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Cytochrome c oxidase subunit 8A, mitochondrial (Cytochrome c oxidase polypeptide VIII-liver/heart) (Cytochrome c oxidase subunit 8-2)

 COX8A_SAISC             Reviewed;          69 AA.
Q863G5;
16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
01-JUN-2003, sequence version 1.
25-OCT-2017, entry version 58.
RecName: Full=Cytochrome c oxidase subunit 8A, mitochondrial;
AltName: Full=Cytochrome c oxidase polypeptide VIII-liver/heart;
AltName: Full=Cytochrome c oxidase subunit 8-2;
Flags: Precursor;
Name=COX8A; Synonyms=COX8, COX8L;
Saimiri sciureus (Common squirrel monkey).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Platyrrhini; Cebidae; Saimiriinae; Saimiri.
NCBI_TaxID=9521;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=12716970; DOI=10.1073/pnas.0931463100;
Goldberg A., Wildman D.E., Schmidt T.R., Huttemann M., Goodman M.,
Weiss M.L., Grossman L.I.;
"Adaptive evolution of cytochrome c oxidase subunit VIII in anthropoid
primates.";
Proc. Natl. Acad. Sci. U.S.A. 100:5873-5878(2003).
-!- FUNCTION: This protein is one of the nuclear-coded polypeptide
chains of cytochrome c oxidase, the terminal oxidase in
mitochondrial electron transport.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane.
-!- SIMILARITY: Belongs to the cytochrome c oxidase VIII family.
{ECO:0000305}.
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EMBL; AY254821; AAP32252.1; -; mRNA.
ProteinModelPortal; Q863G5; -.
SMR; Q863G5; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:InterPro.
Gene3D; 4.10.81.10; -; 1.
InterPro; IPR003205; Cyt_c_oxidase_su8.
InterPro; IPR036548; Cyt_c_oxidase_su8_sf.
PANTHER; PTHR16717; PTHR16717; 1.
Pfam; PF02285; COX8; 1.
SUPFAM; SSF81431; SSF81431; 1.
3: Inferred from homology;
Membrane; Mitochondrion; Mitochondrion inner membrane;
Transit peptide; Transmembrane; Transmembrane helix.
TRANSIT 1 25 Mitochondrion. {ECO:0000250}.
CHAIN 26 69 Cytochrome c oxidase subunit 8A,
mitochondrial.
/FTId=PRO_0000006196.
TOPO_DOM 26 36 Mitochondrial matrix. {ECO:0000250}.
TRANSMEM 37 60 Helical. {ECO:0000250}.
TOPO_DOM 61 69 Mitochondrial intermembrane.
{ECO:0000250}.
SEQUENCE 69 AA; 7539 MW; EBE9775D463C9E41 CRC64;
MSVLTPLLLR GLTGSARRLP VPRAQVHSMP PEQKLGVLEL AIGFTSCLVT FLLPAGWILS
HLDSYKKRG


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