Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Dual specificity protein phosphatase (EC 3 1 3 16) (EC 3 1 3 48)

 J9P4Q2_CANLF            Unreviewed;       369 AA.
J9P4Q2;
31-OCT-2012, integrated into UniProtKB/TrEMBL.
31-OCT-2012, sequence version 1.
20-JUN-2018, entry version 38.
RecName: Full=Dual specificity protein phosphatase {ECO:0000256|PIRNR:PIRNR000939};
EC=3.1.3.16 {ECO:0000256|PIRNR:PIRNR000939};
EC=3.1.3.48 {ECO:0000256|PIRNR:PIRNR000939};
Name=DUSP1 {ECO:0000313|Ensembl:ENSCAFP00000040531,
ECO:0000313|VGNC:VGNC:51892};
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615 {ECO:0000313|Ensembl:ENSCAFP00000040531, ECO:0000313|Proteomes:UP000002254};
[1] {ECO:0000313|Ensembl:ENSCAFP00000040531, ECO:0000313|Proteomes:UP000002254}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000040531,
ECO:0000313|Proteomes:UP000002254};
PubMed=16341006; DOI=10.1038/nature04338;
Broad Sequencing Platform;
Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C.,
Mauceli E., Xie X., Breen M., Wayne R.K., Ostrander E.A.,
Ponting C.P., Galibert F., Smith D.R., deJong P.J., Kirkness E.F.,
Alvarez P., Biagi T., Brockman W., Butler J., Chin C.-W., Cook A.,
Cuff J., Daly M.J., DeCaprio D., Gnerre S., Grabherr M., Kellis M.,
Kleber M., Bardeleben C., Goodstadt L., Heger A., Hitte C., Kim L.,
Koepfli K.-P., Parker H.G., Pollinger J.P., Searle S.M.J.,
Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L.,
Bachantsang P., Barry A., Bayul T., Benamara M., Berlin A.,
Bessette D., Blitshteyn B., Bloom T., Blye J., Boguslavskiy L.,
Bonnet C., Boukhgalter B., Brown A., Cahill P., Calixte N.,
Camarata J., Cheshatsang Y., Chu J., Citroen M., Collymore A.,
Cooke P., Dawoe T., Daza R., Decktor K., DeGray S., Dhargay N.,
Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L., Duffey N.,
Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K.,
Foley C., Franke A., Friedrich D., Gage D., Garber M., Gearin G.,
Giannoukos G., Goode T., Goyette A., Graham J., Grandbois E.,
Gyaltsen K., Hafez N., Hagopian D., Hagos B., Hall J., Healy C.,
Hegarty R., Honan T., Horn A., Houde N., Hughes L., Hunnicutt L.,
Husby M., Jester B., Jones C., Kamat A., Kanga B., Kells C.,
Khazanovich D., Kieu A.C., Kisner P., Kumar M., Lance K., Landers T.,
Lara M., Lee W., Leger J.-P., Lennon N., Leuper L., LeVine S., Liu J.,
Liu X., Lokyitsang Y., Lokyitsang T., Lui A., Macdonald J., Major J.,
Marabella R., Maru K., Matthews C., McDonough S., Mehta T.,
Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T., Miller K.,
Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A., Naylor J.,
Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K.,
Osman S., Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F.,
Priest M., Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C.,
Rege F., Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S.,
Sharpe T., Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J.,
Smith C., Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S.,
Stone C., Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S.,
Thoulutsang D., Thoulutsang Y., Topham K., Topping I., Tsamla T.,
Vassiliev H., Venkataraman V., Vo A., Wangchuk T., Wangdi T.,
Weiand M., Wilkinson J., Wilson A., Yadav S., Yang S., Yang X.,
Young G., Yu Q., Zainoun J., Zembek L., Zimmer A., Lander E.S.;
"Genome sequence, comparative analysis and haplotype structure of the
domestic dog.";
Nature 438:803-819(2005).
[2] {ECO:0000313|Ensembl:ENSCAFP00000040531}
IDENTIFICATION.
STRAIN=Boxer {ECO:0000313|Ensembl:ENSCAFP00000040531};
Ensembl;
Submitted (SEP-2012) to UniProtKB.
-!- CATALYTIC ACTIVITY: Protein tyrosine phosphate + H(2)O = protein
tyrosine + phosphate. {ECO:0000256|PIRNR:PIRNR000939}.
-!- CATALYTIC ACTIVITY: [a protein]-serine/threonine phosphate + H(2)O
= [a protein]-serine/threonine + phosphate.
{ECO:0000256|PIRNR:PIRNR000939}.
-!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family.
Non-receptor class dual specificity subfamily.
{ECO:0000256|PIRNR:PIRNR000939, ECO:0000256|SAAS:SAAS00724126}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AAEX03003007; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9615.ENSCAFP00000040531; -.
PaxDb; J9P4Q2; -.
Ensembl; ENSCAFT00000047739; ENSCAFP00000040531; ENSCAFG00000029826.
VGNC; VGNC:51892; DUSP1.
eggNOG; KOG1716; Eukaryota.
eggNOG; COG2453; LUCA.
GeneTree; ENSGT00760000118902; -.
InParanoid; J9P4Q2; -.
OMA; MVIMEVP; -.
OrthoDB; EOG091G0249; -.
TreeFam; TF105122; -.
Reactome; R-CFA-112409; RAF-independent MAPK1/3 activation.
Reactome; R-CFA-5675221; Negative regulation of MAPK pathway.
Proteomes; UP000002254; Chromosome 4.
Bgee; ENSCAFG00000029826; -.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0005634; C:nucleus; IEA:Ensembl.
GO; GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:Ensembl.
GO; GO:0051019; F:mitogen-activated protein kinase binding; IEA:Ensembl.
GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:Ensembl.
GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
GO; GO:0001706; P:endoderm formation; IBA:GO_Central.
GO; GO:0008285; P:negative regulation of cell proliferation; IEA:Ensembl.
GO; GO:0070262; P:peptidyl-serine dephosphorylation; IEA:Ensembl.
GO; GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:Ensembl.
GO; GO:0042981; P:regulation of apoptotic process; IBA:GO_Central.
CDD; cd00127; DSPc; 1.
Gene3D; 3.90.190.10; -; 1.
InterPro; IPR020417; Atypical_DUSP.
InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
InterPro; IPR024950; DUSP.
InterPro; IPR008343; MKP.
InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
InterPro; IPR016130; Tyr_Pase_AS.
InterPro; IPR003595; Tyr_Pase_cat.
InterPro; IPR000387; TYR_PHOSPHATASE_dom.
InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
PANTHER; PTHR10159; PTHR10159; 1.
Pfam; PF00782; DSPc; 1.
PIRSF; PIRSF000939; MAPK_Ptase; 1.
PRINTS; PR01908; ADSPHPHTASE.
PRINTS; PR01764; MAPKPHPHTASE.
SMART; SM00195; DSPc; 1.
SMART; SM00404; PTPc_motif; 1.
SUPFAM; SSF52799; SSF52799; 1.
PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000002254};
Hydrolase {ECO:0000256|PIRNR:PIRNR000939};
Protein phosphatase {ECO:0000256|PIRNR:PIRNR000939};
Reference proteome {ECO:0000313|Proteomes:UP000002254}.
DOMAIN 175 315 Tyrosine-protein phosphatase.
{ECO:0000259|PROSITE:PS50054}.
DOMAIN 240 294 TYR_PHOSPHATASE_2.
{ECO:0000259|PROSITE:PS50056}.
ACT_SITE 260 260 Phosphocysteine intermediate.
{ECO:0000256|PIRSR:PIRSR000939-1}.
SEQUENCE 369 AA; 39573 MW; 23FA04D0A99D96EE CRC64;
IVVDVGAVHA GVLRTLLRER AAQCLLLDCR FFLAANAGHS AGSGHVRFRT MVQRRDRGAT
GPEPVGPLAR RRGRLRAGAH PARVLLLKRT PPGGARAPRP APRAPRPAPA GPQPPRAAPP
GLPEEGYEAF SASCPELCSK QSTPMGLSLP LSTSVPDSTE SGCSSCSTPL YDQGGPVEIL
PFLYLGSAYH ASRKDMLDAL GITALINVSA NCPNHFEGHY QYKSIPVEDN HKADISSWFN
EAIDFIDSIK NAGGRVFVHC QAGISRSATI CLAYLMRTNR VKLDEAFEFV KQRRSIISPN
FSFMGQLLQF ESQVLAPHCS AEAGSPAMAV LDRSTSTTTV FNFPVSIPVH STNSALSYLQ
SPITTSPSC


Related products :

Catalog number Product name Quantity
EIAAB12065 Dual specificity phosphatase TS-DSP1,Dual specificity protein phosphatase 19,DUSP17,DUSP19,Homo sapiens,Human,LMWDSP3,LMW-DSP3,Low molecular weight dual specificity phosphatase 3,Protein phosphatase S
EIAAB12078 DSP-4,Dual specificity phosphatase SKRP3,Dual specificity protein phosphatase 26,DUSP24,DUSP26,Homo sapiens,Human,LDP4,LDP-4,Low-molecular-mass dual-specificity phosphatase 4,MAP kinase phosphatase 8,
18-461-10231 Dual specificity phosphatase 26 - Low-molecular-mass dual-specificity phosphatase 4; Dual-specificity phosphatase SKRP3; Mitogen-activated protein kinase phosphatase 8; NATA1 protein; CDNA FLJ31142 fi 0.05 ml
18-461-10232 Dual specificity phosphatase 26 - Low-molecular-mass dual-specificity phosphatase 4; Dual-specificity phosphatase SKRP3; Mitogen-activated protein kinase phosphatase 8; NATA1 protein; CDNA FLJ31142 fi 0.05 ml
EIAAB12052 Dual specificity phosphatase T-DSP4,Dual specificity phosphatase VH1,Dual specificity protein phosphatase 12,Dusp12,Mouse,Mus musculus
EIAAB12073 Dual specificity protein phosphatase 22,DUSP22,Homo sapiens,Human,JNK-stimulatory phosphatase-1,JSP1,JSP-1,LMWDSP2,LMW-DSP2,Low molecular weight dual specificity phosphatase 2,MAP kinase phosphatase x
EIAAB12041 CL100,Dual specificity protein phosphatase 1,Dual specificity protein phosphatase hVH1,DUSP1,Homo sapiens,Human,MAP kinase phosphatase 1,Mitogen-activated protein kinase phosphatase 1,MKP1,MKP-1,Prote
EIAAB12093 Dual specificity protein phosphatase 4,Dual specificity protein phosphatase hVH2,DUSP4,Homo sapiens,Human,MAP kinase phosphatase 2,Mitogen-activated protein kinase phosphatase 2,MKP2,MKP-2,VH2
EIAAB12075 Dual specificity protein phosphatase 23,DUSP23,Homo sapiens,Human,LDP3,LDP-3,Low molecular mass dual specificity phosphatase 3,VH1-like phosphatase Z,VHZ
EIAAB12087 Dual specificity protein phosphatase 3,Dual specificity protein phosphatase VHR,DUSP3,Homo sapiens,Human,Vaccinia H1-related phosphatase,VHR,VHR
EIAAB40510 Dual specificity phosphatase inhibitor MK-STYX,Dual specificity protein phosphatase 24,DUSP24,Homo sapiens,Human,Map kinase phosphatase-like protein MK-STYX,MKSTYX,Serine_threonine_tyrosine-interactin
EIAAB12101 Dual specificity protein phosphatase 6,Dual specificity protein phosphatase PYST1,DUSP6,Homo sapiens,Human,MAP kinase phosphatase 3,Mitogen-activated protein kinase phosphatase 3,MKP3,MKP-3,PYST1
EIAAB12071 Dual specificity protein phosphatase 21,DUSP21,Homo sapiens,Human,LMWDSP21,LMW-DSP21,Low molecular weight dual specificity phosphatase 21
EIAAB12063 Dual specificity protein phosphatase 18,DUSP18,Homo sapiens,Human,LMWDSP20,LMW-DSP20,Low molecular weight dual specificity phosphatase 20
EIAAB12053 Dual specificity phosphatase SKRP4,Dual specificity protein phosphatase 13,DUSP13,Homo sapiens,Human,Testis- and skeletal-muscle-specific DSP,TMDP
18-461-10238 Dual specificity protein phosphatase 23 - EC 3.1.3.48; EC 3.1.3.16; Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z Polyclonal 0.05 ml
15-288-21550 Dual specificity protein phosphatase 23 - EC 3.1.3.48; EC 3.1.3.16; Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z Polyclonal 0.1 mg
15-288-21550 Dual specificity protein phosphatase 23 - EC 3.1.3.48; EC 3.1.3.16; Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z Polyclonal 0.05 mg
EIAAB12054 Dual specificity protein phosphatase 13,Dual specificity tyrosine phosphatase TS-DSP6,Dusp13,Gm1203,Mouse,Mus musculus,Testis- and skeletal muscle-specific DSP,Tmdp
EIAAB12072 Dual specificity protein phosphatase 22,Dusp22,LMW-DSP2,Low molecular weight dual specificity phosphatase 2,Mouse,Mus musculus
EIAAB12051 Dual specificity protein phosphatase 12,Dual specificity tyrosine phosphatase YVH1,DUSP12,Homo sapiens,Human
EIAAB12074 Dual specificity protein phosphatase 23,Dusp23,Ldp3,LDP-3,Low molecular mass dual specificity phosphatase 3,Mouse,Mus musculus
E2144h ELISA Dual specificity protein phosphatase 2,Dual specificity protein phosphatase PAC-1,DUSP2,Homo sapiens,Human,PAC1 96T
U2144h CLIA kit Dual specificity protein phosphatase 2,Dual specificity protein phosphatase PAC-1,DUSP2,Homo sapiens,Human,PAC1 96T
U2144h CLIA Dual specificity protein phosphatase 2,Dual specificity protein phosphatase PAC-1,DUSP2,Homo sapiens,Human,PAC1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur