Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1)

 CLD3_HUMAN              Reviewed;         220 AA.
O15551;
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-JAN-1998, sequence version 1.
25-OCT-2017, entry version 146.
RecName: Full=Claudin-3;
AltName: Full=Clostridium perfringens enterotoxin receptor 2;
Short=CPE-R 2;
Short=CPE-receptor 2;
AltName: Full=Rat ventral prostate.1 protein homolog;
Short=hRVP1;
Name=CLDN3; Synonyms=C7orf1, CPETR2;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=9441748; DOI=10.1006/geno.1997.5033;
Peacock R.E., Keen T.J., Inglehearn C.F.;
"Analysis of a human gene homologous to rat ventral prostate.1
protein.";
Genomics 46:443-449(1997).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=9334247; DOI=10.1074/jbc.272.42.26652;
Katahira J., Sugiyama H., Inoue N., Horiguchi Y., Matsuda M.,
Sugimoto N.;
"Clostridium perfringens enterotoxin utilizes two structurally related
membrane proteins as functional receptors in vivo.";
J. Biol. Chem. 272:26652-26658(1997).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Colon;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[4]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-209, AND IDENTIFICATION
BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Liver;
PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
Wang L., Ye M., Zou H.;
"An enzyme assisted RP-RPLC approach for in-depth analysis of human
liver phosphoproteome.";
J. Proteomics 96:253-262(2014).
-!- FUNCTION: Plays a major role in tight junction-specific
obliteration of the intercellular space, through calcium-
independent cell-adhesion activity. {ECO:0000250}.
-!- SUBUNIT: Can form homo- and heteropolymers with other CLDN.
Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly
interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3 (By similarity).
{ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cell junction, tight junction {ECO:0000250}.
Cell membrane {ECO:0000250}; Multi-pass membrane protein
{ECO:0000250}.
-!- DISEASE: Note=CLDN3 is located in the Williams-Beuren syndrome
(WBS) critical region. WBS results from a hemizygous deletion of
several genes on chromosome 7q11.23, thought to arise as a
consequence of unequal crossing over between highly homologous
low-copy repeat sequences flanking the deleted region.
-!- SIMILARITY: Belongs to the claudin family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF007189; AAC78277.1; -; Genomic_DNA.
EMBL; AB000714; BAA22986.1; -; mRNA.
EMBL; BC016056; AAH16056.1; -; mRNA.
CCDS; CCDS5559.1; -.
RefSeq; NP_001297.1; NM_001306.3.
UniGene; Hs.647023; -.
ProteinModelPortal; O15551; -.
BioGrid; 107757; 4.
DIP; DIP-61079N; -.
IntAct; O15551; 1.
MINT; MINT-5003820; -.
STRING; 9606.ENSP00000378577; -.
TCDB; 1.H.1.1.15; the claudin tight junction (claudin1) family.
iPTMnet; O15551; -.
PhosphoSitePlus; O15551; -.
SwissPalm; O15551; -.
BioMuta; CLDN3; -.
EPD; O15551; -.
PaxDb; O15551; -.
PeptideAtlas; O15551; -.
PRIDE; O15551; -.
DNASU; 1365; -.
Ensembl; ENST00000395145; ENSP00000378577; ENSG00000165215.
GeneID; 1365; -.
KEGG; hsa:1365; -.
CTD; 1365; -.
DisGeNET; 1365; -.
EuPathDB; HostDB:ENSG00000165215.6; -.
GeneCards; CLDN3; -.
HGNC; HGNC:2045; CLDN3.
HPA; CAB002702; -.
HPA; HPA014361; -.
MIM; 602910; gene.
neXtProt; NX_O15551; -.
OpenTargets; ENSG00000165215; -.
PharmGKB; PA26571; -.
eggNOG; ENOG410IIJR; Eukaryota.
eggNOG; ENOG410YA61; LUCA.
GeneTree; ENSGT00760000118928; -.
HOGENOM; HOG000220937; -.
HOVERGEN; HBG000643; -.
InParanoid; O15551; -.
KO; K06087; -.
OMA; LCTIVCC; -.
OrthoDB; EOG091G0MMR; -.
PhylomeDB; O15551; -.
TreeFam; TF331936; -.
Reactome; R-HSA-420029; Tight junction interactions.
SIGNOR; O15551; -.
GeneWiki; CLDN3; -.
GenomeRNAi; 1365; -.
PRO; PR:O15551; -.
Proteomes; UP000005640; Chromosome 7.
Bgee; ENSG00000165215; -.
CleanEx; HS_CLDN3; -.
ExpressionAtlas; O15551; baseline and differential.
Genevisible; O15551; HS.
GO; GO:0016327; C:apicolateral plasma membrane; IEA:Ensembl.
GO; GO:0005923; C:bicellular tight junction; IDA:UniProtKB.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IDA:UniProtKB.
GO; GO:0016021; C:integral component of membrane; TAS:ProtInc.
GO; GO:0005887; C:integral component of plasma membrane; TAS:ProtInc.
GO; GO:0016328; C:lateral plasma membrane; IEA:Ensembl.
GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
GO; GO:0070830; P:bicellular tight junction assembly; IMP:UniProtKB.
GO; GO:0016338; P:calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; IEA:Ensembl.
GO; GO:0003382; P:epithelial cell morphogenesis; ISS:UniProtKB.
GO; GO:0051291; P:protein heterooligomerization; IGI:UniProtKB.
GO; GO:0051260; P:protein homooligomerization; IMP:UniProtKB.
GO; GO:0045471; P:response to ethanol; IEA:Ensembl.
GO; GO:0001666; P:response to hypoxia; IEP:UniProtKB.
InterPro; IPR006187; Claudin.
InterPro; IPR003549; Claudin3.
InterPro; IPR017974; Claudin_CS.
InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
PANTHER; PTHR12002; PTHR12002; 1.
Pfam; PF00822; PMP22_Claudin; 1.
PRINTS; PR01378; CLAUDIN3.
PROSITE; PS01346; CLAUDIN; 1.
1: Evidence at protein level;
Cell junction; Cell membrane; Complete proteome; Membrane;
Phosphoprotein; Reference proteome; Tight junction; Transmembrane;
Transmembrane helix; Williams-Beuren syndrome.
CHAIN 1 220 Claudin-3.
/FTId=PRO_0000144738.
TOPO_DOM 1 8 Cytoplasmic. {ECO:0000255}.
TRANSMEM 9 29 Helical. {ECO:0000255}.
TOPO_DOM 30 80 Extracellular. {ECO:0000255}.
TRANSMEM 81 101 Helical. {ECO:0000255}.
TOPO_DOM 102 115 Cytoplasmic. {ECO:0000255}.
TRANSMEM 116 136 Helical. {ECO:0000255}.
TOPO_DOM 137 159 Extracellular. {ECO:0000255}.
TRANSMEM 160 180 Helical. {ECO:0000255}.
TOPO_DOM 181 220 Cytoplasmic. {ECO:0000255}.
REGION 219 220 Interactions with TJP1, TJP2 and TJP3.
{ECO:0000250}.
MOD_RES 198 198 Phosphotyrosine.
{ECO:0000250|UniProtKB:Q9Z0G9}.
MOD_RES 199 199 Phosphoserine.
{ECO:0000250|UniProtKB:Q63400}.
MOD_RES 209 209 Phosphoserine.
{ECO:0000244|PubMed:24275569}.
SEQUENCE 220 AA; 23319 MW; 1C826EFFF1563C56 CRC64;
MSMGLEITGT ALAVLGWLGT IVCCALPMWR VSAFIGSNII TSQNIWEGLW MNCVVQSTGQ
MQCKVYDSLL ALPQDLQAAR ALIVVAILLA AFGLLVALVG AQCTNCVQDD TAKAKITIVA
GVLFLLAALL TLVPVSWSAN TIIRDFYNPV VPEAQKREMG AGLYVGWAAA ALQLLGGALL
CCSCPPREKK YTATKVVYSA PRSTGPGASL GTGYDRKDYV


Related products :

Catalog number Product name Quantity
EIAAB07851 C7orf1,Claudin-3,CLDN3,Clostridium perfringens enterotoxin receptor 2,CPE-R 2,CPE-receptor 2,CPETR2,Homo sapiens,hRVP1,Human,Rat ventral prostate.1 protein homolog
18-272-196247 Claudin 4 - Rabbit polyclonal to Claudin 4; Clostridium perfringens enterotoxin receptor; CPE-receptor; CPE-R; Williams-Beuren syndrome chromosome region 8 protein Polyclonal 0.5 ml
18-272-196248 Claudin 4 prediluted - Rabbit polyclonal to Claudin 4 prediluted; Clostridium perfringens enterotoxin receptor; CPE-receptor; CPE-R; Williams-Beuren syndrome chromosome region 8 protein Polyclonal 7 ml
EIAAB07854 Claudin-3,Cldn3,Clostridium perfringens enterotoxin receptor 2,CPE-R 2,CPE-receptor 2,Cpetr2,Mouse,Mus musculus
EIAAB07857 Claudin-4,Cldn4,Clostridium perfringens enterotoxin receptor,Cper,CPE-R,CPE-receptor,Cpetr1,Mouse,Mus musculus
EIAAB07856 Claudin-4,CLDN4,Clostridium perfringens enterotoxin receptor,CPER,CPE-R,CPE-receptor,CPETR1,Homo sapiens,Human,WBSCR8,Williams-Beuren syndrome chromosomal region 8 protein
2120-0130G RABBIT ANTI CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A, Product Type Polyclonal Antibody, Specificity CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A, Target Species Bacterial, Host Rabbit, Format Purified, Iso 1 ml
SCH-2120-0130G RABBIT ANTI CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A, Product Type Polyclonal Antibody, Specificity CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A, Target Species Bacterial, Host Rabbit, Format Purified, Iso 1 ml
EIAAB07852 Claudin-3,Cldn3,Rat,Rat ventral prostate.1 protein,Rattus norvegicus,RVP1
BP1016 Clostridium perfringens (Enterotoxin B) 0.5 ml
K254 Clostridium perfringens Enterotoxin 100
BP1016 Clostridium perfringens (Enterotoxin B) 0.5 ml
BP1016 Clostridium perfringens (Enterotoxin B) 0.5 ml
NB100-62475 Clostridium perfringens (Enterotoxin B) 0.5 ml
NB100-62475 Clostridium perfringens (Enterotoxin B) 0.5 ml
K254 Clostridium perfringens Enterotoxin conventional PCR 100 REACTIONS
YBG21200104 Clostridium perfringens Enterotoxin A, Rabbit anti_ 1 ml.
ABS8432 RABBIT ANTI CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A 1 ml
'BP1016 Clostridium perfringens (Enterotoxin B) antibody Ab host: Sheep 0.5 ml
'BP1016 Clostridium perfringens (Enterotoxin B) antibody Host Sheep 0.5 ml
GWB-1FACF9 RABBIT ANTI CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A Antibody
K254 Clostridium perfringens Enterotoxin, BACTERIA & PARASITES, conventional PCR 100 REACTIONS
YCC340-501 Clostridium perfringens Enterotoxin, Reversed Passive Latex Agglutination (RPLA) Kit kit
2120-0130G RABBIT ANTI CLOSTRIDIUM PERFRINGENS ENTEROTOXIN A-POLYCLONAL ANTIBODY 1 ml
EIAAB28493 D-GPCR,GPR164,G-protein coupled receptor 164,Homo sapiens,Human,Olfactory receptor 51E1,Olfactory receptor 52A3,OR51E1,OR51E1P,OR52A3P,POGR,Prostate-overexpressed G protein-coupled receptor,Prostate-s


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur