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Cytochrome c oxidase polypeptide VIII, mitochondrial (EC 1.9.3.1)

 COX8_SCHPO              Reviewed;          66 AA.
Q9P4W1;
07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
28-FEB-2018, entry version 84.
RecName: Full=Cytochrome c oxidase polypeptide VIII, mitochondrial;
EC=1.9.3.1;
Flags: Precursor;
Name=cox8; ORFNames=SPAC24C9.16c;
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
Schizosaccharomycetes; Schizosaccharomycetales;
Schizosaccharomycetaceae; Schizosaccharomyces.
NCBI_TaxID=284812;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=972 / ATCC 24843;
PubMed=11859360; DOI=10.1038/nature724;
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
-!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
ferricytochrome c + 2 H(2)O.
-!- SUBUNIT: Composed of at least 11 subunits. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
-!- SIMILARITY: Belongs to the cytochrome c oxidase VIIc family.
{ECO:0000305}.
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EMBL; CU329670; CAB71272.1; -; Genomic_DNA.
RefSeq; NP_594028.1; NM_001019453.2.
SMR; Q9P4W1; -.
BioGrid; 279098; 6.
STRING; 4896.SPAC24C9.16c.1; -.
MaxQB; Q9P4W1; -.
PaxDb; Q9P4W1; -.
PRIDE; Q9P4W1; -.
EnsemblFungi; SPAC24C9.16c.1; SPAC24C9.16c.1:pep; SPAC24C9.16c.
GeneID; 2542644; -.
KEGG; spo:SPAC24C9.16c; -.
EuPathDB; FungiDB:SPAC24C9.16c; -.
PomBase; SPAC24C9.16c; cox8.
KO; K02272; -.
OrthoDB; EOG092C5XSY; -.
PRO; PR:Q9P4W1; -.
Proteomes; UP000002485; Chromosome I.
GO; GO:0005751; C:mitochondrial respiratory chain complex IV; ISS:PomBase.
GO; GO:0005739; C:mitochondrion; HDA:PomBase.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
GO; GO:0009060; P:aerobic respiration; ISS:PomBase.
GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IBA:GO_Central.
CDD; cd00929; Cyt_c_Oxidase_VIIc; 1.
InterPro; IPR004202; COX7C/Cox8.
InterPro; IPR036636; COX7C/Cox8_sf.
PANTHER; PTHR13313; PTHR13313; 1.
Pfam; PF02935; COX7C; 1.
SUPFAM; SSF81427; SSF81427; 1.
3: Inferred from homology;
Complete proteome; Membrane; Mitochondrion;
Mitochondrion inner membrane; Oxidoreductase; Reference proteome;
Transit peptide.
TRANSIT 1 ? Mitochondrion. {ECO:0000255}.
CHAIN ? 66 Cytochrome c oxidase polypeptide VIII,
mitochondrial.
/FTId=PRO_0000006172.
SEQUENCE 66 AA; 7502 MW; E6E6559AF6E3D287 CRC64;
MLRYSLQARS ALRGVRFSSS HSAPKPGSTI PFYINKKPLP TLLYFGTFGV IFSIPFIVVK
YHNRNL


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