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Endonuclease G

 G3UKE6_LOXAF            Unreviewed;       226 AA.
G3UKE6;
16-NOV-2011, integrated into UniProtKB/TrEMBL.
16-NOV-2011, sequence version 1.
30-AUG-2017, entry version 29.
SubName: Full=Endonuclease G {ECO:0000313|Ensembl:ENSLAFP00000028305};
Name=ENDOG {ECO:0000313|Ensembl:ENSLAFP00000028305};
Loxodonta africana (African elephant).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000028305};
[1] {ECO:0000313|Ensembl:ENSLAFP00000028305}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000028305};
Di Palma F., Heiman D., Young S., Johnson J., Lander E.S.,
Lindblad-Toh K.;
"The Genome Sequence of Loxodonta africana (African elephant).";
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSLAFP00000028305}
IDENTIFICATION.
STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000028305};
Ensembl;
Submitted (SEP-2011) to UniProtKB.
-!- CAUTION: The sequence shown here is derived from an Ensembl
automatic analysis pipeline and should be considered as
preliminary data. {ECO:0000313|Ensembl:ENSLAFP00000028305}.
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STRING; 9785.ENSLAFP00000028305; -.
Ensembl; ENSLAFT00000025333; ENSLAFP00000028305; ENSLAFG00000028267.
eggNOG; KOG3721; Eukaryota.
eggNOG; COG1864; LUCA.
GeneTree; ENSGT00530000063772; -.
InParanoid; G3UKE6; -.
OMA; HSEEAMA; -.
OrthoDB; EOG091G0BHG; -.
TreeFam; TF105386; -.
Proteomes; UP000007646; Unassembled WGS sequence.
GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
GO; GO:0046872; F:metal ion binding; IEA:InterPro.
GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO; GO:0006309; P:apoptotic DNA fragmentation; IEA:Ensembl.
GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
GO; GO:0046677; P:response to antibiotic; IEA:Ensembl.
GO; GO:0034612; P:response to tumor necrosis factor; IEA:Ensembl.
InterPro; IPR018524; DNA/RNA_endonuclease_AS.
InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease.
InterPro; IPR020821; Extracellular_endonuc_su_A.
Pfam; PF01223; Endonuclease_NS; 1.
SMART; SM00892; Endonuclease_NS; 1.
SMART; SM00477; NUC; 1.
PROSITE; PS01070; NUCLEASE_NON_SPEC; 1.
4: Predicted;
Complete proteome {ECO:0000313|Proteomes:UP000007646};
Reference proteome {ECO:0000313|Proteomes:UP000007646};
Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1 19 {ECO:0000256|SAM:SignalP}.
CHAIN 20 226 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5003456348.
DOMAIN 1 214 NUC. {ECO:0000259|SMART:SM00477}.
DOMAIN 4 214 Endonuclease_NS.
{ECO:0000259|SMART:SM00892}.
SEQUENCE 226 AA; 24375 MW; E2FE5E0C00B90F96 CRC64;
MRALRAGLTL ALGAGLGAAA EGWRRRRADA RAARGLLGPA ARAARGGGGR APRPCLRDLA
GSSGFDRGHL AAAANHRWSQ KAMDDTFYLS NVAPQVVPHL NQNAWNNLEK YSRSLTRTYQ
NVYVCTGPLF LPRTEADGKS YVKYQVIGKN HVAVPTHFFK VLILEAASGQ IELRSYVMPN
ATVDEAIPLE RFLVPIESIE RASGLLFVPN ILARGGSLKA ITAGSK


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