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Cytochrome c oxidase subunit 3 (Cytochrome c oxidase polypeptide III)

 COX3_EQUAS              Reviewed;         261 AA.
P92481;
15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
25-OCT-2017, entry version 90.
RecName: Full=Cytochrome c oxidase subunit 3;
AltName: Full=Cytochrome c oxidase polypeptide III;
Name=MT-CO3; Synonyms=COIII, COXIII, MTCO3;
Equus asinus (Donkey) (Equus africanus asinus).
Mitochondrion.
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9793;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=Kidney;
PubMed=8875857; DOI=10.1007/BF02337515;
Xu X., Gullberg A., Arnason U.;
"The complete mitochondrial DNA (mtDNA) of the donkey and mtDNA
comparisons among four closely related mammalian species-pairs.";
J. Mol. Evol. 43:438-446(1996).
-!- FUNCTION: Subunits I, II and III form the functional core of the
enzyme complex.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
Multi-pass membrane protein {ECO:0000250}.
-!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 3 family.
{ECO:0000305}.
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EMBL; X97337; CAA66020.1; -; Genomic_DNA.
PIR; T11369; T11369.
RefSeq; NP_007387.1; NC_001788.1.
ProteinModelPortal; P92481; -.
SMR; P92481; -.
GeneID; 808054; -.
KEGG; eai:808054; -.
CTD; 4514; -.
HOVERGEN; HBG016686; -.
KO; K02262; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO; GO:0045277; C:respiratory chain complex IV; ISS:UniProtKB.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
GO; GO:0019646; P:aerobic electron transport chain; IEA:InterPro.
GO; GO:0008535; P:respiratory chain complex IV assembly; ISS:UniProtKB.
CDD; cd01665; Cyt_c_Oxidase_III; 1.
Gene3D; 1.20.120.80; -; 1.
InterPro; IPR024791; Cyt_c/ubiquinol_Oxase_su3.
InterPro; IPR033945; Cyt_c_oxase_su3_dom.
InterPro; IPR000298; Cyt_c_oxidase-like_su3.
InterPro; IPR035973; Cyt_c_oxidase_su3-like_sf.
InterPro; IPR013833; Cyt_c_oxidase_su3_a-hlx.
PANTHER; PTHR11403; PTHR11403; 1.
Pfam; PF00510; COX3; 1.
SUPFAM; SSF81452; SSF81452; 1.
PROSITE; PS50253; COX3; 1.
3: Inferred from homology;
Membrane; Mitochondrion; Mitochondrion inner membrane; Transmembrane;
Transmembrane helix.
CHAIN 1 261 Cytochrome c oxidase subunit 3.
/FTId=PRO_0000183772.
TRANSMEM 31 51 Helical. {ECO:0000255}.
TRANSMEM 81 101 Helical. {ECO:0000255}.
TRANSMEM 127 147 Helical. {ECO:0000255}.
TRANSMEM 159 179 Helical. {ECO:0000255}.
TRANSMEM 197 217 Helical. {ECO:0000255}.
TRANSMEM 239 259 Helical. {ECO:0000255}.
SEQUENCE 261 AA; 29761 MW; EB33C3F0EBE40769 CRC64;
MTHQTHAYHM VNPSPWPLTG ALSALLMTSG LAMWFHFNST LLLALGLLTN ILTMYQWWRD
IIRESTFQGH HTSIVQKGLR YGMILFIISE VFFFSGFFWA FYHSSLAPTP ELGGCWPPTG
IHPLNPLEVP LLNTSVLLAS GVSITWAHHS LMEGNRKNML QGLFITISLG VYFTLLQASE
YYEASFTISD GVYGSTFFVA TGFHGLHVII GSTFLIVCFL RQLKFHFTSS HHFGFEAAAW
YWHFVDVVWL FLYVSIYWWG S


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