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Dipeptidyl peptidase 8 (Fragment)

 H0YK36_HUMAN            Unreviewed;       361 AA.
H0YK36;
22-FEB-2012, integrated into UniProtKB/TrEMBL.
18-APR-2012, sequence version 2.
28-MAR-2018, entry version 35.
SubName: Full=Dipeptidyl peptidase 8 {ECO:0000313|Ensembl:ENSP00000452643};
Flags: Fragment;
Name=DPP8 {ECO:0000313|Ensembl:ENSP00000452643};
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000452643, ECO:0000313|Proteomes:UP000005640};
[1] {ECO:0000313|Ensembl:ENSP00000452643, ECO:0000313|Proteomes:UP000005640}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=16572171; DOI=10.1038/nature04601;
Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
Nusbaum C.;
"Analysis of the DNA sequence and duplication history of human
chromosome 15.";
Nature 440:671-675(2006).
[2] {ECO:0000313|Ensembl:ENSP00000452643}
IDENTIFICATION.
Ensembl;
Submitted (JAN-2012) to UniProtKB.
-!- SIMILARITY: Belongs to the peptidase S9B family.
{ECO:0000256|SAAS:SAAS01028250}.
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EMBL; AC011846; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AC105129; -; NOT_ANNOTATED_CDS; Genomic_DNA.
ProteinModelPortal; H0YK36; -.
EPD; H0YK36; -.
MaxQB; H0YK36; -.
PeptideAtlas; H0YK36; -.
PRIDE; H0YK36; -.
Ensembl; ENST00000558559; ENSP00000452643; ENSG00000074603.
UCSC; uc059kjl.1; human.
EuPathDB; HostDB:ENSG00000074603.18; -.
HGNC; HGNC:16490; DPP8.
OpenTargets; ENSG00000074603; -.
eggNOG; KOG2281; Eukaryota.
eggNOG; COG1506; LUCA.
GeneTree; ENSGT00760000119233; -.
ChiTaRS; DPP8; human.
Proteomes; UP000005640; Chromosome 15.
Bgee; ENSG00000074603; -.
ExpressionAtlas; H0YK36; baseline and differential.
GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
Gene3D; 2.140.10.30; -; 2.
Gene3D; 3.40.50.1820; -; 1.
InterPro; IPR029058; AB_hydrolase.
InterPro; IPR001375; Peptidase_S9.
InterPro; IPR002469; Peptidase_S9B_N.
InterPro; IPR038554; Peptidase_S9B_N_sf.
Pfam; PF00930; DPPIV_N; 2.
Pfam; PF00326; Peptidase_S9; 1.
SUPFAM; SSF53474; SSF53474; 1.
1: Evidence at protein level;
Complete proteome {ECO:0000313|Proteomes:UP000005640};
Proteomics identification {ECO:0000213|EPD:H0YK36,
ECO:0000213|MaxQB:H0YK36, ECO:0000213|PeptideAtlas:H0YK36};
Reference proteome {ECO:0000313|Proteomes:UP000005640}.
DOMAIN 3 90 DPPIV_N. {ECO:0000259|Pfam:PF00930}.
DOMAIN 98 164 DPPIV_N. {ECO:0000259|Pfam:PF00930}.
DOMAIN 256 359 Peptidase_S9. {ECO:0000259|Pfam:PF00326}.
NON_TER 1 1 {ECO:0000313|Ensembl:ENSP00000452643}.
NON_TER 361 361 {ECO:0000313|Ensembl:ENSP00000452643}.
SEQUENCE 361 AA; 41197 MW; A85E30582DBB4FD4 CRC64;
XEEDARSAGV ATFVLQEEFD RYSGYWWCPK AETTPSGGKI LRILYEENDE SEVEIIHVTS
PMLETRRADS FRYPKTGTAN PKVTFKMSEI MIDAEGRIQV DEVRRLVYFE GTKDSPLEHH
LYVVSYVNPG EVTRLTDRGY SHSCCISQHC DFFISKYSNQ KNPHCVSLYK LSSPEDDPTC
KTKEFWATIL DSAGPLPDYT PPEIFSFEST TGFTLYGMLY KPHDLQPGKK YPTVLFIYGG
PQVQLVNNRF KGVKYFRLNT LASLGYVVVV IDNRGSCHRG LKFEGAFKYK MGQIEIDDQV
EGLQYLASRY DFIDLDRVGI HGWSYGGYLS LMALMQRSDI FRVAIAGAPV TLWIFYDTGY
T


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