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Coxsackievirus and adenovirus receptor homolog

 H2P2S8_PONAB            Unreviewed;       365 AA.
H2P2S8;
21-MAR-2012, integrated into UniProtKB/TrEMBL.
21-MAR-2012, sequence version 1.
25-OCT-2017, entry version 36.
SubName: Full=Coxsackievirus and adenovirus receptor homolog {ECO:0000313|Ensembl:ENSPPYP00000012617};
Name=CXADR {ECO:0000313|Ensembl:ENSPPYP00000012617};
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Pongo.
NCBI_TaxID=9601 {ECO:0000313|Ensembl:ENSPPYP00000012617, ECO:0000313|Proteomes:UP000001595};
[1] {ECO:0000313|Ensembl:ENSPPYP00000012617, ECO:0000313|Proteomes:UP000001595}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Wilson R.K., Mardis E.;
"A 6x draft sequence assembly of the Pongo pygmaeus abelii genome.";
Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSPPYP00000012617}
IDENTIFICATION.
Ensembl;
Submitted (FEB-2012) to UniProtKB.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSPPYP00000012617}.
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EMBL; ABGA01170838; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01170839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01170840; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01170841; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01170842; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; ABGA01170843; -; NOT_ANNOTATED_CDS; Genomic_DNA.
Ensembl; ENSPPYT00000013117; ENSPPYP00000012617; ENSPPYG00000011295.
eggNOG; ENOG410IGDG; Eukaryota.
eggNOG; ENOG4110WP1; LUCA.
GeneTree; ENSGT00760000119145; -.
InParanoid; H2P2S8; -.
OMA; VGNKKIQ; -.
OrthoDB; EOG091G05PI; -.
TreeFam; TF330875; -.
Proteomes; UP000001595; Chromosome 21.
GO; GO:0016327; C:apicolateral plasma membrane; IEA:Ensembl.
GO; GO:0016323; C:basolateral plasma membrane; IEA:Ensembl.
GO; GO:0005923; C:bicellular tight junction; IEA:Ensembl.
GO; GO:0005913; C:cell-cell adherens junction; IEA:Ensembl.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0045121; C:membrane raft; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0043234; C:protein complex; IEA:Ensembl.
GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
GO; GO:0005178; F:integrin binding; IEA:Ensembl.
GO; GO:0030165; F:PDZ domain binding; IEA:Ensembl.
GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
GO; GO:0010669; P:epithelial structure maintenance; IEA:Ensembl.
GO; GO:0007157; P:heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; IEA:Ensembl.
GO; GO:0030593; P:neutrophil chemotaxis; IEA:Ensembl.
GO; GO:0070633; P:transepithelial transport; IEA:Ensembl.
Gene3D; 1.20.5.100; -; 1.
Gene3D; 2.60.40.10; -; 2.
InterPro; IPR021157; Cyt_c1_TM_anchor_C.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR013106; Ig_V-set.
InterPro; IPR013151; Immunoglobulin.
Pfam; PF00047; ig; 1.
Pfam; PF07686; V-set; 1.
SMART; SM00409; IG; 2.
SMART; SM00408; IGc2; 2.
SMART; SM00406; IGv; 1.
SUPFAM; SSF48726; SSF48726; 2.
PROSITE; PS50835; IG_LIKE; 2.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000001595};
Disulfide bond {ECO:0000256|SAAS:SAAS00909350};
Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
Membrane {ECO:0000256|SAAS:SAAS00907743, ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000001595};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAAS:SAAS00907743,
ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00907743,
ECO:0000256|SAM:Phobius}.
SIGNAL 1 19 {ECO:0000256|SAM:SignalP}.
CHAIN 20 365 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5003566683.
TRANSMEM 236 260 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 18 134 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 141 228 Ig-like. {ECO:0000259|PROSITE:PS50835}.
SEQUENCE 365 AA; 40081 MW; 767FC11593CD1479 CRC64;
MALLLRFVLL CGVADFARSL SITTPEEMIE KAKGETAYLP CKFTLSPEDQ GPLDIEWLIS
PADNQKVDQV IILYSGDKIY DDYYPDLKGR VHFTSNDLKS GDASINVTNL QLSDIGTYQC
KVKKAPGVAN KKIHLVVLVK PSGARCYVDG SEEIGSDFKL KCEPKEGSLP LQYEWQKLSD
SQKMPTLWLA EMTSSVISVK NASSEYSGTY SCTVRNRVGS DQCLLRLNVV PPSNKAGLIA
GAIIGTLLAL ALIGLIIFCC RKKRREEKYE KEVHHDIRED VPPPKSRTST ARSYIGSNHS
SLGSMSPSNM EGYSKTQYNQ VPSEDFERTP QSPTLPPAKV AAPNLSRMGA IPVMIPAQSK
DGSIV


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