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Dermorphin

 DEM_PHYAZ               Reviewed;           7 AA.
P85887;
02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
02-SEP-2008, sequence version 1.
10-MAY-2017, entry version 9.
RecName: Full=Dermorphin {ECO:0000303|PubMed:17696382};
Phyllomedusa azurea (Orange-legged monkey frog) (Phyllomedusa
hypochondrialis azurea).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Hylidae;
Phyllomedusinae; Phyllomedusa.
NCBI_TaxID=394475;
[1] {ECO:0000305}
PROTEIN SEQUENCE, MASS SPECTROMETRY, HYDROXYLATION AT PRO-6, AND
AMIDATION AT SER-7.
TISSUE=Skin secretion {ECO:0000269|PubMed:17696382};
PubMed=17696382; DOI=10.1021/pr0702666;
Thompson A.H., Bjourson A.J., Orr D.F., Shaw C., McClean S.;
"Amphibian skin secretomics: application of parallel quadrupole time-
of-flight mass spectrometry and peptide precursor cDNA cloning to
rapidly characterize the skin secretory peptidome of Phyllomedusa
hypochondrialis azurea: discovery of a novel peptide family, the
hyposins.";
J. Proteome Res. 6:3604-3613(2007).
-!- FUNCTION: Dermorphin has a very potent opiate-like activity. It
has high affinity and selectivity for mu-type opioid receptors (By
similarity). {ECO:0000250|UniProtKB:P05422}.
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17696382}.
-!- TISSUE SPECIFICITY: Expressed by the venom gland.
{ECO:0000269|PubMed:17696382}.
-!- MASS SPECTROMETRY: Mass=818.38; Method=MALDI; Range=1-7;
Evidence={ECO:0000269|PubMed:17696382};
-!- SIMILARITY: Belongs to the frog skin active peptide (FSAP) family.
Dermorphin subfamily. {ECO:0000255}.
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HOVERGEN; HBG051336; -.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0001515; F:opioid peptide activity; IEA:UniProtKB-KW.
GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
1: Evidence at protein level;
Amidation; Amphibian defense peptide; Direct protein sequencing;
Endorphin; Hydroxylation; Opioid peptide; Secreted.
PEPTIDE 1 7 Dermorphin.
{ECO:0000269|PubMed:17696382}.
/FTId=PRO_0000345631.
MOD_RES 6 6 Hydroxyproline.
{ECO:0000269|PubMed:17696382}.
MOD_RES 7 7 Serine amide.
{ECO:0000269|PubMed:17696382}.
SEQUENCE 7 AA; 804 MW; 75A77B5879CDCB30 CRC64;
YAFGYPS


Related products :

Catalog number Product name Quantity
D-0305 (D-Arg2,Sar4)-Dermorphin (1-4) Dermorphin Analog (1-4), TAPS 98 percent C27H37N7O6 CAS: 90549-86-3 5mg
orb71542 Dermorphin peptide This is Dermorphin peptide. For research use only. 1 mg
orb70217 [Phe4]-Dermorphin (1-4) peptide This is [Phe4]-Dermorphin (1-4) peptide. For research use only. 1 mg
orb70119 [D-Arg2]-Dermorphin (1-4) peptide This is [D-Arg2]-Dermorphin (1-4) peptide. For research use only. 1 mg
orb70600 Dermorphin Analog peptide This is Dermorphin Analog peptide. For research use only. 1 mg
orb70121 [D-Arg2,Sar4]-Dermorphin (1-4) peptide This is [D-Arg2,Sar4]-Dermorphin (1-4) peptide. For research use only. 1 mg
orb70120 [D-Arg2,Lys4]-Dermorphin (1-4) peptide This is [D-Arg2,Lys4]-Dermorphin (1-4) peptide. For research use only. 1 mg
020-01 Dermorphin _ 5mg 5 mg
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SP3268a Dermorphin 3
06-271-83188 Dermorphin - 5 mg
RP10427 Dermorphin 5mg
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AR05040PU-N Dermorphin 1 mg
SP-52238-1 Dermorphin 1 mg
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AR05040PU-N Dermorphin 1 mg
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