Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Epiphycan (Dermatan sulfate proteoglycan 3) (Proteoglycan-Lb) (PG-Lb) (Small chondroitin/dermatan sulfate proteoglycan)

 EPYC_HUMAN              Reviewed;         322 AA.
Q99645; A8K3M7; Q8NEJ5;
08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
03-APR-2007, sequence version 3.
27-SEP-2017, entry version 155.
RecName: Full=Epiphycan;
AltName: Full=Dermatan sulfate proteoglycan 3;
AltName: Full=Proteoglycan-Lb;
Short=PG-Lb;
AltName: Full=Small chondroitin/dermatan sulfate proteoglycan;
Flags: Precursor;
Name=EPYC; Synonyms=DSPG3, PGLB, SLRR3B;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Chondrocyte;
PubMed=8975717; DOI=10.1006/geno.1996.0643;
Deere M., Johnson H.J., Garza S., Harrison W.R., Yoon S.-J.,
Elder F.F.B., Kucherlapati R., Hoeoek M., Hecht J.T.;
"Characterization of human DSPG3, a small dermatan sulfate
proteoglycan.";
Genomics 38:399-404(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Embryo;
PubMed=14702039; DOI=10.1038/ng1285;
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
"Complete sequencing and characterization of 21,243 full-length human
cDNAs.";
Nat. Genet. 36:40-45(2004).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
Venter J.C.;
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Placenta;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA
project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
-!- FUNCTION: May have a role in bone formation and also in
establishing the ordered structure of cartilage through matrix
organization.
-!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
matrix {ECO:0000250}.
-!- TISSUE SPECIFICITY: Cartilage, ligament, and placenta.
{ECO:0000269|PubMed:8975717}.
-!- PTM: The O-linked polysaccharides on Thr-60 and Ser-96 are
probably the mucin type linked to GalNAc. There is one
glycosaminoglycan chain, known to be dermatan sulfate, and it is
probably the O-glycosylation at Ser-64 (By similarity).
{ECO:0000250}.
-!- SIMILARITY: Belongs to the small leucine-rich proteoglycan (SLRP)
family. SLRP class III subfamily. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; U59111; AAC50945.1; -; mRNA.
EMBL; AK290642; BAF83331.1; -; mRNA.
EMBL; CH471054; EAW97444.1; -; Genomic_DNA.
EMBL; BC030958; AAH30958.1; -; mRNA.
CCDS; CCDS31870.1; -.
RefSeq; NP_004941.2; NM_004950.4.
UniGene; Hs.435680; -.
ProteinModelPortal; Q99645; -.
BioGrid; 108167; 2.
IntAct; Q99645; 2.
STRING; 9606.ENSP00000261172; -.
iPTMnet; Q99645; -.
PhosphoSitePlus; Q99645; -.
BioMuta; EPYC; -.
DMDM; 143811386; -.
PaxDb; Q99645; -.
PeptideAtlas; Q99645; -.
PRIDE; Q99645; -.
DNASU; 1833; -.
Ensembl; ENST00000261172; ENSP00000261172; ENSG00000083782.
GeneID; 1833; -.
KEGG; hsa:1833; -.
UCSC; uc001tbk.3; human.
CTD; 1833; -.
DisGeNET; 1833; -.
EuPathDB; HostDB:ENSG00000083782.7; -.
GeneCards; EPYC; -.
HGNC; HGNC:3053; EPYC.
HPA; HPA038212; -.
HPA; HPA045455; -.
MIM; 601657; gene.
neXtProt; NX_Q99645; -.
OpenTargets; ENSG00000083782; -.
PharmGKB; PA162385144; -.
eggNOG; KOG0619; Eukaryota.
eggNOG; COG4886; LUCA.
GeneTree; ENSGT00730000110781; -.
HOGENOM; HOG000273909; -.
HOVERGEN; HBG006850; -.
InParanoid; Q99645; -.
KO; K08127; -.
OMA; CDDHELD; -.
OrthoDB; EOG091G0C68; -.
PhylomeDB; Q99645; -.
TreeFam; TF351924; -.
GenomeRNAi; 1833; -.
PRO; PR:Q99645; -.
Proteomes; UP000005640; Chromosome 12.
Bgee; ENSG00000083782; -.
CleanEx; HS_EPYC; -.
ExpressionAtlas; Q99645; baseline and differential.
Genevisible; Q99645; HS.
GO; GO:0005615; C:extracellular space; IBA:GO_Central.
GO; GO:0005578; C:proteinaceous extracellular matrix; IBA:GO_Central.
GO; GO:0005539; F:glycosaminoglycan binding; TAS:ProtInc.
GO; GO:0007409; P:axonogenesis; IBA:GO_Central.
GO; GO:0007565; P:female pregnancy; TAS:ProtInc.
Gene3D; 3.80.10.10; -; 2.
InterPro; IPR027217; Epiphycan.
InterPro; IPR032675; L_dom-like.
InterPro; IPR001611; Leu-rich_rpt.
InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
InterPro; IPR000372; LRRNT.
PANTHER; PTHR24373:SF219; PTHR24373:SF219; 1.
Pfam; PF13855; LRR_8; 1.
SMART; SM00369; LRR_TYP; 4.
SMART; SM00013; LRRNT; 1.
SUPFAM; SSF52058; SSF52058; 1.
PROSITE; PS51450; LRR; 4.
2: Evidence at transcript level;
Complete proteome; Disulfide bond; Extracellular matrix; Glycoprotein;
Leucine-rich repeat; Polymorphism; Proteoglycan; Reference proteome;
Repeat; Secreted; Signal.
SIGNAL 1 19 {ECO:0000255}.
CHAIN 20 322 Epiphycan.
/FTId=PRO_0000032768.
DOMAIN 106 143 LRRNT.
REPEAT 144 165 LRR 1.
REPEAT 168 189 LRR 2.
REPEAT 192 213 LRR 3.
REPEAT 238 258 LRR 4.
REPEAT 259 280 LRR 5.
REPEAT 290 310 LRR 6.
COMPBIAS 81 87 Poly-Glu.
CARBOHYD 60 60 O-linked (GalNAc...) threonine.
{ECO:0000250}.
CARBOHYD 64 64 O-linked (Xyl...) (dermatan sulfate)
serine. {ECO:0000250}.
CARBOHYD 96 96 O-linked (GalNAc...) serine.
{ECO:0000250}.
CARBOHYD 283 283 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 302 302 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 118 130 {ECO:0000250}.
DISULFID 279 312 {ECO:0000250}.
VARIANT 150 150 S -> C (in dbSNP:rs17784152).
/FTId=VAR_031595.
CONFLICT 14 14 F -> L (in Ref. 1; AAC50945).
{ECO:0000305}.
CONFLICT 52 52 D -> G (in Ref. 4; AAH30958).
{ECO:0000305}.
CONFLICT 120 120 L -> W (in Ref. 1; AAC50945).
{ECO:0000305}.
CONFLICT 213 213 L -> S (in Ref. 1; AAC50945).
{ECO:0000305}.
CONFLICT 281 281 V -> G (in Ref. 1; AAC50945).
{ECO:0000305}.
SEQUENCE 322 AA; 36637 MW; E11061A38AA7240E CRC64;
MKTLAGLVLG LVIFDAAVTA PTLESINYDS ETYDATLEDL DNLYNYENIP VDKVEIEIAT
VMPSGNRELL TPPPQPEKAQ EEEEEEESTP RLIDGSSPQE PEFTGVLGPH TNEDFPTCLL
CTCISTTVYC DDHELDAIPP LPKNTAYFYS RFNRIKKINK NDFASLSDLK RIDLTSNLIS
EIDEDAFRKL PQLRELVLRD NKIRQLPELP TTLTFIDISN NRLGRKGIKQ EAFKDMYDLH
HLYLTDNNLD HIPLPLPENL RALHLQNNNI LEMHEDTFCN VKNLTYIRKA LEDIRLDGNP
INLSKTPQAY MCLPRLPVGS LV


Related products :

Catalog number Product name Quantity
EIAAB13149 Bos taurus,Bovine,Dermatan sulfate proteoglycan 3,DSPG3,Epiphycan,EPYC,PGLB,PG-Lb,Proteoglycan-Lb,Small chondroitin_dermatan sulfate proteoglycan
EIAAB13151 Dermatan sulfate proteoglycan 3,Dspg3,Epiphycan,Epyc,Mouse,Mus musculus,Pglb,PG-Lb,Proteoglycan-Lb,Small chondroitin_dermatan sulfate proteoglycan
EIAAB13150 Dermatan sulfate proteoglycan 3,DSPG3,Epiphycan,EPYC,Homo sapiens,Human,PGLB,PG-Lb,Proteoglycan-Lb,SLRR3B,Small chondroitin_dermatan sulfate proteoglycan
EIAAB13148 Chicken,Dermatan sulfate proteoglycan 3,DSPG3,Epiphycan,EPYC,Gallus gallus,PGLB,PG-Lb,Proteoglycan-Lb,Small chondroitin_dermatan sulfate proteoglycan
EIAAB09627 Chondroitin sulfate proteoglycan 4,Chondroitin sulfate proteoglycan NG2,CSPG4,Homo sapiens,Human,MCSP,Melanoma chondroitin sulfate proteoglycan,Melanoma-associated chondroitin sulfate proteoglycan
EIAAB30782 Bone proteoglycan II,Dcn,Decorin,Dermatan sulfate proteoglycan-II,DSPG,PG40,PG-S2,Rat,Rattus norvegicus
E1817r ELISA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,Rat,Rattus norvegicus,Vcan 96T
U1817r CLIA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,Rat,Rattus norvegicus,Vcan, 96T
E1817b ELISA kit Bos taurus,Bovine,Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,VCAN,Ver 96T
U1817r CLIA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,Rat,Rattus norvegicus,Vcan,Versi 96T
E1817b ELISA Bos taurus,Bovine,Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,VCAN,Versican 96T
U1817b CLIA kit Bos taurus,Bovine,Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,VCAN,Vers 96T
E1817r ELISA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,Rat,Rattus norvegicus,Vcan,Vers 96T
U1817h CLIA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Homo sapiens,Human,Large fibroblast proteoglycan,PG-M,VCAN,Ver 96T
U1817b CLIA Bos taurus,Bovine,Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Large fibroblast proteoglycan,PG-M,VCAN,Versican 96T
E1817h ELISA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Homo sapiens,Human,Large fibroblast proteoglycan,PG-M,VCAN,Ve 96T
E1817h ELISA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Homo sapiens,Human,Large fibroblast proteoglycan,PG-M,VCAN,Versica 96T
U1817h CLIA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,CSPG2,GHAP,Glial hyaluronate-binding protein,Homo sapiens,Human,Large fibroblast proteoglycan,PG-M,VCAN,Versican 96T
EIAAB09628 An2,Chondroitin sulfate proteoglycan 4,Chondroitin sulfate proteoglycan NG2,Cspg4,Kiaa4232,Mouse,Mus musculus,Ng2,Proteoglycan AN2
U1817m CLIA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
E1817m ELISA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
U1817m CLIA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
E1817m ELISA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
EIAAB09629 Chondroitin sulfate proteoglycan 4,Chondroitin sulfate proteoglycan NG2,Cspg4,HSN tumor-specific antigen,Ng2,Rat,Rattus norvegicus
U1908h CLIA ACAN,AGC1,Aggrecan core protein,Cartilage-specific proteoglycan core protein,Chondroitin sulfate proteoglycan 1,Chondroitin sulfate proteoglycan core protein 1,CSPCP,CSPG1,Homo sapiens,Human,MSK1 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur