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Fel d 7 allergen (Lipocalin 1)

 E5D2Z5_FELCA            Unreviewed;       180 AA.
E5D2Z5;
08-FEB-2011, integrated into UniProtKB/TrEMBL.
08-FEB-2011, sequence version 1.
10-OCT-2018, entry version 59.
SubName: Full=Fel d 7 allergen {ECO:0000313|EMBL:ADK56160.1};
Name=LOC100533977 {ECO:0000313|Ensembl:ENSFCAP00000037326};
Felis catus (Cat) (Felis silvestris catus).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
Felinae; Felis.
NCBI_TaxID=9685 {ECO:0000313|EMBL:ADK56160.1};
[1] {ECO:0000313|Ensembl:ENSFCAP00000037326, ECO:0000313|Proteomes:UP000011712}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000037326,
ECO:0000313|Proteomes:UP000011712};
PubMed=17975172; DOI=10.1101/gr.6380007;
Pontius J.U., Mullikin J.C., Smith D.R., Lindblad-Toh K., Gnerre S.,
Clamp M., Chang J., Stephens R., Neelam B., Volfovsky N.,
Schaffer A.A., Agarwala R., Narfstrom K., Murphy W.J., Giger U.,
Roca A.L., Antunes A., Menotti-Raymond M., Yuhki N.,
Pecon-Slattery J., Johnson W.E., Bourque G., Tesler G., O'Brien S.J.;
"Initial sequence and comparative analysis of the cat genome.";
Genome Res. 17:1675-1689(2007).
[2] {ECO:0000313|EMBL:ADK56160.1}
NUCLEOTIDE SEQUENCE.
TISSUE=Von Ebner gland {ECO:0000313|EMBL:ADK56160.1};
Smith W.-A., Thomas W.R., O'Neill S.;
"Fel d 7, a new and important cat allergen.";
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|Ensembl:ENSFCAP00000037326, ECO:0000313|Proteomes:UP000011712}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000037326,
ECO:0000313|Proteomes:UP000011712};
Hillier L.W., Warren W., Obrien S., Wilson R.K.;
"Sequence assembly of the Felis catus genome version 6.2.";
Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|Ensembl:ENSFCAP00000037326}
IDENTIFICATION.
STRAIN=breed Abyssinian {ECO:0000313|Ensembl:ENSFCAP00000037326};
Ensembl;
Submitted (JAN-2018) to UniProtKB.
-!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
{ECO:0000256|SAAS:SAAS00972821}.
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EMBL; AANG04001725; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; GU108332; ADK56160.1; -; mRNA.
RefSeq; NP_001191706.1; NM_001204777.1.
STRING; 9685.ENSFCAP00000005327; -.
Allergome; 8431; Fel d 7.
Allergome; 8432; Fel d 7.0101.
Ensembl; ENSFCAT00000042335; ENSFCAP00000037326; ENSFCAG00000005739.
GeneID; 100533977; -.
KEGG; fca:100533977; -.
eggNOG; ENOG410J1KM; Eukaryota.
eggNOG; ENOG4111BH9; LUCA.
GeneTree; ENSGT00440000033563; -.
OMA; SGKWYLK; -.
OrthoDB; EOG091G0PIH; -.
TreeFam; TF338197; -.
Proteomes; UP000011712; Chromosome D4.
Bgee; ENSFCAG00000005739; Expressed in 3 organ(s), highest expression level in adult mammalian kidney.
GO; GO:0036094; F:small molecule binding; IEA:InterPro.
Gene3D; 2.40.128.20; -; 1.
InterPro; IPR012674; Calycin.
InterPro; IPR002345; Lipocalin.
InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
InterPro; IPR002450; von_Ebner_gland.
PANTHER; PTHR11430; PTHR11430; 1.
Pfam; PF00061; Lipocalin; 1.
PRINTS; PR01175; VNEBNERGLAND.
SUPFAM; SSF50814; SSF50814; 1.
2: Evidence at transcript level;
Complete proteome {ECO:0000313|Proteomes:UP000011712};
Reference proteome {ECO:0000313|Proteomes:UP000011712};
Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1 18 {ECO:0000256|SAM:SignalP}.
CHAIN 19 180 {ECO:0000256|SAM:SignalP}.
/FTId=PRO_5014088806.
DOMAIN 32 163 Lipocln_cytosolic_FA-bd_dom.
{ECO:0000259|Pfam:PF00061}.
SEQUENCE 180 AA; 20185 MW; CD13ACE2BF943F56 CRC64;
MKALLLAVGL SLITVLQAQD PPASGEDTMA MSGKWYLKAM ITDRETSWKK PELVTPMTLT
VLEGGNLKAE TTLLTNGQCK EVELILEKTS EPKKYTTYGG KRVVYIEPTE VKDHYIFYCE
GEMQGEQARM AKLVGRDPES NEEALENFRE FLRAKGFNQE IFSPKQSDTC PPGTDQEPEV


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