Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Esterase-5B (Est-5B) (EC 3.1.1.1) (Carboxylic-ester hydrolase 5B) (Carboxylesterase-5B)

 EST5B_DROPS             Reviewed;         545 AA.
P25726; Q27614; Q27615; Q27616; Q27617; Q27618; Q27619; Q27620;
Q27621; Q27622; Q27623; Q27624; Q27625; Q27626; Q27627; Q27628;
Q27629;
01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
01-MAR-2005, sequence version 2.
30-AUG-2017, entry version 93.
RecName: Full=Esterase-5B;
Short=Est-5B;
EC=3.1.1.1;
AltName: Full=Carboxylic-ester hydrolase 5B;
Short=Carboxylesterase-5B;
Flags: Precursor;
Name=Est-5B; Synonyms=Est5b; ORFNames=GA14349;
Drosophila pseudoobscura pseudoobscura (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=46245;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=2178209;
Brady J.P., Richmond R.C., Oakeshott J.G.;
"Cloning of the esterase-5 locus from Drosophila pseudoobscura and
comparison with its homologue in D. melanogaster.";
Mol. Biol. Evol. 7:525-546(1990).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=GB-115, GB-139, GB-329, GB-336, GB-4, GB-8, JR-106, JR-126,
JR-142, JR-198, JR-32, JR-341, JR-38, JR-382, JR-460, and JR-50;
PubMed=8536974;
Veuille M., King L.M.;
"Molecular bases of polymorphism at the esterase-5B locus in
Drosophila pseudoobscura.";
Genetics 141:255-262(1995).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MV2-25 / Tucson 14011-0121.94;
PubMed=15632085; DOI=10.1101/gr.3059305;
Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S.,
Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P.,
Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J.,
van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E.,
Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D.,
Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D.,
Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R.,
Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L.,
Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F.,
Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M.,
Weinstock G.M., Gibbs R.A.;
"Comparative genome sequencing of Drosophila pseudoobscura:
chromosomal, gene, and cis-element evolution.";
Genome Res. 15:1-18(2005).
-!- CATALYTIC ACTIVITY: A carboxylic ester + H(2)O = an alcohol + a
carboxylate. {ECO:0000255|PROSITE-ProRule:PRU10039}.
-!- SUBUNIT: Homodimer.
-!- SUBCELLULAR LOCATION: Secreted.
-!- TISSUE SPECIFICITY: Eye and hemolymph.
-!- DEVELOPMENTAL STAGE: Expressed throughout development.
-!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
{ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; M55907; AAA28515.1; -; Genomic_DNA.
EMBL; X89085; CAA61457.1; -; Genomic_DNA.
EMBL; X89086; CAA61458.1; -; Genomic_DNA.
EMBL; X89087; CAA61459.1; -; Genomic_DNA.
EMBL; X89088; CAA61460.1; -; Genomic_DNA.
EMBL; X89089; CAA61461.1; -; Genomic_DNA.
EMBL; X89090; CAA61462.1; -; Genomic_DNA.
EMBL; X89091; CAA61463.1; -; Genomic_DNA.
EMBL; X89092; CAA61464.1; -; Genomic_DNA.
EMBL; X89093; CAA61465.1; -; Genomic_DNA.
EMBL; X89094; CAA61466.1; -; Genomic_DNA.
EMBL; X89095; CAA61467.1; -; Genomic_DNA.
EMBL; X89096; CAA61468.1; -; Genomic_DNA.
EMBL; X89097; CAA61469.1; -; Genomic_DNA.
EMBL; X89098; CAA61470.1; -; Genomic_DNA.
EMBL; X89099; CAA61471.1; -; Genomic_DNA.
EMBL; X89100; CAA61472.1; -; Genomic_DNA.
EMBL; CH379069; -; NOT_ANNOTATED_CDS; Genomic_DNA.
PIR; S58968; S58968.
PIR; S58969; S58969.
PIR; S58970; S58970.
PIR; S58971; S58971.
PIR; S58972; S58972.
PIR; S58973; S58973.
PIR; S58974; S58974.
PIR; S58975; S58975.
PIR; S58976; S58976.
PIR; S58977; S58977.
PIR; S58978; S58978.
PIR; S58979; S58979.
PIR; S58980; S58980.
PIR; S58981; S58981.
PIR; S58982; S58982.
PIR; S58983; S58983.
ProteinModelPortal; P25726; -.
SMR; P25726; -.
STRING; 7237.FBpp0274978; -.
ESTHER; drops-est5b; Carb_B_Arthropoda.
MEROPS; S09.947; -.
FlyBase; FBgn0243549; Dpse\Est-5B.
InParanoid; P25726; -.
Proteomes; UP000001819; Partially assembled WGS sequence.
GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
Gene3D; 3.40.50.1820; -; 1.
InterPro; IPR029058; AB_hydrolase.
InterPro; IPR002018; CarbesteraseB.
InterPro; IPR019826; Carboxylesterase_B_AS.
InterPro; IPR019819; Carboxylesterase_B_CS.
Pfam; PF00135; COesterase; 1.
SUPFAM; SSF53474; SSF53474; 1.
PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
2: Evidence at transcript level;
Complete proteome; Disulfide bond; Glycoprotein; Hydrolase;
Polymorphism; Reference proteome; Secreted; Serine esterase; Signal.
SIGNAL 1 19 {ECO:0000255}.
CHAIN 20 545 Esterase-5B.
/FTId=PRO_0000008557.
ACT_SITE 207 207 Acyl-ester intermediate.
{ECO:0000255|PROSITE-ProRule:PRU10039}.
ACT_SITE 467 467 Charge relay system. {ECO:0000250}.
CARBOHYD 113 113 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 421 421 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 507 507 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 84 103 {ECO:0000250}.
DISULFID 259 271 {ECO:0000250}.
DISULFID 515 536 {ECO:0000255}.
VARIANT 4 4 A -> T (in strain: JR-341).
VARIANT 10 10 L -> W (in strain: JR-142 and JR-460).
VARIANT 18 18 S -> F (in strain: GB-8 and JR-50).
VARIANT 23 23 A -> V (in strain: GB-115, GB-336, JR-38,
JR-106, JR-198 and JR-382).
VARIANT 24 24 D -> Y (in strain: GB-336).
VARIANT 26 26 L -> M (in strain: GB-4, JR-126 and JR-
460).
VARIANT 83 83 L -> T (in strain: JR-198 and JR-460).
VARIANT 93 93 G -> E (in strain: JR-50).
VARIANT 110 110 K -> R (in strain: GB-115, JR-50, JR-106,
JR-126, JR-142, JR-198, JR-341 and JR-
382).
VARIANT 154 155 IS -> RG (in strain: JR-32).
VARIANT 155 155 S -> T (in strain: JR-126).
VARIANT 170 170 D -> N (in strain: GB-4, GB-139 and JR-
38).
VARIANT 171 171 L -> F (in strain: JR-106).
VARIANT 193 193 S -> R (in strain: JR-126).
VARIANT 211 211 G -> A (in strain: JR-126).
VARIANT 225 225 L -> V (in strain: GB-4, GB-115 and JR-
142).
VARIANT 248 248 G -> L (in strain: JR-38 and JR-382).
VARIANT 285 285 R -> G (in strain: GB-115).
VARIANT 291 291 A -> S (in strain: GB-4).
VARIANT 313 313 S -> T (in strain: GB-329, GB-336, JR-32
and JR-460).
VARIANT 317 317 V -> I (in strain: GB-329, GB-336, JR-32
and JR-460).
VARIANT 326 326 A -> S (in strain: GB-329 and JR-32).
VARIANT 327 327 Q -> K (in strain: GB-336, JR-126 and JR-
460).
VARIANT 334 334 Y -> C (in strain: JR-106).
VARIANT 386 386 D -> Y (in strain: JR-341).
VARIANT 444 444 D -> E (in strain: GB-336).
VARIANT 474 474 I -> M (in strain: GB-336, JR-32, JR-50,
JR-106 and JR-382).
VARIANT 488 488 E -> K (in strain: GB-329).
VARIANT 491 491 I -> V (in strain: GB-8).
VARIANT 514 514 T -> A (in strain: GB-336, JR-32, JR-50,
JR-106 and JR-126).
VARIANT 523 523 S -> R (in strain: GB-139, GB-329, JR-142
and JR-460).
VARIANT 532 532 T -> S (in strain: JR-341).
VARIANT 533 533 R -> Q (in strain: JR-50).
CONFLICT 92 92 Q -> R (in Ref. 1; AAA28515).
{ECO:0000305}.
SEQUENCE 545 AA; 60652 MW; 3C329272BDBE5CCE CRC64;
MYCAKLILLL GCFWISSSAS DPADPLLVDL PNGKLRGRDN GNYYSYESLP YAEPPVGDLR
FEAPQPYKQQ WTDTFDATQP PVLCMQWDQF IQGDDKLAGN EDCLTVSVYK PKNSSRNSFP
VVAQIHGGAF MFGGASQNGH ENFMREGNLI LVKISYRLGP LGFVSTGDAD LSGNFGLKDQ
RLALLWIKQN IASFGGEPEN ILVIGHSAGG GSVHLQVLRE DFSKLAKAAI SFSGNALDPW
VVQQGGRGRA FELGRIVGCG QASDSVTLKK CLKSKPASEI VSAVRNFLVF AYVPFTPFGP
VVESPDAPEA FISQHPVDII KSGKFAQVPW AVTYTTEDGG YNAALLLEKQ ASSGRELIVD
LNDRWFDWAP YLLFYRDSMT TIKDMDDYSR KLRQEYLGDR RFSVESYWDL QRLFTDVLFK
NSTEISLDLH RKHGKSPVYA FVYDNPANTG IGQGLAKRTD INFGTVHGDD YFLIFENIVR
EPQLRSDEEI ISRNFLKMLN DFVLSENGTL AFGTCVFQDN VGSSKLQLLS ITRNGCENLE
LESFP


Related products :

Catalog number Product name Quantity
EIAAB13343 Carboxyesterase ES-1,E1,Es2,Esterase-2,ES-THET,Liver carboxylesterase 1,Neutral retinyl ester hydrolase,NREH,Rat,Rattus norvegicus,REH,Retinyl ester hydrolase
EIAAB06895 Carboxyesterase ES-10,Carboxylesterase 3,Ces3,ES-HVEL,FAEE synthase,Fatty acid ethyl ester synthase,Liver carboxylesterase 10,pI 6.1 esterase,Rat,Rattus norvegicus
EIAAB13337 ACAT,Acyl-coenzyme A cholesterol acyltransferase,Brain carboxylesterase hBr1,CES1,CES2,Cocaine carboxylesterase,Egasyn,HMSE,Homo sapiens,Human,Liver carboxylesterase 1,Monocyte_macrophage serine ester
EIAAB06894 Carboxylesterase 3,Ces1,Ces3,FAEE synthase,Fatty acid ethyl ester synthase,Mouse,Mus musculus,TGH,Triacylglycerol hydrolase
EIAAB13357 Es10,Esd,Esterase 10,Esterase D,FGH,Mouse,Mus musculus,S-formylglutathione hydrolase,Sid 478,Sid478
enz-447 Recombinant Human Esterase D,S-Formylglutathione Hydrolase Esterase-D 50
enz-447 Recombinant Human Esterase D,S-Formylglutathione Hydrolase Esterase-D 10
enz-447 Recombinant Human Esterase D,S-Formylglutathione Hydrolase Esterase-D 1mg
201-20-1029 CES1{carboxylesterase 1 (monocyte_macrophage serine esterase 1)}rabbit.pAb 0.1ml
CES3 CES1 Gene carboxylesterase 1 (monocyte_macrophage serine esterase 1)
orb90090 Human Esterase D,S-Formylglutathione Hydrolase protein Esterase-D Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E.coli is a single, non-glycosylated, polypeptide chain c 10
18-783-77594 RABBIT ANTI PORCINE ESTERASE - EC 3.1.1.1; Non-specific carboxylesterase Polyclonal 1 ml
EIAAB13347 Es31,ES-male,Esterase-31,Liver carboxylesterase 31,Mouse,Mus musculus
GWB-9FBB60 Anti- CES1 (carboxylesterase 1 (monocyte_macrophage serine esterase 1)) Antibody
EIAAB13344 Egasyn,Es22,Es-22,Esterase-22,Liver carboxylesterase 22,Mouse,Mus musculus
EIAAB13342 Carboxylesterase 2,CE-2,CES2,Cocaine esterase,hCE-2,Homo sapiens,Human,ICE
EIAAB13345 Carboxyesterase ES-3,Ces1,ES-HTEL,Liver carboxylesterase 3,pI 5.5 esterase,Rat,Rattus norvegicus
GWB-9FBB60 Anti- CES1 (carboxylesterase 1 (monocyte macrophage serine esterase 1)) Antibody
CSB-EL005258RA Rat carboxylesterase 1 (monocyte_macrophage serine esterase 1) (CES1) ELISA kit, Species Rat, Sample Type serum, plasma 96T
GWB-6A4D8C Carboxylesterase 1 (monocyte_macrophage Serine Esterase 1) (CES1) Goat anti-Human Polyclonal (Internal) Antibody
GWB-6A4D8C Carboxylesterase 1 (monocyte macrophage Serine Esterase 1) (CES1) Goat anti-Human Polyclonal (Internal) Antibody
EIAAB06893 CES1P1,CES4,Homo sapiens,Human,Inactive carboxylesterase 1 pseudogene 1,PCE-3,Placental carboxylesterase 3,Putative inactive carboxylesterase 4
CSB-EL005258MO Mouse carboxylesterase 1 (monocyte_macrophage serine esterase 1) (CES1) ELISA kit, Species Mouse, Sample Type serum, plasma 96T
CSB-EL005258HU Human carboxylesterase 1 (monocyte_macrophage serine esterase 1) (CES1) ELISA kit, Species Human, Sample Type serum, plasma 96T
50741-46-3 Quinoline-3-carboxylic acid ethyl ester Quinoline-3-carboxylic 1g


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur