Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cholinergic receptor, nicotinic, beta 2 (Neuronal) (cDNA, FLJ94017, Homo sapiens cholinergic receptor, nicotinic, beta polypeptide 2(neuronal) (CHRNB2), mRNA)

 Q5SXY3_HUMAN            Unreviewed;       502 AA.
Q5SXY3;
10-MAY-2005, integrated into UniProtKB/TrEMBL.
10-MAY-2005, sequence version 1.
27-SEP-2017, entry version 119.
SubName: Full=Cholinergic receptor, nicotinic, beta 2 (Neuronal) {ECO:0000313|EMBL:EAW53192.1};
SubName: Full=cDNA, FLJ94017, Homo sapiens cholinergic receptor, nicotinic, beta polypeptide 2(neuronal) (CHRNB2), mRNA {ECO:0000313|EMBL:BAG36255.1};
Name=CHRNB2 {ECO:0000313|EMBL:EAW53192.1};
ORFNames=hCG_18732 {ECO:0000313|EMBL:EAW53192.1};
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG36255.1};
[1] {ECO:0000313|EMBL:EAW53192.1}
NUCLEOTIDE SEQUENCE.
PubMed=11181995; DOI=10.1126/science.1058040;
Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G.,
Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D.,
Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q.,
Kodira C.D., Zheng X.H., Chen L., Skupski M., Subramanian G.,
Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S.,
Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J.,
Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R.,
Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A.,
Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K.,
Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V.,
Brandon R., Cargill M., Chandramouliswaran I., Charlab R.,
Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K.,
Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z.,
Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A.,
Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V.,
Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B.,
Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J.,
Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C.,
Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L.,
Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S.,
Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A.,
Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D.,
Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L.,
Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N.,
Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S.,
Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F.,
Kline L., Koduru S., Love A., Mann F., May D., McCawley S.,
McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K.,
Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M.,
Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C.,
Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N.,
Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M.,
Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F.,
Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A.,
Mi H., Lazareva B., Hatton T., Narechania A., Diemer K.,
Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R.,
Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J.,
Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H.,
Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D.,
Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A.,
Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S.,
Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L.,
Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W.,
McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M.,
Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J.,
Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E.,
Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.;
"The sequence of the human genome.";
Science 291:1304-1351(2001).
[2] {ECO:0000313|EMBL:EAW53192.1}
NUCLEOTIDE SEQUENCE.
Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:BAG36255.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Hippocampus {ECO:0000313|EMBL:BAG36255.1};
Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y.,
Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R.,
Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N.,
Isogai T.;
"NEDO functional analysis of protein and research application
project.";
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
-!- SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell
membrane {ECO:0000256|SAAS:SAAS00548360}; Multi-pass membrane
protein {ECO:0000256|SAAS:SAAS00548360}.
-!- SUBCELLULAR LOCATION: Cell membrane
{ECO:0000256|SAAS:SAAS00548374}; Multi-pass membrane protein
{ECO:0000256|SAAS:SAAS00548374}.
-!- SIMILARITY: Belongs to the ligand-gated ion channel (TC 1.A.9)
family. {ECO:0000256|RuleBase:RU000687,
ECO:0000256|SAAS:SAAS00569405}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AK313470; BAG36255.1; -; mRNA.
EMBL; CH471121; EAW53192.1; -; Genomic_DNA.
RefSeq; NP_000739.1; NM_000748.2.
UniGene; Hs.2306; -.
SMR; Q5SXY3; -.
GeneID; 1141; -.
KEGG; hsa:1141; -.
UCSC; uc001ffg.4; human.
CTD; 1141; -.
EuPathDB; HostDB:ENSG00000160716.4; -.
PharmGKB; PA115; -.
eggNOG; KOG3645; Eukaryota.
eggNOG; ENOG410XQGR; LUCA.
HOVERGEN; HBG003756; -.
KO; K04813; -.
OrthoDB; EOG091G0R20; -.
ChiTaRS; CHRNB2; human.
GenomeRNAi; 1141; -.
Bgee; ENSG00000160716; -.
ExpressionAtlas; Q5SXY3; baseline and differential.
GO; GO:0005892; C:acetylcholine-gated channel complex; IEA:Ensembl.
GO; GO:0030054; C:cell junction; IEA:UniProtKB-KW.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0044853; C:plasma membrane raft; IEA:Ensembl.
GO; GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-SubCell.
GO; GO:0042166; F:acetylcholine binding; IEA:Ensembl.
GO; GO:0022848; F:acetylcholine-gated cation-selective channel activity; IEA:Ensembl.
GO; GO:0008144; F:drug binding; IEA:Ensembl.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0095500; P:acetylcholine receptor signaling pathway; IEA:Ensembl.
GO; GO:0001508; P:action potential; IEA:Ensembl.
GO; GO:0042113; P:B cell activation; IEA:Ensembl.
GO; GO:0035095; P:behavioral response to nicotine; IEA:Ensembl.
GO; GO:0006816; P:calcium ion transport; IEA:Ensembl.
GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IEA:Ensembl.
GO; GO:0001661; P:conditioned taste aversion; IEA:Ensembl.
GO; GO:0021771; P:lateral geniculate nucleus development; IEA:Ensembl.
GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
GO; GO:0051899; P:membrane depolarization; IEA:Ensembl.
GO; GO:0007613; P:memory; IEA:Ensembl.
GO; GO:0045759; P:negative regulation of action potential; IEA:Ensembl.
GO; GO:0021631; P:optic nerve morphogenesis; IEA:Ensembl.
GO; GO:0030890; P:positive regulation of B cell proliferation; IEA:Ensembl.
GO; GO:0033603; P:positive regulation of dopamine secretion; IEA:Ensembl.
GO; GO:0032226; P:positive regulation of synaptic transmission, dopaminergic; IEA:Ensembl.
GO; GO:0051291; P:protein heterooligomerization; IEA:Ensembl.
GO; GO:0045188; P:regulation of circadian sleep/wake cycle, non-REM sleep; IEA:Ensembl.
GO; GO:0042320; P:regulation of circadian sleep/wake cycle, REM sleep; IEA:Ensembl.
GO; GO:0048814; P:regulation of dendrite morphogenesis; IEA:Ensembl.
GO; GO:0042053; P:regulation of dopamine metabolic process; IEA:Ensembl.
GO; GO:0051963; P:regulation of synapse assembly; IEA:Ensembl.
GO; GO:0042220; P:response to cocaine; IEA:Ensembl.
GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
GO; GO:0001666; P:response to hypoxia; IEA:Ensembl.
GO; GO:0019233; P:sensory perception of pain; IEA:Ensembl.
GO; GO:0007605; P:sensory perception of sound; IEA:Ensembl.
GO; GO:0006939; P:smooth muscle contraction; IEA:Ensembl.
GO; GO:0035176; P:social behavior; IEA:Ensembl.
GO; GO:0060084; P:synaptic transmission involved in micturition; IEA:Ensembl.
GO; GO:0007271; P:synaptic transmission, cholinergic; IEA:Ensembl.
GO; GO:0021562; P:vestibulocochlear nerve development; IEA:Ensembl.
GO; GO:0008542; P:visual learning; IEA:Ensembl.
GO; GO:0007601; P:visual perception; IEA:Ensembl.
Gene3D; 2.70.170.10; -; 1.
InterPro; IPR032932; CHRNB2.
InterPro; IPR006202; Neur_chan_lig-bd.
InterPro; IPR006201; Neur_channel.
InterPro; IPR006029; Neurotrans-gated_channel_TM.
InterPro; IPR018000; Neurotransmitter_ion_chnl_CS.
InterPro; IPR002394; Nicotinic_acetylcholine_rcpt.
PANTHER; PTHR18945; PTHR18945; 1.
PANTHER; PTHR18945:SF730; PTHR18945:SF730; 1.
Pfam; PF02931; Neur_chan_LBD; 1.
Pfam; PF02932; Neur_chan_memb; 1.
PRINTS; PR00254; NICOTINICR.
PRINTS; PR00252; NRIONCHANNEL.
SUPFAM; SSF63712; SSF63712; 1.
SUPFAM; SSF90112; SSF90112; 1.
TIGRFAMs; TIGR00860; LIC; 1.
PROSITE; PS00236; NEUROTR_ION_CHANNEL; 1.
2: Evidence at transcript level;
Cell junction {ECO:0000256|SAAS:SAAS00032441};
Cell membrane {ECO:0000256|SAAS:SAAS00032539};
Disulfide bond {ECO:0000256|SAAS:SAAS00079022};
Ion channel {ECO:0000256|SAAS:SAAS00032596};
Ion transport {ECO:0000256|SAAS:SAAS00032596};
Ligand-gated ion channel {ECO:0000256|SAAS:SAAS00032596};
Membrane {ECO:0000256|SAAS:SAAS00032441,
ECO:0000256|SAAS:SAAS00032539, ECO:0000256|SAAS:SAAS00081645,
ECO:0000256|SAM:Phobius};
Postsynaptic cell membrane {ECO:0000256|SAAS:SAAS00032441};
Receptor {ECO:0000256|SAAS:SAAS00079193, ECO:0000313|EMBL:BAG36255.1};
Signal {ECO:0000256|SAM:SignalP};
Synapse {ECO:0000256|SAAS:SAAS00032441};
Transmembrane {ECO:0000256|SAAS:SAAS00081645,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00081645,
ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00032596}.
SIGNAL 1 25 {ECO:0000256|SAM:SignalP}.
CHAIN 26 502 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5010140446.
TRANSMEM 235 256 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 268 288 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 300 321 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 461 483 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 29 234 Neur_chan_LBD.
{ECO:0000259|Pfam:PF02931}.
DOMAIN 241 478 Neur_chan_memb.
{ECO:0000259|Pfam:PF02932}.
SEQUENCE 502 AA; 57019 MW; 7EEDEF6ADFDC9F23 CRC64;
MARRCGPVAL LLGFGLLRLC SGVWGTDTEE RLVEHLLDPS RYNKLIRPAT NGSELVTVQL
MVSLAQLISV HEREQIMTTN VWLTQEWEDY RLTWKPEEFD NMKKVRLPSK HIWLPDVVLY
NNADGMYEVS FYSNAVVSYD GSIFWLPPAI YKSACKIEVK HFPFDQQNCT MKFRSWTYDR
TEIDLVLKSE VASLDDFTPS GEWDIVALPG RRNENPDDST YVDITYDFII RRKPLFYTIN
LIIPCVLITS LAILVFYLPS DCGEKMTLCI SVLLALTVFL LLISKIVPPT SLDVPLVGKY
LMFTMVLVTF SIVTSVCVLN VHHRSPTTHT MAPWVKVVFL EKLPALLFMQ QPRHHCARQR
LRLRRRQRER EGAGALFFRE APGADSCTCF VNRASVQGLA GAFGAEPAPV AGPGRSGEPC
GCGLREAVDG VRFIADHMRS EDDDQSVSED WKYVAMVIDR LFLWIFVFVC VFGTIGMFLQ
PLFQNYTTTT FLHSDHSAPS SK


Related products :

Catalog number Product name Quantity
CHRNB4 CHRNB2 Gene cholinergic receptor, nicotinic, beta 2 (neuronal)
GWB-4CD785 Anti- CHRNB2 (cholinergic receptor. nicotinic. beta 2 (neuronal)) Antibody
GWB-C7968F Anti- CHRNB2 (cholinergic receptor. nicotinic. beta 2 (neuronal)) Antibody
GWB-6E62C4 Anti- CHRNB2 (cholinergic receptor. nicotinic. beta 2 (neuronal)) Antibody
GWB-AB066D Anti- CHRNB2 (cholinergic receptor. nicotinic. beta 2 (neuronal)) Antibody
CSB-EL005396RA Rat cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2) ELISA kit, Species Rat, Sample Type serum, plasma 96T
SEB513Hu ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 2 (CHRNb2) Homo sapiens (Human) 96T
E91513Hu ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 2 (CHRNb2) Organism: Homo sapiens (Human) 96T
E91513Hu ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 2 (CHRNb2) Organism Homo sapiens (Human) 96T
CSB-EL005396HU Human cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL005396MO Mouse cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
CSB-EL005396CH Chicken cholinergic receptor, nicotinic, beta 2 (neuronal) (CHRNB2) ELISA kit, Species Chicken, Sample Type serum, plasma 96T
DL-CHRNb2-Hu Human Cholinergic Receptor, Nicotinic, Beta 2 (CHRNb2) ELISA Kit 96T
201-12-3479 Human Cholinergic Receptor, Nicotinic, Beta 2(CHRNb2)ELISA Kit 96T
QY-E00571 Human Cholinergic Receptor, Nicotinic, Beta 2(CHRNb2)ELISA Kit 96T
UB-E00571 Human Cholinergic Receptor, Nicotinic, Beta 2(CHRNb2)ELISA Kit 96T
SED144Hu ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 3 (CHRNb3) Homo sapiens (Human) 96T
E93144Hu ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 3 (CHRNb3) Organism: Homo sapiens (Human) 96T
E91648Hu ELISA Kit for Cholinergic Receptor, Nicotinic, Beta 1 (CHRNb1) Organism Homo sapiens (Human) 96T
CHRNA4 CHRNA2 Gene cholinergic receptor, nicotinic, alpha 2 (neuronal)
CSB-EL005388RA Rat cholinergic receptor, nicotinic, alpha 2 (neuronal) (CHRNA2) ELISA kit, Species Rat, Sample Type serum, plasma 96T
CHRNB2 CHRNA9 Gene cholinergic receptor, nicotinic, alpha 9
31-095 CHRNB2 is a neuronal nicotinic acetylcholine receptor (nAChR) that belong to ligand-gated ion channels composed of alpha and beta subunits with specific structural, functional and pharmacological prop 0.05 mg
E10043h Human Cholinergic Receptor, Nicotinic, Beta 4 ELIS 96T
E9256h Human Cholinergic Receptor, Nicotinic, Beta 2 ELIS 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur