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Dermaseptin-J9 (DRS-J9)

 DMS9_PHAJA              Reviewed;          29 AA.
P86641;
08-FEB-2011, integrated into UniProtKB/Swiss-Prot.
08-FEB-2011, sequence version 1.
10-MAY-2017, entry version 7.
RecName: Full=Dermaseptin-J9 {ECO:0000303|PubMed:20932854};
Short=DRS-J9 {ECO:0000303|PubMed:20932854};
Phasmahyla jandaia (Jandaia leaf frog).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae;
Phyllomedusinae; Phasmahyla.
NCBI_TaxID=762504;
[1] {ECO:0000305}
PROTEIN SEQUENCE, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND MASS
SPECTROMETRY.
TISSUE=Skin secretion {ECO:0000269|PubMed:20932854};
PubMed=20932854; DOI=10.1016/j.toxicon.2010.09.010;
Rates B., Silva L.P., Ireno I.C., Leite F.S., Borges M.H.,
Bloch C. Jr., De Lima M.E., Pimenta A.M.;
"Peptidomic dissection of the skin secretion of Phasmahyla jandaia
(Bokermann and Sazima, 1978) (Anura, Hylidae, Phyllomedusinae).";
Toxicon 57:35-52(2011).
-!- FUNCTION: Has antimicrobial activity.
{ECO:0000250|UniProtKB:P84921}.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:20932854}.
-!- TISSUE SPECIFICITY: Expressed by the skin glands.
{ECO:0000269|PubMed:20932854}.
-!- MASS SPECTROMETRY: Mass=2983.5; Method=MALDI; Range=1-29;
Evidence={ECO:0000269|PubMed:20932854};
-!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
Dermaseptin subfamily. {ECO:0000255}.
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SMR; P86641; -.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
InterPro; IPR022731; Dermaseptin.
InterPro; IPR020194; Dermaseptin_anura.
Pfam; PF12121; DD_K; 1.
ProDom; PD049440; Dermaseptin_tree-frog; 1.
1: Evidence at protein level;
Amphibian defense peptide; Antibiotic; Antimicrobial;
Direct protein sequencing; Secreted.
PEPTIDE 1 29 Dermaseptin-J9.
{ECO:0000269|PubMed:20932854}.
/FTId=PRO_0000404618.
UNSURE 2 2 L or I. {ECO:0000269|PubMed:20932854}.
UNSURE 4 4 K or Q. {ECO:0000269|PubMed:20932854}.
UNSURE 6 6 L or I. {ECO:0000269|PubMed:20932854}.
UNSURE 7 7 L or I. {ECO:0000269|PubMed:20932854}.
UNSURE 8 8 K or Q. {ECO:0000269|PubMed:20932854}.
UNSURE 12 12 K or Q. {ECO:0000269|PubMed:20932854}.
UNSURE 16 16 K or Q. {ECO:0000269|PubMed:20932854}.
UNSURE 19 19 L or I. {ECO:0000269|PubMed:20932854}.
UNSURE 28 28 Q or K. {ECO:0000269|PubMed:20932854}.
SEQUENCE 29 AA; 2985 MW; D504901BAFB9C37C CRC64;
GLWKSLLKNV GKAAGKAALN AVTDMVNQS


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