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Cyclin-dependent kinase catalytic subunit (Transferase (Phosphotransferase) domain 1)

 F2QZF7_KOMPC            Unreviewed;       322 AA.
F2QZF7;
31-MAY-2011, integrated into UniProtKB/TrEMBL.
31-MAY-2011, sequence version 1.
23-MAY-2018, entry version 47.
SubName: Full=Cyclin-dependent kinase catalytic subunit {ECO:0000313|EMBL:CCA40785.1};
Name=CDC28 {ECO:0000313|EMBL:CCA40785.1};
OrderedLocusNames=PP7435_Chr4-0625 {ECO:0000313|EMBL:CCA40785.1};
Komagataella phaffii (strain ATCC 76273 / CBS 7435 / CECT 11047 / NRRL
Y-11430 / Wegner 21-1) (Yeast) (Pichia pastoris).
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Phaffomycetaceae; Komagataella.
NCBI_TaxID=981350 {ECO:0000313|EMBL:CCA40785.1, ECO:0000313|Proteomes:UP000006853};
[1] {ECO:0000313|EMBL:CCA40785.1, ECO:0000313|Proteomes:UP000006853}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1
{ECO:0000313|Proteomes:UP000006853};
PubMed=21575661; DOI=10.1016/j.jbiotec.2011.04.014;
Kuberl A., Schneider J., Thallinger G.G., Anderl I., Wibberg D.,
Hajek T., Jaenicke S., Brinkrolf K., Goesmann A., Szczepanowski R.,
Puhler A., Schwab H., Glieder A., Pichler H.;
"High-quality genome sequence of Pichia pastoris CBS7435.";
J. Biotechnol. 154:312-320(2011).
[2]
NUCLEOTIDE SEQUENCE.
STRAIN=CBS 7435;
Kueberl A., Schneider J., Thallinger G.G., Anderl I., Wibberg D.,
Hajek T., Jaenicke S., Brinkrolf K., Goesmann A., Szczepanowski R.,
Puehler A., Schwab H., Glieder A., Pichler H.;
"High-quality genome sequence of Pichia pastoris CBS 7435.";
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Proteomes:UP000006853}
GENOME REANNOTATION.
STRAIN=ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner 21-1
{ECO:0000313|Proteomes:UP000006853};
PubMed=27388471; DOI=10.1093/femsyr/fow051;
Valli M., Tatto N.E., Peymann A., Gruber C., Landes N., Ekker H.,
Thallinger G.G., Mattanovich D., Gasser B., Graf A.B.;
"Curation of the genome annotation of Pichia pastoris (Komagataella
phaffii) CBS7435 from gene level to protein function.";
FEMS Yeast Res. 16:0-0(2016).
-!- SIMILARITY: Belongs to the protein kinase superfamily.
{ECO:0000256|RuleBase:RU000304}.
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EMBL; FR839631; CCA40785.1; -; Genomic_DNA.
ProteinModelPortal; F2QZF7; -.
SMR; F2QZF7; -.
EnsemblFungi; CCA40785; CCA40785; PP7435_CHR4-0625.
OrthoDB; EOG092C2FL8; -.
Proteomes; UP000006853; Chromosome 4.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
InterPro; IPR011009; Kinase-like_dom_sf.
InterPro; IPR000719; Prot_kinase_dom.
InterPro; IPR017441; Protein_kinase_ATP_BS.
InterPro; IPR008271; Ser/Thr_kinase_AS.
Pfam; PF00069; Pkinase; 1.
SMART; SM00220; S_TKc; 1.
SUPFAM; SSF56112; SSF56112; 1.
PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|RuleBase:RU000304};
Complete proteome {ECO:0000313|Proteomes:UP000006853};
Kinase {ECO:0000256|RuleBase:RU000304};
Nucleotide-binding {ECO:0000256|RuleBase:RU000304};
Serine/threonine-protein kinase {ECO:0000256|RuleBase:RU000304};
Transferase {ECO:0000256|RuleBase:RU000304}.
SEQUENCE 322 AA; 36690 MW; 273AD85198B7B6D4 CRC64;
MGELADYQRL EKIGEGTYGV VYKALDIRHN NRVVALKKIR LESEDEGVPS TAIREISLLK
ELKDDNIVRL YDIVHSDSHK LYLVFEFLDL DFKKYMESIP QGAGLGAAMV KRFMIQLIRG
ILYCHSHRIL HRDLKPQNLL IDKEGNLKLA DFGLARAFGV PLRAYTHEVV TLWYRAPEIL
LGGKQYSTGV DMWSIGCIFA EMVNRKPLFA GDSEIDQIFR IFRVLGTPNE ENWPEVNYLP
DFKPTFPKWG RKSLASVVTS LDADGIDLLE RLLVYDPAGR ISAKRALQHS YFFDDAITAP
LTDADHELHQ SNMQVDTSAV YT


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