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Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Fragment)

 A0A1U8XVY8_9CHON        Unreviewed;       194 AA.
A0A1U8XVY8;
07-JUN-2017, integrated into UniProtKB/TrEMBL.
07-JUN-2017, sequence version 1.
23-MAY-2018, entry version 5.
RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
Flags: Fragment;
Name=COI {ECO:0000313|EMBL:ALR85756.1};
Squalus blainville (longnose spurdog).
Mitochondrion {ECO:0000313|EMBL:ALR85756.1}.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
Elasmobranchii; Squalimorphii; Squaliformes; Squalidae; Squalus.
NCBI_TaxID=934694 {ECO:0000313|EMBL:ALR85756.1};
[1] {ECO:0000313|EMBL:ALR85756.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Sbl_BAL01 {ECO:0000313|EMBL:ALR85731.1},
Sbl_BAL02 {ECO:0000313|EMBL:ALR85732.1},
Sbl_BAL03 {ECO:0000313|EMBL:ALR85733.1},
Sbl_BAL04 {ECO:0000313|EMBL:ALR85734.1},
Sbl_BAL05 {ECO:0000313|EMBL:ALR85735.1},
Sbl_CRE965 {ECO:0000313|EMBL:ALR85736.1},
Sbl_CRE966 {ECO:0000313|EMBL:ALR85737.1},
Sbl_CRE968 {ECO:0000313|EMBL:ALR85738.1},
Sbl_CRE969 {ECO:0000313|EMBL:ALR85739.1},
Sbl_CRE970 {ECO:0000313|EMBL:ALR85740.1},
Sbl_CRE971 {ECO:0000313|EMBL:ALR85741.1},
Sbl_CRE972 {ECO:0000313|EMBL:ALR85742.1},
Sbl_CRE974 {ECO:0000313|EMBL:ALR85743.1},
Sbl_CRE975 {ECO:0000313|EMBL:ALR85744.1},
Sbl_CRE976 {ECO:0000313|EMBL:ALR85745.1},
Sbl_CRE978 {ECO:0000313|EMBL:ALR85746.1},
Sbl_CRE979 {ECO:0000313|EMBL:ALR85747.1},
Sbl_CRE982 {ECO:0000313|EMBL:ALR85749.1},
Sbl_CRE983 {ECO:0000313|EMBL:ALR85750.1},
Sbl_CRE984 {ECO:0000313|EMBL:ALR85751.1},
Sbl_CRE985 {ECO:0000313|EMBL:ALR85752.1},
Sbl_CRE986 {ECO:0000313|EMBL:ALR85753.1},
Sbl_CYC797 {ECO:0000313|EMBL:ALR85754.1},
Sbl_CYC798 {ECO:0000313|EMBL:ALR85755.1},
Sbl_ION1005 {ECO:0000313|EMBL:ALR85756.1},
Sbl_ION1008 {ECO:0000313|EMBL:ALR85757.1},
Sbl_ION1011 {ECO:0000313|EMBL:ALR85758.1},
Sbl_ION1014 {ECO:0000313|EMBL:ALR85759.1},
Sbl_ION1015 {ECO:0000313|EMBL:ALR85760.1},
Sbl_ION1017 {ECO:0000313|EMBL:ALR85761.1},
Sbl_ION1018 {ECO:0000313|EMBL:ALR85762.1},
Sbl_ION1021 {ECO:0000313|EMBL:ALR85763.1},
Sbl_ION1025 {ECO:0000313|EMBL:ALR85764.1},
Sbl_ION1026 {ECO:0000313|EMBL:ALR85765.1},
Sbl_ION1027 {ECO:0000313|EMBL:ALR85766.1},
Sbl_ION1030 {ECO:0000313|EMBL:ALR85767.1},
Sbl_ION1031 {ECO:0000313|EMBL:ALR85768.1},
Sbl_ION1032 {ECO:0000313|EMBL:ALR85769.1},
Sbl_ION1033 {ECO:0000313|EMBL:ALR85770.1},
Sbl_ION1034 {ECO:0000313|EMBL:ALR85771.1},
Sbl_ION1035 {ECO:0000313|EMBL:ALR85772.1},
Sbl_ION1036 {ECO:0000313|EMBL:ALR85773.1},
Sbl_ION1037 {ECO:0000313|EMBL:ALR85774.1},
Sbl_ION1039 {ECO:0000313|EMBL:ALR85775.1},
Sbl_ION1042 {ECO:0000313|EMBL:ALR85776.1},
Sbl_ION1043 {ECO:0000313|EMBL:ALR85777.1},
Sbl_ION1044 {ECO:0000313|EMBL:ALR85778.1},
Sbl_ION1045 {ECO:0000313|EMBL:ALR85779.1},
Sbl_ION1046 {ECO:0000313|EMBL:ALR85780.1},
Sbl_ION1047 {ECO:0000313|EMBL:ALR85781.1},
Sbl_ION1050 {ECO:0000313|EMBL:ALR85782.1},
Sbl_ION1051 {ECO:0000313|EMBL:ALR85783.1},
Sbl_ION989 {ECO:0000313|EMBL:ALR85785.1},
Sbl_ION990 {ECO:0000313|EMBL:ALR85786.1},
Sbl_ION994 {ECO:0000313|EMBL:ALR85787.1},
Sbl_ION995 {ECO:0000313|EMBL:ALR85784.1},
Sbl_LIB359 {ECO:0000313|EMBL:ALR85788.1},
Sbl_LIB366 {ECO:0000313|EMBL:ALR85789.1},
Sbl_LIB367 {ECO:0000313|EMBL:ALR85790.1},
Sbl_LIB368 {ECO:0000313|EMBL:ALR85791.1},
Sbl_LIB369 {ECO:0000313|EMBL:ALR85792.1},
Sbl_LIB370 {ECO:0000313|EMBL:ALR85793.1},
Sbl_LIB372 {ECO:0000313|EMBL:ALR85794.1},
Sbl_LIB376 {ECO:0000313|EMBL:ALR85795.1},
Sbl_LIB377 {ECO:0000313|EMBL:ALR85796.1},
Sbl_LIB381 {ECO:0000313|EMBL:ALR85797.1},
Sbl_LIB382 {ECO:0000313|EMBL:ALR85798.1},
Sbl_LIB383 {ECO:0000313|EMBL:ALR85799.1},
Sbl_LIB385 {ECO:0000313|EMBL:ALR85800.1},
Sbl_LIB386 {ECO:0000313|EMBL:ALR85801.1},
Sbl_LIB389 {ECO:0000313|EMBL:ALR85802.1},
Sbl_LIB390 {ECO:0000313|EMBL:ALR85803.1},
Sbl_LIB393 {ECO:0000313|EMBL:ALR85804.1},
Sbl_LIB394 {ECO:0000313|EMBL:ALR85805.1},
Sbl_LIB395 {ECO:0000313|EMBL:ALR85806.1},
Sbl_LIB398 {ECO:0000313|EMBL:ALR85807.1},
Sbl_LIB399 {ECO:0000313|EMBL:ALR85808.1},
Sbl_LIB476 {ECO:0000313|EMBL:ALR85809.1},
Sbl_nAEG660 {ECO:0000313|EMBL:ALR85810.1},
Sbl_nAEG664 {ECO:0000313|EMBL:ALR85811.1},
Sbl_nAEG666 {ECO:0000313|EMBL:ALR85812.1},
Sbl_nAEG667 {ECO:0000313|EMBL:ALR85813.1},
Sbl_nAEG829 {ECO:0000313|EMBL:ALR85814.1},
Sbl_nAEG831 {ECO:0000313|EMBL:ALR85815.1},
Sbl_nAEG832 {ECO:0000313|EMBL:ALR85816.1},
Sbl_nAEG833 {ECO:0000313|EMBL:ALR85817.1},
Sbl_nAEG834 {ECO:0000313|EMBL:ALR85818.1},
Sbl_nAEG835 {ECO:0000313|EMBL:ALR85819.1},
Sbl_nAEG837 {ECO:0000313|EMBL:ALR85820.1},
Sbl_nAEG838 {ECO:0000313|EMBL:ALR85821.1},
Sbl_nAEG862 {ECO:0000313|EMBL:ALR85823.1},
Sbl_nAEG863 {ECO:0000313|EMBL:ALR85824.1},
Sbl_nAEG864 {ECO:0000313|EMBL:ALR85825.1},
Sbl_nAEG865 {ECO:0000313|EMBL:ALR85826.1},
Sbl_nAEG867 {ECO:0000313|EMBL:ALR85827.1},
Sbl_nAEG868 {ECO:0000313|EMBL:ALR85828.1},
Sbl_nAEG869 {ECO:0000313|EMBL:ALR85829.1},
Sbl_nAEG870 {ECO:0000313|EMBL:ALR85830.1},
Sbl_nAEG879 {ECO:0000313|EMBL:ALR85831.1},
Sbl_nAEG882 {ECO:0000313|EMBL:ALR85832.1},
Sbl_nAEG885 {ECO:0000313|EMBL:ALR85833.1},
Sbl_nAEG886 {ECO:0000313|EMBL:ALR85834.1},
Sbl_nAEG887 {ECO:0000313|EMBL:ALR85835.1},
Sbl_nAEG893 {ECO:0000313|EMBL:ALR85836.1}, and
Sbl_nAEG894 {ECO:0000313|EMBL:ALR85837.1};
Kousteni V., Kasapidis P., Kotoulas G., Megalofonou P.;
"Evidence of high genetic connectivity for the longnose spurdog
Squalus blainville in the Mediterranean Sea.";
Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
chain that catalyzes the reduction of oxygen to water. Subunits 1-
3 form the functional core of the enzyme complex. CO I is the
catalytic subunit of the enzyme. Electrons originating in
cytochrome c are transferred via the copper A center of subunit 2
and heme A of subunit 1 to the bimetallic center formed by heme A3
and copper B. {ECO:0000256|RuleBase:RU000369}.
-!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
-!- PATHWAY: Energy metabolism; oxidative phosphorylation.
{ECO:0000256|RuleBase:RU000369}.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
{ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
{ECO:0000256|RuleBase:RU000369}.
-!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
{ECO:0000256|RuleBase:RU000369}.
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EMBL; KU198487; ALR85731.1; -; Genomic_DNA.
EMBL; KU198488; ALR85732.1; -; Genomic_DNA.
EMBL; KU198489; ALR85733.1; -; Genomic_DNA.
EMBL; KU198490; ALR85734.1; -; Genomic_DNA.
EMBL; KU198491; ALR85735.1; -; Genomic_DNA.
EMBL; KU198492; ALR85736.1; -; Genomic_DNA.
EMBL; KU198493; ALR85737.1; -; Genomic_DNA.
EMBL; KU198494; ALR85738.1; -; Genomic_DNA.
EMBL; KU198495; ALR85739.1; -; Genomic_DNA.
EMBL; KU198496; ALR85740.1; -; Genomic_DNA.
EMBL; KU198497; ALR85741.1; -; Genomic_DNA.
EMBL; KU198498; ALR85742.1; -; Genomic_DNA.
EMBL; KU198499; ALR85743.1; -; Genomic_DNA.
EMBL; KU198500; ALR85744.1; -; Genomic_DNA.
EMBL; KU198501; ALR85745.1; -; Genomic_DNA.
EMBL; KU198502; ALR85746.1; -; Genomic_DNA.
EMBL; KU198503; ALR85747.1; -; Genomic_DNA.
EMBL; KU198505; ALR85749.1; -; Genomic_DNA.
EMBL; KU198506; ALR85750.1; -; Genomic_DNA.
EMBL; KU198507; ALR85751.1; -; Genomic_DNA.
EMBL; KU198508; ALR85752.1; -; Genomic_DNA.
EMBL; KU198509; ALR85753.1; -; Genomic_DNA.
EMBL; KU198510; ALR85754.1; -; Genomic_DNA.
EMBL; KU198511; ALR85755.1; -; Genomic_DNA.
EMBL; KU198512; ALR85756.1; -; Genomic_DNA.
EMBL; KU198513; ALR85757.1; -; Genomic_DNA.
EMBL; KU198514; ALR85758.1; -; Genomic_DNA.
EMBL; KU198515; ALR85759.1; -; Genomic_DNA.
EMBL; KU198516; ALR85760.1; -; Genomic_DNA.
EMBL; KU198517; ALR85761.1; -; Genomic_DNA.
EMBL; KU198518; ALR85762.1; -; Genomic_DNA.
EMBL; KU198519; ALR85763.1; -; Genomic_DNA.
EMBL; KU198520; ALR85764.1; -; Genomic_DNA.
EMBL; KU198521; ALR85765.1; -; Genomic_DNA.
EMBL; KU198522; ALR85766.1; -; Genomic_DNA.
EMBL; KU198523; ALR85767.1; -; Genomic_DNA.
EMBL; KU198524; ALR85768.1; -; Genomic_DNA.
EMBL; KU198525; ALR85769.1; -; Genomic_DNA.
EMBL; KU198526; ALR85770.1; -; Genomic_DNA.
EMBL; KU198527; ALR85771.1; -; Genomic_DNA.
EMBL; KU198528; ALR85772.1; -; Genomic_DNA.
EMBL; KU198529; ALR85773.1; -; Genomic_DNA.
EMBL; KU198530; ALR85774.1; -; Genomic_DNA.
EMBL; KU198531; ALR85775.1; -; Genomic_DNA.
EMBL; KU198532; ALR85776.1; -; Genomic_DNA.
EMBL; KU198533; ALR85777.1; -; Genomic_DNA.
EMBL; KU198534; ALR85778.1; -; Genomic_DNA.
EMBL; KU198535; ALR85779.1; -; Genomic_DNA.
EMBL; KU198536; ALR85780.1; -; Genomic_DNA.
EMBL; KU198537; ALR85781.1; -; Genomic_DNA.
EMBL; KU198538; ALR85782.1; -; Genomic_DNA.
EMBL; KU198539; ALR85783.1; -; Genomic_DNA.
EMBL; KU198540; ALR85784.1; -; Genomic_DNA.
EMBL; KU198541; ALR85785.1; -; Genomic_DNA.
EMBL; KU198542; ALR85786.1; -; Genomic_DNA.
EMBL; KU198543; ALR85787.1; -; Genomic_DNA.
EMBL; KU198544; ALR85788.1; -; Genomic_DNA.
EMBL; KU198545; ALR85789.1; -; Genomic_DNA.
EMBL; KU198546; ALR85790.1; -; Genomic_DNA.
EMBL; KU198547; ALR85791.1; -; Genomic_DNA.
EMBL; KU198548; ALR85792.1; -; Genomic_DNA.
EMBL; KU198549; ALR85793.1; -; Genomic_DNA.
EMBL; KU198550; ALR85794.1; -; Genomic_DNA.
EMBL; KU198551; ALR85795.1; -; Genomic_DNA.
EMBL; KU198552; ALR85796.1; -; Genomic_DNA.
EMBL; KU198553; ALR85797.1; -; Genomic_DNA.
EMBL; KU198554; ALR85798.1; -; Genomic_DNA.
EMBL; KU198555; ALR85799.1; -; Genomic_DNA.
EMBL; KU198556; ALR85800.1; -; Genomic_DNA.
EMBL; KU198557; ALR85801.1; -; Genomic_DNA.
EMBL; KU198558; ALR85802.1; -; Genomic_DNA.
EMBL; KU198559; ALR85803.1; -; Genomic_DNA.
EMBL; KU198560; ALR85804.1; -; Genomic_DNA.
EMBL; KU198561; ALR85805.1; -; Genomic_DNA.
EMBL; KU198562; ALR85806.1; -; Genomic_DNA.
EMBL; KU198563; ALR85807.1; -; Genomic_DNA.
EMBL; KU198564; ALR85808.1; -; Genomic_DNA.
EMBL; KU198565; ALR85809.1; -; Genomic_DNA.
EMBL; KU198567; ALR85810.1; -; Genomic_DNA.
EMBL; KU198568; ALR85811.1; -; Genomic_DNA.
EMBL; KU198569; ALR85812.1; -; Genomic_DNA.
EMBL; KU198570; ALR85813.1; -; Genomic_DNA.
EMBL; KU198571; ALR85814.1; -; Genomic_DNA.
EMBL; KU198572; ALR85815.1; -; Genomic_DNA.
EMBL; KU198573; ALR85816.1; -; Genomic_DNA.
EMBL; KU198574; ALR85817.1; -; Genomic_DNA.
EMBL; KU198575; ALR85818.1; -; Genomic_DNA.
EMBL; KU198576; ALR85819.1; -; Genomic_DNA.
EMBL; KU198577; ALR85820.1; -; Genomic_DNA.
EMBL; KU198578; ALR85821.1; -; Genomic_DNA.
EMBL; KU198580; ALR85823.1; -; Genomic_DNA.
EMBL; KU198581; ALR85824.1; -; Genomic_DNA.
EMBL; KU198582; ALR85825.1; -; Genomic_DNA.
EMBL; KU198583; ALR85826.1; -; Genomic_DNA.
EMBL; KU198584; ALR85827.1; -; Genomic_DNA.
EMBL; KU198585; ALR85828.1; -; Genomic_DNA.
EMBL; KU198586; ALR85829.1; -; Genomic_DNA.
EMBL; KU198587; ALR85830.1; -; Genomic_DNA.
EMBL; KU198588; ALR85831.1; -; Genomic_DNA.
EMBL; KU198589; ALR85832.1; -; Genomic_DNA.
EMBL; KU198590; ALR85833.1; -; Genomic_DNA.
EMBL; KU198591; ALR85834.1; -; Genomic_DNA.
EMBL; KU198592; ALR85835.1; -; Genomic_DNA.
EMBL; KU198593; ALR85836.1; -; Genomic_DNA.
EMBL; KU198594; ALR85837.1; -; Genomic_DNA.
UniPathway; UPA00705; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
Gene3D; 1.20.210.10; -; 1.
InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
InterPro; IPR000883; Cyt_C_Oxase_1.
PANTHER; PTHR10422; PTHR10422; 1.
Pfam; PF00115; COX1; 1.
PRINTS; PR01165; CYCOXIDASEI.
SUPFAM; SSF81442; SSF81442; 1.
PROSITE; PS50855; COX1; 1.
3: Inferred from homology;
Copper {ECO:0000256|RuleBase:RU000369};
Electron transport {ECO:0000256|RuleBase:RU000369};
Heme {ECO:0000256|RuleBase:RU000369};
Iron {ECO:0000256|RuleBase:RU000369};
Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
Metal-binding {ECO:0000256|RuleBase:RU000369};
Mitochondrion {ECO:0000256|RuleBase:RU000369};
Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
Oxidoreductase {ECO:0000256|RuleBase:RU000369,
ECO:0000313|EMBL:ALR85756.1};
Respiratory chain {ECO:0000256|RuleBase:RU000369};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius};
Transport {ECO:0000256|RuleBase:RU000369}.
TRANSMEM 20 45 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 66 88 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 108 133 Helical. {ECO:0000256|SAM:Phobius}.
TRANSMEM 145 172 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 1 194 COX1. {ECO:0000259|PROSITE:PS50855}.
NON_TER 1 1 {ECO:0000313|EMBL:ALR85756.1}.
NON_TER 194 194 {ECO:0000313|EMBL:ALR85756.1}.
SEQUENCE 194 AA; 20663 MW; FA51E517B7ED4545 CRC64;
AELSQPGTLL GDDQIYNVIV TAHAFVMIFF MVMPVMIGGF GNWLVPLMIG APDMAFPRMN
NMSFWLLPPS LLLLLASAGV EAGAGTGWTV YPPLAGNMAH AGASVDLAIF SLHLAGISSI
LASINFITTI INMKPPAISQ YQTPLFVWSI LVTTVLLLLS LPVLAAAITM LLTDRNLNTT
FFDPAGGGDP ILYQ


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EIAAB10104 Cox7a2,Cox7a3,Cox7al,Cytochrome c oxidase subunit 7A2, mitochondrial,Cytochrome c oxidase subunit VIIa-L,Cytochrome c oxidase subunit VIIa-liver_heart,Rat,Rattus norvegicus
EIAAB10080 Bos taurus,Bovine,COX6A1,Cytochrome c oxidase polypeptide VIa-liver,Cytochrome c oxidase subunit 6A1, mitochondrial,Cytochrome c oxidase subunit SSG
EIAAB10103 Bos taurus,Bovine,COX7A2,COX7AL,Cytochrome c oxidase subunit 7A2, mitochondrial,Cytochrome c oxidase subunit VIIa-L,Cytochrome c oxidase subunit VIIa-liver_heart
EIAAB08759 Cox5b,Cytochrome c oxidase polypeptide Vb,Cytochrome c oxidase subunit 5B, mitochondrial,Cytochrome c oxidase subunit VIA*,Rat,Rattus norvegicus
EIAAB08746 COX IV-1,COX4,COX4I1,COXIV,Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit 4 isoform 1, mitochondrial,Cytochrome c oxidase subunit IV isoform 1,Oryctolagus cuniculus,Rabbit
EIAAB10092 COX VIb-2,Cox6b2,Cytochrome c oxidase subunit 6B2,Cytochrome c oxidase subunit VIb isoform 2,Cytochrome c oxidase subunit VIb, testis-specific isoform,Mouse,Mus musculus
EIAAB10095 Bos taurus,Bovine,COX VIb-2,COX6B2,Cytochrome c oxidase subunit 6B2,Cytochrome c oxidase subunit VIb isoform 2,Cytochrome c oxidase subunit VIb, testis-specific isoform
EIAAB10094 COX VIb-2,Cox6b2,Cytochrome c oxidase subunit 6B2,Cytochrome c oxidase subunit VIb isoform 2,Cytochrome c oxidase subunit VIb, testis-specific isoform,Rat,Rattus norvegicus


 

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