Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Delta(7)-sterol 5(6)-desaturase erg32 (EC 1.14.19.20) (C-5 sterol desaturase erg32) (Ergosterol Delta(5,6) desaturase erg32) (Ergosterol biosynthesis protein 32) (Sterol-C5-desaturase erg32)

 ERG32_SCHPO             Reviewed;         329 AA.
O13666;
15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
01-JAN-1998, sequence version 1.
05-JUL-2017, entry version 130.
RecName: Full=Delta(7)-sterol 5(6)-desaturase erg32;
EC=1.14.19.20;
AltName: Full=C-5 sterol desaturase erg32;
AltName: Full=Ergosterol Delta(5,6) desaturase erg32;
AltName: Full=Ergosterol biosynthesis protein 32;
AltName: Full=Sterol-C5-desaturase erg32;
Name=erg32; ORFNames=pi075, SPBC27B12.03c;
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
Schizosaccharomycetes; Schizosaccharomycetales;
Schizosaccharomycetaceae; Schizosaccharomyces.
NCBI_TaxID=284812;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=972 / ATCC 24843;
PubMed=10620777;
DOI=10.1002/(SICI)1097-0061(20000115)16:1<71::AID-YEA505>3.0.CO;2-5;
Machida M., Yamazaki S., Kunihiro S., Tanaka T., Kushida N., Jinno K.,
Haikawa Y., Yamazaki J., Yamamoto S., Sekine M., Oguchi A., Nagai Y.,
Sakai M., Aoki K., Ogura K., Kudoh Y., Kikuchi H., Zhang M.Q.,
Yanagida M.;
"A 38 kb segment containing the cdc2 gene from the left arm of fission
yeast chromosome II: sequence analysis and characterization of the
genomic DNA and cDNAs encoded on the segment.";
Yeast 16:71-80(2000).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=972 / ATCC 24843;
PubMed=11859360; DOI=10.1038/nature724;
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M.,
Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A.,
Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G.,
Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K.,
James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J.,
Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C.,
Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E.,
Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S.,
Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K.,
Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S.,
Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B.,
Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S.,
Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D.,
Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R.,
Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B.,
Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S.,
Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M.,
Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G.,
Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J.,
Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L.,
Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J.,
Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.;
"The genome sequence of Schizosaccharomyces pombe.";
Nature 415:871-880(2002).
[3]
SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
PubMed=16823372; DOI=10.1038/nbt1222;
Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
Yoshida M.;
"ORFeome cloning and global analysis of protein localization in the
fission yeast Schizosaccharomyces pombe.";
Nat. Biotechnol. 24:841-847(2006).
[4]
FUNCTION.
PubMed=18310029; DOI=10.1099/mic.0.2007/011155-0;
Iwaki T., Iefuji H., Hiraga Y., Hosomi A., Morita T., Giga-Hama Y.,
Takegawa K.;
"Multiple functions of ergosterol in the fission yeast
Schizosaccharomyces pombe.";
Microbiology 154:830-841(2008).
-!- FUNCTION: Catalyzes the introduction of a C-5 double bond in the B
ring of ergosterol. Involved in the biosynthesis or ergosterol
which is important for plasma membrane structure and function and
for localization of plasma membrane proteins.
{ECO:0000269|PubMed:18310029}.
-!- CATALYTIC ACTIVITY: A Delta(7)-sterol + 2 ferrocytochrome b5 +
O(2) + 2 H(+) = a Delta(5,7)-sterol + 2 ferricytochrome b5 + 2
H(2)O. {ECO:0000250|UniProtKB:P32353}.
-!- COFACTOR:
Name=Fe cation; Xref=ChEBI:CHEBI:24875; Evidence={ECO:0000250};
-!- PATHWAY: Steroid metabolism; ergosterol biosynthesis; ergosterol
from zymosterol: step 3/5.
-!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
{ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
{ECO:0000269|PubMed:16823372}. Golgi apparatus membrane
{ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
{ECO:0000269|PubMed:16823372}.
-!- DOMAIN: The histidine box domains may contain the active site
and/or be involved in metal ion binding. {ECO:0000250}.
