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Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)

 A0A0C4HUK6_EQUAS        Unreviewed;       209 AA.
A0A0C4HUK6;
29-APR-2015, integrated into UniProtKB/TrEMBL.
29-APR-2015, sequence version 1.
23-MAY-2018, entry version 12.
RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
Flags: Fragment;
Name=COX1 {ECO:0000313|EMBL:AGQ45915.1};
Synonyms=cox1 {ECO:0000313|EMBL:AGQ45934.1};
Equus asinus (Donkey) (Equus africanus asinus).
Mitochondrion {ECO:0000313|EMBL:AGQ45915.1}.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9793 {ECO:0000313|EMBL:AGQ45915.1};
[1] {ECO:0000313|EMBL:AGQ45934.1}
NUCLEOTIDE SEQUENCE.
Hu J.H., Zhang Y.Q., Chen S.L., Yao H.;
"Identification of donkey hide from other mammal hides producing
gelatin by Cox1 sequence and the genetic diversity study of Chinese
donkey.";
Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:AGQ45915.1}
NUCLEOTIDE SEQUENCE.
Hu J.H., Zhong Y.Q., Chen S.L., Yao H.;
"Identification of donkey hide from other mammal hides produing
gelatin by Cox1 sequence and the genetic diversity study of Chinese
donkey.";
Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
chain that catalyzes the reduction of oxygen to water. Subunits 1-
3 form the functional core of the enzyme complex. CO I is the
catalytic subunit of the enzyme. Electrons originating in
cytochrome c are transferred via the copper A center of subunit 2
and heme A of subunit 1 to the bimetallic center formed by heme A3
and copper B. {ECO:0000256|RuleBase:RU000369}.
-!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
-!- PATHWAY: Energy metabolism; oxidative phosphorylation.
{ECO:0000256|RuleBase:RU000369}.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
{ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
{ECO:0000256|RuleBase:RU000369}.
-!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
{ECO:0000256|RuleBase:RU000369}.
-----------------------------------------------------------------------
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EMBL; KC693987; AGQ45833.1; -; Genomic_DNA.
EMBL; KC693998; AGQ45844.1; -; Genomic_DNA.
EMBL; KC693999; AGQ45845.1; -; Genomic_DNA.
EMBL; KC694000; AGQ45846.1; -; Genomic_DNA.
EMBL; KC694001; AGQ45847.1; -; Genomic_DNA.
EMBL; KC694002; AGQ45848.1; -; Genomic_DNA.
EMBL; KC694003; AGQ45849.1; -; Genomic_DNA.
EMBL; KC694004; AGQ45850.1; -; Genomic_DNA.
EMBL; KC694005; AGQ45851.1; -; Genomic_DNA.
EMBL; KC694006; AGQ45852.1; -; Genomic_DNA.
EMBL; KC694007; AGQ45853.1; -; Genomic_DNA.
EMBL; KC694008; AGQ45854.1; -; Genomic_DNA.
EMBL; KC694009; AGQ45855.1; -; Genomic_DNA.
EMBL; KC694010; AGQ45856.1; -; Genomic_DNA.
EMBL; KC694011; AGQ45857.1; -; Genomic_DNA.
EMBL; KC694012; AGQ45858.1; -; Genomic_DNA.
EMBL; KC694013; AGQ45859.1; -; Genomic_DNA.
EMBL; KC694014; AGQ45860.1; -; Genomic_DNA.
EMBL; KC694015; AGQ45861.1; -; Genomic_DNA.
EMBL; KC694016; AGQ45862.1; -; Genomic_DNA.
EMBL; KC694017; AGQ45863.1; -; Genomic_DNA.
EMBL; KC694018; AGQ45864.1; -; Genomic_DNA.
EMBL; KC694019; AGQ45865.1; -; Genomic_DNA.
EMBL; KC694020; AGQ45866.1; -; Genomic_DNA.
EMBL; KC694021; AGQ45867.1; -; Genomic_DNA.
EMBL; KC694022; AGQ45868.1; -; Genomic_DNA.
EMBL; KC694023; AGQ45869.1; -; Genomic_DNA.
EMBL; KC694024; AGQ45870.1; -; Genomic_DNA.
EMBL; KC694025; AGQ45871.1; -; Genomic_DNA.
EMBL; KC694026; AGQ45872.1; -; Genomic_DNA.
EMBL; KC694027; AGQ45873.1; -; Genomic_DNA.
EMBL; KC694028; AGQ45874.1; -; Genomic_DNA.
EMBL; KC694029; AGQ45875.1; -; Genomic_DNA.
EMBL; KC694030; AGQ45876.1; -; Genomic_DNA.
EMBL; KC694031; AGQ45877.1; -; Genomic_DNA.
EMBL; KC694032; AGQ45878.1; -; Genomic_DNA.
EMBL; KC694033; AGQ45879.1; -; Genomic_DNA.
EMBL; KC694034; AGQ45880.1; -; Genomic_DNA.
EMBL; KC694035; AGQ45881.1; -; Genomic_DNA.
EMBL; KC694036; AGQ45882.1; -; Genomic_DNA.
EMBL; KC694037; AGQ45883.1; -; Genomic_DNA.
EMBL; KC694038; AGQ45884.1; -; Genomic_DNA.
EMBL; KC694039; AGQ45885.1; -; Genomic_DNA.
EMBL; KC694040; AGQ45886.1; -; Genomic_DNA.
EMBL; KC694041; AGQ45887.1; -; Genomic_DNA.
EMBL; KC694042; AGQ45888.1; -; Genomic_DNA.
EMBL; KC694043; AGQ45889.1; -; Genomic_DNA.
EMBL; KC694044; AGQ45890.1; -; Genomic_DNA.
EMBL; KC694045; AGQ45891.1; -; Genomic_DNA.
EMBL; KC694046; AGQ45892.1; -; Genomic_DNA.
EMBL; KC694047; AGQ45893.1; -; Genomic_DNA.
EMBL; KC694048; AGQ45894.1; -; Genomic_DNA.
EMBL; KC694049; AGQ45895.1; -; Genomic_DNA.
EMBL; KC694050; AGQ45896.1; -; Genomic_DNA.
EMBL; KC694051; AGQ45897.1; -; Genomic_DNA.
EMBL; KC694052; AGQ45898.1; -; Genomic_DNA.
EMBL; KC694053; AGQ45899.1; -; Genomic_DNA.
EMBL; KC694054; AGQ45900.1; -; Genomic_DNA.
EMBL; KC694055; AGQ45901.1; -; Genomic_DNA.
EMBL; KC694056; AGQ45902.1; -; Genomic_DNA.
EMBL; KC694057; AGQ45903.1; -; Genomic_DNA.
EMBL; KC694058; AGQ45904.1; -; Genomic_DNA.
EMBL; KC694059; AGQ45905.1; -; Genomic_DNA.
EMBL; KC694060; AGQ45906.1; -; Genomic_DNA.
EMBL; KC694061; AGQ45907.1; -; Genomic_DNA.
EMBL; KC694062; AGQ45908.1; -; Genomic_DNA.
EMBL; KC694063; AGQ45909.1; -; Genomic_DNA.
EMBL; KC694065; AGQ45911.1; -; Genomic_DNA.
EMBL; KC694066; AGQ45912.1; -; Genomic_DNA.
EMBL; KC694067; AGQ45913.1; -; Genomic_DNA.
EMBL; KC694068; AGQ45914.1; -; Genomic_DNA.
EMBL; KC694069; AGQ45915.1; -; Genomic_DNA.
EMBL; KC694070; AGQ45916.1; -; Genomic_DNA.
EMBL; KC694071; AGQ45917.1; -; Genomic_DNA.
EMBL; KC694072; AGQ45918.1; -; Genomic_DNA.
EMBL; KC694073; AGQ45919.1; -; Genomic_DNA.
EMBL; KC694074; AGQ45920.1; -; Genomic_DNA.
EMBL; KC694075; AGQ45921.1; -; Genomic_DNA.
EMBL; KC694076; AGQ45922.1; -; Genomic_DNA.
EMBL; KC694077; AGQ45923.1; -; Genomic_DNA.
EMBL; KC694078; AGQ45924.1; -; Genomic_DNA.
EMBL; KC694079; AGQ45925.1; -; Genomic_DNA.
EMBL; KC694080; AGQ45926.1; -; Genomic_DNA.
EMBL; KC694081; AGQ45927.1; -; Genomic_DNA.
EMBL; KC694082; AGQ45928.1; -; Genomic_DNA.
EMBL; KC694083; AGQ45929.1; -; Genomic_DNA.
EMBL; KC694084; AGQ45930.1; -; Genomic_DNA.
EMBL; KC694085; AGQ45931.1; -; Genomic_DNA.
EMBL; KC694086; AGQ45932.1; -; Genomic_DNA.
EMBL; KC694087; AGQ45933.1; -; Genomic_DNA.
EMBL; KC694088; AGQ45934.1; -; Genomic_DNA.
EMBL; KC694089; AGQ45935.1; -; Genomic_DNA.
EMBL; KC694090; AGQ45936.1; -; Genomic_DNA.
EMBL; KC694091; AGQ45937.1; -; Genomic_DNA.
EMBL; KC694092; AGQ45938.1; -; Genomic_DNA.
EMBL; KC694093; AGQ45939.1; -; Genomic_DNA.
EMBL; KC694094; AGQ45940.1; -; Genomic_DNA.
EMBL; KC694095; AGQ45941.1; -; Genomic_DNA.
EMBL; KC694096; AGQ45942.1; -; Genomic_DNA.
EMBL; KC694097; AGQ45943.1; -; Genomic_DNA.
UniPathway; UPA00705; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
Gene3D; 1.20.210.10; -; 1.
InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
InterPro; IPR000883; Cyt_C_Oxase_1.
PANTHER; PTHR10422; PTHR10422; 1.
Pfam; PF00115; COX1; 1.
PRINTS; PR01165; CYCOXIDASEI.
SUPFAM; SSF81442; SSF81442; 1.
PROSITE; PS50855; COX1; 1.
3: Inferred from homology;
Copper {ECO:0000256|RuleBase:RU000369};
Electron transport {ECO:0000256|RuleBase:RU000369};
Heme {ECO:0000256|RuleBase:RU000369};
Iron {ECO:0000256|RuleBase:RU000369};
Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
Metal-binding {ECO:0000256|RuleBase:RU000369};
Mitochondrion {ECO:0000256|RuleBase:RU000369};
Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
Oxidoreductase {ECO:0000256|RuleBase:RU000369};
Respiratory chain {ECO:0000256|RuleBase:RU000369};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius};
Transport {ECO:0000256|RuleBase:RU000369}.
TRANSMEM 18 37 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 57 83 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 104 128 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 148 171 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 183 206 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 1 209 COX1. {ECO:0000259|PROSITE:PS50855}.
NON_TER 209 209 {ECO:0000313|EMBL:AGQ45915.1}.
SEQUENCE 209 AA; 22496 MW; DBB357FC44DBDD89 CRC64;
MFINRWLFST NHKDIGTLYL LFGAWAGMVG TALSLLIRAE LGQPGTLLGD DQIYNVIVTA
HAFVMIFFMV MPIMIGGFGN WLVPLMIGAP DMAFPRMNNM SFWLLPPSFL LLLASSMIEA
GAGTGWTVYP PLAGNLAHAG ASVDLTIFSL HLAGVSSILG AINFITTIIN MKPPALSQYQ
TPLFVWSVLI TAVLLLLALP VLAAGITML


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