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Empty spiracles homeobox 2 (Emx2 protein)

 B5DFT1_XENTR            Unreviewed;       247 AA.
B5DFT1;
14-OCT-2008, integrated into UniProtKB/TrEMBL.
14-OCT-2008, sequence version 1.
12-SEP-2018, entry version 82.
SubName: Full=Empty spiracles homeobox 2 {ECO:0000313|Ensembl:ENSXETP00000047776};
SubName: Full=Emx2 protein {ECO:0000313|EMBL:AAI69182.1};
Name=emx2 {ECO:0000313|EMBL:AAI69182.1,
ECO:0000313|Ensembl:ENSXETP00000047776,
ECO:0000313|Xenbase:XB-GENE-481028};
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
Silurana.
NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI69182.1};
[1] {ECO:0000313|EMBL:AAI69182.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=PopA {ECO:0000313|EMBL:AAI69182.1};
TISSUE=Whole {ECO:0000313|EMBL:AAI69182.1};
NIH - Xenopus Gene Collection (XGC) project;
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSXETP00000047776}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000047776};
PubMed=20431018; DOI=10.1126/science.1183670;
Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
Rokhsar D.S.;
"The genome of the Western clawed frog Xenopus tropicalis.";
Science 328:633-636(2010).
[3] {ECO:0000313|Ensembl:ENSXETP00000047776}
IDENTIFICATION.
Ensembl;
Submitted (JUN-2011) to UniProtKB.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU000682,
ECO:0000256|SAAS:SAAS00860360}.
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EMBL; AAMC01136896; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AAMC01136897; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; AAMC01136898; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; BC169182; AAI69182.1; -; mRNA.
RefSeq; NP_001128284.1; NM_001134812.1.
UniGene; Str.55611; -.
STRING; 8364.ENSXETP00000047776; -.
Ensembl; ENSXETT00000047776; ENSXETP00000047776; ENSXETG00000022080.
GeneID; 100038069; -.
KEGG; xtr:100038069; -.
CTD; 2018; -.
Xenbase; XB-GENE-481028; emx2.
eggNOG; KOG0843; Eukaryota.
eggNOG; ENOG4111SRW; LUCA.
GeneTree; ENSGT00910000144043; -.
HOGENOM; HOG000247032; -.
HOVERGEN; HBG005024; -.
KO; K09317; -.
OMA; FQPTPKR; -.
OrthoDB; EOG091G0P41; -.
TreeFam; TF317015; -.
Proteomes; UP000008143; Unassembled WGS sequence.
Bgee; ENSXETG00000022080; Expressed in 10 organ(s), highest expression level in embryo.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO; GO:0007420; P:brain development; IEA:Ensembl.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
GO; GO:0060121; P:vestibular receptor cell stereocilium organization; IEA:Ensembl.
CDD; cd00086; homeodomain; 1.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR017970; Homeobox_CS.
InterPro; IPR001356; Homeobox_dom.
InterPro; IPR020479; Homeobox_metazoa.
InterPro; IPR000047; HTH_motif.
Pfam; PF00046; Homeobox; 1.
PRINTS; PR00024; HOMEOBOX.
PRINTS; PR00031; HTHREPRESSR.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00027; HOMEOBOX_1; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
2: Evidence at transcript level;
Complete proteome {ECO:0000313|Proteomes:UP000008143};
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860283};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860291};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860284};
Reference proteome {ECO:0000313|Proteomes:UP000008143}.
DOMAIN 147 207 Homeobox. {ECO:0000259|PROSITE:PS50071}.
DNA_BIND 149 208 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 247 AA; 27979 MW; BBE397769B34D7FC CRC64;
MFQPTPKRCF TIESLVAKDS PLPVSRSEEP IRPAALSYAN SAPMNPFLNG FHPTGRGVYS
NPDLVFAEAV SHPPNPAVPV HPVPPPHALA AHPLPTSHSP HPLFASQQRD PSTFYPWLIH
RYRYLGHRFQ GNDTSAESFL LHNALARKPK RIRTAFSPSQ LLRLEHAFEK NHYVVGAERK
QLAHSLSLTE TQVKVWFQNR RTKFKRQKLE EEGSDSSQKK KGAHHINRWR LATKQASPEE
IDVTSDD


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