Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

D-alanyl-D-alanine carboxypeptidase DacA (DD-carboxypeptidase) (DD-peptidase) (EC 3.4.16.4) (Penicillin-binding protein 5) (PBP-5)

 DACA_ECOL6              Reviewed;         403 AA.
P0AEB3; P04287; P77106;
20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
20-MAR-1987, sequence version 1.
07-JUN-2017, entry version 84.
RecName: Full=D-alanyl-D-alanine carboxypeptidase DacA;
Short=DD-carboxypeptidase;
Short=DD-peptidase;
EC=3.4.16.4;
AltName: Full=Penicillin-binding protein 5;
Short=PBP-5;
Flags: Precursor;
Name=dacA; OrderedLocusNames=c0722;
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
Enterobacteriaceae; Escherichia.
NCBI_TaxID=199310;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CFT073 / ATCC 700928 / UPEC;
PubMed=12471157; DOI=10.1073/pnas.252529799;
Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P.,
Rasko D., Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D.,
Mayhew G.F., Rose D.J., Zhou S., Schwartz D.C., Perna N.T.,
Mobley H.L.T., Donnenberg M.S., Blattner F.R.;
"Extensive mosaic structure revealed by the complete genome sequence
of uropathogenic Escherichia coli.";
Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
-!- FUNCTION: Removes C-terminal D-alanyl residues from sugar-peptide
cell wall precursors. {ECO:0000250}.
-!- CATALYTIC ACTIVITY: Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-
D-Ala. Also transpeptidation of peptidyl-alanyl moieties that are
N-acyl substituents of D-alanine.
-!- PATHWAY: Cell wall biogenesis; peptidoglycan biosynthesis.
-!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250};
Peripheral membrane protein {ECO:0000250}. Note=N-terminal lies in
the periplasmic space. {ECO:0000250}.
-!- SIMILARITY: Belongs to the peptidase S11 family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AE014075; AAN79195.1; -; Genomic_DNA.
RefSeq; WP_001092082.1; NC_004431.1.
ProteinModelPortal; P0AEB3; -.
SMR; P0AEB3; -.
STRING; 199310.c0722; -.
DrugBank; DB04647; BOC-GAMMA-D-GLU-L-LYS(CBZ)-D-BOROALA.
DrugBank; DB01147; Cloxacillin.
EnsemblBacteria; AAN79195; AAN79195; c0722.
KEGG; ecc:c0722; -.
eggNOG; ENOG4105DZ1; Bacteria.
eggNOG; COG1686; LUCA.
HOGENOM; HOG000086623; -.
KO; K07258; -.
OMA; LQNTHFQ; -.
BioCyc; ECOL199310:C0722-MONOMER; -.
UniPathway; UPA00219; -.
Proteomes; UP000001410; Chromosome.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:UniProtKB-EC.
GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniPathway.
GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
Gene3D; 2.60.410.10; -; 1.
InterPro; IPR012338; Beta-lactam/transpept-like.
InterPro; IPR015956; Peniciliin-bd_prot-assoc.
InterPro; IPR018044; Peptidase_S11.
InterPro; IPR012907; Peptidase_S11_C.
InterPro; IPR001967; Peptidase_S11_N.
Pfam; PF07943; PBP5_C; 1.
Pfam; PF00768; Peptidase_S11; 1.
PRINTS; PR00725; DADACBPTASE1.
SMART; SM00936; PBP5_C; 1.
SUPFAM; SSF56601; SSF56601; 1.
SUPFAM; SSF69189; SSF69189; 1.
3: Inferred from homology;
Carboxypeptidase; Cell inner membrane; Cell membrane; Cell shape;
Cell wall biogenesis/degradation; Complete proteome; Hydrolase;
Membrane; Peptidoglycan synthesis; Protease; Signal.
SIGNAL 1 29 {ECO:0000250}.
CHAIN 30 403 D-alanyl-D-alanine carboxypeptidase DacA.
/FTId=PRO_0000043392.
ACT_SITE 73 73 Acyl-ester intermediate. {ECO:0000250}.
ACT_SITE 76 76 Proton acceptor. {ECO:0000250}.
ACT_SITE 139 139 {ECO:0000250}.
BINDING 242 242 Substrate. {ECO:0000250}.
SEQUENCE 403 AA; 44444 MW; 7FAAB8E98452FF22 CRC64;
MNTIFSARIM KRLALTTALC TAFISAAHAD DLNIKTMIPG VPQIDAESYI LIDYNSGKVL
AEQNADVRRD PASLTKMMTS YVIGQAMKAG KFKETDLVTI GNDAWATGNP VFKGSSLMFL
KPGMQVPVSQ LIRGINLQSG NDACVAMADF AAGSQDAFVG LMNSYVNALG LKNTHFQTVH
GLDADGQYSS ARDMALIGQA LIRDVPNEYS IYKEKEFTFN GIRQLNRNGL LWDNSLNVDG
IKTGHTDKAG YNLVASATEG QMRLISAVMG GRTFKGREAE SKKLLTWGFR FFETVNPLKV
GKEFASEPVW FGDSDRASLG VDKDVYLTIP RGRMKDLKAS YVLNSSELHA PLQKNQVVGT
INFQLDGKTI EQRPLVVLQE IPEGNFFGKI IDYIKLMFHH WFG


Related products :

Catalog number Product name Quantity
20-272-191095 Carboxypeptidase B2 - Mouse monoclonal [15A10] to Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI; Plasma carboxypeptidase B; pCPB Monoclona 0.2 mg
EIAAB09070 ACBP,Carboxypeptidase N 83 kDa chain,Carboxypeptidase N large subunit,Carboxypeptidase N polypeptide 2,Carboxypeptidase N regulatory subunit,Carboxypeptidase N subunit 2,CPN2,Homo sapiens,Human
EIAAB05608 ACBP,Anaphylatoxin inactivator,Arginine carboxypeptidase,Carboxypeptidase N catalytic chain,Carboxypeptidase N polypeptide 1,Carboxypeptidase N small subunit,CPN,CPN1,Homo sapiens,Human,Kininase-1,Lys
EIAAB09069 Carboxypeptidase N 83 kDa chain,Carboxypeptidase N large subunit,Carboxypeptidase N polypeptide 2,Carboxypeptidase N regulatory subunit,Carboxypeptidase N subunit 2,Cpn2,Mouse,Mus musculus
20-272-191093 Carboxypeptidase B2 - Mouse monoclonal [13D5] to Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI; Plasma carboxypeptidase B; pCPB Monoclonal 0.2 mg
20-272-191097 Carboxypeptidase B2 - Mouse monoclonal [16C5] to Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI; Plasma carboxypeptidase B; pCPB Monoclonal 0.2 mg
20-272-191096 Carboxypeptidase B2 - Mouse monoclonal [19E2] to Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI; Plasma carboxypeptidase B; pCPB Monoclonal 0.2 mg
20-272-191094 Carboxypeptidase B2 - Mouse monoclonal [13H4] to Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI; Plasma carboxypeptidase B; pCPB Monoclonal 0.2 mg
20-272-191092 Carboxypeptidase B2 - Mouse monoclonal [13C3] to Carboxypeptidase B2; EC 3.4.17.20; Carboxypeptidase U; CPU; Thrombin-activable fibrinolysis inhibitor; TAFI; Plasma carboxypeptidase B; pCPB Monoclonal 0.2 mg
18-272-195322 Carboxypeptidase H - Rabbit polyclonal to Carboxypeptidase H; EC 3.4.17.10; CPE; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase Polyclonal 0.1 ml
18-272-195323 Carboxypeptidase H - Rabbit polyclonal to Carboxypeptidase H; EC 3.4.17.10; CPE; Carboxypeptidase H; CPH; Enkephalin convertase; Prohormone-processing carboxypeptidase Polyclonal 0.1 ml
orb90051 Rat Carboxypeptidase-B protein Recombinant Rat Carboxypeptidase-B is expressed in E.coli having Mw of 35kDa is purified by standard chromatography techniques. Recombinant Rat Carboxypeptidase-B is fre 5 mg
EIAAB05607 Bos taurus,Bovine,Carboxypeptidase N catalytic chain,Carboxypeptidase N polypeptide 1,Carboxypeptidase N small subunit,CPN,CPN1
EIAAB05606 Carboxypeptidase N catalytic chain,Carboxypeptidase N polypeptide 1,Carboxypeptidase N small subunit,CPN,Cpn1,Rat,Rattus norvegicus
EIAAB05609 Carboxypeptidase N catalytic chain,Carboxypeptidase N polypeptide 1,Carboxypeptidase N small subunit,CPN,Cpn1,Mouse,Mus musculus
EIAAB05600 Carboxypeptidase E,Carboxypeptidase H,CPE,CPE,CPH,Enkephalin convertase,Homo sapiens,Human,Prohormone-processing carboxypeptidase
U0615r CLIA Carboxypeptidase B2,Carboxypeptidase R,Carboxypeptidase U,Cpb2,CPR,CPU,Rat,Rattus norvegicus,TAFI,Thrombin-activable fibrinolysis inhibitor 96T
E0615r ELISA kit Carboxypeptidase B2,Carboxypeptidase R,Carboxypeptidase U,Cpb2,CPR,CPU,Rat,Rattus norvegicus,TAFI,Thrombin-activable fibrinolysis inhibitor 96T
E0615r ELISA Carboxypeptidase B2,Carboxypeptidase R,Carboxypeptidase U,Cpb2,CPR,CPU,Rat,Rattus norvegicus,TAFI,Thrombin-activable fibrinolysis inhibitor 96T
EIAAB05601 Bos taurus,Bovine,Carboxypeptidase E,Carboxypeptidase H,CPE,CPE,CPH,Enkephalin convertase,Prohormone-processing carboxypeptidase
EIAAB05603 Carboxypeptidase E,Carboxypeptidase H,CPE,Cpe,CPH,Enkephalin convertase,Prohormone-processing carboxypeptidase,Rat,Rattus norvegicus
EIAAB05602 Carboxypeptidase E,Carboxypeptidase H,CPE,Cpe,CPH,Enkephalin convertase,Mouse,Mus musculus,Prohormone-processing carboxypeptidase
E0615b ELISA Bos taurus,Bovine,Carboxypeptidase B2,Carboxypeptidase U,CPB2,CPU,pCPB,Plasma carboxypeptidase B,TAFI,Thrombin-activable fibrinolysis inhibitor 96T
U0615b CLIA Bos taurus,Bovine,Carboxypeptidase B2,Carboxypeptidase U,CPB2,CPU,pCPB,Plasma carboxypeptidase B,TAFI,Thrombin-activable fibrinolysis inhibitor 96T
E0615b ELISA kit Bos taurus,Bovine,Carboxypeptidase B2,Carboxypeptidase U,CPB2,CPU,pCPB,Plasma carboxypeptidase B,TAFI,Thrombin-activable fibrinolysis inhibitor 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur