10.1126/science.1112014;
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M.,
Davis M.J., Wilming L.G., Aidinis V., Allen J.E.,
Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L.,
Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M.,
Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R.,
Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G.,
di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G.,
Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M.,
Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N.,
Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T.,
Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H.,
Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K.,
Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J.,
Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L.,
Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K.,
Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P.,
Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O.,
Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G.,
Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M.,
Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B.,
Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K.,
Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A.,
Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K.,
Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C.,
Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J.,
Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y.,
Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T.,
Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N.,
Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N.,
Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S.,
Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J.,
Hayashizaki Y.;
"The transcriptional landscape of the mammalian genome.";
Science 309:1559-1563(2005).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C57BL/6J;
PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S.,
She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W.,
Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T.,
Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J.,
Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z.,
Lindblad-Toh K., Eichler E.E., Ponting C.P.;
"Lineage-specific biology revealed by a finished genome assembly of
the mouse.";
PLoS Biol. 7:E1000112-E1000112(2009).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=129/Sv X 129/SvCp; TISSUE=Embryonic stem cell;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- FUNCTION: Mediates the uptake of the cationic amino acids
arginine, lysine and ornithine in a sodium-independent manner.
{ECO:0000269|PubMed:9334265}.
-!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
-!- TISSUE SPECIFICITY: Expressed in adult brain and in a wide variety
of embryonic tissues. {ECO:0000269|PubMed:9334265}.
-!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3)
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; U70859; AAB09593.1; -; mRNA.
EMBL; AK077593; BAC36884.1; -; mRNA.
EMBL; AL672308; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC050195; AAH50195.1; -; mRNA.
CCDS; CCDS30309.1; -.
RefSeq; NP_001288769.1; NM_001301840.1.
RefSeq; NP_031541.1; NM_007515.3.
RefSeq; XP_006527816.1; XM_006527753.2.
RefSeq; XP_011245812.1; XM_011247510.1.
RefSeq; XP_011245813.1; XM_011247511.1.
RefSeq; XP_011245814.1; XM_011247512.1.
RefSeq; XP_011245815.1; XM_011247513.1.
RefSeq; XP_017173852.1; XM_017318363.1.
RefSeq; XP_017173853.1; XM_017318364.1.
UniGene; Mm.5140; -.
ProteinModelPortal; P70423; -.
BioGrid; 198277; 1.
IntAct; P70423; 1.
STRING; 10090.ENSMUSP00000073582; -.
TCDB; 2.A.3.3.5; the amino acid-polyamine-organocation (apc) family.
iPTMnet; P70423; -.
PhosphoSitePlus; P70423; -.
SwissPalm; P70423; -.
EPD; P70423; -.
MaxQB; P70423; -.
PaxDb; P70423; -.
PeptideAtlas; P70423; -.
PRIDE; P70423; -.
Ensembl; ENSMUST00000073927; ENSMUSP00000073582; ENSMUSG00000031297.
Ensembl; ENSMUST00000101362; ENSMUSP00000098914; ENSMUSG00000031297.
Ensembl; ENSMUST00000113710; ENSMUSP00000109339; ENSMUSG00000031297.
GeneID; 11989; -.
KEGG; mmu:11989; -.
UCSC; uc009twt.2; mouse.
CTD; 84889; -.
MGI; MGI:1100521; Slc7a3.
eggNOG; KOG1286; Eukaryota.
eggNOG; COG0531; LUCA.
GeneTree; ENSGT00940000154651; -.
HOGENOM; HOG000250623; -.
HOVERGEN; HBG000280; -.
InParanoid; P70423; -.
KO; K13865; -.
OMA; FESIEWH; -.
OrthoDB; EOG091G05NM; -.
PhylomeDB; P70423; -.
TreeFam; TF315212; -.
Reactome; R-MMU-352230; Amino acid transport across the plasma membrane.
PRO; PR:P70423; -.
Proteomes; UP000000589; Chromosome X.
Bgee; ENSMUSG00000031297; Expressed in 117 organ(s), highest expression level in hypothalamus.
Genevisible; P70423; MM.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; ISO:MGI.
GO; GO:0015181; F:arginine transmembrane transporter activity; IDA:MGI.
GO; GO:0015174; F:basic amino acid transmembrane transporter activity; IDA:MGI.
GO; GO:0015189; F:L-lysine transmembrane transporter activity; IDA:MGI.
GO; GO:0000064; F:L-ornithine transmembrane transporter activity; ISO:MGI.
GO; GO:0015809; P:arginine transport; IDA:MGI.
GO; GO:0097638; P:L-arginine import across plasma membrane; IBA:GO_Central.
GO; GO:1903352; P:L-ornithine transmembrane transport; IBA:GO_Central.
GO; GO:0015819; P:lysine transport; ISO:MGI.
GO; GO:0015822; P:ornithine transport; ISO:MGI.
GO; GO:0032006; P:regulation of TOR signaling; ISO:MGI.
InterPro; IPR002293; AA/rel_permease1.
InterPro; IPR015606; CAT3.
InterPro; IPR004755; Cat_AA_permease.
InterPro; IPR029485; CAT_C.
PANTHER; PTHR43243:SF20; PTHR43243:SF20; 1.
Pfam; PF13520; AA_permease_2; 1.
Pfam; PF13906; AA_permease_C; 1.
PIRSF; PIRSF006060; AA_transporter; 1.
TIGRFAMs; TIGR00906; 2A0303; 1.
2: Evidence at transcript level;
Amino-acid transport; Cell membrane; Complete proteome; Glycoprotein;
Membrane; Phosphoprotein; Reference proteome; Transmembrane;
Transmembrane helix; Transport.
CHAIN 1 618 Cationic amino acid transporter 3.
/FTId=PRO_0000054267.
TOPO_DOM 1 36 Cytoplasmic. {ECO:0000255}.
TRANSMEM 37 57 Helical; Name=1. {ECO:0000255}.
TOPO_DOM 58 61 Extracellular. {ECO:0000255}.
TRANSMEM 62 82 Helical; Name=2. {ECO:0000255}.
TOPO_DOM 83 107 Cytoplasmic. {ECO:0000255}.
TRANSMEM 108 128 Helical; Name=3. {ECO:0000255}.
TOPO_DOM 129 162 Extracellular. {ECO:0000255}.
TRANSMEM 163 183 Helical; Name=4. {ECO:0000255}.
TOPO_DOM 184 191 Cytoplasmic. {ECO:0000255}.
TRANSMEM 192 212 Helical; Name=5. {ECO:0000255}.
TOPO_DOM 213 244 Extracellular. {ECO:0000255}.
TRANSMEM 245 265 Helical; Name=6. {ECO:0000255}.
TOPO_DOM 266 285 Cytoplasmic. {ECO:0000255}.
TRANSMEM 286 306 Helical; Name=7. {ECO:0000255}.
TOPO_DOM 307 335 Extracellular. {ECO:0000255}.
TRANSMEM 336 356 Helical; Name=8. {ECO:0000255}.
TOPO_DOM 357 380 Cytoplasmic. {ECO:0000255}.
TRANSMEM 381 401 Helical; Name=9. {ECO:0000255}.
TOPO_DOM 402 406 Extracellular. {ECO:0000255}.
TRANSMEM 407 427 Helical; Name=10. {ECO:0000255}.
TOPO_DOM 428 474 Cytoplasmic. {ECO:0000255}.
TRANSMEM 475 495 Helical; Name=11. {ECO:0000255}.
TOPO_DOM 496 506 Extracellular. {ECO:0000255}.
TRANSMEM 507 527 Helical; Name=12. {ECO:0000255}.
TOPO_DOM 528 539 Cytoplasmic. {ECO:0000255}.
TRANSMEM 540 560 Helical; Name=13. {ECO:0000255}.
TOPO_DOM 561 568 Extracellular. {ECO:0000255}.
TRANSMEM 569 589 Helical; Name=14. {ECO:0000255}.
TOPO_DOM 590 618 Cytoplasmic. {ECO:0000255}.
MOD_RES 605 605 Phosphothreonine.
{ECO:0000250|UniProtKB:Q8WY07}.
MOD_RES 617 617 Phosphoserine.
{ECO:0000250|UniProtKB:Q8WY07}.
CARBOHYD 232 232 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
SEQUENCE 618 AA; 67460 MW; 605AFC255A8251DC CRC64;
MLWQALRRFG QKLVRRRVLE LGMGETRLAR CLSTLDLVAL GVGSTLGAGV YVLAGEVAKD
KAGPSIVICF LVAALSSVLA GLCYAEFGAR VPGSGSAYLY SYVTVGELWA FTTGWNLILS
YVIGTASVAR AWSSAFDNLI GNHISRTLKG TILLKMPHVL AEYPDFFALA LVLLLTGLLV
LGASKSALVT KVFTGMNLLV LSFVIISGFI KGELRNWKLT KEDYCLTMSE SNGTCSLDSM
GSGGFMPFGL EGILRGAATC FYAFVGFDCI ATTGEEAQNP QRSIPMGIVI SMFICFLAYF
GVSSALTLMM PYYKLHPESP LPEAFSYVGW EPARYLVAIG SLCALSTSLL GSMFPMPRVM
YSMAEDGLLF RVLAKVHSVT HIPIVATLVS GVIAAFMAFL FELTDLVDLM SIGTLLAHSL
VSICVLILRY QPDQEMKSVE EEMELQEETL EAEKLTVQAL FCPVNSIPTL LSGRVVYVCS
SLLAVLLTVL CLVLTWWTTP LRSGDPVWVT VVVLILGLIL AISGVIWRQP QNRTPLHFKV
PAVPLLPLVS IFVNVYLMMQ MTAGTWARFG IWMLIGFAIY FGYGIQHSMK EVKNHQTLPK
TRAQTIDLDL TTSCVHSI


Related products :

Catalog number Product name Quantity
EIAAB09879 ATRC3,CAT3,CAT3,CAT-3,Cationic amino acid transporter 3,Cationic amino acid transporter y+,Homo sapiens,Human,SLC7A3,Solute carrier family 7 member 3
EIAAB09880 Atrc3,CAT3,Cat3,CAT-3,Cationic amino acid transporter 3,Cationic amino acid transporter y+,Rat,Rattus norvegicus,Slc7a3,Solute carrier family 7 member 3
EIAAB09881 Atrc3,CAT3,Cat3,CAT-3,Cationic amino acid transporter 3,Cationic amino acid transporter y+,Mouse,Mus musculus,Slc7a3,Solute carrier family 7 member 3
EIAAB46686 Cationic amino acid transporter, y+ system,Homo sapiens,Human,KIAA0245,SLC7A6,Solute carrier family 7 member 6,y(+)L-type amino acid transporter 2,Y+L amino acid transporter 2,Y+LAT2,y+LAT-2
201-20-5412 SLC7A1{solute carrier family 7 (cationic amino acid transporter, y+ system), member 1}rabbit.pAb 0.2ml
E1389054 Cat Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 2 (SLC7A2) ELISA Kit
Y105450 Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (Slc7a5), Human 50ug
Y105453 Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 11 (SLC7A11), Human 50ug
Y105451 Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (Slc7a5), Human 50ug
201-20-5413 SLC7A4{solute carrier family 7 (cationic amino acid transporter, y+ system), member 4}rabbit.pAb 0.2ml
201-20-5414 SLC7A5{solute carrier family 7 (cationic amino acid transporter, y+ system), member 5}rabbit.pAb 0.2ml
18-783-75522 RABBIT ANTI HUMAN CD98 LIGHT CHAIN (N-TERMINAL) - 4F2 LIGHT CHAIN; L-type amino acid transporter 1; Solute carrier family 7 member 5; y+ system cationic amino acid transporter; 4F2 light chain; 4F2 LC 0.05 mg
GWB-97FE81 Anti- SLC7A4 (solute carrier family 7 (cationic amino acid transporter. y+ system). member 4) Antibody
Y105451 Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (Slc7a5), Human Antibody 50ug
Y105450 Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (Slc7a5), Human Antibody 50ug
EIAAB09882 CAT4,CAT-4,Cationic amino acid transporter 4,Mouse,Mus musculus,Slc7a4,Solute carrier family 7 member 4
Y105453 Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 11 (SLC7A11), Human Antibody 50ug
EIAAB37161 Bos taurus,Bovine,Probable cationic amino acid transporter,SLC7A14,Solute carrier family 7 member 14
GWB-FB1D5B Anti- SLC7A14 (solute carrier family 7 (cationic amino acid transporter. y+ system). member 14) Antibody
GS-2062a solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 primary antibody, Host: Rabbit 200ul
EIAAB37159 Kiaa1613,Mouse,Mus musculus,Probable cationic amino acid transporter,Slc7a14,Solute carrier family 7 member 14
GWB-1D725E Anti- Solute Carrier Family 7 (Cationic Amino Acid Transporter Y+ System) Member 11 (SLC7A11) Human Antibody
EIAAB09883 CAT4,CAT-4,Cationic amino acid transporter 4,Homo sapiens,Human,SLC7A4,Solute carrier family 7 member 4
X2261P Human Solute Carrier Family 7 (Cationic Amino Acid Transporter) Member 5 Antigen Immunoaffinity Purified Polyclonal 50
EIAAB09878 ATRC2,CAT2,CAT-2,Low affinity cationic amino acid transporter 2,Pig,SLC7A2,Solute carrier family 7 member 2,Sus scrofa


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur