GENTAUR Molecular Products.

 F7CPI5_MONDO            Unreviewed;       248 AA.
 F7CPI5;
 27-JUL-2011, integrated into UniProtKB/TrEMBL.
 27-JUL-2011, sequence version 1.
 12-SEP-2018, entry version 49.
 SubName: Full=Empty spiracles homeobox 2 {ECO:0000313|Ensembl:ENSMODP00000011730};
 Name=EMX2 {ECO:0000313|Ensembl:ENSMODP00000011730};
 Monodelphis domestica (Gray short-tailed opossum).
 Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
 Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
 NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000011730, ECO:0000313|Proteomes:UP000002280};
 [1] {ECO:0000313|Ensembl:ENSMODP00000011730, ECO:0000313|Proteomes:UP000002280}
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
 PubMed=17495919; DOI=10.1038/nature05805;
 Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L.,
 Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J.,
 Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A.,
 Benos P.V., Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L.,
 Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M.,
 Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E.,
 Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M.,
 Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E.,
 Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A.,
 Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J.,
 Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J.,
 Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S.,
 Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A.,
 Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C.,
 Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
 Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P.,
 Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C.,
 Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K.,
 Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D.,
 Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G.,
 Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E.,
 Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C.,
 Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E.,
 Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K.,
 Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A.,
 Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R.,
 Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
 McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
 Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A.,
 Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N.,
 Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S.,
 Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F.,
 Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P.,
 Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D.,
 Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
 Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
 Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
 Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
 Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
 Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
 Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
 Samollow P.B., Lander E.S., Lindblad-Toh K.;
 "Genome of the marsupial Monodelphis domestica reveals innovation in
 non-coding sequences.";
 Nature 447:167-177(2007).
 [2] {ECO:0000313|Ensembl:ENSMODP00000011730}
 IDENTIFICATION.
 Ensembl;
 Submitted (JUL-2011) to UniProtKB.
 -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
     ProRule:PRU00108, ECO:0000256|RuleBase:RU000682,
     ECO:0000256|SAAS:SAAS00860360}.
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 RefSeq; XP_001368074.1; XM_001368037.3.
 ProteinModelPortal; F7CPI5; -.
 STRING; 13616.ENSMODP00000011730; -.
 Ensembl; ENSMODT00000011951; ENSMODP00000011730; ENSMODG00000009388.
 GeneID; 100020634; -.
 KEGG; mdo:100020634; -.
 CTD; 2018; -.
 eggNOG; KOG0843; Eukaryota.
 eggNOG; ENOG4111SRW; LUCA.
 GeneTree; ENSGT00910000144043; -.
 InParanoid; F7CPI5; -.
 KO; K09317; -.
 OrthoDB; EOG091G0P41; -.
 TreeFam; TF317015; -.
 Proteomes; UP000002280; Chromosome 1.
 Bgee; ENSMODG00000009388; Expressed in 5 organ(s), highest expression level in female gonad.
 GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO; GO:0009952; P:anterior/posterior pattern specification; IEA:Ensembl.
 GO; GO:0021846; P:cell proliferation in forebrain; IEA:Ensembl.
 GO; GO:0021796; P:cerebral cortex regionalization; IEA:Ensembl.
 GO; GO:0021542; P:dentate gyrus development; IEA:Ensembl.
 GO; GO:0021885; P:forebrain cell migration; IEA:Ensembl.
 GO; GO:0030182; P:neuron differentiation; IEA:Ensembl.
 GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
 GO; GO:0072001; P:renal system development; IEA:Ensembl.
 GO; GO:0042493; P:response to drug; IEA:Ensembl.
 CDD; cd00086; homeodomain; 1.
 InterPro; IPR009057; Homeobox-like_sf.
 InterPro; IPR017970; Homeobox_CS.
 InterPro; IPR001356; Homeobox_dom.
 InterPro; IPR020479; Homeobox_metazoa.
 InterPro; IPR000047; HTH_motif.
 Pfam; PF00046; Homeobox; 1.
 PRINTS; PR00024; HOMEOBOX.
 PRINTS; PR00031; HTHREPRESSR.
 SMART; SM00389; HOX; 1.
 SUPFAM; SSF46689; SSF46689; 1.
 PROSITE; PS00027; HOMEOBOX_1; 1.
 PROSITE; PS50071; HOMEOBOX_2; 1.
 4: Predicted;
 Complete proteome {ECO:0000313|Proteomes:UP000002280};
 DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
 ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860283};
 Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
 ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860291};
 Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
 ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860284};
 Reference proteome {ECO:0000313|Proteomes:UP000002280}.
 DOMAIN      148    208       Homeobox. {ECO:0000259|PROSITE:PS50071}.
 DNA_BIND    150    209       Homeobox. {ECO:0000256|PROSITE-
                              ProRule:PRU00108}.
 SEQUENCE   248 AA;  28074 MW;  CD20164E51D4D14F CRC64;
 MFQPAPKRCF TIESLVAKDN PLPASRSEDP IRPAALSYAN SSPINPFLNG FHTAAGRGVY
 SNPDLVFAEA VSHPPNPAVP VHPVPPPHAL AAHPLPSSHS PHPLFASQQR DPSTFYPWLI
 HRYRYLGHRF QGNETSPESF LLHNALARKP KRIRTAFSPS QLLRLEHAFE KNHYVVGAER
 KQLAHSLSLT ETQVKVWFQN RRTKFKRQKL EEEGSDSQQK KKGTHHINRW RIATKQASPE
 EIDVTSDD

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