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Fasciclin 2, isoform G

 X2JAF4_DROME            Unreviewed;       885 AA.
X2JAF4;
11-JUN-2014, integrated into UniProtKB/TrEMBL.
11-JUN-2014, sequence version 1.
22-NOV-2017, entry version 34.
SubName: Full=Fasciclin 2, isoform G {ECO:0000313|EMBL:AHN59325.1};
Name=Fas2 {ECO:0000313|EMBL:AHN59325.1,
ECO:0000313|FlyBase:FBgn0000635};
Synonyms=1D4 {ECO:0000313|EMBL:AHN59325.1},
Ab 1D4 {ECO:0000313|EMBL:AHN59325.1},
anon-EST:Liang-1.60 {ECO:0000313|EMBL:AHN59325.1},
clone 1.60 {ECO:0000313|EMBL:AHN59325.1},
CT12301 {ECO:0000313|EMBL:AHN59325.1},
Dmel\CG3665 {ECO:0000313|EMBL:AHN59325.1},
EG:EG0007.3 {ECO:0000313|EMBL:AHN59325.1},
Fas {ECO:0000313|EMBL:AHN59325.1},
FAS 11 {ECO:0000313|EMBL:AHN59325.1},
Fas 2 {ECO:0000313|EMBL:AHN59325.1},
FAS II {ECO:0000313|EMBL:AHN59325.1},
Fas II {ECO:0000313|EMBL:AHN59325.1},
fas II {ECO:0000313|EMBL:AHN59325.1},
Fas-II {ECO:0000313|EMBL:AHN59325.1},
fas-II {ECO:0000313|EMBL:AHN59325.1},
FAS2 {ECO:0000313|EMBL:AHN59325.1},
fas2 {ECO:0000313|EMBL:AHN59325.1},
fasciclin II {ECO:0000313|EMBL:AHN59325.1},
FascII {ECO:0000313|EMBL:AHN59325.1},
FASII {ECO:0000313|EMBL:AHN59325.1},
FasII {ECO:0000313|EMBL:AHN59325.1},
Fasii {ECO:0000313|EMBL:AHN59325.1},
fasII {ECO:0000313|EMBL:AHN59325.1},
l(1)G0032 {ECO:0000313|EMBL:AHN59325.1},
l(1)G0048 {ECO:0000313|EMBL:AHN59325.1},
l(1)G0081 {ECO:0000313|EMBL:AHN59325.1},
l(1)G0293 {ECO:0000313|EMBL:AHN59325.1},
l(1)G0336 {ECO:0000313|EMBL:AHN59325.1},
mAb 1D4 {ECO:0000313|EMBL:AHN59325.1},
MAB1D4 {ECO:0000313|EMBL:AHN59325.1},
mAB1D4 {ECO:0000313|EMBL:AHN59325.1},
mAb1D4 {ECO:0000313|EMBL:AHN59325.1};
ORFNames=CG3665 {ECO:0000313|EMBL:AHN59325.1,
ECO:0000313|FlyBase:FBgn0000635},
Dmel_CG3665 {ECO:0000313|EMBL:AHN59325.1};
Drosophila melanogaster (Fruit fly).
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
Ephydroidea; Drosophilidae; Drosophila; Sophophora.
NCBI_TaxID=7227 {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803};
[1] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=10731132; DOI=10.1126/science.287.5461.2185;
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X.,
Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D.,
Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L.,
Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D.,
Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M.,
Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S.,
Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P.,
Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I.,
Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P.,
de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M.,
Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P.,
Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W.,
Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K.,
Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J.,
Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C.,
Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A.,
Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z.,
Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X.,
Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D.,
Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A.,
Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L.,
Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M.,
Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G.,
Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H.,
Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.,
Spier E., Spradling A.C., Stapleton M., Strong R., Sun E.,
Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X.,
Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J.,
Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J.,
Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L.,
Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O.,
Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.;
"The genome sequence of Drosophila melanogaster.";
Science 287:2185-2195(2000).
[2] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537568;
Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A.,
Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A.,
George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R.,
Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J.,
Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C.,
Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.;
"Finishing a whole-genome shotgun: release 3 of the Drosophila
melanogaster euchromatic genome sequence.";
Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002).
[3] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
GENOME REANNOTATION.
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P.,
Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A.,
Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q.,
Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M.,
Lewis S.E.;
"Annotation of the Drosophila melanogaster euchromatic genome: a
systematic review.";
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
[4] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537573;
Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R.,
Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M.,
Ashburner M., Celniker S.E.;
"The transposable elements of the Drosophila melanogaster euchromatin:
a genomics perspective.";
Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002).
[5] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=12537574;
Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A.,
Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G.,
Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M.,
Karpen G.H.;
"Heterochromatic sequences in a Drosophila whole-genome shotgun
assembly.";
Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002).
[6] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=16110336; DOI=10.1371/journal.pcbi.0010022;
Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D.,
Ashburner M., Anxolabehere D.;
"Combined evidence annotation of transposable elements in genome
sequences.";
PLoS Comput. Biol. 1:166-175(2005).
[7] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=17569856; DOI=10.1126/science.1139815;
Smith C.D., Shu S., Mungall C.J., Karpen G.H.;
"The Release 5.1 annotation of Drosophila melanogaster
heterochromatin.";
Science 316:1586-1591(2007).
[8] {ECO:0000313|EMBL:AHN59325.1, ECO:0000313|Proteomes:UP000000803}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803};
PubMed=17569867; DOI=10.1126/science.1139816;
Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M.,
Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A.,
Dimitri P., Karpen G.H., Celniker S.E.;
"Sequence finishing and mapping of Drosophila melanogaster
heterochromatin.";
Science 316:1625-1628(2007).
-----------------------------------------------------------------------
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EMBL; AE014298; AHN59325.1; -; Genomic_DNA.
RefSeq; NP_001284854.1; NM_001297925.1.
UniGene; Dm.1687; -.
ProteinModelPortal; X2JAF4; -.
PaxDb; X2JAF4; -.
EnsemblMetazoa; FBtr0343523; FBpp0310127; FBgn0000635.
GeneID; 31364; -.
CTD; 31364; -.
FlyBase; FBgn0000635; Fas2.
eggNOG; ENOG410IQJI; Eukaryota.
eggNOG; ENOG410XTGB; LUCA.
GeneTree; ENSGT00860000133697; -.
OMA; VDWLYNG; -.
OrthoDB; EOG091G02K3; -.
ChiTaRS; Fas2; fly.
GenomeRNAi; 31364; -.
Proteomes; UP000000803; Chromosome X.
Bgee; FBgn0000635; -.
ExpressionAtlas; X2JAF4; differential.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0007155; P:cell adhesion; IEA:InterPro.
CDD; cd00063; FN3; 2.
Gene3D; 2.60.40.10; -; 7.
InterPro; IPR003961; FN3_dom.
InterPro; IPR036116; FN3_sf.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR013098; Ig_I-set.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR009138; Neural_cell_adh.
Pfam; PF00041; fn3; 2.
Pfam; PF07679; I-set; 3.
PRINTS; PR01838; NCAMFAMILY.
SMART; SM00060; FN3; 2.
SMART; SM00409; IG; 5.
SMART; SM00408; IGc2; 5.
SUPFAM; SSF48726; SSF48726; 5.
SUPFAM; SSF49265; SSF49265; 1.
PROSITE; PS50853; FN3; 2.
PROSITE; PS50835; IG_LIKE; 5.
1: Evidence at protein level;
Complete proteome {ECO:0000313|Proteomes:UP000000803};
Membrane {ECO:0000256|SAM:Phobius};
Proteomics identification {ECO:0000213|PeptideAtlas:X2JAF4};
Reference proteome {ECO:0000313|Proteomes:UP000000803};
Repeat {ECO:0000256|SAAS:SAAS00923712};
Signal {ECO:0000256|SAM:SignalP};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
SIGNAL 1 28 {ECO:0000256|SAM:SignalP}.
CHAIN 29 885 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5004951427.
TRANSMEM 752 781 Helical. {ECO:0000256|SAM:Phobius}.
DOMAIN 31 131 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 152 223 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 230 318 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 323 423 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 428 520 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 524 622 Fibronectin type-III.
{ECO:0000259|PROSITE:PS50853}.
DOMAIN 638 738 Fibronectin type-III.
{ECO:0000259|PROSITE:PS50853}.
SEQUENCE 885 AA; 98410 MW; 44FA1AFC8FE16224 CRC64;
MGELPPNSVG VFLALLLCSC SLIELTRAQS PILEIYPKQE VQRKPVGKPL ILTCRPTVPE
PSLVADLQWK DNRNNTILPK PNGRNQPPMY TETLPGESLA LMITSLSVEM GGKYYCTASY
ANTEILEKGV TIKTYVAITW TNAPENQYPT LGQDYVVMCE VKADPNPTID WLRNGDPIRT
TNDKYVVQTN GLLIRNVQES DEGIYTCRAA VIETGELLER TIRVEVFIQP EIISLPTNLE
AVEGKPFAAN CTARGKPVPE ISWIRDATQL NVATADRFQV NPQTGLVTIS SVSQDDYGTY
TCLAKNRAGV VDQKTKLNVL VRPQIYELYN VTGARTKEIA ITCRAKGRPA PAITFRRWGT
QEEYTNGQQD DDPRIILEPN FDEERGESTG TLRISNAERS DDGLYQCIAR NKGADAYKTG
HITVEFAPDF SHMKELPPVF SWEQRKANLS CLAMGIPNAT IEWHWNGRKI KDLYDTNLKI
VGTGPRSDLI VHPVTRQYYS GYKCIATNIH GTAEHDMQLK EARVPDFVSE AKPSQLTATT
MTFDIRGPST ELGLPILAYS VQYKEALNPD WSTAYNRSWS PDSPYIVEGL RPQTEYSFRF
AARNQVGLGN WGVNQQQSTP RRSAPEEPKP LHNPVQHDKE EPVVVSPYSD HFELRWGVPA
DNGEPIDRYQ IKYCPGVKIS GTWTELENSC NTVEVMETTS FEMTQLVGNT YYRIELKAHN
AIGYSSPASI IMKTTRGIDV IQVAERQVFS SAAIVGIAIG GVLLLLFVVD LLCCITVHMG
VMATMCRKAK RSPSEIDDEA KLGSLYGWRF PLPYCSGQLV KEPPPSPLPL PPPVKLGGSP
MSTPLDEKEP LRTPTGSIKQ NSTIEFDGRF VHSRSGEIIG KNSAV


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