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Coatomer subunit delta (Delta-coat protein) (Delta-COP)

 COPD_SCHPO              Reviewed;         240 AA.
O74496;
05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
01-NOV-1998, sequence version 1.
22-NOV-2017, entry version 97.
RecName: Full=Coatomer subunit delta;
AltName: Full=Delta-coat protein;
Short=Delta-COP;
Name=ret2; ORFNames=SPCC285.08;
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
Schizosaccharomycetes; Schizosaccharomycetales;
Schizosaccharomycetaceae; Schizosaccharomyces.
NCBI_TaxID=284812;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=972 / ATCC 24843;
PubMed=11859360; DOI=10.1038/nature724;
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
-!- FUNCTION: The coatomer is a cytosolic protein complex that binds
to dilysine motifs and reversibly associates with Golgi non-
clathrin-coated vesicles, which further mediate biosynthetic
protein transport from the ER, via the Golgi up to the trans Golgi
network. Coatomer complex is required for budding from Golgi
membranes, and is essential for the retrograde Golgi-to-ER
transport of dilysine-tagged proteins (By similarity).
{ECO:0000250}.
-!- SUBUNIT: Oligomeric complex that consists of at least the alpha,
beta, beta', gamma, delta, epsilon and zeta subunits.
{ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
-!- SIMILARITY: Belongs to the adaptor complexes medium subunit
family. Delta-COP subfamily. {ECO:0000305}.
-----------------------------------------------------------------------
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EMBL; CU329672; CAA20847.1; -; Genomic_DNA.
PIR; T41254; T41254.
RefSeq; NP_588336.1; NM_001023327.2.
ProteinModelPortal; O74496; -.
SMR; O74496; -.
BioGrid; 275527; 3.
MINT; MINT-4679556; -.
STRING; 4896.SPCC285.08.1; -.
iPTMnet; O74496; -.
MaxQB; O74496; -.
PRIDE; O74496; -.
EnsemblFungi; SPCC285.08.1; SPCC285.08.1:pep; SPCC285.08.
GeneID; 2538953; -.
KEGG; spo:SPCC285.08; -.
EuPathDB; FungiDB:SPCC285.08; -.
PomBase; SPCC285.08; ret2.
InParanoid; O74496; -.
KO; K20471; -.
OMA; NSQHTTV; -.
OrthoDB; EOG092C50I9; -.
PhylomeDB; O74496; -.
Reactome; R-SPO-6807878; COPI-mediated anterograde transport.
Reactome; R-SPO-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
PRO; PR:O74496; -.
Proteomes; UP000002485; Chromosome III.
GO; GO:0030126; C:COPI vesicle coat; ISO:PomBase.
GO; GO:0005829; C:cytosol; IDA:PomBase.
GO; GO:0005634; C:nucleus; IDA:PomBase.
GO; GO:0006888; P:ER to Golgi vesicle-mediated transport; ISO:PomBase.
GO; GO:0006886; P:intracellular protein transport; IC:PomBase.
GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; ISO:PomBase.
InterPro; IPR022775; AP_mu_sigma_su.
InterPro; IPR027059; Coatomer_dsu.
InterPro; IPR011012; Longin-like_dom_sf.
PANTHER; PTHR10121; PTHR10121; 1.
Pfam; PF01217; Clat_adaptor_s; 1.
SUPFAM; SSF64356; SSF64356; 1.
3: Inferred from homology;
Complete proteome; Cytoplasm; Nucleus; Protein transport;
Reference proteome; Transport.
CHAIN 1 240 Coatomer subunit delta.
/FTId=PRO_0000316200.
SEQUENCE 240 AA; 27098 MW; 4FE4F18AD1266664 CRC64;
MVVLAVSIVN RGGKAIISRQ FREMSRVRVE SLLSSFPALV SEKSQNTTVE SDNVRFVYQP
LDELYIVLIT NLQSNILQDI DTLHLLSQVV TSICSSLEER EILEYAFEIF TAFDEATSLG
YRDNVSLTQI KTYLEMESHE EKIQEIVSRN KEIEATEERK RRIKQLELQK KEAARRAAQN
LPSADAYESI GYQTVNTTFA TSNVEDESAM ESYHAAAKAS SAPKAKGMQL GKKKNTSLLY


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