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Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)

 A0A0B5EJI9_RADBA        Unreviewed;       228 AA.
A0A0B5EJI9;
01-APR-2015, integrated into UniProtKB/TrEMBL.
01-APR-2015, sequence version 1.
23-MAY-2018, entry version 11.
RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
Flags: Fragment;
Name=COI {ECO:0000313|EMBL:AJE70728.1};
Radix balthica (Wandering pond snail) (Radix ovata).
Mitochondrion {ECO:0000313|EMBL:AJE70728.1}.
Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
Heterobranchia; Euthyneura; Panpulmonata; Hygrophila; Lymnaeoidea;
Lymnaeidae; Radix.
NCBI_TaxID=582868 {ECO:0000313|EMBL:AJE70728.1};
[1] {ECO:0000313|EMBL:AJE70728.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BSC10 {ECO:0000313|EMBL:AJE70336.1},
BSC2 {ECO:0000313|EMBL:AJE70339.1},
BSC8 {ECO:0000313|EMBL:AJE70345.1},
CMT2 {ECO:0000313|EMBL:AJE70410.1},
CMT4 {ECO:0000313|EMBL:AJE70412.1},
CMT5 {ECO:0000313|EMBL:AJE70413.1},
CPG1 {ECO:0000313|EMBL:AJE70417.1},
CPG2 {ECO:0000313|EMBL:AJE70428.1},
CPG4 {ECO:0000313|EMBL:AJE70431.1},
DAS11 {ECO:0000313|EMBL:AJE70439.1},
DAS12 {ECO:0000313|EMBL:AJE70440.1},
DAS13 {ECO:0000313|EMBL:AJE70441.1},
DAS18 {ECO:0000313|EMBL:AJE70446.1},
DAS3 {ECO:0000313|EMBL:AJE70448.1},
DAS4 {ECO:0000313|EMBL:AJE70449.1},
DAS5 {ECO:0000313|EMBL:AJE70450.1},
DAS6 {ECO:0000313|EMBL:AJE70451.1},
DAS7 {ECO:0000313|EMBL:AJE70452.1},
DAS8 {ECO:0000313|EMBL:AJE70453.1},
DAS9 {ECO:0000313|EMBL:AJE70454.1},
DUN1 {ECO:0000313|EMBL:AJE70478.1},
DUN2 {ECO:0000313|EMBL:AJE70479.1},
DUN8 {ECO:0000313|EMBL:AJE70485.1},
FEL1 {ECO:0000313|EMBL:AJE70526.1},
FEL13 {ECO:0000313|EMBL:AJE70530.1},
FEL14 {ECO:0000313|EMBL:AJE70531.1},
FEL15 {ECO:0000313|EMBL:AJE70532.1},
FEL16 {ECO:0000313|EMBL:AJE70533.1},
FEL18 {ECO:0000313|EMBL:AJE70535.1},
FEL2 {ECO:0000313|EMBL:AJE70537.1},
FEL20 {ECO:0000313|EMBL:AJE70538.1},
FEL6 {ECO:0000313|EMBL:AJE70542.1},
FEL7 {ECO:0000313|EMBL:AJE70543.1},
FEL8 {ECO:0000313|EMBL:AJE70544.1},
GNL1 {ECO:0000313|EMBL:AJE70553.1},
GNL10 {ECO:0000313|EMBL:AJE70554.1},
GNL12 {ECO:0000313|EMBL:AJE70556.1},
GNL2 {ECO:0000313|EMBL:AJE70557.1},
GNL3 {ECO:0000313|EMBL:AJE70558.1},
GNL4 {ECO:0000313|EMBL:AJE70559.1},
GNL6 {ECO:0000313|EMBL:AJE70561.1},
GNL7 {ECO:0000313|EMBL:AJE70562.1},
HEN6 {ECO:0000313|EMBL:AJE70579.1},
HEN7 {ECO:0000313|EMBL:AJE70580.1},
HEN8 {ECO:0000313|EMBL:AJE70581.1},
ISG10 {ECO:0000313|EMBL:AJE70583.1},
ISG12 {ECO:0000313|EMBL:AJE70584.1},
ISG13 {ECO:0000313|EMBL:AJE70585.1},
ISG2 {ECO:0000313|EMBL:AJE70592.1},
ISG3 {ECO:0000313|EMBL:AJE70594.1},
ISG4 {ECO:0000313|EMBL:AJE70595.1},
ISG5 {ECO:0000313|EMBL:AJE70596.1},
ISG6 {ECO:0000313|EMBL:AJE70597.1},
JRC12 {ECO:0000313|EMBL:AJE70604.1},
JRC14 {ECO:0000313|EMBL:AJE70606.1},
JRC3 {ECO:0000313|EMBL:AJE70608.1},
JRC5 {ECO:0000313|EMBL:AJE70610.1},
LES4 {ECO:0000313|EMBL:AJE70633.1},
LES7 {ECO:0000313|EMBL:AJE70636.1},
LMY1 {ECO:0000313|EMBL:AJE70639.1},
LMY11 {ECO:0000313|EMBL:AJE70641.1},
LMY12 {ECO:0000313|EMBL:AJE70642.1},
LMY2 {ECO:0000313|EMBL:AJE70646.1},
LMY3 {ECO:0000313|EMBL:AJE70647.1},
LMY4 {ECO:0000313|EMBL:AJE70648.1},
LMY5 {ECO:0000313|EMBL:AJE70649.1},
LMY8 {ECO:0000313|EMBL:AJE70650.1},
PYO1 {ECO:0000313|EMBL:AJE70718.1},
PYO10 {ECO:0000313|EMBL:AJE70719.1},
PYO11 {ECO:0000313|EMBL:AJE70720.1},
PYO13 {ECO:0000313|EMBL:AJE70722.1},
PYO14 {ECO:0000313|EMBL:AJE70723.1},
PYO4 {ECO:0000313|EMBL:AJE70726.1},
PYO5 {ECO:0000313|EMBL:AJE70727.1},
PYO6 {ECO:0000313|EMBL:AJE70728.1},
PYO7 {ECO:0000313|EMBL:AJE70729.1},
PYO8 {ECO:0000313|EMBL:AJE70730.1},
PYO9 {ECO:0000313|EMBL:AJE70731.1},
RSL2 {ECO:0000313|EMBL:AJE70736.1},
SSB10 {ECO:0000313|EMBL:AJE70744.1},
SSB11 {ECO:0000313|EMBL:AJE70745.1},
SSB2 {ECO:0000313|EMBL:AJE70747.1},
SSB5 {ECO:0000313|EMBL:AJE70750.1},
SSB7 {ECO:0000313|EMBL:AJE70752.1},
URG1 {ECO:0000313|EMBL:AJE70809.1}, and
URG7 {ECO:0000313|EMBL:AJE70815.1};
PubMed=25533031; DOI=10.1111/mec.13049;
Patel S., Schell T., Eifert C., Feldmeyer B., Pfenninger M.;
"Characterizing a hybrid zone between a cryptic species pair of
freshwater snails.";
Mol. Ecol. 24:643-655(2015).
-!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
chain that catalyzes the reduction of oxygen to water. Subunits 1-
3 form the functional core of the enzyme complex. CO I is the
catalytic subunit of the enzyme. Electrons originating in
cytochrome c are transferred via the copper A center of subunit 2
and heme A of subunit 1 to the bimetallic center formed by heme A3
and copper B. {ECO:0000256|RuleBase:RU000369}.
-!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
-!- PATHWAY: Energy metabolism; oxidative phosphorylation.
{ECO:0000256|RuleBase:RU000369}.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
{ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
{ECO:0000256|RuleBase:RU000369}.
-!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
{ECO:0000256|RuleBase:RU000369}.
-----------------------------------------------------------------------
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EMBL; KP242368; AJE70336.1; -; Genomic_DNA.
EMBL; KP242371; AJE70339.1; -; Genomic_DNA.
EMBL; KP242377; AJE70345.1; -; Genomic_DNA.
EMBL; KP242442; AJE70410.1; -; Genomic_DNA.
EMBL; KP242444; AJE70412.1; -; Genomic_DNA.
EMBL; KP242445; AJE70413.1; -; Genomic_DNA.
EMBL; KP242449; AJE70417.1; -; Genomic_DNA.
EMBL; KP242460; AJE70428.1; -; Genomic_DNA.
EMBL; KP242463; AJE70431.1; -; Genomic_DNA.
EMBL; KP242471; AJE70439.1; -; Genomic_DNA.
EMBL; KP242472; AJE70440.1; -; Genomic_DNA.
EMBL; KP242473; AJE70441.1; -; Genomic_DNA.
EMBL; KP242478; AJE70446.1; -; Genomic_DNA.
EMBL; KP242480; AJE70448.1; -; Genomic_DNA.
EMBL; KP242481; AJE70449.1; -; Genomic_DNA.
EMBL; KP242482; AJE70450.1; -; Genomic_DNA.
EMBL; KP242483; AJE70451.1; -; Genomic_DNA.
EMBL; KP242484; AJE70452.1; -; Genomic_DNA.
EMBL; KP242485; AJE70453.1; -; Genomic_DNA.
EMBL; KP242486; AJE70454.1; -; Genomic_DNA.
EMBL; KP242510; AJE70478.1; -; Genomic_DNA.
EMBL; KP242511; AJE70479.1; -; Genomic_DNA.
EMBL; KP242517; AJE70485.1; -; Genomic_DNA.
EMBL; KP242558; AJE70526.1; -; Genomic_DNA.
EMBL; KP242562; AJE70530.1; -; Genomic_DNA.
EMBL; KP242563; AJE70531.1; -; Genomic_DNA.
EMBL; KP242564; AJE70532.1; -; Genomic_DNA.
EMBL; KP242565; AJE70533.1; -; Genomic_DNA.
EMBL; KP242567; AJE70535.1; -; Genomic_DNA.
EMBL; KP242569; AJE70537.1; -; Genomic_DNA.
EMBL; KP242570; AJE70538.1; -; Genomic_DNA.
EMBL; KP242574; AJE70542.1; -; Genomic_DNA.
EMBL; KP242575; AJE70543.1; -; Genomic_DNA.
EMBL; KP242576; AJE70544.1; -; Genomic_DNA.
EMBL; KP242585; AJE70553.1; -; Genomic_DNA.
EMBL; KP242586; AJE70554.1; -; Genomic_DNA.
EMBL; KP242588; AJE70556.1; -; Genomic_DNA.
EMBL; KP242589; AJE70557.1; -; Genomic_DNA.
EMBL; KP242590; AJE70558.1; -; Genomic_DNA.
EMBL; KP242591; AJE70559.1; -; Genomic_DNA.
EMBL; KP242593; AJE70561.1; -; Genomic_DNA.
EMBL; KP242594; AJE70562.1; -; Genomic_DNA.
EMBL; KP242611; AJE70579.1; -; Genomic_DNA.
EMBL; KP242612; AJE70580.1; -; Genomic_DNA.
EMBL; KP242613; AJE70581.1; -; Genomic_DNA.
EMBL; KP242615; AJE70583.1; -; Genomic_DNA.
EMBL; KP242616; AJE70584.1; -; Genomic_DNA.
EMBL; KP242617; AJE70585.1; -; Genomic_DNA.
EMBL; KP242624; AJE70592.1; -; Genomic_DNA.
EMBL; KP242626; AJE70594.1; -; Genomic_DNA.
EMBL; KP242627; AJE70595.1; -; Genomic_DNA.
EMBL; KP242628; AJE70596.1; -; Genomic_DNA.
EMBL; KP242629; AJE70597.1; -; Genomic_DNA.
EMBL; KP242636; AJE70604.1; -; Genomic_DNA.
EMBL; KP242638; AJE70606.1; -; Genomic_DNA.
EMBL; KP242640; AJE70608.1; -; Genomic_DNA.
EMBL; KP242642; AJE70610.1; -; Genomic_DNA.
EMBL; KP242665; AJE70633.1; -; Genomic_DNA.
EMBL; KP242668; AJE70636.1; -; Genomic_DNA.
EMBL; KP242671; AJE70639.1; -; Genomic_DNA.
EMBL; KP242673; AJE70641.1; -; Genomic_DNA.
EMBL; KP242674; AJE70642.1; -; Genomic_DNA.
EMBL; KP242678; AJE70646.1; -; Genomic_DNA.
EMBL; KP242679; AJE70647.1; -; Genomic_DNA.
EMBL; KP242680; AJE70648.1; -; Genomic_DNA.
EMBL; KP242681; AJE70649.1; -; Genomic_DNA.
EMBL; KP242682; AJE70650.1; -; Genomic_DNA.
EMBL; KP242751; AJE70718.1; -; Genomic_DNA.
EMBL; KP242752; AJE70719.1; -; Genomic_DNA.
EMBL; KP242753; AJE70720.1; -; Genomic_DNA.
EMBL; KP242755; AJE70722.1; -; Genomic_DNA.
EMBL; KP242756; AJE70723.1; -; Genomic_DNA.
EMBL; KP242759; AJE70726.1; -; Genomic_DNA.
EMBL; KP242760; AJE70727.1; -; Genomic_DNA.
EMBL; KP242761; AJE70728.1; -; Genomic_DNA.
EMBL; KP242762; AJE70729.1; -; Genomic_DNA.
EMBL; KP242763; AJE70730.1; -; Genomic_DNA.
EMBL; KP242764; AJE70731.1; -; Genomic_DNA.
EMBL; KP242769; AJE70736.1; -; Genomic_DNA.
EMBL; KP242777; AJE70744.1; -; Genomic_DNA.
EMBL; KP242778; AJE70745.1; -; Genomic_DNA.
EMBL; KP242780; AJE70747.1; -; Genomic_DNA.
EMBL; KP242783; AJE70750.1; -; Genomic_DNA.
EMBL; KP242785; AJE70752.1; -; Genomic_DNA.
EMBL; KP242842; AJE70809.1; -; Genomic_DNA.
EMBL; KP242848; AJE70815.1; -; Genomic_DNA.
UniPathway; UPA00705; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
Gene3D; 1.20.210.10; -; 1.
InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
InterPro; IPR000883; Cyt_C_Oxase_1.
PANTHER; PTHR10422; PTHR10422; 1.
Pfam; PF00115; COX1; 1.
PRINTS; PR01165; CYCOXIDASEI.
SUPFAM; SSF81442; SSF81442; 1.
PROSITE; PS50855; COX1; 1.
3: Inferred from homology;
Copper {ECO:0000256|RuleBase:RU000369};
Electron transport {ECO:0000256|RuleBase:RU000369};
Heme {ECO:0000256|RuleBase:RU000369};
Iron {ECO:0000256|RuleBase:RU000369};
Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
Metal-binding {ECO:0000256|RuleBase:RU000369};
Mitochondrion {ECO:0000256|RuleBase:RU000369};
Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
Oxidoreductase {ECO:0000256|RuleBase:RU000369};
Respiratory chain {ECO:0000256|RuleBase:RU000369};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius};
Transport {ECO:0000256|RuleBase:RU000369}.
TRANSMEM 7 27 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 39 68 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 89 113 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 133 158 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 170 197 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 1 228 COX1. {ECO:0000259|PROSITE:PS50855}.
NON_TER 1 1 {ECO:0000313|EMBL:AJE70728.1}.
NON_TER 228 228 {ECO:0000313|EMBL:AJE70728.1}.
SEQUENCE 228 AA; 24935 MW; B7BEA7B16023BFDC CRC64;
KDIGTLYMIF GVWCGLVGTG LSLLIRLELG TSMVLIDEHF YNVIVTAHAF VMIFFMVMPM
MIGGFGNWMV PLLIGAPDMS FPRMNNMSFW LLPPSFVLLL CSSMVEGGVG TGWTVYPPLS
GPIAHGGSSV DLAIFSLHLA GLSSILGAIN FITTIFNMRS PGITLERMSL FVWSVLITAF
LLLLSLPVLA GAITMLLTDR NFNTTFFDPA GGGDPILYQH LFWFFGHP


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