Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

D(1B) dopamine receptor (D(5) dopamine receptor) (Dopamine D5 receptor)

 DRD5_RAT                Reviewed;         475 AA.
P25115;
01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
01-MAY-1992, sequence version 1.
10-MAY-2017, entry version 124.
RecName: Full=D(1B) dopamine receptor;
AltName: Full=D(5) dopamine receptor;
AltName: Full=Dopamine D5 receptor;
Name=Drd5;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Sprague-Dawley;
PubMed=1831904; DOI=10.1073/pnas.88.17.7491;
Tiberi M., Jarvie K.R., Silvia C., Falardeau P., Gingrich J.A.,
Godinot N., Bertrand L., Yang-Feng T.L., Fremeau R.T. Jr., Caron M.G.;
"Cloning, molecular characterization, and chromosomal assignment of a
gene encoding a second D1 dopamine receptor subtype: differential
expression pattern in rat brain compared with the D1A receptor.";
Proc. Natl. Acad. Sci. U.S.A. 88:7491-7495(1991).
-!- FUNCTION: Dopamine receptor whose activity is mediated by G
proteins which activate adenylyl cyclase.
-!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
-!- TISSUE SPECIFICITY: Brain, in the lateral mammillary nuclei, the
anterior pretectal nuclei, and several layers of the hippocampus.
-!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
{ECO:0000255|PROSITE-ProRule:PRU00521}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; M69118; AAA41072.1; -; Genomic_DNA.
PIR; A41271; A41271.
RefSeq; NP_036900.1; NM_012768.1.
UniGene; Rn.138110; -.
ProteinModelPortal; P25115; -.
STRING; 10116.ENSRNOP00000007074; -.
BindingDB; P25115; -.
ChEMBL; CHEMBL2281; -.
PaxDb; P25115; -.
PRIDE; P25115; -.
GeneID; 25195; -.
KEGG; rno:25195; -.
CTD; 1816; -.
RGD; 2523; Drd5.
eggNOG; KOG3656; Eukaryota.
eggNOG; ENOG410XRW9; LUCA.
HOGENOM; HOG000239242; -.
HOVERGEN; HBG106962; -.
InParanoid; P25115; -.
KO; K05840; -.
PhylomeDB; P25115; -.
PRO; PR:P25115; -.
Proteomes; UP000002494; Unplaced.
GO; GO:0030424; C:axon; IDA:RGD.
GO; GO:0031526; C:brush border membrane; IDA:RGD.
GO; GO:0030425; C:dendrite; IDA:RGD.
GO; GO:0043197; C:dendritic spine; IDA:RGD.
GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
GO; GO:0043025; C:neuronal cell body; IDA:RGD.
GO; GO:0004952; F:dopamine neurotransmitter receptor activity; IDA:MGI.
GO; GO:0001588; F:dopamine neurotransmitter receptor activity, coupled via Gs; IMP:RGD.
GO; GO:0008144; F:drug binding; IDA:RGD.
GO; GO:0001965; F:G-protein alpha-subunit binding; IPI:RGD.
GO; GO:0007191; P:adenylate cyclase-activating dopamine receptor signaling pathway; IMP:RGD.
GO; GO:0007189; P:adenylate cyclase-activating G-protein coupled receptor signaling pathway; IDA:MGI.
GO; GO:0007212; P:dopamine receptor signaling pathway; IDA:RGD.
GO; GO:0030336; P:negative regulation of cell migration; IMP:RGD.
GO; GO:0006469; P:negative regulation of protein kinase activity; IMP:RGD.
GO; GO:0060158; P:phospholipase C-activating dopamine receptor signaling pathway; IBA:GO_Central.
GO; GO:0010579; P:positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway; IEA:InterPro.
GO; GO:0030819; P:positive regulation of cAMP biosynthetic process; IMP:RGD.
GO; GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:RGD.
GO; GO:0001963; P:synaptic transmission, dopaminergic; IMP:RGD.
GO; GO:0008542; P:visual learning; IMP:RGD.
InterPro; IPR000497; Dopamine_D5_rcpt.
InterPro; IPR000929; Dopamine_rcpt.
InterPro; IPR000276; GPCR_Rhodpsn.
InterPro; IPR017452; GPCR_Rhodpsn_7TM.
Pfam; PF00001; 7tm_1; 1.
PRINTS; PR00566; DOPAMINED1BR.
PRINTS; PR00242; DOPAMINER.
PRINTS; PR00237; GPCRRHODOPSN.
SMART; SM01381; 7TM_GPCR_Srsx; 1.
PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
2: Evidence at transcript level;
Cell membrane; Complete proteome; Disulfide bond;
G-protein coupled receptor; Glycoprotein; Lipoprotein; Membrane;
Palmitate; Receptor; Reference proteome; Transducer; Transmembrane;
Transmembrane helix.
CHAIN 1 475 D(1B) dopamine receptor.
/FTId=PRO_0000069408.
TOPO_DOM 1 38 Extracellular. {ECO:0000255}.
TRANSMEM 39 64 Helical; Name=1. {ECO:0000255}.
TOPO_DOM 65 75 Cytoplasmic. {ECO:0000255}.
TRANSMEM 76 102 Helical; Name=2. {ECO:0000255}.
TOPO_DOM 103 111 Extracellular. {ECO:0000255}.
TRANSMEM 112 134 Helical; Name=3. {ECO:0000255}.
TOPO_DOM 135 153 Cytoplasmic. {ECO:0000255}.
TRANSMEM 154 179 Helical; Name=4. {ECO:0000255}.
TOPO_DOM 180 215 Extracellular. {ECO:0000255}.
TRANSMEM 216 240 Helical; Name=5. {ECO:0000255}.
TOPO_DOM 241 289 Cytoplasmic. {ECO:0000255}.
TRANSMEM 290 317 Helical; Name=6. {ECO:0000255}.
TOPO_DOM 318 335 Extracellular. {ECO:0000255}.
TRANSMEM 336 357 Helical; Name=7. {ECO:0000255}.
TOPO_DOM 358 475 Cytoplasmic. {ECO:0000255}.
LIPID 370 370 S-palmitoyl cysteine. {ECO:0000250}.
CARBOHYD 7 7 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 111 211 {ECO:0000255|PROSITE-ProRule:PRU00521}.
SEQUENCE 475 AA; 52831 MW; 4B0C004539540D82 CRC64;
MLPPGRNRTA QPARLGLQRQ LAQVDAPAGS ATPLGPAQVV TAGLLTLLIV WTLLGNVLVC
AAIVRSRHLR AKMTNIFIVS LAVSDLFVAL LVMPWKAVAE VAGYWPFGTF CDIWVAFDIM
CSTASILNLC IISVDRYWAI SRPFRYERKM TQRVALVMVG LAWTLSILIS FIPVQLNWHR
DKAGSQGQEG LLSNGTPWEE GWELEGRTEN CDSSLNRTYA ISSSLISFYI PVAIMIVTYT
RIYRIAQVQI RRISSLERAA EHAQSCRSRG AYEPDPSLRA SIKKETKVFK TLSMIMGVFV
CCWLPFFILN CMVPFCSSGD AEGPKTGFPC VSETTFDIFV WFGWANSSLN PIIYAFNADF
RKVFAQLLGC SHFCFRTPVQ TVNISNELIS YNQDTVFHKE IATAYVHMIP NAVSSGDREV
GEEEEEGPFD HMSQISPTTP DGDLAAESVW ELDCEEEVSL GKISPLTPNC FDKTA


Related products :

Catalog number Product name Quantity
EIAAB11914 D(1B) dopamine receptor,D(5) dopamine receptor,D1beta dopamine receptor,Dopamine D5 receptor,DRD1B,DRD1L2,DRD5,Homo sapiens,Human
EIAAB11910 D(2C) dopamine receptor,D(4) dopamine receptor,Dopamine D4 receptor,DRD4,Homo sapiens,Human
EIAAB11912 Bos taurus,Bovine,D(1B) dopamine receptor,D(5) dopamine receptor,Dopamine D5 receptor,DRD1B,DRD5
EIAAB11911 D(2C) dopamine receptor,D(4) dopamine receptor,Dopamine D4 receptor,Drd4,Mouse,Mus musculus
EIAAB11909 D(2C) dopamine receptor,D(4) dopamine receptor,Dopamine D4 receptor,Drd4,Rat,Rattus norvegicus
EIAAB11915 D(1B) dopamine receptor,D(5) dopamine receptor,Dopamine D5 receptor,Drd5,Mouse,Mus musculus
EIAAB11913 D(1B) dopamine receptor,D(5) dopamine receptor,Dopamine D5 receptor,Drd5,Rat,Rattus norvegicus
18-461-10678 D(1B) dopamine receptor - D(5) dopamine receptor; D1beta dopamine receptor Polyclonal 0.05 ml
E1299m ELISA D(1A) dopamine receptor,Dopamine D1 receptor,Drd1,Drd1a,Gpcr15,Mouse,Mus musculus 96T
E1299m ELISA kit D(1A) dopamine receptor,Dopamine D1 receptor,Drd1,Drd1a,Gpcr15,Mouse,Mus musculus 96T
U1299m CLIA D(1A) dopamine receptor,Dopamine D1 receptor,Drd1,Drd1a,Gpcr15,Mouse,Mus musculus 96T
E1299r ELISA D(1A) dopamine receptor,Dopamine D1 receptor,Drd1,Drd1a,Rat,Rattus norvegicus 96T
E0673h ELISA kit D(2) dopamine receptor,Dopamine D2 receptor,DRD2,Homo sapiens,Human 96T
E1299Rb ELISA D(1A) dopamine receptor,Dopamine D1 receptor,DRD1,Oryctolagus cuniculus,Rabbit 96T
E1299b ELISA kit Bos taurus,Bovine,D(1A) dopamine receptor,D1AR,Dopamine D1 receptor,DRD1 96T
E1299r ELISA kit D(1A) dopamine receptor,Dopamine D1 receptor,Drd1,Drd1a,Rat,Rattus norvegicus 96T
U1299r CLIA D(1A) dopamine receptor,Dopamine D1 receptor,Drd1,Drd1a,Rat,Rattus norvegicus 96T
U1299Rb CLIA D(1A) dopamine receptor,Dopamine D1 receptor,DRD1,Oryctolagus cuniculus,Rabbit 96T
U1299h CLIA D(1A) dopamine receptor,Dopamine D1 receptor,DRD1,Homo sapiens,Human 96T
18-783-77560 RABBIT ANTI HUMAN DOPAMINE RECEPTOR D2 & D3 (C-TERMINAL) - Dopamine D2 receptor Polyclonal 0.25 ml
E1299h ELISA kit D(1A) dopamine receptor,Dopamine D1 receptor,DRD1,Homo sapiens,Human 96T
U1299b CLIA Bos taurus,Bovine,D(1A) dopamine receptor,D1AR,Dopamine D1 receptor,DRD1 96T
E1299h ELISA D(1A) dopamine receptor,Dopamine D1 receptor,DRD1,Homo sapiens,Human 96T
U0673h CLIA D(2) dopamine receptor,Dopamine D2 receptor,DRD2,Homo sapiens,Human 96T
E0673h ELISA D(2) dopamine receptor,Dopamine D2 receptor,DRD2,Homo sapiens,Human 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur