Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3) (Liver regeneration factor 1) (LRF-1)

 ATF3_RAT                Reviewed;         181 AA.
P29596;
01-APR-1993, integrated into UniProtKB/Swiss-Prot.
01-APR-1993, sequence version 1.
30-AUG-2017, entry version 129.
RecName: Full=Cyclic AMP-dependent transcription factor ATF-3;
Short=cAMP-dependent transcription factor ATF-3;
AltName: Full=Activating transcription factor 3;
AltName: Full=Liver regeneration factor 1;
Short=LRF-1;
Name=Atf3; Synonyms=Lrf1;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Fischer; TISSUE=Liver;
PubMed=1902565; DOI=10.1073/pnas.88.9.3511;
Hsu J.-C., Laz T., Mohn K.L., Taub R.;
"Identification of LRF-1, a leucine-zipper protein that is rapidly and
highly induced in regenerating liver.";
Proc. Natl. Acad. Sci. U.S.A. 88:3511-3515(1991).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Lung;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- FUNCTION: In solution, it binds the cAMP response element (CRE)
(consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many
viral and cellular promoters but also has affinity for related
sites. May have a unique and critical role in growth regulation of
regenerating liver and mitogen-stimulated cells.
-!- SUBUNIT: ATF3 alone can bind DNA, but it preferentially forms
heteromeric complexes with JUN and JUNB and does not interact with
FOS.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-
ProRule:PRU00978}.
-!- TISSUE SPECIFICITY: In tissues containing skeletal muscle or
smooth muscle, and at low levels in some tumor cells.
-!- INDUCTION: Rapidly and highly induced in regenerating liver and
mitogen-stimulated cells.
-!- SIMILARITY: Belongs to the bZIP family. ATF subfamily.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; M63282; AAA41542.1; -; mRNA.
EMBL; BC078903; AAH78903.1; -; mRNA.
PIR; A39382; A39382.
RefSeq; NP_037044.1; NM_012912.2.
UniGene; Rn.9664; -.
ProteinModelPortal; P29596; -.
SMR; P29596; -.
STRING; 10116.ENSRNOP00000005085; -.
PaxDb; P29596; -.
Ensembl; ENSRNOT00000005085; ENSRNOP00000005085; ENSRNOG00000003745.
Ensembl; ENSRNOT00000089841; ENSRNOP00000071188; ENSRNOG00000003745.
GeneID; 25389; -.
KEGG; rno:25389; -.
CTD; 467; -.
RGD; 2165; Atf3.
eggNOG; KOG1414; Eukaryota.
eggNOG; ENOG4111CH5; LUCA.
GeneTree; ENSGT00730000110847; -.
HOGENOM; HOG000034126; -.
HOVERGEN; HBG003381; -.
InParanoid; P29596; -.
KO; K09032; -.
OMA; LVYMLNL; -.
OrthoDB; EOG091G0M4N; -.
PhylomeDB; P29596; -.
TreeFam; TF326301; -.
PRO; PR:P29596; -.
Proteomes; UP000002494; Chromosome 13.
Bgee; ENSRNOG00000003745; -.
Genevisible; P29596; RN.
GO; GO:1990622; C:CHOP-ATF3 complex; IEA:Ensembl.
GO; GO:0005730; C:nucleolus; IEA:Ensembl.
GO; GO:0046982; F:protein heterodimerization activity; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:Ensembl.
GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; TAS:RGD.
GO; GO:0001078; F:transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding; IEA:Ensembl.
GO; GO:0001709; P:cell fate determination; TAS:RGD.
GO; GO:0034198; P:cellular response to amino acid starvation; IEA:Ensembl.
GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IEA:Ensembl.
GO; GO:0006094; P:gluconeogenesis; IEA:Ensembl.
GO; GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
GO; GO:0008284; P:positive regulation of cell proliferation; IMP:RGD.
GO; GO:1903984; P:positive regulation of TRAIL-activated apoptotic signaling pathway; IEA:Ensembl.
GO; GO:1990440; P:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress; IEA:Ensembl.
GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
InterPro; IPR000837; AP-1.
InterPro; IPR029812; ATF3.
InterPro; IPR004827; bZIP.
PANTHER; PTHR23351; PTHR23351; 1.
PANTHER; PTHR23351:SF39; PTHR23351:SF39; 1.
Pfam; PF00170; bZIP_1; 1.
PRINTS; PR00042; LEUZIPPRFOS.
SMART; SM00338; BRLZ; 1.
PROSITE; PS50217; BZIP; 1.
PROSITE; PS00036; BZIP_BASIC; 1.
2: Evidence at transcript level;
Complete proteome; DNA-binding; Isopeptide bond; Nucleus;
Phosphoprotein; Reference proteome; Repressor; Transcription;
Transcription regulation; Ubl conjugation.
CHAIN 1 181 Cyclic AMP-dependent transcription factor
ATF-3.
/FTId=PRO_0000076583.
DOMAIN 86 149 bZIP. {ECO:0000255|PROSITE-
ProRule:PRU00978}.
REGION 88 110 Basic motif. {ECO:0000255|PROSITE-
ProRule:PRU00978}.
REGION 114 142 Leucine-zipper. {ECO:0000255|PROSITE-
ProRule:PRU00978}.
MOD_RES 162 162 Phosphothreonine.
{ECO:0000250|UniProtKB:P18847}.
CROSSLNK 78 78 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in SUMO2).
{ECO:0000250|UniProtKB:P18847}.
CROSSLNK 175 175 Glycyl lysine isopeptide (Lys-Gly)
(interchain with G-Cter in SUMO2).
{ECO:0000250|UniProtKB:P18847}.
SEQUENCE 181 AA; 20764 MW; E36971E1A96F262B CRC64;
MMLQHPGQVS ASEVSATAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ NKHLCHRMSS
ALESVTINNR PLEMSVTKSE VAPEEDERKR RRRERNKIAA AKCRNKKKEK TECLQKESEK
LESVNAELKA QIEELKNEKQ HLIYMLNLHR PTCIVRAQNG RTPEDERNLF IQQIKEGTLQ
S


Related products :

Catalog number Product name Quantity
U1346h CLIA Activating transcription factor 1,ATF1,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1,Homo sapiens,Human,Protein TREB36 96T
E1346h ELISA kit Activating transcription factor 1,ATF1,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1,Homo sapiens,Human,Protein TREB36 96T
E1346h ELISA Activating transcription factor 1,ATF1,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1,Homo sapiens,Human,Protein TREB36 96T
E1346b ELISA kit Activating transcription factor 1,ATF1,Bos taurus,Bovine,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1 96T
U1346b CLIA Activating transcription factor 1,ATF1,Bos taurus,Bovine,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1 96T
E1346b ELISA Activating transcription factor 1,ATF1,Bos taurus,Bovine,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1 96T
U1346m CLIA Activating transcription factor 1,Atf1,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1,Mouse,Mus musculus,TCR-ATF1 96T
E1346m ELISA Activating transcription factor 1,Atf1,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1,Mouse,Mus musculus,TCR-ATF1 96T
E1346m ELISA kit Activating transcription factor 1,Atf1,cAMP-dependent transcription factor ATF-1,Cyclic AMP-dependent transcription factor ATF-1,Mouse,Mus musculus,TCR-ATF1 96T
10-782-55004 Cyclic AMP-dependent transcription factor ATF-2 - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 N_A 0.2 mg
10-782-55004 Cyclic AMP-dependent transcription factor ATF-2 - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 N_A 0.05 mg
18-003-42489 Cyclic AMP-dependent transcription factor ATF-2 - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 Polyclonal 0.1 mg Protein A
18-662-20064 Cyclic AMP-dependent transcription factor ATF-2 - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 Polyclonal 0.1 ml
18-003-42999 Cyclic AMP-dependent transcription factor ATF-5 - Activating transcription factor 5; Transcription factor ATFx Polyclonal 0.05 mg Aff Pur
18-003-43256 Cyclic AMP-dependent transcription factor ATF-7 - Activating transcription factor 7; Transcription factor ATF-A Polyclonal 0.1 mg Protein A
18-003-43222 Cyclic AMP-dependent transcription factor ATF-1 - Activating transcription factor 1; TREB36 protein Polyclonal 0.05 mg Aff Pur
18-003-44064 Cyclic AMP-dependent transcription factor ATF-4 - Activating transcription factor 4; DNA-binding protein TAXREB67; Cyclic AMP response element-binding protein 2; CREB2 Polyclonal 0.1 mg Protein A
27-359 TCFL5 is a new bHLH transcription factor that negatively regulates upstream transcription factor-dependent transcription. 0.05 mg
10-663-45549 Activating Transcription Factor-2 (ATF-2) Human - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 N_A 0.01 mg
10-663-45549 Activating Transcription Factor-2 (ATF-2) Human - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 N_A 0.002 mg
10-663-45549 Activating Transcription Factor-2 (ATF-2) Human - Activating transcription factor 2; cAMP response element-binding protein CRE-BP1; HB16 N_A 1 mg
EIAAB41105 ATP-dependent helicase GTF2F2,General transcription factor IIF 30 kDa subunit,General transcription factor IIF subunit 2,GTF2F2,Homo sapiens,Human,RAP30,TFIIF-beta,Transcription initiation factor IIF
EIAAB42103 Immunoglobulin enhancer-binding factor E12_E47,Pan,Pancreas specific transcription factor 1c,Ptf1c,Rat,Rattus norvegicus,Tcf3,TCF-3,Tcfe2a,Transcription factor 3,Transcription factor E2-alpha,Transcri
18-003-42098 Ets domain transcription factor - ESE3 transcription factor; EHF protein; DJ875K15.1.2 (Ets homologous factor (Ets-domain transcription factor. ESE-3B (Isoform 2))); ETS-family transcription factor EH 0.1 mg Protein A
EIAAB42104 Alf2,Immunoglobulin enhancer-binding factor E12_E47,Me2,Mouse,Mus musculus,Tcf3,TCF-3,Tcfe2a,Transcription factor 3,Transcription factor A1,Transcription factor E2-alpha


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur