Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Early growth response protein

 A0MWD2_TAEGU            Unreviewed;       510 AA.
A0MWD2;
12-DEC-2006, integrated into UniProtKB/TrEMBL.
12-DEC-2006, sequence version 1.
05-JUL-2017, entry version 79.
RecName: Full=Early growth response protein {ECO:0000256|RuleBase:RU363046};
Name=zenk {ECO:0000313|EMBL:ABK54358.1};
Synonyms=EGR1 {ECO:0000313|Ensembl:ENSTGUP00000000002};
Taeniopygia guttata (Zebra finch) (Poephila guttata).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea;
Estrildidae; Estrildinae; Taeniopygia.
NCBI_TaxID=59729;
[1] {ECO:0000313|EMBL:ABK54358.1}
NUCLEOTIDE SEQUENCE.
Malcher R., Lovell P.V., Mello C.V.;
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSTGUP00000000002, ECO:0000313|Proteomes:UP000007754}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=20360741; DOI=10.1038/nature08819;
Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C.,
London S.E., Li Y., Lin Y.C., George J., Sweedler J., Southey B.,
Gunaratne P., Watson M., Nam K., Backstrom N., Smeds L., Nabholz B.,
Itoh Y., Whitney O., Pfenning A.R., Howard J., Volker M.,
Skinner B.M., Griffin D.K., Ye L., McLaren W.M., Flicek P.,
Quesada V., Velasco G., Lopez-Otin C., Puente X.S., Olender T.,
Lancet D., Smit A.F., Hubley R., Konkel M.K., Walker J.A.,
Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z., Eichler E.E.,
Stapley J., Slate J., Ekblom R., Birkhead T., Burke T., Burt D.,
Scharff C., Adam I., Richard H., Sultan M., Soldatov A., Lehrach H.,
Edwards S.V., Yang S.P., Li X., Graves T., Fulton L., Nelson J.,
Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
"The genome of a songbird.";
Nature 464:757-762(2010).
[3] {ECO:0000313|Ensembl:ENSTGUP00000000002}
IDENTIFICATION.
Ensembl;
Submitted (JAN-2012) to UniProtKB.
-!- FUNCTION: Transcriptional regulator. Recognizes and binds to the
DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region
of target genes. Binds double-stranded target DNA, irrespective of
the cytosine methylation status. Regulates the transcription of
numerous target genes, and thereby plays an important role in
regulating the response to growth factors, DNA damage, and
ischemia. Plays a role in the regulation of cell survival,
proliferation and cell death. {ECO:0000256|RuleBase:RU363046}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU363046}.
-!- SIMILARITY: Belongs to the EGR C2H2-type zinc-finger protein
family. {ECO:0000256|RuleBase:RU363046}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; ABQF01056820; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; EF052676; ABK54358.1; -; mRNA.
RefSeq; NP_001074426.1; NM_001080957.1.
UniGene; Tgu.4822; -.
Ensembl; ENSTGUT00000000002; ENSTGUP00000000002; ENSTGUG00000000003.
GeneID; 100008579; -.
KEGG; tgu:100008579; -.
CTD; 1958; -.
eggNOG; KOG1721; Eukaryota.
eggNOG; COG5048; LUCA.
GeneTree; ENSGT00550000074455; -.
HOGENOM; HOG000036856; -.
HOVERGEN; HBG003909; -.
KO; K09203; -.
OMA; FATQTGS; -.
OrthoDB; EOG091G06VX; -.
TreeFam; TF318980; -.
Proteomes; UP000007754; Chromosome 13.
GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
GO; GO:0010385; F:double-stranded methylated DNA binding; IEA:Ensembl.
GO; GO:0044729; F:hemi-methylated DNA-binding; IEA:Ensembl.
GO; GO:0035035; F:histone acetyltransferase binding; IEA:Ensembl.
GO; GO:1990841; F:promoter-specific chromatin binding; IEA:Ensembl.
GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IEA:Ensembl.
GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding; IEA:Ensembl.
GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
GO; GO:0030509; P:BMP signaling pathway; IEA:Ensembl.
GO; GO:0071480; P:cellular response to gamma radiation; IEA:Ensembl.
GO; GO:0098759; P:cellular response to interleukin-8; IEA:Ensembl.
GO; GO:0070498; P:interleukin-1-mediated signaling pathway; IEA:Ensembl.
GO; GO:0061743; P:motor learning; IDA:AgBase.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IEA:Ensembl.
GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl.
GO; GO:0045080; P:positive regulation of chemokine biosynthetic process; IEA:Ensembl.
GO; GO:0046886; P:positive regulation of hormone biosynthetic process; IEA:Ensembl.
GO; GO:0050725; P:positive regulation of interleukin-1 beta biosynthetic process; IEA:Ensembl.
GO; GO:0042981; P:regulation of apoptotic process; IEA:Ensembl.
GO; GO:2000182; P:regulation of progesterone biosynthetic process; IEA:Ensembl.
GO; GO:0033233; P:regulation of protein sumoylation; IEA:Ensembl.
GO; GO:0061418; P:regulation of transcription from RNA polymerase II promoter in response to hypoxia; IEA:Ensembl.
GO; GO:0010996; P:response to auditory stimulus; IDA:AgBase.
GO; GO:0009749; P:response to glucose; IEA:Ensembl.
GO; GO:0032868; P:response to insulin; IEA:Ensembl.
GO; GO:0002931; P:response to ischemia; IEA:Ensembl.
GO; GO:0035914; P:skeletal muscle cell differentiation; IEA:Ensembl.
GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
InterPro; IPR021839; DUF3432.
InterPro; IPR021849; DUF3446.
InterPro; IPR013087; Znf_C2H2_type.
Pfam; PF11914; DUF3432; 1.
Pfam; PF11928; DUF3446; 1.
SMART; SM00355; ZnF_C2H2; 3.
SUPFAM; SSF57667; SSF57667; 2.
PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
PROSITE; PS50157; ZINC_FINGER_C2H2_2; 3.
2: Evidence at transcript level;
Activator {ECO:0000256|RuleBase:RU363046};
Complete proteome {ECO:0000313|Proteomes:UP000007754};
DNA-binding {ECO:0000256|RuleBase:RU363046};
Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042,
ECO:0000256|RuleBase:RU363046, ECO:0000313|EMBL:ABK54358.1};
Nucleus {ECO:0000256|RuleBase:RU363046};
Reference proteome {ECO:0000313|Proteomes:UP000007754};
Transcription {ECO:0000256|RuleBase:RU363046};
Transcription regulation {ECO:0000256|RuleBase:RU363046};
Zinc {ECO:0000256|PROSITE-ProRule:PRU00042,
ECO:0000256|RuleBase:RU363046, ECO:0000313|EMBL:ABK54358.1};
Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042,
ECO:0000256|RuleBase:RU363046, ECO:0000313|EMBL:ABK54358.1}.
DOMAIN 311 340 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
DOMAIN 341 368 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
DOMAIN 369 396 C2H2-type. {ECO:0000259|PROSITE:PS50157}.
SEQUENCE 510 AA; 55282 MW; 03700C659B1B8D35 CRC64;
MAAAKAEMQL LPPLQISDPF GAFPHSPPAM DTHYPKLEEM MLLSGGGPQF LAPPGASESA
GFGAAGEPGE QHFEHLGADT FPEISLNNEK TLPETSYPNQ TTRLPPITYT GRFSLEPAPN
SSNPLWPEPL FSLVSGLVGM ANAPPTSTPT SSSPSSSSQS SPLSCSVQAS ENNPIYSAAP
TFPNSSSDIF PESQTQSFPN PSGAPIQYPP PAYPTAKTNF QVPMIPDYLF PQQQAELSLV
PADQKPFPAL ETRAQQPSLT PLSTIKAFAT QTGSQELKTL NANYQSQLIK PSRMRKYPNR
PSKTPPHERP YACPVESCDR RFSRSDELTR HIRIHTGQKP FQCRICMRNF SRSDHLTTHI
RTHTGEKPFA CDICGRKFAR SDERKRHTKI HLRQKDKKVE KAAPASTASP IPAYSSSVTT
SYPSSITTTY PSPVRTAYSS PAPSSYPSPV HTTFPSPSIA TTYPSGTATF QTQVATSFSS
PGVANNFSSQ VTSALSDINS AFSPRTIEIC


Related products :

Catalog number Product name Quantity
EIAAB12630 Early growth response protein 4,Early response protein NGFI-C,Egr4,EGR-4,Egr-4,Nerve growth factor-induced protein C,Ngfic,NGFI-C,Rat,Rattus norvegicus
18-003-43783 Krueppel-like factor 11 - Transforming growth factor-beta-inducible early growth response protein 2; TGFB-inducible early growth response protein 2; TIEG-2 Polyclonal 0.1 mg Protein A
U0688h CLIA EGR-alpha,Homo sapiens,Human,KLF10,Krueppel-like factor 10,TGFB-inducible early growth response protein 1,TIEG,TIEG1,TIEG-1,Transforming growth factor-beta-inducible early growth response protein 96T
U0688r CLIA Cpg20,Klf10,Krueppel-like factor 10,Rat,Rattus norvegicus,TGFB-inducible early growth response protein 1,Tieg,Tieg1,TIEG-1,Transforming growth factor-beta-inducible early growth response protein 96T
E0688r ELISA Cpg20,Klf10,Krueppel-like factor 10,Rat,Rattus norvegicus,TGFB-inducible early growth response protein 1,Tieg,Tieg1,TIEG-1,Transforming growth factor-beta-inducible early growth response protein 96T
E0688h ELISA EGR-alpha,Homo sapiens,Human,KLF10,Krueppel-like factor 10,TGFB-inducible early growth response protein 1,TIEG,TIEG1,TIEG-1,Transforming growth factor-beta-inducible early growth response protei 96T
E0688h ELISA kit EGR-alpha,Homo sapiens,Human,KLF10,Krueppel-like factor 10,TGFB-inducible early growth response protein 1,TIEG,TIEG1,TIEG-1,Transforming growth factor-beta-inducible early growth response p 96T
E0688r ELISA kit Cpg20,Klf10,Krueppel-like factor 10,Rat,Rattus norvegicus,TGFB-inducible early growth response protein 1,Tieg,Tieg1,TIEG-1,Transforming growth factor-beta-inducible early growth response pr 96T
EIAAB24752 Early response 1,Er1,hMi-er1,Homo sapiens,Human,KIAA1610,Mesoderm induction early response protein 1,MIER1,Mi-er1
EIAAB24753 Early response 1,Er1,Kiaa1610,Mesoderm induction early response protein 1,Mier1,Mi-er1,Mouse,Mus musculus
gen10006 KLF10_RAT Transforming growth factor-beta-inducible early growth response protein 1 ELISA tesk kit 1
gen9987 KLF10_HUMAN Transforming growth factor-beta-inducible early growth response protein 1 ELISA tesk kit 1
gen9998 KLF10_MOUSE Transforming growth factor-beta-inducible early growth response protein 1 ELISA tesk kit 1
YBOX1_RAT Rat ELISA Kit FOR Early growth response protein 3 96T
EM999 Early Growth Response Protein 2 Elisa Kit 96T
EH892 Early growth response protein 1 Elisa Kit 96T
E0863b Rat ELISA Kit FOR Early growth response protein 4 96T
CG55 Early growth response protein 1 EGR1 500
CG55 Early growth response protein 1 EGR1 lmg
EM998 Early Growth Response Protein 1 Elisa Kit 96T
CI172_MOUSE Rat ELISA Kit FOR Early growth response protein 3 96T
ER916 Early Growth Response Protein 1 Elisa Kit 96T
E0007h Rat ELISA Kit FOR Early growth response protein 3 96T
E02E0043 Rat Early Growth Response Protein 1 ELISA 96T/kit
ER917 Early Growth Response Protein 2 Elisa Kit 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur