Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cholesteryl ester transfer protein (Lipid transfer protein I)

 CETP_MACFA              Reviewed;         493 AA.
P47896;
01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
01-FEB-1996, sequence version 1.
25-OCT-2017, entry version 63.
RecName: Full=Cholesteryl ester transfer protein {ECO:0000303|PubMed:1931878};
AltName: Full=Lipid transfer protein I {ECO:0000305};
Flags: Precursor;
Name=CETP {ECO:0000303|PubMed:1931878};
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
NCBI_TaxID=9541;
[1]
NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY,
AND INDUCTION.
PubMed=1931878;
Pape M.E., Rehberg E.F., Marotti K.R., Melchior G.W.;
"Molecular cloning, sequence, and expression of cynomolgus monkey
cholesteryl ester transfer protein. Inverse correlation between
hepatic cholesteryl ester transfer protein mRNA levels and plasma high
density lipoprotein levels.";
Arterioscler. Thromb. 11:1759-1771(1991).
[2]
FUNCTION, AND SUBCELLULAR LOCATION.
PubMed=24293641; DOI=10.1194/jlr.M043646;
Morton R.E., Izem L.;
"Cholesteryl ester transfer proteins from different species do not
have equivalent activities.";
J. Lipid Res. 55:258-265(2014).
-!- FUNCTION: Involved in the transfer of neutral lipids, including
cholesteryl ester and triglyceride, among lipoprotein particles.
Allows the net movement of cholesteryl ester from high density
lipoproteins/HDL to triglyceride-rich very low density
lipoproteins/VLDL, and the equimolar transport of triglyceride
from VLDL to HDL (PubMed:24293641). Regulates the reverse
cholesterol transport, by which excess cholesterol is removed from
peripheral tissues and returned to the liver for elimination (By
similarity). {ECO:0000250|UniProtKB:P11597,
ECO:0000269|PubMed:24293641}.
-!- SUBCELLULAR LOCATION: Secreted, extracellular space
{ECO:0000269|PubMed:24293641, ECO:0000303|PubMed:1931878}.
Note=Secreted in plasma. {ECO:0000303|PubMed:1931878}.
-!- TISSUE SPECIFICITY: Probably primarily expressed in liver and
adipose tissues. Detected in adrenal gland, mesenteric fat, spleen
and aorta. {ECO:0000269|PubMed:1931878}.
-!- INDUCTION: Up-regulated by high-fat, high-cholesterol diet.
{ECO:0000269|PubMed:1931878}.
-!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; M86343; AAA36840.1; -; mRNA.
PIR; A53176; A53176.
UniGene; Mfa.2826; -.
ProteinModelPortal; P47896; -.
SMR; P47896; -.
SwissLipids; SLP:000000486; -.
HOVERGEN; HBG005310; -.
GO; GO:0005615; C:extracellular space; IDA:UniProtKB.
GO; GO:0034364; C:high-density lipoprotein particle; IEA:InterPro.
GO; GO:0017127; F:cholesterol transporter activity; IDA:UniProtKB.
GO; GO:0008289; F:lipid binding; IEA:InterPro.
GO; GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.
GO; GO:0030301; P:cholesterol transport; IDA:UniProtKB.
GO; GO:0034375; P:high-density lipoprotein particle remodeling; IDA:UniProtKB.
GO; GO:0043691; P:reverse cholesterol transport; IEA:InterPro.
GO; GO:0034197; P:triglyceride transport; IDA:UniProtKB.
GO; GO:0034372; P:very-low-density lipoprotein particle remodeling; IDA:UniProtKB.
InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
InterPro; IPR032942; BPI/LBP/Plunc.
InterPro; IPR017130; Cholesteryl_ester_transfer.
InterPro; IPR001124; Lipid-bd_serum_glycop_C.
InterPro; IPR017954; Lipid-bd_serum_glycop_CS.
InterPro; IPR017942; Lipid-bd_serum_glycop_N.
PANTHER; PTHR10504; PTHR10504; 1.
PANTHER; PTHR10504:SF12; PTHR10504:SF12; 1.
Pfam; PF01273; LBP_BPI_CETP; 1.
Pfam; PF02886; LBP_BPI_CETP_C; 1.
PIRSF; PIRSF037185; Cholesteryl_ester_transf; 1.
SMART; SM00328; BPI1; 1.
SMART; SM00329; BPI2; 1.
SUPFAM; SSF55394; SSF55394; 2.
PROSITE; PS00400; LBP_BPI_CETP; 1.
2: Evidence at transcript level;
Cholesterol metabolism; Disulfide bond; Glycoprotein;
Lipid metabolism; Lipid transport; Secreted; Signal;
Steroid metabolism; Sterol metabolism; Transport.
SIGNAL 1 17 {ECO:0000250}.
CHAIN 18 493 Cholesteryl ester transfer protein.
/FTId=PRO_0000017156.
CARBOHYD 59 59 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 105 105 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 257 257 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 358 358 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 413 413 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 160 201 {ECO:0000250|UniProtKB:P11597}.
SEQUENCE 493 AA; 54743 MW; 7E82BE3C2A8FAE0D CRC64;
MLAATVLTLA LLGNVHACSK GTSHKAGIVC RITKPALLVL NQETAKVIQS AFQRANYPNI
TGEKAMMLLG QVKYGLHNIQ ISHLSIASSR VELVEAKSID VSIQNVSVVF KGTLKYGYTT
AWGLGIDQSV DFEIDSAIDL QINTQLTCDS GRVRTDAPDC YLSFHKLLLH LQGEREPGWI
KQLFTNFISF TLKLVLKGQI CKEINIISNI MADFVQTRAA SILSDGDIGV DISLTGDPII
TASYLESHHK GYFIYKNVSE DLPLPTFSPA LLGDSRMLYF WFSEQVFHSL AKVAFQDGRL
MLSLMGDEFK AVLETWGFNT NQEIFQEVVG GFPSQAQVTV HCLKMPRISC QNKGVVVNSS
VMVKFLFPRP DQQHSVAYTF EEDIMTTVQA SYSKKKLFLS LLDFQITPKT VSNLTESSSE
SVQSFLQSMI TTVGIPEVMS RLEAVFTALM NSKGLSLFDI INPEIITRDG FLLLQMDFGF
PEHLLVDFLQ SLS


Related products :

Catalog number Product name Quantity
010-21241 Anti CETP Human, Monoclonal Antibody (Clone No. CETP_4) Cholesteryl ester tranfer protein (CETP) is one of the lipid transfer proteins, which mediates the transfer of cholesteryl ester (CE), triglycer 100 UG
U0814h CLIA CETP,Cholesteryl ester transfer protein,Homo sapiens,Human,Lipid transfer protein I 96T
E0814h ELISA kit CETP,Cholesteryl ester transfer protein,Homo sapiens,Human,Lipid transfer protein I 96T
E0814Rb ELISA kit CETP,Cholesteryl ester transfer protein,Lipid transfer protein I,Oryctolagus cuniculus,Rabbit 96T
E0814h ELISA CETP,Cholesteryl ester transfer protein,Homo sapiens,Human,Lipid transfer protein I 96T
U0814Rb CLIA CETP,Cholesteryl ester transfer protein,Lipid transfer protein I,Oryctolagus cuniculus,Rabbit 96T
E0814Rb ELISA CETP,Cholesteryl ester transfer protein,Lipid transfer protein I,Oryctolagus cuniculus,Rabbit 96T
290-65401 Human CETP ELISA Kit Wako Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglyceri 72 tests
E02C0526 Rat Cholesteryl Ester Transfer Protein ELISA 96T/kit
EH1056 Cholesteryl ester transfer protein Elisa Kit 96T
E90814Hu ELISA Kit for Cholesteryl Ester Transfer Protein (CETP) 96T/Kit
E02C0526 Rat Cholesteryl Ester Transfer Protein ELISA , CETP
E12C0526 Chicken Cholesteryl Ester Transfer Protein ELISA 96T/kit
E02C0526 Rat Cholesteryl Ester Transfer Protein ELISA , CETP 96 Tests/kit
E05C0526 Guinea Pig Cholesteryl Ester Transfer Protein ELISA 96T/kit
ELI-6280 CETP Activity Kit (Cholesteryl ester transfer protein) 10 kits
E03C0526 Mouse Cholesteryl Ester Transfer Protein ELISA 96T/kit
E14C0526 Sheep Cholesteryl Ester Transfer Protein ELISA 96T/kit
E90814Rb ELISA Kit for Cholesteryl Ester Transfer Protein (CETP) 96T/Kit
E06C0526 Goat Cholesteryl Ester Transfer Protein ELISA 96T/kit
E02C0526 Rat Cholesteryl Ester Transfer Protein Elisa Kit (CETP) 96 Tests/kit
E11C0526 Bovine Cholesteryl Ester Transfer Protein ELISA 96T/kit
STA-614 Human Cholesteryl Ester Transfer Protein (CETP) ELISA Kit 96 assays
E04C0526 Rabbit Cholesteryl Ester Transfer Protein ELISA 96T/kit
E01C0526 Human Cholesteryl Ester Transfer Protein ELISA 96T/kit


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur