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Chalcone synthase-like protein 1 (EC 2.3.1.-)

 CHSL1_CANSA             Reviewed;         392 AA.
C6KI62;
06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
01-SEP-2009, sequence version 1.
22-NOV-2017, entry version 24.
RecName: Full=Chalcone synthase-like protein 1;
EC=2.3.1.-;
Name=CAN383;
Cannabis sativa (Hemp) (Marijuana).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; fabids; Rosales; Cannabaceae; Cannabis.
NCBI_TaxID=3483;
[1]
NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND TISSUE SPECIFICITY.
PubMed=19581347; DOI=10.1093/jxb/erp210;
Marks M.D., Tian L., Wenger J.P., Omburo S.N., Soto-Fuentes W., He J.,
Gang D.R., Weiblen G.D., Dixon R.A.;
"Identification of candidate genes affecting Delta9-
tetrahydrocannabinol biosynthesis in Cannabis sativa.";
J. Exp. Bot. 60:3715-3726(2009).
-!- FUNCTION: Chalcone synthase that may use malonyl-CoA and hexanoyl-
CoA as substrates but without producing olivetol or olivetolic
acid. {ECO:0000269|PubMed:19581347}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
-!- TISSUE SPECIFICITY: Expressed at the same level in leaves and in
glandular trichomes. {ECO:0000269|PubMed:19581347}.
-!- SIMILARITY: Belongs to the chalcone/stilbene synthases family.
{ECO:0000305}.
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EMBL; GQ222379; ACT10338.1; -; mRNA.
ProteinModelPortal; C6KI62; -.
SMR; C6KI62; -.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
Gene3D; 3.40.47.10; -; 2.
InterPro; IPR012328; Chalcone/stilbene_synth_C.
InterPro; IPR001099; Chalcone/stilbene_synthase_N.
InterPro; IPR011141; Polyketide_synthase_type-III.
InterPro; IPR016039; Thiolase-like.
PANTHER; PTHR11877; PTHR11877; 1.
Pfam; PF02797; Chal_sti_synt_C; 1.
Pfam; PF00195; Chal_sti_synt_N; 1.
PIRSF; PIRSF000451; PKS_III; 1.
SUPFAM; SSF53901; SSF53901; 2.
2: Evidence at transcript level;
Acyltransferase; Cytoplasm; Transferase.
CHAIN 1 392 Chalcone synthase-like protein 1.
/FTId=PRO_0000421154.
ACT_SITE 166 166 {ECO:0000250}.
SEQUENCE 392 AA; 43175 MW; 5F93F709224C084E CRC64;
MASISVDQIR KAQRANGPAT VLAIGTANPP TSFYQADYPD FYFRVTKNQH MTELKDKFKR
ICEKTTIKKR HLYLTEDRLN QHPNLLEYMA PSLNTRQDML VVEIPKLGKE AAMKAIKEWG
QPKSRITHLI FCSTNGVDMP GADYECAKLL GLSSSVKRVM LYQQGCHAGG SVLRIAKDLA
ENNKGARILT INSEITIGIF HSPDETYFDG MVGQALFGDG ASATIVGADP DKEIGERPVF
EMVSAAQEFI PNSDGAVDGH LTEAGLVYHI HKDVPGLISK NIEKSLVEAL NPIGISDWNS
LFWIVHPGGP AILNAVEAKL HLKKEKMADT RHVLSEYGNM SSVSIFFIMD KLRKRSLEEG
KSTTGDGFEW GVLFGFGPGL TVETIVLHSL AN


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