-!- SIMILARITY: Belongs to the sterol desaturase family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AB004539; BAA21457.1; -; Genomic_DNA.
EMBL; CU329671; CAA16898.1; -; Genomic_DNA.
PIR; T40027; T40027.
RefSeq; NP_001018791.2; NM_001021446.3.
MINT; MINT-4667052; -.
STRING; 4896.SPBC27B12.03c.1; -.
MaxQB; O13666; -.
PRIDE; O13666; -.
EnsemblFungi; SPBC27B12.03c.1; SPBC27B12.03c.1:pep; SPBC27B12.03c.
GeneID; 3361266; -.
KEGG; spo:SPBC27B12.03c; -.
EuPathDB; FungiDB:SPBC27B12.03c; -.
PomBase; SPBC27B12.03c; erg32.
HOGENOM; HOG000200579; -.
InParanoid; O13666; -.
KO; K00227; -.
OrthoDB; EOG092C3V4R; -.
PhylomeDB; O13666; -.
Reactome; R-SPO-6807047; Cholesterol biosynthesis via desmosterol.
Reactome; R-SPO-6807062; Cholesterol biosynthesis via lathosterol.
UniPathway; UPA00768; UER00762.
PRO; PR:O13666; -.
Proteomes; UP000002485; Chromosome II.
GO; GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
GO; GO:0005794; C:Golgi apparatus; IDA:PomBase.
GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO; GO:0030176; C:integral component of endoplasmic reticulum membrane; IC:PomBase.
GO; GO:0000248; F:C-5 sterol desaturase activity; ISO:PomBase.
GO; GO:0005506; F:iron ion binding; IEA:InterPro.
GO; GO:0006696; P:ergosterol biosynthetic process; IMP:PomBase.
InterPro; IPR006694; Fatty_acid_hydroxylase.
Pfam; PF04116; FA_hydroxylase; 1.
3: Inferred from homology;
Complete proteome; Endoplasmic reticulum; Golgi apparatus; Iron;
Lipid biosynthesis; Lipid metabolism; Membrane; Oxidoreductase;
Reference proteome; Steroid biosynthesis; Steroid metabolism;
Sterol biosynthesis; Sterol metabolism; Transmembrane;
Transmembrane helix.
CHAIN 1 329 Delta(7)-sterol 5(6)-desaturase erg32.
/FTId=PRO_0000117026.
TRANSMEM 67 87 Helical. {ECO:0000255}.
TRANSMEM 149 169 Helical. {ECO:0000255}.
TRANSMEM 210 230 Helical. {ECO:0000255}.
MOTIF 170 175 Histidine box-1.
MOTIF 183 187 Histidine box-2.
MOTIF 257 262 Histidine box-3.
SEQUENCE 329 AA; 39063 MW; C9DEF93732BC4BFA CRC64;
MDVVLQYADK YVFDTFYGKI AESFDSSSSF ANTAVNSTTL GLAEKVNFAI TSGLLDRNNV
WRQFTSLFLI TWIMGTLSYF LSASFAYYVY FDREEARRHP KFLKNQEHLE LMVALKNLPG
MAILTAPWFL AEIRGYGYVY DKLDEYGYFY LFFSIALFLL FSDFLIYWIH RALHHRWLYA
PLHKLHHKWI VPTPYSSHAF HYLDGYSQSL PYHMFPFFFP LNKYVYLLLF GSVNYWTVLI
HDGKYFSNNA VVNGAAHHAA HHMYFNYNYG QFFTLFDRLC SSYRQPDQEL FDAELRNEKL
QEQRIRFMET VQYTVEGKDD RTYASKKDN


Related products :

Catalog number Product name Quantity
EIAAB37453 C-5 sterol desaturase,Delta(7)-sterol 5-desaturase,Homo sapiens,Human,Lathosterol 5-desaturase,Lathosterol oxidase,SC5DL,Sterol-C5-desaturase
EIAAB37454 C-5 sterol desaturase,Delta(7)-sterol 5-desaturase,Lathosterol 5-desaturase,Lathosterol oxidase,Mouse,Mus musculus,Sc5d,Sc5dl,Sterol-C5-desaturase
CSB-EL020737HU Human sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like (SC5DL) ELISA kit, Species Human, Sample Type serum, plasma 96T
CSB-EL020737MO Mouse sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like (SC5DL) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
SC5DL SC5DL Gene sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
18-003-42290 Acyl-CoA desaturase - EC 1.14.19.1; Stearoyl-CoA desaturase; Fatty acid desaturase; Delta(9)-desaturase Polyclonal 0.1 mg Protein A
EIAAB14328 D5D,Delta(5) desaturase,Delta(5) fatty acid desaturase,Delta-5 desaturase,FADS1,FADSD5,Fatty acid desaturase 1,Homo sapiens,Human
EIAAB14332 D6D,Delta(6) desaturase,Delta(6) fatty acid desaturase,Delta-6 desaturase,FADS2,Fatty acid desaturase 2,Homo sapiens,Human
EIAAB14331 D6D,Delta(6) desaturase,Delta(6) fatty acid desaturase,Delta-6 desaturase,Fads2,Fadsd6,Fatty acid desaturase 2,Rat,Rattus norvegicus
EIAAB14330 D6D,Delta(6) desaturase,Delta(6) fatty acid desaturase,Delta-6 desaturase,Fads2,Fadsd2,Fatty acid desaturase 2,Mouse,Mus musculus
EIAAB14329 D5D,Delta(5) desaturase,Delta(5) fatty acid desaturase,Delta-5 desaturase,Fads1,Fatty acid desaturase 1,Rat,Rattus norvegicus
EIAAB14333 Bos taurus,Bovine,D6D,Delta(6) desaturase,Delta(6) fatty acid desaturase,Delta-6 desaturase,FADS2,Fatty acid desaturase 2
EIAAB14327 D5D,Delta(5) desaturase,Delta(5) fatty acid desaturase,Delta-5 desaturase,Fads1,Fatty acid desaturase 1,Mouse,Mus musculus
20-272-191926 SCD - Mouse monoclonal [CD.E10] to SCD; EC 1.14.19.1; Stearoyl-CoA desaturase; Fatty acid desaturase; Delta(9)-desaturase Monoclonal 0.1 mg
FADS21-A Anti-Mouse Fatty acid desaturase 2 (FADS2 delta-6 desaturase) IgG aff pure 100 ug
CSB-EL020802PI Pig stearoyl-CoA desaturase (delta-9-desaturase) (SCD) ELISA kit, Species Pig, Sample Type serum, plasma 96T
FADS21-P Mouse Fatty acid desaturase 2 (FADS2 delta-6 desaturase) Control blocking peptide 100 ug
E1386202 Sheep Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) ELISA Kit 1
GWB-C7B899 Anti- SCD (stearoyl-CoA desaturase (delta-9-desaturase)) Antibody
E13812313 Stearoyl-CoA Desaturase (Delta-9-Desaturase) (SCD) ELISA Kit 1
SCD SCD Gene stearoyl-CoA desaturase (delta-9-desaturase)
E3404h Human Sterol C5 Desaturase Like Protein ELISA Kit 96T
EIAAB13217 ANG1,Another new gene 1 protein,C-14 sterol reductase,Delta(14)-sterol reductase,Delta-14-SR,Homo sapiens,Human,Putative sterol reductase SR-1,Sterol C14-reductase,TM7SF2,Transmembrane 7 superfamily m
EIAAB12333 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase,Cholestenol Delta-isomerase,D8-D7 sterol isomerase,Delta(8)-Delta(7) sterol isomerase,Ebp,Emopamil-binding protein,Rat,Rattus norvegicus,Rsi,Sterol 8-
CSB-EL020802SH Sheep stearoyl-CoA desaturase (delta-9-desaturase) (SCD) ELISA kit, Species Sheep, Sample Type serum, plasma 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur