Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cystine transporter (ERD suppressor) (Transmembrane protein ERS1)

 ERS1_YEAST              Reviewed;         260 AA.
P17261; D6VR77;
01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
01-AUG-1990, sequence version 1.
18-JUL-2018, entry version 143.
RecName: Full=Cystine transporter;
AltName: Full=ERD suppressor;
AltName: Full=Transmembrane protein ERS1;
Name=ERS1; OrderedLocusNames=YCR075C; ORFNames=YCR75C;
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
PubMed=2186379; DOI=10.1093/nar/18.8.2177;
Hardwick K., Pelham H.;
"ERS1 a seven transmembrane domain protein from Saccharomyces
Nucleic Acids Res. 18:2177-2177(1990).
STRAIN=ATCC 204508 / S288c;
PubMed=1574125; DOI=10.1038/357038a0;
Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M.,
Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W.,
Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H.,
Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V.,
Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A.,
de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H.,
Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K.,
Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B.,
Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A.,
Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y.,
Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R.,
Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G.,
Tzermia M., Urrestarazu L.A., Valle G., Vetter I.,
van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H.,
Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C.,
Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.;
"The complete DNA sequence of yeast chromosome III.";
Nature 357:38-46(1992).
STRAIN=ATCC 204508 / S288c;
PubMed=24374639; DOI=10.1534/g3.113.008995;
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M.,
Cherry J.M.;
"The reference genome sequence of Saccharomyces cerevisiae: Then and
G3 (Bethesda) 4:389-398(2014).
PubMed=15885099; DOI=10.1111/j.1742-4658.2005.04670.x;
Gao X.-D., Wang J., Keppler-Ross S., Dean N.;
"ERS1 encodes a functional homologue of the human lysosomal cystine
FEBS J. 272:2497-2511(2005).
-!- FUNCTION: Transport cystine out of vacuoles/endodomes.
-!- SUBCELLULAR LOCATION: Endosome membrane
{ECO:0000269|PubMed:15885099}; Multi-pass membrane protein
{ECO:0000269|PubMed:15885099}. Vacuole membrane
{ECO:0000269|PubMed:15885099}; Multi-pass membrane protein
-!- SIMILARITY: Belongs to the cystinosin family. {ECO:0000305}.
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
EMBL; X52468; CAA36706.1; -; Genomic_DNA.
EMBL; X59720; CAA42264.1; -; Genomic_DNA.
EMBL; BK006937; DAA07546.1; -; Genomic_DNA.
PIR; S22850; S22850.
RefSeq; NP_010000.1; NM_001178784.1.
ProteinModelPortal; P17261; -.
BioGrid; 31050; 139.
DIP; DIP-8250N; -.
IntAct; P17261; 4.
MINT; P17261; -.
STRING; 4932.YCR075C; -.
TCDB; 2.A.43.1.3; the lysosomal cystine transporter (lct) family.
PaxDb; P17261; -.
PRIDE; P17261; -.
EnsemblFungi; CAA42264; CAA42264; CAA42264.
EnsemblFungi; YCR075C; YCR075C; YCR075C.
GeneID; 850438; -.
KEGG; sce:YCR075C; -.
EuPathDB; FungiDB:YCR075C; -.
SGD; S000000671; ERS1.
GeneTree; ENSGT00390000005338; -.
HOGENOM; HOG000000908; -.
InParanoid; P17261; -.
KO; K12386; -.
OrthoDB; EOG092C4BRM; -.
BioCyc; YEAST:G3O-29374-MONOMER; -.
Reactome; R-SCE-425393; Transport of inorganic cations/anions and amino acids/oligopeptides.
Reactome; R-SCE-5223345; Miscellaneous transport and binding events.
PRO; PR:P17261; -.
Proteomes; UP000002311; Chromosome III.
GO; GO:0005768; C:endosome; IDA:SGD.
GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO; GO:0000324; C:fungal-type vacuole; IDA:SGD.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IDA:SGD.
GO; GO:0005774; C:vacuolar membrane; IBA:GO_Central.
GO; GO:0015184; F:L-cystine transmembrane transporter activity; IGI:SGD.
GO; GO:0015811; P:L-cystine transport; IDA:SGD.
GO; GO:0055085; P:transmembrane transport; ISS:SGD.
InterPro; IPR005282; LC_transporter.
InterPro; IPR006603; PQ-loop_rpt.
PANTHER; PTHR13131; PTHR13131; 1.
Pfam; PF04193; PQ-loop; 2.
SMART; SM00679; CTNS; 2.
TIGRFAMs; TIGR00951; 2A43; 1.
3: Inferred from homology;
Complete proteome; Endosome; Glycoprotein; Membrane;
Reference proteome; Repeat; Transmembrane; Transmembrane helix;
Transport; Vacuole.
CHAIN 1 260 Cystine transporter.
TRANSMEM 7 28 Helical. {ECO:0000255}.
TRANSMEM 40 62 Helical. {ECO:0000255}.
TRANSMEM 81 102 Helical. {ECO:0000255}.
TRANSMEM 118 138 Helical. {ECO:0000255}.
TRANSMEM 151 175 Helical. {ECO:0000255}.
TRANSMEM 185 205 Helical. {ECO:0000255}.
TRANSMEM 227 247 Helical. {ECO:0000255}.
DOMAIN 1 67 PQ-loop 1.
DOMAIN 162 212 PQ-loop 2.
CARBOHYD 177 177 N-linked (GlcNAc...) asparagine.
SEQUENCE 260 AA; 30116 MW; BF9E129E44D20655 CRC64;

Related products :

Catalog number Product name Quantity
EH1243 Cystine per glutamate transporter Elisa Kit 96T
CSB-EL021711HU Human Cystine per glutamate transporter(SLC7A11) ELISA kit 96T
E10985h ELISA Kit FOR Cystine per glutamate transporter; organism: Human; gene name: SLC7A11 96T
E10985m ELISA Kit FOR Cystine per glutamate transporter; organism: Mouse; gene name: Slc7a11 96T
KE021 Anti Mouse Cystine _ Glutamic Acid Transporter (xCT) Polyclonal Antibody 0.1
EIAAB44555 Homo sapiens,Human,IFITMD3,Interferon-induced transmembrane domain-containing protein D3,LOST1,Protein located at seventeen-p-thirteen point three 1,Tumor suppressor candidate 5,TUSC5
EIAAB40267 Dudulin-2,Metalloreductase STEAP3,Mouse,Mus musculus,Protein nm1054,Six-transmembrane epithelial antigen of prostate 3,Steap3,Tsap6,Tumor suppressor-activated pathway protein 6
27-911 CLDN23 is a four-transmembrane protein with WWCC motif, defined by W-X (17-22)-W-X (2)-C-X (8-10)-C. It is a candidate tumor suppressor gene implicated in intestinal-type gastric cancer. 0.05 mg
30-622 ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a componen 0.1 mg
EIAAB43187 Homo sapiens,Human,Protein M83,TMEM6,TMEM8,TMEM8A,Transmembrane protein 6,Transmembrane protein 8,Transmembrane protein 8A
EIAAB24997 Bos taurus,Bovine,Membrane magnesium transporter 1,MMGT1,TMEM32,Transmembrane protein 32
EIAAB25000 Membrane magnesium transporter 1,Mmgt1,Mouse,Mus musculus,Tmem32,Transmembrane protein 32
EIAAB24998 Membrane magnesium transporter 1,Mmgt1,Rat,Rattus norvegicus,Tmem32,Transmembrane protein 32
EIAAB24999 Homo sapiens,Human,Membrane magnesium transporter 1,MMGT1,TMEM32,Transmembrane protein 32
EIAAB43035 21 kDa transmembrane-trafficking protein,Integral membrane protein p23,Oryctolagus cuniculus,Rabbit,TMED10,TMP21,Transmembrane emp24 domain-containing protein 10,Transmembrane protein Tmp21
EIAAB41071 Homo sapiens,Human,TMEM200B,Transmembrane protein 200B,Transmembrane protein TTMA,TTMB,Two transmembrane domain-containing family member B
25-904 SLC22A14 is a member of the organic-cation transporter family. SLC22A14 is a transmembrane protein which is thought to transport small molecules and since this protein is conserved among several speci 0.05 mg
EIAAB43033 21 kDa transmembrane-trafficking protein,Homo sapiens,Human,p23,p24delta,S31I125,S31III125,TMED10,TMP21,Tmp-21-I,Transmembrane emp24 domain-containing protein 10,Transmembrane protein Tmp21
EIAAB40998 HBE120,Homo sapiens,Human,KIAA1944,Mature OL transmembrane protein,Mature oligodendrocytes transmembrane protein,MOLT,TMEM132D,Transmembrane protein 132D
25-924 SLC39A4 is a member of the zinc_iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 res 0.05 mg
25-900 SLC22A13 is a member of the organic-cation transporter family. SLC22A13 is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and i 0.05 mg
HCM011 Selenite Cystine Broth (Fuid Selenite Cystine medium)(SC) 10x 500g
EIAAB42684 Mouse,Mus musculus,Tmem165,TPA-regulated locus protein,Tparl,Transmembrane protein 165,Transmembrane protein PFT27,Transmembrane protein TPARL
EIAAB40266 Dudulin-2,Homo sapiens,hpHyde,hTSAP6,Human,Metalloreductase STEAP3,pHyde,Six-transmembrane epithelial antigen of prostate 3,STEAP3,TSAP6,Tumor suppressor-activated pathway protein 6
EIAAB40138 HCCS1,HCCS-1,Homo sapiens,Human,Human cervical cancer suppressor gene 1 protein,ST20,Suppressor of tumorigenicity 20 protein


GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur

Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur



9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017


france@gentaur.com | Gentaur

Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123

GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U

spain@gentaur.com | Gentaur

ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636

GENTAUR Poland Sp. z o.o.

ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556


Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur