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Cytochrome P450 hydroxylase

 C9W346_9ACTN            Unreviewed;       398 AA.
C9W346;
24-NOV-2009, integrated into UniProtKB/TrEMBL.
24-NOV-2009, sequence version 1.
25-OCT-2017, entry version 26.
SubName: Full=Cytochrome P450 hydroxylase {ECO:0000313|EMBL:ACN29715.1};
Name=nokP {ECO:0000313|EMBL:ACN29715.1};
Nonomuraea longicatena.
Bacteria; Actinobacteria; Streptosporangiales; Streptosporangiaceae;
Nonomuraea.
NCBI_TaxID=83682 {ECO:0000313|EMBL:ACN29715.1};
[1] {ECO:0000313|EMBL:ACN29715.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NRRL15532 {ECO:0000313|EMBL:ACN29715.1};
Chiu H.-T.;
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:ACN29715.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NRRL15532 {ECO:0000313|EMBL:ACN29715.1};
PubMed=19756308; DOI=10.1039/b905293c;
Chiu H.T., Chen Y.L., Chen C.Y., Jin C., Lee M.N., Lin Y.C.;
"Molecular cloning, sequence analysis and functional characterization
of the gene cluster for biosynthesis of K-252a and its analogs.";
Mol. Biosyst. 5:1180-1191(2009).
-!- SIMILARITY: Belongs to the cytochrome P450 family.
{ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS00578603}.
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EMBL; FJ031030; ACN29715.1; -; Genomic_DNA.
ProteinModelPortal; C9W346; -.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0005506; F:iron ion binding; IEA:InterPro.
GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
Gene3D; 1.10.630.10; -; 1.
InterPro; IPR001128; Cyt_P450.
InterPro; IPR002397; Cyt_P450_B.
InterPro; IPR017972; Cyt_P450_CS.
InterPro; IPR036396; Cyt_P450_sf.
Pfam; PF00067; p450; 1.
PRINTS; PR00359; BP450.
PRINTS; PR00385; P450.
SUPFAM; SSF48264; SSF48264; 1.
PROSITE; PS00086; CYTOCHROME_P450; 1.
3: Inferred from homology;
Heme {ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS00532861};
Iron {ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS00532861};
Metal-binding {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00532861};
Monooxygenase {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00532857};
Oxidoreductase {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00532857}.
SEQUENCE 398 AA; 43818 MW; 2ECC8EED4E928A02 CRC64;
MTQTCPLPEF PFVRSSALDA DARGIELLGD APVVRARYRD GGELWVALGN EAARQVVTDP
RFSRHAAVEP DGPKIGNAVP DLLISMDGKA HLAARRLFSK AFTPRMVENM RPWIEGLVGE
LLDQVERAGP PLDLVEHFTA PLPVSVICQL LGVPYEDRGS FMDWTDRMLG DTGYTPQEIG
EGIGNLRNYM RDLVAAKRAH PGDDLTTELI HVRAAGARLT EDQLVNNLFL MLGAGHDTTL
KQLSNSLLLL LTRREEYARL CERPDLIPNA VEELLRYLLL SPTGMLIRVA VQDVELGGQR
VRAGETVAVL HHVANRDPAL FACPNDLDLG REDAIKHLSF GAGPHFCLGA PLARLELATA
LTELTRRLPG LRLAVPPQEV PWKEGGLQRG PLRLPVEW


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