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Empty spiracles homeobox 2 (Emx2 protein)

 Q568U8_DANRE            Unreviewed;       247 AA.
Q568U8;
10-MAY-2005, integrated into UniProtKB/TrEMBL.
10-MAY-2005, sequence version 1.
28-MAR-2018, entry version 107.
SubName: Full=Empty spiracles homeobox 2 {ECO:0000313|EMBL:AAH92713.1};
SubName: Full=Emx2 protein {ECO:0000313|EMBL:AAI65103.1};
Name=emx2 {ECO:0000313|EMBL:AAH92713.1,
ECO:0000313|ZFIN:ZDB-GENE-990415-54};
Danio rerio (Zebrafish) (Brachydanio rerio).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
Cyprinidae; Danio.
NCBI_TaxID=7955 {ECO:0000313|EMBL:AAH92713.1};
[1] {ECO:0000313|EMBL:AAH92713.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Olfactory epithelium {ECO:0000313|EMBL:AAH92713.1};
NIH - Zebrafish Gene Collection (ZGC) project;
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:AAI65103.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=PCR rescue {ECO:0000313|EMBL:AAI65103.1};
NIH - Zebrafish Gene Collection (ZGC) project;
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-
ProRule:PRU00108, ECO:0000256|RuleBase:RU000682,
ECO:0000256|SAAS:SAAS00860360}.
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EMBL; BC092713; AAH92713.1; -; mRNA.
EMBL; BC165103; AAI65103.1; -; mRNA.
RefSeq; NP_571355.2; NM_131280.2.
UniGene; Dr.75105; -.
GeneID; 30537; -.
KEGG; dre:30537; -.
CTD; 2018; -.
ZFIN; ZDB-GENE-990415-54; emx2.
eggNOG; KOG0843; Eukaryota.
eggNOG; ENOG4111SRW; LUCA.
HOGENOM; HOG000247032; -.
HOVERGEN; HBG005024; -.
KO; K09317; -.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
GO; GO:0007420; P:brain development; IEP:ZFIN.
GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
GO; GO:0060121; P:vestibular receptor cell stereocilium organization; IMP:ZFIN.
CDD; cd00086; homeodomain; 1.
InterPro; IPR009057; Homeobox-like_sf.
InterPro; IPR017970; Homeobox_CS.
InterPro; IPR001356; Homeobox_dom.
InterPro; IPR020479; Homeobox_metazoa.
InterPro; IPR000047; HTH_motif.
Pfam; PF00046; Homeobox; 1.
PRINTS; PR00024; HOMEOBOX.
PRINTS; PR00031; HTHREPRESSR.
SMART; SM00389; HOX; 1.
SUPFAM; SSF46689; SSF46689; 1.
PROSITE; PS00027; HOMEOBOX_1; 1.
PROSITE; PS50071; HOMEOBOX_2; 1.
2: Evidence at transcript level;
DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860283,
ECO:0000313|EMBL:AAH92713.1};
Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860291,
ECO:0000313|EMBL:AAH92713.1};
Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
ECO:0000256|RuleBase:RU000682, ECO:0000256|SAAS:SAAS00860284}.
DOMAIN 147 207 Homeobox. {ECO:0000259|PROSITE:PS50071}.
DNA_BIND 149 208 Homeobox. {ECO:0000256|PROSITE-
ProRule:PRU00108}.
SEQUENCE 247 AA; 28012 MW; 9D892112A25188AC CRC64;
MFQPTPKRCF TIESLVAKDN PLPSSRSEEP IRPAALSYAN SSQMNPFLNG FHSSGRGVYS
NPGLVFAEAV SHPPNSAVPV HSVPPPHALA AHPLSSSHSP HPLFASQQRD PSTFYPWLIH
RYRYLGHRFQ GNETSPESFL LHNALARKPK RIRTAFSPSQ LLRLEHAFEK NHYVVGAERK
QLAHSLSLTE TQVKVWFQNR RTKFKRQKLE EEGSDSQQKK KGTHHINRWR LATKQGSPEE
IDVTSDD


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