Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Cytosolic 5'-nucleotidase 3A (EC 3.1.3.5) (7-methylguanosine phosphate-specific 5'-nucleotidase) (7-methylguanosine nucleotidase) (EC 3.1.3.91) (Cytosolic 5'-nucleotidase 3) (Cytosolic 5'-nucleotidase III) (cN-III) (Pyrimidine 5'-nucleotidase 1) (P5'N-1) (P5N-1) (PN-I)

 5NT3A_CHICK             Reviewed;         331 AA.
Q5ZID6; Q802T3;
13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
14-NOV-2006, sequence version 3.
12-SEP-2018, entry version 98.
RecName: Full=Cytosolic 5'-nucleotidase 3A {ECO:0000250|UniProtKB:Q9H0P0};
EC=3.1.3.5 {ECO:0000250|UniProtKB:Q9H0P0};
AltName: Full=7-methylguanosine phosphate-specific 5'-nucleotidase {ECO:0000250|UniProtKB:Q9H0P0};
Short=7-methylguanosine nucleotidase;
EC=3.1.3.91 {ECO:0000250|UniProtKB:Q9H0P0};
AltName: Full=Cytosolic 5'-nucleotidase 3;
AltName: Full=Cytosolic 5'-nucleotidase III;
Short=cN-III;
AltName: Full=Pyrimidine 5'-nucleotidase 1;
Short=P5'N-1;
Short=P5N-1;
Short=PN-I;
Name=NT5C3A; Synonyms=NT5C3, PYN1; ORFNames=RCJMB04_27l2;
Gallus gallus (Chicken).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
Phasianidae; Phasianinae; Gallus.
NCBI_TaxID=9031;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF 46-85;
150-158; 220-243 AND 291-290, DEVELOPMENTAL STAGE, AND INDUCTION.
TISSUE=Erythrocyte;
PubMed=12907448; DOI=10.1182/blood-2002-11-3388;
Mass M., Simo E., Dragon S.;
"Erythroid pyrimidine 5'-nucleotidase: cloning, developmental
expression, and regulation by cAMP and in vivo hypoxia.";
Blood 102:4198-4205(2003).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=Blood;
Mass M., Dragon S.;
"Cloning and gene expression of pyrimidine 5'-nucleotidase in chick
embryonic erythrocytes.";
Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
STRAIN=CB; TISSUE=Bursa of Fabricius;
PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J.,
Fiedler P., Kutter S., Blagodatski A., Kostovska D., Koter M.,
Plachy J., Carninci P., Hayashizaki Y., Buerstedde J.-M.;
"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
function analysis.";
Genome Biol. 6:R6.1-R6.9(2005).
-!- FUNCTION: Nucleotidase which shows specific activity towards
cytidine monophosphate (CMP) and 7-methylguanosine monophosphate
(m(7)GMP). CMP seems to be the preferred substrate.
{ECO:0000250|UniProtKB:Q9H0P0}.
-!- CATALYTIC ACTIVITY: N(7)-methyl-GMP + H(2)O = N(7)-methyl-
guanosine + phosphate. {ECO:0000250|UniProtKB:Q9H0P0}.
-!- CATALYTIC ACTIVITY: A 5'-ribonucleotide + H(2)O = a ribonucleoside
+ phosphate. {ECO:0000250|UniProtKB:Q9D020}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=2;
IsoId=Q5ZID6-3; Sequence=Displayed;
Name=1;
IsoId=Q5ZID6-1; Sequence=VSP_021564;
-!- DEVELOPMENTAL STAGE: Expressed at low levels until E13 and the
expression rises transiently between E13 and E16.
{ECO:0000269|PubMed:12907448}.
-!- INDUCTION: By norepinephrine/NE and adenosine which are released
by the embryo under hypoxic conditions. By stimulation of beta-
adrenergic/adenosine receptors in definitive red blood cells
(RBC). {ECO:0000269|PubMed:12907448}.
-!- SIMILARITY: Belongs to the pyrimidine 5'-nucleotidase family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AF548635; AAQ12342.1; -; mRNA.
EMBL; AJ496195; CAD42712.1; -; mRNA.
EMBL; AJ720848; CAG32507.1; -; mRNA.
RefSeq; NP_989767.1; NM_204436.2. [Q5ZID6-1]
RefSeq; XP_015136753.1; XM_015281267.1. [Q5ZID6-3]
RefSeq; XP_015136759.1; XM_015281273.1. [Q5ZID6-1]
UniGene; Gga.5031; -.
ProteinModelPortal; Q5ZID6; -.
SMR; Q5ZID6; -.
STRING; 9031.ENSGALP00000019881; -.
PaxDb; Q5ZID6; -.
Ensembl; ENSGALT00000062778; ENSGALP00000057361; ENSGALG00000031397. [Q5ZID6-1]
Ensembl; ENSGALT00000078633; ENSGALP00000054083; ENSGALG00000031397. [Q5ZID6-3]
GeneID; 395080; -.
KEGG; gga:395080; -.
CTD; 51251; -.
eggNOG; KOG3128; Eukaryota.
eggNOG; ENOG410ZQJ8; LUCA.
GeneTree; ENSGT00390000012959; -.
HOGENOM; HOG000244931; -.
HOVERGEN; HBG059750; -.
InParanoid; Q5ZID6; -.
KO; K01081; -.
OMA; HNVIDNC; -.
OrthoDB; EOG091G0BCN; -.
PhylomeDB; Q5ZID6; -.
TreeFam; TF314663; -.
Reactome; R-GGA-73621; Pyrimidine catabolism.
PRO; PR:Q5ZID6; -.
Proteomes; UP000000539; Chromosome 2.
Bgee; ENSGALG00000012192; Expressed in 10 organ(s), highest expression level in kidney.
GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO; GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.
GO; GO:0008253; F:5'-nucleotidase activity; ISS:UniProtKB.
GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO; GO:0051607; P:defense response to virus; IEA:Ensembl.
GO; GO:0009117; P:nucleotide metabolic process; IEA:UniProtKB-KW.
CDD; cd07504; HAD_5NT; 1.
Gene3D; 3.40.50.1000; -; 2.
InterPro; IPR036412; HAD-like_sf.
InterPro; IPR023214; HAD_sf.
InterPro; IPR006434; Pyrimidine_nucleotidase_eu.
Pfam; PF05822; UMPH-1; 1.
SFLD; SFLDG01128; C1.4:_5'-Nucleotidase_Like; 1.
SUPFAM; SSF56784; SSF56784; 1.
TIGRFAMs; TIGR01544; HAD-SF-IE; 1.
1: Evidence at protein level;
Alternative splicing; Complete proteome; Cytoplasm;
Direct protein sequencing; Hydrolase; Magnesium; Metal-binding;
Nucleotide metabolism; Nucleotide-binding; Reference proteome;
Transferase.
CHAIN 1 331 Cytosolic 5'-nucleotidase 3A.
/FTId=PRO_0000064386.
REGION 198 199 Substrate binding.
{ECO:0000250|UniProtKB:Q9D020}.
ACT_SITE 83 83 Nucleophile.
{ECO:0000250|UniProtKB:Q9D020}.
ACT_SITE 85 85 Proton donor.
{ECO:0000250|UniProtKB:Q9D020}.
METAL 83 83 Magnesium.
{ECO:0000250|UniProtKB:Q9D020}.
METAL 85 85 Magnesium; via carbonyl oxygen.
{ECO:0000250|UniProtKB:Q9D020}.
METAL 272 272 Magnesium.
{ECO:0000250|UniProtKB:Q9D020}.
BINDING 130 130 CMP. {ECO:0000250|UniProtKB:Q9W197}.
BINDING 130 130 N(7)-methyl-GMP.
{ECO:0000250|UniProtKB:Q9W197}.
BINDING 151 151 N(7)-methyl-GMP.
{ECO:0000250|UniProtKB:Q9W197}.
BINDING 247 247 Substrate.
{ECO:0000250|UniProtKB:Q9D020}.
VAR_SEQ 1 46 Missing (in isoform 1).
{ECO:0000303|PubMed:12907448,
ECO:0000303|Ref.2}.
/FTId=VSP_021564.
SEQUENCE 331 AA; 37370 MW; 7AE5CFE0F280224A CRC64;
MDRAAVAKMG AVASASVCAL VGGVVLAQYI FTMKKKTGRK TKIIEMMPEF QKKTVHIKDP
GRVEEIICGL IKGGAAKLQI ITDFDMTLSR FSYNGKRCPT CHNIIDNSKL ITEECRKKLL
QLKETYYAIE IDPALTIEEK YPYMVEWYNK SHALLIEQGL QKDKLAEVVR ESDVMLKEGY
ENFFDKLSEH NIPVFIFSAG IGDILEEVIH QAGVYHSNVK VVSNFMDFDE NGILKGFKGE
LIHVYNKHDG ALKNTEYFKQ LKDNSNIILL GDSQGDLSMA DGVANVEHIL KIGYLNDKVD
ELLEKYMDSY DIVLVKDESL EVANSILQKI L


Related products :

Catalog number Product name Quantity
EIAAB27998 5'(3')-deoxyribonucleotidase, cytosolic type,Cytosolic 5',3'-pyrimidine nucleotidase,Deoxy-5'-nucleotidase 1,Dnt1,dNT-1,Mouse,Mus musculus,Nt5c
EIAAB27999 5'(3')-deoxyribonucleotidase, cytosolic type,Cytosolic 5',3'-pyrimidine nucleotidase,Deoxy-5'-nucleotidase 1,DNT1,dNT-1,Homo sapiens,Human,NT5C,UMPH2
18-003-42157 Cytosolic 5'-nucleotidase III - EC 3.1.3.5; cN-III; Pyrimidine 5'-nucleotidase 1; P5'N-1; P5N-1; PN-I; Uridine 5'-monophosphate hydrolase 1; p36 Polyclonal 0.05 mg Aff Pur
10-288-22191F Cytosolic purine 5'-nucleotidase - EC 3.1.3.5; 5'-nucleotidase cytosolic II 0.1 mg
10-288-22191F Cytosolic purine 5'-nucleotidase - EC 3.1.3.5; 5'-nucleotidase cytosolic II 0.05 mg
EIAAB28000 5'-nucleotidase domain-containing protein 1,Cytosolic 5'-nucleotidase II-like protein 1,Mouse,Mus musculus,Nt5c2l1,Nt5dc1
E1327m Rat ELISA Kit FOR 7-methylguanosine phosphate-specific 5'-nucleotidase 96T
5NT3B_MOUSE Mouse ELISA Kit FOR 7-methylguanosine phosphate-specific 5'-nucleotidase 96T
E0104h ELISA kit 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Homo sapiens,Human,NT5,NT5E,NTE 96T
E0104h ELISA 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Homo sapiens,Human,NT5,NT5E,NTE 96T
U0104h CLIA 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Homo sapiens,Human,NT5,NT5E,NTE 96T
E0104r ELISA 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Nt5,Nt5e,Nte,Rat,Rattus norvegicus 96T
E0104m ELISA kit 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Mouse,Mus musculus,Nt5,Nt5e,Nte 96T
E0104m ELISA 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Mouse,Mus musculus,Nt5,Nt5e,Nte 96T
E0104r ELISA kit 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Nt5,Nt5e,Nte,Rat,Rattus norvegicus 96T
U0104r CLIA 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Nt5,Nt5e,Nte,Rat,Rattus norvegicus 96T
E0104b ELISA kit 5'-NT,5'-nucleotidase,Bos taurus,Bovine,Ecto-5'-nucleotidase,NT5,NT5E,NTE 96T
E0104b ELISA 5'-NT,5'-nucleotidase,Bos taurus,Bovine,Ecto-5'-nucleotidase,NT5,NT5E,NTE 96T
U0104b CLIA 5'-NT,5'-nucleotidase,Bos taurus,Bovine,Ecto-5'-nucleotidase,NT5,NT5E,NTE 96T
U0104m CLIA 5'-NT,5'-nucleotidase,Ecto-5'-nucleotidase,Mouse,Mus musculus,Nt5,Nt5e,Nte 96T
EIAAB28005 5'-nucleotidase domain-containing protein 3,Gnn,GRP94-neighboring nucleotidase,Mouse,Mus musculus,Nt5dc3
EIAAB28006 5'-nucleotidase domain-containing protein 3,GNN,GRP94-neighboring nucleotidase,Homo sapiens,Human,NT5DC3,TU12B1-TY
U0168h CLIA 5'-NT,5'-nucleotidase,ACPP,Ecto-5'-nucleotidase,Homo sapiens,Human,Prostatic acid phosphatase,Thiamine monophosphatase,TMPase 96T
E0168h ELISA 5'-NT,5'-nucleotidase,ACPP,Ecto-5'-nucleotidase,Homo sapiens,Human,Prostatic acid phosphatase,Thiamine monophosphatase,TMPase 96T
E0168h ELISA kit 5'-NT,5'-nucleotidase,ACPP,Ecto-5'-nucleotidase,Homo sapiens,Human,Prostatic acid phosphatase,Thiamine monophosphatase,TMPase 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur