Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)

 IL2RG_CANLF             Reviewed;         373 AA.
P40321;
01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
01-FEB-1995, sequence version 1.
23-MAY-2018, entry version 131.
RecName: Full=Cytokine receptor common subunit gamma;
AltName: Full=Interleukin-2 receptor subunit gamma;
Short=IL-2 receptor subunit gamma;
Short=IL-2R subunit gamma;
Short=IL-2RG;
AltName: Full=gammaC;
AltName: Full=p64;
AltName: CD_antigen=CD132;
Flags: Precursor;
Name=IL2RG;
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Spleen;
PubMed=7829104; DOI=10.1006/geno.1994.1460;
Henthorn P.S., Somberg R.L., Fimiani V.M., Puck J.M., Patterson D.F.,
Felsburg P.J.;
"IL-2R gamma gene microdeletion demonstrates that canine X-linked
severe combined immunodeficiency is a homologue of the human
disease.";
Genomics 23:69-74(1994).
-!- FUNCTION: Common subunit for the receptors for a variety of
interleukins.
-!- SUBUNIT: The gamma subunit is common to the IL2, IL4, IL7, IL15,
IL21 and probably also the IL13 receptors. Interacts with SHB upon
interleukin stimulation (By similarity). {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
protein.
-!- DOMAIN: The WSXWS motif appears to be necessary for proper protein
folding and thereby efficient intracellular transport and cell-
surface receptor binding.
-!- DOMAIN: The box 1 motif is required for JAK interaction and/or
activation.
-!- DISEASE: Note=Defects in IL2RG are the cause of a canine X-linked
severe combined immunodeficiency.
-!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 5
subfamily. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; U04361; AAC48403.1; -; mRNA.
PIR; A55718; A55718.
RefSeq; NP_001003201.1; NM_001003201.1.
UniGene; Cfa.40115; -.
ProteinModelPortal; P40321; -.
SMR; P40321; -.
STRING; 9615.ENSCAFP00000041465; -.
PaxDb; P40321; -.
Ensembl; ENSCAFT00000049104; ENSCAFP00000041465; ENSCAFG00000028978.
GeneID; 403851; -.
KEGG; cfa:403851; -.
CTD; 3561; -.
VGNC; VGNC:41979; IL2RG.
eggNOG; ENOG410IGNI; Eukaryota.
eggNOG; ENOG4111N9N; LUCA.
GeneTree; ENSGT00510000048979; -.
HOVERGEN; HBG052111; -.
InParanoid; P40321; -.
KO; K05070; -.
OMA; CNQHSPY; -.
OrthoDB; EOG091G07RI; -.
TreeFam; TF333657; -.
Reactome; R-CFA-1266695; Interleukin-7 signaling.
Reactome; R-CFA-392451; G beta:gamma signalling through PI3Kgamma.
Reactome; R-CFA-5673001; RAF/MAP kinase cascade.
Reactome; R-CFA-6785807; Interleukin-4 and 13 signaling.
Reactome; R-CFA-8983432; Interleukin-15 signaling.
Reactome; R-CFA-8985947; Interleukin-9 signaling.
Reactome; R-CFA-9020558; Interleukin-2 signaling.
Reactome; R-CFA-9020958; Interleukin-21 signaling.
Reactome; R-CFA-912526; Interleukin receptor SHC signaling.
Proteomes; UP000002254; Chromosome X.
Bgee; ENSCAFG00000028978; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
CDD; cd00063; FN3; 1.
Gene3D; 2.60.40.10; -; 2.
InterPro; IPR003961; FN3_dom.
InterPro; IPR036116; FN3_sf.
InterPro; IPR003531; Hempt_rcpt_S_F1_CS.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR015321; TypeI_recpt_CBD.
Pfam; PF00041; fn3; 1.
Pfam; PF09240; IL6Ra-bind; 1.
SMART; SM00060; FN3; 1.
SUPFAM; SSF49265; SSF49265; 2.
PROSITE; PS50853; FN3; 1.
PROSITE; PS01355; HEMATOPO_REC_S_F1; 1.
2: Evidence at transcript level;
Complete proteome; Disulfide bond; Glycoprotein; Membrane;
Phosphoprotein; Receptor; Reference proteome; Signal; Transmembrane;
Transmembrane helix.
SIGNAL 1 22 {ECO:0000255}.
CHAIN 23 373 Cytokine receptor common subunit gamma.
/FTId=PRO_0000010865.
TOPO_DOM 23 261 Extracellular. {ECO:0000255}.
TRANSMEM 262 283 Helical. {ECO:0000255}.
TOPO_DOM 284 373 Cytoplasmic. {ECO:0000255}.
DOMAIN 156 253 Fibronectin type-III.
{ECO:0000255|PROSITE-ProRule:PRU00316}.
MOTIF 237 241 WSXWS motif.
MOTIF 285 293 Box 1 motif.
MOD_RES 291 291 Phosphothreonine.
{ECO:0000250|UniProtKB:P31785}.
CARBOHYD 24 24 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 71 71 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 75 75 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 84 84 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 159 159 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 164 164 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 249 249 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 62 72 {ECO:0000255}.
DISULFID 102 115 {ECO:0000255}.
SEQUENCE 373 AA; 42516 MW; 03A0DE1F8B089D8B CRC64;
MLKPPLPLRS LLFLQLSLLG VGLNSTVPMP NGNEDITPDF FLTATPSETL SVSSLPLPEV
QCFVFNVEYM NCTWNSSSEP RPTNLTLHYW YKNSNDDKVQ ECGHYLFSRE VTAGCWLQKE
EIHLYETFVV QLRDPREPRR QSTQKLKLQN LVIPWAPENL TLHNLSESQL ELSWSNRHLD
HCLEHVVQYR SDWDRSWTEQ SVDHRNSFSL PSVDGQKFYT FRVRSRYNPL CGSAQRWSEW
SHPIHWGSNT SKENPLFASE AVLIPLGSMG LIISLICVYY WLERSIPRIP TLKNLEDLVT
EYHGNFSAWS GVSKGLAESL QPDYSEWLCH VSEIPPKGGA PGEGPGGSPC SQHSPYWAPP
CYTLKPETGA LIP


Related products :

Catalog number Product name Quantity
EIAAB40072 Homo sapiens,Human,Signal sequence receptor subunit gamma,SSR3,SSR-gamma,Translocon-associated protein subunit gamma,TRAPG,TRAP-gamma
EIAAB40075 Mouse,Mus musculus,Signal sequence receptor subunit gamma,Ssr3,SSR-gamma,Translocon-associated protein subunit gamma,TRAP-gamma
EIAAB40074 Rat,Rattus norvegicus,Signal sequence receptor subunit gamma,Ssr3,SSR-gamma,Translocon-associated protein subunit gamma,TRAP-gamma
EIAAB40073 Bos taurus,Bovine,Signal sequence receptor subunit gamma,SSR3,SSR-gamma,Translocon-associated protein subunit gamma,TRAP-gamma
EIAAB14650 Fc-epsilon RI-gamma,FCER1G,FceRI gamma,High affinity immunoglobulin epsilon receptor subunit gamma,Homo sapiens,Human,IgE Fc receptor subunit gamma
EIAAB14653 Fce1g,Fc-epsilon RI-gamma,Fcer1g,FceRI gamma,High affinity immunoglobulin epsilon receptor subunit gamma,IgE Fc receptor subunit gamma,Mouse,Mus musculus
EIAAB14652 Fce1g,Fc-epsilon RI-gamma,Fcer1g,FceRI gamma,High affinity immunoglobulin epsilon receptor subunit gamma,IgE Fc receptor subunit gamma,Rat,Rattus norvegicus
EIAAB14654 Bos taurus,Bovine,Fc-epsilon RI-gamma,FCER1G,FceRI gamma,High affinity immunoglobulin epsilon receptor subunit gamma,IgE Fc receptor subunit gamma
EIAAB14651 Fc-epsilon RI-gamma,FCER1G,FceRI gamma,High affinity immunoglobulin epsilon receptor subunit gamma,IgE Fc receptor subunit gamma,Pig,Sus scrofa
E2207h Homo sapiens,Human,LAMB2,LAMC1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,Lamini
E2207h ELISA Homo sapiens,Human,LAMB2,LAMC1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma, 96T
U2207h CLIA Homo sapiens,Human,LAMB2,LAMC1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,L 96T
18-003-43894 Gamma-aminobutyric acid receptor subunit gamma-2 - GABA(A) receptor subunit gamma-2 Polyclonal 0.1 mg Protein A
EIAAB29619 Homo sapiens,Human,PAF acetylhydrolase 29 kDa subunit,PAF-AH 29 kDa subunit,PAFAH subunit gamma,PAF-AH subunit gamma,PAFAH1B3,PAFAHG,Platelet-activating factor acetylhydrolase IB subunit gamma
E2207m ELISA kit Lamb-2,Lamc1,Lamc-1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,Lamini 96T
E2207h ELISA kit Homo sapiens,Human,LAMB2,LAMC1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit g 96T
U2207h CLIA kit Homo sapiens,Human,LAMB2,LAMC1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit ga 96T
EIAAB29617 Bos taurus,Bovine,PAF acetylhydrolase 29 kDa subunit,PAF-AH 29 kDa subunit,PAFAH subunit gamma,PAF-AH subunit gamma,PAFAH1B3,PAFAHG,Platelet-activating factor acetylhydrolase IB subunit gamma
EIAAB29618 Mouse,Mus musculus,PAF acetylhydrolase 29 kDa subunit,PAF-AH 29 kDa subunit,PAFAH subunit gamma,PAF-AH subunit gamma,Pafah1b3,Pafahg,Platelet-activating factor acetylhydrolase IB subunit gamma
EIAAB37642 Amiloride-sensitive sodium channel subunit gamma,ENaCG,Epithelial Na(+) channel subunit gamma,Gamma-ENaC,Gamma-NaCH,Homo sapiens,Human,Nonvoltage-gated sodium channel 1 subunit gamma,SCNEG,SCNN1G
EIAAB37641 Amiloride-sensitive sodium channel subunit gamma,Epithelial Na(+) channel subunit gamma,Gamma-ENaC,Gamma-NaCH,Nonvoltage-gated sodium channel 1 subunit gamma,Oryctolagus cuniculus,Rabbit,SCNEG,SCNN1G
EIAAB37639 Amiloride-sensitive sodium channel subunit gamma,Epithelial Na(+) channel subunit gamma,Gamma-ENaC,Gamma-NaCH,Nonvoltage-gated sodium channel 1 subunit gamma,Rat,Rattus norvegicus,SCNEG,Scnn1g
EIAAB37640 Amiloride-sensitive sodium channel subunit gamma,Epithelial Na(+) channel subunit gamma,Gamma-ENaC,Gamma-NaCH,Mouse,Mus musculus,Nonvoltage-gated sodium channel 1 subunit gamma,SCNEG,Scnn1g
E2207m ELISA Lamb-2,Lamc1,Lamc-1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,Laminin-4 s 96T
U2207m CLIA kit Lamb-2,Lamc1,Lamc-1,Laminin B2 chain,Laminin subunit gamma-1,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,Laminin 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur