Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (mDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)

 DAPP1_MOUSE             Reviewed;         280 AA.
Q9QXT1; Q9R178;
05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
07-NOV-2018, entry version 131.
RecName: Full=Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;
Short=mDAPP1;
AltName: Full=B lymphocyte adapter protein Bam32;
AltName: Full=B-cell adapter molecule of 32 kDa;
Name=Dapp1; Synonyms=Bam32;
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
Muroidea; Muridae; Murinae; Mus; Mus.
NCBI_TaxID=10090;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=10432293; DOI=10.1042/bj3420007;
Dowler S., Currie R.A., Downes C.P., Alessi D.R.;
"DAPP1: a dual adaptor for phosphotyrosine and 3-phosphoinositides.";
Biochem. J. 342:7-12(1999).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=BALB/cJ;
PubMed=10770799; DOI=10.1084/jem.191.8.1319;
Marshall A.J., Niiro H., Lerner C.G., Yun T.J., Thomas S.,
Disteche C.M., Clark E.A.;
"A novel B lymphocyte-associated adaptor protein, Bam32, regulates
antigen receptor signaling downstream of phosphatidylinositol 3-
kinase.";
J. Exp. Med. 191:1319-1332(2000).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[4]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-139 AND SER-141, AND
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
TISSUE=Mast cell;
PubMed=17947660; DOI=10.4049/jimmunol.179.9.5864;
Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y.,
Kawakami T., Salomon A.R.;
"Quantitative time-resolved phosphoproteomic analysis of mast cell
signaling.";
J. Immunol. 179:5864-5876(2007).
[5]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-139, AND IDENTIFICATION
BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=19144319; DOI=10.1016/j.immuni.2008.11.006;
Trost M., English L., Lemieux S., Courcelles M., Desjardins M.,
Thibault P.;
"The phagosomal proteome in interferon-gamma-activated macrophages.";
Immunity 30:143-154(2009).
-!- FUNCTION: May act as a B-cell-associated adapter that regulates B-
cell antigen receptor (BCR)-signaling downstream of PI3K.
-!- SUBUNIT: Interacts with PtdIns(3,4,5)P3 and PLCG2. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Membrane
{ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Note=Membrane-associated after cell stimulation leading to its
translocation. {ECO:0000250}.
-!- INDUCTION: Upon B-cell activation. {ECO:0000250}.
-!- PTM: Phosphorylated on tyrosine residues. {ECO:0000250}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AF163255; AAD49698.1; -; mRNA.
EMBL; AF186023; AAF14579.1; -; mRNA.
EMBL; BC014759; AAH14759.1; -; mRNA.
CCDS; CCDS17864.1; -.
RefSeq; NP_036062.1; NM_011932.3.
UniGene; Mm.254835; -.
UniGene; Mm.470427; -.
ProteinModelPortal; Q9QXT1; -.
SMR; Q9QXT1; -.
STRING; 10090.ENSMUSP00000029806; -.
iPTMnet; Q9QXT1; -.
PhosphoSitePlus; Q9QXT1; -.
EPD; Q9QXT1; -.
MaxQB; Q9QXT1; -.
PaxDb; Q9QXT1; -.
PRIDE; Q9QXT1; -.
Ensembl; ENSMUST00000029806; ENSMUSP00000029806; ENSMUSG00000028159.
GeneID; 26377; -.
KEGG; mmu:26377; -.
UCSC; uc008rmt.1; mouse.
CTD; 27071; -.
MGI; MGI:1347063; Dapp1.
eggNOG; ENOG410IF6C; Eukaryota.
eggNOG; ENOG410XSW5; LUCA.
GeneTree; ENSGT00910000144274; -.
HOGENOM; HOG000112147; -.
HOVERGEN; HBG051297; -.
InParanoid; Q9QXT1; -.
KO; K12229; -.
OMA; KVNCFCL; -.
OrthoDB; EOG091G0HCX; -.
PhylomeDB; Q9QXT1; -.
TreeFam; TF105418; -.
Reactome; R-MMU-983695; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.
PRO; PR:Q9QXT1; -.
Proteomes; UP000000589; Chromosome 3.
Bgee; ENSMUSG00000028159; Expressed in 167 organ(s), highest expression level in blood.
ExpressionAtlas; Q9QXT1; baseline and differential.
Genevisible; Q9QXT1; MM.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0016020; C:membrane; IBA:GO_Central.
GO; GO:0005886; C:plasma membrane; ISO:MGI.
GO; GO:0030165; F:PDZ domain binding; IBA:GO_Central.
GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; ISO:MGI.
GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; ISO:MGI.
CDD; cd10355; SH2_DAPP1_BAM32_like; 1.
Gene3D; 2.30.29.30; -; 1.
Gene3D; 3.30.505.10; -; 1.
InterPro; IPR035843; DAPP1_SH2.
InterPro; IPR011993; PH-like_dom_sf.
InterPro; IPR001849; PH_domain.
InterPro; IPR000980; SH2.
InterPro; IPR036860; SH2_dom_sf.
Pfam; PF00169; PH; 1.
Pfam; PF00017; SH2; 1.
PRINTS; PR00401; SH2DOMAIN.
SMART; SM00233; PH; 1.
SMART; SM00252; SH2; 1.
SUPFAM; SSF55550; SSF55550; 1.
PROSITE; PS50003; PH_DOMAIN; 1.
PROSITE; PS50001; SH2; 1.
1: Evidence at protein level;
Complete proteome; Cytoplasm; Membrane; Phosphoprotein;
Reference proteome; SH2 domain.
CHAIN 1 280 Dual adapter for phosphotyrosine and 3-
phosphotyrosine and 3-phosphoinositide.
/FTId=PRO_0000079786.
DOMAIN 35 129 SH2. {ECO:0000255|PROSITE-
ProRule:PRU00191}.
DOMAIN 164 259 PH. {ECO:0000255|PROSITE-
ProRule:PRU00145}.
MOD_RES 139 139 Phosphotyrosine.
{ECO:0000244|PubMed:17947660,
ECO:0000244|PubMed:19144319}.
MOD_RES 141 141 Phosphoserine.
{ECO:0000244|PubMed:17947660}.
CONFLICT 90 90 Y -> C (in Ref. 1; AAD49698).
{ECO:0000305}.
SEQUENCE 280 AA; 32167 MW; D15CF545A710F7F0 CRC64;
MGRAELLGGN MSTQDPSELW GRADGGTDLL QDLGWYHGNL TRHAAEALLL SNGRDGSYLL
RDSNEQTGLY SLSVRAKDSV KHFHVEYTGY SFKFGFNEYS SLKDFVKHFA NQPLIGSETG
TLMVLKHPYP REVEEPCIYE SVRVHTAMQT GRTENDLVPT APSLGTKEGY LTKQGGLVKT
WKTRWFTLQR NELKYFKDQM SPEPIRILDL TECSAVQFDY SQERVNCFCL VFPFRTFYLC
AKTGVEADEW IKILRWKLSK IRKQLDQGED TVRSRSFIFK


Related products :

Catalog number Product name Quantity
EIAAB10418 B lymphocyte adapter protein Bam32,Bam32,B-cell adapter molecule of 32 kDa,Dapp1,Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide,mDAPP1,Mouse,Mus musculus
EIAAB10419 B lymphocyte adapter protein Bam32,BAM32,B-cell adapter molecule of 32 kDa,DAPP1,Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide,hDAPP1,Homo sapiens,HSPC066,Human
15-288-21544 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide - hDAPP1; B cell adapter molecule of 32 kDa; B lymphocyte adapter protein Bam32 Polyclonal 0.1 mg
15-288-21544 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide - hDAPP1; B cell adapter molecule of 32 kDa; B lymphocyte adapter protein Bam32 Polyclonal 0.05 mg
CSB-EL006503HU Human Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(DAPP1) ELISA kit 96T
CSB-EL006503MO Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(DAPP1) ELISA kit 96T
FP-0022 Fusion proteins: Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide , DAPP1 10ug
FP-0022 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide ; SH2-Domain: DAPP1 10ug
DAPP1_MOUSE Mouse ELISA Kit FOR Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide 96T
CSB-EL006503MO Mouse Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(DAPP1) ELISA kit SpeciesMouse 96T
CSB-EL006503HU Human Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide(DAPP1) ELISA kit SpeciesHuman 96T
DAPP1_MOUSE ELISA Kit FOR Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide; organism: Mouse; gene name: Dapp1 96T
FP-0022 Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide 10ug
U1600m CLIA Bash,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,B-cell linker protein,Blnk,Cytoplasmic adapter protein,Ly57,Lymphocyte antigen 57,Mou 96T
E1600m ELISA kit Bash,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,B-cell linker protein,Blnk,Cytoplasmic adapter protein,Ly57,Lymphocyte antigen 96T
E1600m ELISA Bash,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,B-cell linker protein,Blnk,Cytoplasmic adapter protein,Ly57,Lymphocyte antigen 57,Mo 96T
EIAAB38197 Homo sapiens,Human,LNK,Lymphocyte adapter protein,Lymphocyte-specific adapter protein Lnk,SH2B adapter protein 3,SH2B3,Signal transduction protein Lnk
EIAAB38198 Lnk,Lymphocyte adapter protein,Lymphocyte-specific adapter protein Lnk,Rat,Rattus norvegicus,SH2B adapter protein 3,Sh2b3,Signal transduction protein Lnk
EIAAB38196 Lnk,Lymphocyte adapter protein,Lymphocyte-specific adapter protein Lnk,Mouse,Mus musculus,SH2B adapter protein 3,Sh2b3,Signal transduction protein Lnk
18-661-15184 TRIF-related adapter molecule - TICAM2 protein; TIRAP3a; TIRAP3a short form; TIR-containing adapter molecule-2; TIR domain-containing adapter protein; Putative NFkB activating protein Polyclonal 0.1 mg
18-661-15165 TRIF-related adapter molecule - TICAM2 protein; TIRAP3a; TIRAP3a short form; TIR-containing adapter molecule-2; TIR domain-containing adapter protein; Putative NFkB activating protein Polyclonal 0.1 mg
FP-0022 Dual adapter for phosphotyrosine and 3_phosphotyrosine and 3_phosphoinositide 10 ug
EIAAB41674 Mouse,Mus musculus,Ticam1,TICAM-1,TIR domain-containing adapter molecule 1,TIR domain-containing adapter protein inducing IFN-beta,Toll-interleukin-1 receptor domain-containing adapter protein inducin
E1600h ELISA kit BASH,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,B-cell linker protein,BLNK,Cytoplasmic adapter protein,Homo sapiens,Human,SLP65 96T
U1600h CLIA BASH,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,B-cell linker protein,BLNK,Cytoplasmic adapter protein,Homo sapiens,Human,SLP65,SLP-6 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur