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EMD protein (Emerin)

 Q3SX08_BOVIN            Unreviewed;       261 AA.
Q3SX08;
11-OCT-2005, integrated into UniProtKB/TrEMBL.
11-OCT-2005, sequence version 1.
07-NOV-2018, entry version 99.
SubName: Full=EMD protein {ECO:0000313|EMBL:AAI04568.1};
SubName: Full=Emerin {ECO:0000313|Ensembl:ENSBTAP00000030177};
Name=EMD {ECO:0000313|EMBL:AAI04568.1,
ECO:0000313|Ensembl:ENSBTAP00000030177, ECO:0000313|VGNC:VGNC:28469};
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913 {ECO:0000313|EMBL:AAI04568.1};
[1] {ECO:0000313|EMBL:AAI04568.1}
NUCLEOTIDE SEQUENCE.
STRAIN=L1 Hereford {ECO:0000313|EMBL:AAI04568.1};
TISSUE=Uterus {ECO:0000313|EMBL:AAI04568.1};
Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y.,
Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C.,
Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J.,
Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J.,
Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D.,
Siddiqui A., Holt R., Jones S.J., Marra M.A.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSBTAP00000030177, ECO:0000313|Proteomes:UP000009136}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000030177,
ECO:0000313|Proteomes:UP000009136};
PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42;
Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C.,
Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S.,
Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.;
"A whole-genome assembly of the domestic cow, Bos taurus.";
Genome Biol. 10:R42.01-R42.10(2009).
[3] {ECO:0000313|Ensembl:ENSBTAP00000030177}
IDENTIFICATION.
STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000030177};
Ensembl;
Submitted (MAR-2016) to UniProtKB.
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EMBL; DAAA02070095; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC104567; AAI04568.1; -; mRNA.
UniGene; Bt.4016; -.
SMR; Q3SX08; -.
STRING; 9913.ENSBTAP00000030177; -.
PRIDE; Q3SX08; -.
Ensembl; ENSBTAT00000030192; ENSBTAP00000030177; ENSBTAG00000022314.
VGNC; VGNC:28469; EMD.
eggNOG; ENOG410IJ10; Eukaryota.
eggNOG; ENOG410ZEWX; LUCA.
GeneTree; ENSGT00390000002034; -.
HOGENOM; HOG000081509; -.
HOVERGEN; HBG001099; -.
OMA; HYRPVSN; -.
OrthoDB; EOG091G0M7U; -.
TreeFam; TF337236; -.
Reactome; R-BTA-2993913; Clearance of Nuclear Envelope Membranes from Chromatin.
Reactome; R-BTA-2995383; Initiation of Nuclear Envelope Reformation.
Reactome; R-BTA-4419969; Depolymerisation of the Nuclear Lamina.
Proteomes; UP000009136; Chromosome X.
Bgee; ENSBTAG00000022314; Expressed in 9 organ(s), highest expression level in colon.
ExpressionAtlas; Q3SX08; baseline and differential.
GO; GO:0032541; C:cortical endoplasmic reticulum; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005635; C:nuclear envelope; IBA:GO_Central.
GO; GO:0005637; C:nuclear inner membrane; IBA:GO_Central.
GO; GO:0031965; C:nuclear membrane; IBA:GO_Central.
GO; GO:0005640; C:nuclear outer membrane; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0005819; C:spindle; IBA:GO_Central.
GO; GO:0031616; C:spindle pole centrosome; IEA:Ensembl.
GO; GO:0003779; F:actin binding; IBA:GO_Central.
GO; GO:0048487; F:beta-tubulin binding; IBA:GO_Central.
GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Ensembl.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IBA:GO_Central.
GO; GO:0048147; P:negative regulation of fibroblast proliferation; IEA:Ensembl.
GO; GO:0046827; P:positive regulation of protein export from nucleus; IEA:Ensembl.
GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
CDD; cd12939; LEM_emerin; 1.
Gene3D; 1.10.720.40; -; 1.
InterPro; IPR035004; Emerin.
InterPro; IPR011015; LEM/LEM-like_dom_sf.
InterPro; IPR003887; LEM_dom.
InterPro; IPR034989; LEM_emerin.
PANTHER; PTHR15171; PTHR15171; 1.
Pfam; PF03020; LEM; 1.
SMART; SM00540; LEM; 1.
SUPFAM; SSF63451; SSF63451; 1.
PROSITE; PS50954; LEM; 1.
1: Evidence at protein level;
Complete proteome {ECO:0000313|Proteomes:UP000009136};
Membrane {ECO:0000256|SAM:Phobius};
Proteomics identification {ECO:0000213|PeptideAtlas:Q3SX08};
Reference proteome {ECO:0000313|Proteomes:UP000009136};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 228 249 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 1 45 LEM. {ECO:0000259|PROSITE:PS50954}.
SEQUENCE 261 AA; 29471 MW; 7188A25E85672AB0 CRC64;
MDDYAALSDS ELAAVLRQYN IPHGPVVGST RKLYEKKIFE YESQRRRLSP PSSSASSFSY
RFSDLDSASV DSDMYDLPKK EDALLYQSKG YNDDYYEESY LTTRTYGEPE SMGTSKGFRQ
PSASLSDADP FHRQVRDDNL FSLEEEGKDR ERLLYGQDSA YQNIAHYRPI SNISRSSLGL
SYYPTSSSTS SVSSSSSSAP SWLTRRAIRP EKQAPGAAGL GQDRQVPLWG QVLLFLVFAA
FLLFVYYFMQ AEDGNPFWAE P


Related products :

Catalog number Product name Quantity
IQ567 Mouse Anti-Emerin Target Antigen Emerin Host Isotype Mouse IgG1 Application WB, IF 0.1ml (1mg/ml)
LF-MA10097 anti-emerin (3B9), Mouse monoclonal to emerin, Isotype IgG2a, Host Mouse 100 ug
LF-PA40380 anti-Emerin (EMD) , Rabbit polyclonal to Emerin (EMD) , Isotype IgG, Host Rabbit 50 ug
IQ567 Mouse Antibody-Emerin Purification: Protein G Clone: MANEM1(5D10) Host_Isotype: Mouse IgG1 0.1ml (1mg/ml)
AP01159PU-S Emerin 50 µl
AP01160PU-S Emerin 50 µl
AP07749PU-N Emerin 50 µg
AP01159PU-S Emerin 50 µl
AP01160PU-S Emerin 50 µl
ABP-Ri-VAsiD31 emerin 5OD (12.5nmol)
BP4518 Emerin 20 µl
BP4518 Emerin 20 µl
MO20027-100 Emerin 0.1 ml
AP07749PU-N Emerin 50 µg
MO20027-100 Emerin 0.1 ml
AM00583SU-N Emerin 0.5 ml
BP4518 Emerin 20 µl
Z5100048 Emerin 14 nmole
AM00583SU-N Emerin 0.5 ml
Z5100048 Emerin 14 nmole
AP30313PU-N Emerin 0.1 mg
orb74797 Emerin antibody 100 ug
AP17326PU-N Emerin (N_term) 0.1 mg
AP17325PU-N Emerin (C_term) 0.1 mg
4031 Emerin Antibody 0.1 mg


 

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