GENTAUR Molecular Products.

 E3P8C0_9CAEN            Unreviewed;       200 AA.
 E3P8C0;
 11-JAN-2011, integrated into UniProtKB/TrEMBL.
 11-JAN-2011, sequence version 1.
 25-OCT-2017, entry version 27.
 RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
          EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
 Flags: Fragment;
 Name=COI {ECO:0000313|EMBL:ACW83489.1};
 Maackia herderiana.
 Mitochondrion {ECO:0000313|EMBL:ACW83489.1}.
 Eukaryota; Metazoa; Lophotrochozoa; Mollusca; Gastropoda;
 Caenogastropoda; Hypsogastropoda; Littorinimorpha; Rissooidea;
 Baicaliidae; Maackia.
 NCBI_TaxID=577130 {ECO:0000313|EMBL:ACW83489.1};
 [1] {ECO:0000313|EMBL:ACW83489.1}
 NUCLEOTIDE SEQUENCE.
 PubMed=20969796; DOI=10.1186/1471-2148-10-320;
 Fazalova V., Nevado B., Peretolchina T., Petunina J., Sherbakov D.;
 "When environmental changes do not cause geographic separation of
 fauna: differential responses of Baikalian invertebrates.";
 BMC Evol. Biol. 10:320-320(2010).
 -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
     chain that catalyzes the reduction of oxygen to water. Subunits 1-
     3 form the functional core of the enzyme complex. CO I is the
     catalytic subunit of the enzyme. Electrons originating in
     cytochrome c are transferred via the copper A center of subunit 2
     and heme A of subunit 1 to the bimetallic center formed by heme A3
     and copper B. {ECO:0000256|RuleBase:RU000369}.
 -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) + 4 H(+) = 4
     ferricytochrome c + 2 H(2)O. {ECO:0000256|RuleBase:RU000369}.
 -!- PATHWAY: Energy metabolism; oxidative phosphorylation.
     {ECO:0000256|RuleBase:RU000369}.
 -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
     {ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
     {ECO:0000256|RuleBase:RU000369}.
 -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
     {ECO:0000256|RuleBase:RU000369}.
 -----------------------------------------------------------------------
 Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
 Distributed under the Creative Commons Attribution-NoDerivs License
 -----------------------------------------------------------------------
 EMBL; FJ749204; ACW83489.1; -; Genomic_DNA.
 UniPathway; UPA00705; -.
 GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
 GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
 GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
 GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
 GO; GO:0020037; F:heme binding; IEA:InterPro.
 GO; GO:0005506; F:iron ion binding; IEA:InterPro.
 GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
 GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
 Gene3D; 1.20.210.10; -; 1.
 InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
 InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
 InterPro; IPR000883; Cyt_C_Oxase_1.
 PANTHER; PTHR10422; PTHR10422; 1.
 Pfam; PF00115; COX1; 1.
 PRINTS; PR01165; CYCOXIDASEI.
 SUPFAM; SSF81442; SSF81442; 1.
 PROSITE; PS50855; COX1; 1.
 3: Inferred from homology;
 Copper {ECO:0000256|RuleBase:RU000369};
 Electron transport {ECO:0000256|RuleBase:RU000369};
 Heme {ECO:0000256|RuleBase:RU000369};
 Iron {ECO:0000256|RuleBase:RU000369};
 Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
 Metal-binding {ECO:0000256|RuleBase:RU000369};
 Mitochondrion {ECO:0000256|RuleBase:RU000369};
 Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
 Oxidoreductase {ECO:0000256|RuleBase:RU000369};
 Respiratory chain {ECO:0000256|RuleBase:RU000369};
 Signal {ECO:0000256|SAM:SignalP};
 Transmembrane {ECO:0000256|SAM:Phobius};
 Transmembrane helix {ECO:0000256|SAM:Phobius};
 Transport {ECO:0000256|RuleBase:RU000369}.
 SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
 CHAIN        20    200       Cytochrome c oxidase subunit 1.
                              {ECO:0000256|SAM:SignalP}.
                              /FTId=PRO_5003178419.
 TRANSMEM     35     60       Helical. {ECO:0000256|SAM:Phobius}.
 TRANSMEM     81    103       Helical. {ECO:0000256|SAM:Phobius}.
 TRANSMEM    123    148       Helical. {ECO:0000256|SAM:Phobius}.
 TRANSMEM    160    187       Helical. {ECO:0000256|SAM:Phobius}.
 DOMAIN        1    200       COX1. {ECO:0000259|PROSITE:PS50855}.
 NON_TER       1      1       {ECO:0000313|EMBL:ACW83489.1}.
 NON_TER     200    200       {ECO:0000313|EMBL:ACW83489.1}.
 SEQUENCE   200 AA;  21509 MW;  2B921BEC7F5FB282 CRC64;
 MWSGLVGTAL SLLIRAELGQ PGALLGDDQL YNVIVTAHAF VMIFFLVMPM MIGGFGNWLI
 PLMLGAPDMA FPRLNNMSFW LLPPALLLLL SSAAVESGAG TGWTVYPPLA SNLADAGASV
 DLAIFSLHLA GVSSILGAVN FITTIINMRW RGMQFERLPL FVWSVKITAI LLLLSLPVLA
 GAITMLLTDR NFNTAFFDPA

Related products :