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Envelope glycoprotein (Fragment)

 Q09NK5_9HIV1            Unreviewed;       279 AA.
Q09NK5;
17-OCT-2006, integrated into UniProtKB/TrEMBL.
17-OCT-2006, sequence version 1.
25-OCT-2017, entry version 39.
SubName: Full=Envelope glycoprotein {ECO:0000313|EMBL:ABI52344.1};
Flags: Fragment;
Name=env {ECO:0000313|EMBL:ABI52344.1};
Human immunodeficiency virus 1.
Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae;
Lentivirus; Primate lentivirus group.
NCBI_TaxID=11676 {ECO:0000313|EMBL:ABI52344.1};
NCBI_TaxID=9606; Homo sapiens (Human).
[1] {ECO:0000313|EMBL:ABI52344.1}
NUCLEOTIDE SEQUENCE.
STRAIN=1396V2 {ECO:0000313|EMBL:ABI52344.1};
PubMed=17056765; DOI=10.1189/jlb.0306144;
Llewellyn N., Zioni R., Zhu H., Andrus T., Xu Y., Corey L., Zhu T.;
"Continued evolution of HIV-1 circulating in blood monocytes with
antiretroviral therapy: genetic analysis of HIV-1 in monocytes and
CD4+ T cells of patients with discontinued therapy.";
J. Leukoc. Biol. 80:1118-1126(2006).
-!- SUBCELLULAR LOCATION: Virion membrane
{ECO:0000256|SAAS:SAAS00592067}.
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EMBL; DQ853306; ABI52344.1; -; Genomic_DNA.
GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW.
GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell.
GO; GO:0039663; P:membrane fusion involved in viral entry into host cell; IEA:UniProtKB-KW.
GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW.
Gene3D; 2.170.40.20; -; 1.
InterPro; IPR036377; Gp120_core_sf.
InterPro; IPR000777; HIV1_Gp120.
Pfam; PF00516; GP120; 1.
SUPFAM; SSF56502; SSF56502; 1.
4: Predicted;
Coiled coil {ECO:0000256|SAM:Coils};
Disulfide bond {ECO:0000256|SAAS:SAAS00881052};
Fusion of virus membrane with host membrane
{ECO:0000256|SAAS:SAAS00487637};
Host-virus interaction {ECO:0000256|SAAS:SAAS00486387};
Membrane {ECO:0000256|SAAS:SAAS00880960};
Viral attachment to host cell {ECO:0000256|SAAS:SAAS00486387};
Viral envelope protein {ECO:0000313|EMBL:ABI52344.1};
Viral penetration into host cytoplasm {ECO:0000256|SAAS:SAAS00487637};
Virion {ECO:0000256|SAAS:SAAS00486387, ECO:0000313|EMBL:ABI52344.1};
Virus entry into host cell {ECO:0000256|SAAS:SAAS00486387,
ECO:0000256|SAAS:SAAS00487637}.
DOMAIN 1 269 GP120. {ECO:0000259|Pfam:PF00516}.
COILED 91 118 {ECO:0000256|SAM:Coils}.
NON_TER 1 1 {ECO:0000313|EMBL:ABI52344.1}.
NON_TER 279 279 {ECO:0000313|EMBL:ABI52344.1}.
SEQUENCE 279 AA; 31275 MW; 4F174D9201A70567 CRC64;
THGIRPVVST QLLLNGSLAE EEVVIRSQNF SDNAKTIIVQ LKDPVEINCT RPNNNTRKSI
PIGPGRAFYA TGDIIGDIRR AHCNISGAKW NNTLQQVVKK LKEQFERLNK TIKTINFTQP
SGGDPEIVMH IFNCGGEFFY CNTTNLFSST WNLTQPLNNT WNETIGPNDT ITLQCRIKQI
VNMWQEVGKA MYAPPISGQI RCSSNITGLL LTRDGGHNVT NETETFRPGG GDMRDNWRSE
LYKYKIVKIE PLGIAPTKAR RRVVQREKRA VGIGAMFLG


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