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Cytochrome c oxidase subunit 8C, mitochondrial (Cytochrome c oxidase polypeptide 8 isoform 3) (Cytochrome c oxidase polypeptide VIII isoform 3) (COX VIII-3) (Cytochrome c oxidase subunit 8-3)

 COX8C_RAT               Reviewed;          72 AA.
Q7TNN2;
16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
01-OCT-2003, sequence version 1.
12-SEP-2018, entry version 90.
RecName: Full=Cytochrome c oxidase subunit 8C, mitochondrial;
AltName: Full=Cytochrome c oxidase polypeptide 8 isoform 3;
AltName: Full=Cytochrome c oxidase polypeptide VIII isoform 3;
Short=COX VIII-3;
AltName: Full=Cytochrome c oxidase subunit 8-3;
Flags: Precursor;
Name=Cox8c;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=12909344; DOI=10.1016/S0378-1119(03)00604-8;
Huettemann M., Schmidt T.R., Grossman L.I.;
"A third isoform of cytochrome c oxidase subunit VIII is present in
mammals.";
Gene 312:95-102(2003).
-!- FUNCTION: This protein is one of the nuclear-coded polypeptide
chains of cytochrome c oxidase, the terminal oxidase in
mitochondrial electron transport.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane.
-!- SIMILARITY: Belongs to the cytochrome c oxidase VIII family.
{ECO:0000305}.
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EMBL; AY161005; AAO26194.1; -; mRNA.
RefSeq; NP_898878.1; NM_183055.1.
UniGene; Rn.98192; -.
ProteinModelPortal; Q7TNN2; -.
STRING; 10116.ENSRNOP00000047295; -.
PaxDb; Q7TNN2; -.
Ensembl; ENSRNOT00000052296; ENSRNOP00000047295; ENSRNOG00000031106.
GeneID; 360229; -.
KEGG; rno:360229; -.
UCSC; RGD:727840; rat.
CTD; 341947; -.
RGD; 727840; Cox8c.
GeneTree; ENSGT00390000012036; -.
HOGENOM; HOG000111895; -.
InParanoid; Q7TNN2; -.
KO; K02273; -.
OMA; HSESPQN; -.
OrthoDB; EOG091G1A16; -.
PhylomeDB; Q7TNN2; -.
TreeFam; TF105070; -.
PRO; PR:Q7TNN2; -.
Proteomes; UP000002494; Chromosome 6.
Bgee; ENSRNOG00000031106; Expressed in 5 organ(s), highest expression level in testis.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IBA:GO_Central.
GO; GO:0004129; F:cytochrome-c oxidase activity; IBA:GO_Central.
GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; IBA:GO_Central.
GO; GO:1902600; P:proton transmembrane transport; IBA:GO_Central.
Gene3D; 4.10.81.10; -; 1.
InterPro; IPR003205; Cyt_c_oxidase_su8.
InterPro; IPR036548; Cyt_c_oxidase_su8_sf.
PANTHER; PTHR16717; PTHR16717; 1.
Pfam; PF02285; COX8; 1.
SUPFAM; SSF81431; SSF81431; 1.
3: Inferred from homology;
Complete proteome; Membrane; Mitochondrion;
Mitochondrion inner membrane; Reference proteome; Transit peptide;
Transmembrane; Transmembrane helix.
TRANSIT 1 29 Mitochondrion. {ECO:0000250}.
CHAIN 30 72 Cytochrome c oxidase subunit 8C,
mitochondrial.
/FTId=PRO_0000006202.
TOPO_DOM 30 40 Mitochondrial matrix. {ECO:0000250}.
TRANSMEM 41 64 Helical. {ECO:0000250}.
TOPO_DOM 65 72 Mitochondrial intermembrane.
{ECO:0000250}.
SEQUENCE 72 AA; 8073 MW; 298553EED9F236EB CRC64;
MSRLLQFCSS LLRHRVVLFS KPGHSGRLSH SESPQNQVLT PTESVVGIVV FFATFFIPAA
YVMSNLKFFK GE


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