Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Delta-hemolysin (Delta-lysin) (Delta-toxin)

 HLD_STAAU               Reviewed;          26 AA.
P0C1V1; P01506; P0A0M3;
05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
18-MAR-2008, sequence version 2.
22-NOV-2017, entry version 54.
RecName: Full=Delta-hemolysin;
Short=Delta-lysin;
AltName: Full=Delta-toxin;
Name=hld;
Staphylococcus aureus.
Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
Staphylococcus.
NCBI_TaxID=1280;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Isolate GAL;
PubMed=7565609; DOI=10.1007/BF02191645;
Novick R.P., Projan S.J., Kornblum J., Ross H.F., Ji G.,
Kreiswirth B., Vandenesch F., Moghazeh S.;
"The agr P2 operon: an autocatalytic sensory transduction system in
Staphylococcus aureus.";
Mol. Gen. Genet. 248:446-458(1995).
[2]
PROTEIN SEQUENCE, AND FORMYLATION AT MET-1.
STRAIN=186X;
PubMed=7398877; DOI=10.1016/0014-5793(80)81170-7;
Fitton J.E., Dell A., Shaw W.V.;
"The amino acid sequence of the delta haemolysin of Staphylococcus
aureus.";
FEBS Lett. 115:209-212(1980).
[3]
PROTEIN SEQUENCE.
STRAIN=Canine variant;
Fitton J.E., Hunt D.F., Marasco J., Shabanowitz J., Winston S.,
Dell A.;
"The amino acid sequence of delta haemolysin purified from a canine
isolate of S. aureus.";
FEBS Lett. 169:25-29(1984).
[4]
3D-STRUCTURE MODELING.
PubMed=2281085; DOI=10.1002/prot.340080304;
Raghunathan G., Seetharamulu P., Brooks B.R., Guy H.R.;
"Models of delta-hemolysin membrane channels and crystal structures.";
Proteins 8:213-225(1990).
-!- FUNCTION: Lyses erythrocytes and many other mammalian cells.
-!- SUBCELLULAR LOCATION: Secreted. Host cell membrane. Note=In
infected cells, it is found in the membrane.
-!- SIMILARITY: Belongs to the delta-lysin family. {ECO:0000305}.
-!- SEQUENCE CAUTION:
Sequence=CAA36780.1; Type=Erroneous initiation; Evidence={ECO:0000305};
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; X52543; CAA36780.1; ALT_INIT; Genomic_DNA.
PIR; A01767; LESAD.
RefSeq; WP_000046022.1; NZ_MAQG01000017.1.
PDB; 1DHL; Model; -; A/B=1-26.
PDB; 1DTC; NMR; -; A=1-26.
PDB; 2DHL; Model; -; A/B=1-26.
PDB; 2DTB; NMR; -; A=1-26.
PDB; 2KAM; NMR; -; A=1-26.
PDB; 3DHL; Model; -; A/B=1-26.
PDBsum; 1DHL; -.
PDBsum; 1DTC; -.
PDBsum; 2DHL; -.
PDBsum; 2DTB; -.
PDBsum; 2KAM; -.
PDBsum; 3DHL; -.
ProteinModelPortal; P0C1V1; -.
SMR; P0C1V1; -.
DrugBank; DB04464; N-Formylmethionine.
TCDB; 1.C.122.1.1; the pore-forming delta-hemolysin (hld) family.
EvolutionaryTrace; P0C1V1; -.
PRO; PR:P0C1V1; -.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
GO; GO:0019836; P:hemolysis by symbiont of host erythrocytes; IEA:InterPro.
InterPro; IPR008034; Delta_lysin.
Pfam; PF05372; Delta_lysin; 1.
1: Evidence at protein level;
3D-structure; Cytolysis; Direct protein sequencing; Formylation;
Hemolysis; Host cell membrane; Host membrane; Membrane; Secreted;
Toxin; Transmembrane.
PEPTIDE 1 26 Delta-hemolysin.
/FTId=PRO_0000035648.
MOD_RES 1 1 N-formylmethionine.
{ECO:0000269|PubMed:7398877}.
VARIANT 3 3 Q -> A (in strain: canine).
VARIANT 10 12 GDL -> VEF (in strain: canine).
VARIANT 15 15 W -> L (in strain: canine).
VARIANT 17 18 ID -> AE (in strain: canine).
VARIANT 21 21 N -> E (in strain: canine).
VARIANT 24 24 T -> I (in strain: canine).
HELIX 2 22 {ECO:0000244|PDB:1DTC}.
SEQUENCE 26 AA; 2979 MW; 854433C5EFE4DFD2 CRC64;
MAQDIISTIG DLVKWIIDTV NKFTKK


Related products :

Catalog number Product name Quantity
EIAAB40068 Homo sapiens,Human,Signal sequence receptor subunit delta,SSR4,SSR-delta,Translocon-associated protein subunit delta,TRAPD,TRAP-delta
EIAAB31450 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4,Homo sapiens,hPLCD4,Human,Phosphoinositide phospholipase C-delta-4,Phospholipase C-delta-4,PLCD4,PLC-delta-4
EIAAB40069 Mouse,Mus musculus,Signal sequence receptor subunit delta,Ssr4,SSR-delta,Translocon-associated protein subunit delta,TRAP-delta
EIAAB40070 Bos taurus,Bovine,Signal sequence receptor subunit delta,SSR4,SSR-delta,Translocon-associated protein subunit delta,TRAP-delta
EIAAB31444 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3,Homo sapiens,Human,KIAA1964,Phosphoinositide phospholipase C-delta-3,Phospholipase C-delta-3,PLCD3,PLC-delta-3
EIAAB40071 Rat,Rattus norvegicus,Signal sequence receptor subunit delta,Ssr4,SSR-delta,Translocon-associated protein subunit delta,TRAP-delta
EIAAB31447 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4,Mouse,Mus musculus,Phosphoinositide phospholipase C-delta-4,Phospholipase C-delta-4,Plcd,Plcd4,PLC-delta-4
EIAAB31442 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1,Mouse,Mus musculus,Phosphoinositide phospholipase C-delta-1,Phospholipase C-delta-1,Plcd,Plcd1,PLC-delta-1
EIAAB31445 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3,Kiaa1964,Mouse,Mus musculus,Phosphoinositide phospholipase C-delta-3,Phospholipase C-delta-3,Plcd3,PLC-delta-3
15-288-22845 Translocon-associated protein subunit delta - TRAP-delta; Signal sequence receptor subunit delta; SSR-delta Polyclonal 0.1 mg
EIAAB31448 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4,Phosphoinositide phospholipase C-delta-4,Phospholipase C-delta-4,Plcd4,PLC-delta-4,Rat,Rattus norvegicus
15-288-22845 Translocon-associated protein subunit delta - TRAP-delta; Signal sequence receptor subunit delta; SSR-delta Polyclonal 0.05 mg
EIAAB12331 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase,Cholestenol Delta-isomerase,D8-D7 sterol isomerase,Delta(8)-Delta(7) sterol isomerase,EBP,Emopamil-binding protein,Homo sapiens,Human
EIAAB31449 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4,Phosphoinositide phospholipase C-delta-4,Phospholipase C-delta-4,Pig,PLCD4,PLC-delta-4,Sus scrofa
EIAAB12332 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase,Cholestenol Delta-isomerase,D8-D7 sterol isomerase,Delta(8)-Delta(7) sterol isomerase,Ebp,Emopamil-binding protein,Mouse,Msi,Mus musculus
EIAAB31446 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-4,Bos taurus,Bovine,Phosphoinositide phospholipase C-delta-4,Phospholipase C-delta-2,Phospholipase C-delta-4,PLC-85,PLCD2,PLCD4,PLC-delt
EIAAB37638 Amiloride-sensitive sodium channel subunit delta,Delta-ENaC,Delta-NaCH,DNACH,ENaCD,Epithelial Na(+) channel subunit delta,Homo sapiens,Human,Nonvoltage-gated sodium channel 1 subunit delta,SCNED,SCNN1
EIAAB31441 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1,Homo sapiens,Human,Phosphoinositide phospholipase C-delta-1,Phospholipase C-delta-1,Phospholipase C-III,PLCD1,PLC-delta-1,PLC-III
EIAAB31440 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1,Phosphoinositide phospholipase C-delta-1,Phospholipase C-delta-1,Phospholipase C-III,Plcd1,PLC-delta-1,PLC-III,Rat,Rattus norvegicus
EIAAB31443 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1,Bos taurus,Bovine,Phosphoinositide phospholipase C-delta-1,Phospholipase C-delta-1,Phospholipase C-III,PLCD1,PLC-delta-1,PLC-III
EIAAB12333 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase,Cholestenol Delta-isomerase,D8-D7 sterol isomerase,Delta(8)-Delta(7) sterol isomerase,Ebp,Emopamil-binding protein,Rat,Rattus norvegicus,Rsi,Sterol 8-
EIAAB41750 A45,Cct4,Cctd,CCT-delta,Mouse,Mus musculus,T-complex protein 1 subunit delta,TCP-1-delta
EIAAB11418 Delta3,Delta-like protein 3,Dll3,Drosophila Delta homolog 3,M-Delta-3,Mouse,Mus musculus
EIAAB08601 Archain,Arcn1,Coatomer subunit delta,Copd,Delta-coat protein,Delta-COP,Mouse,Mus musculus
EIAAB11413 Delta1,Delta-like protein 1,DLL1,Drosophila Delta homolog 1,H-Delta-1,Homo sapiens,Human,UNQ146_PRO172


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur