Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) [Cleaved into: Ferritin heavy chain, N-terminally processed]

 FRIH_CANLF              Reviewed;         183 AA.
Q95MP7; Q53VC0;
26-APR-2005, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 3.
28-FEB-2018, entry version 102.
RecName: Full=Ferritin heavy chain;
Short=Ferritin H subunit;
EC=1.16.3.1;
Contains:
RecName: Full=Ferritin heavy chain, N-terminally processed;
Name=FTH1; Synonyms=FTH;
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
Jeoung D., Jung D., Kim H.;
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver, and Spleen;
PubMed=16040348; DOI=10.1080/10425170400024359;
Orino K., Miura T., Muto S., Watanabe K.;
"Sequence analysis of canine and equine ferritin H and L subunit
cDNAs.";
DNA Seq. 16:58-64(2005).
-!- FUNCTION: Stores iron in a soluble, non-toxic, readily available
form. Important for iron homeostasis. Has ferroxidase activity.
Iron is taken up in the ferrous form and deposited as ferric
hydroxides after oxidation. Also plays a role in delivery of iron
to cells. Mediates iron uptake in capsule cells of the developing
kidney (By similarity). {ECO:0000250}.
-!- CATALYTIC ACTIVITY: 4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.
-!- SUBUNIT: Oligomer of 24 subunits. There are two types of subunits:
L (light) chain and H (heavy) chain. The major chain can be light
or heavy, depending on the species and tissue type. The functional
molecule forms a roughly spherical shell with a diameter of 12 nm
and contains a central cavity into which the insoluble mineral
iron core is deposited.
-!- SIMILARITY: Belongs to the ferritin family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
EMBL; AF285177; AAK82992.1; -; mRNA.
EMBL; AB175610; BAD96175.1; -; mRNA.
EMBL; AB175611; BAD96176.1; -; mRNA.
RefSeq; NP_001003080.1; NM_001003080.1.
RefSeq; NP_001180585.1; NM_001193656.1.
UniGene; Cfa.38608; -.
UniGene; Cfa.47833; -.
ProteinModelPortal; Q95MP7; -.
SMR; Q95MP7; -.
STRING; 9615.ENSCAFP00000033829; -.
PaxDb; Q95MP7; -.
PRIDE; Q95MP7; -.
Ensembl; ENSCAFT00000025200; ENSCAFP00000023396; ENSCAFG00000015901.
Ensembl; ENSCAFT00000038151; ENSCAFP00000033829; ENSCAFG00000030465.
GeneID; 100499480; -.
GeneID; 403631; -.
KEGG; cfa:100499480; -.
KEGG; cfa:403631; -.
CTD; 2495; -.
eggNOG; KOG2332; Eukaryota.
eggNOG; COG1528; LUCA.
GeneTree; ENSGT00760000119129; -.
HOGENOM; HOG000223383; -.
HOVERGEN; HBG000410; -.
InParanoid; Q95MP7; -.
KO; K00522; -.
OMA; QALHNFA; -.
OrthoDB; EOG091G0J20; -.
TreeFam; TF313885; -.
Proteomes; UP000002254; Chromosome 11.
Proteomes; UP000002254; Chromosome 18.
Bgee; ENSCAFG00000015901; -.
GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
GO; GO:0004322; F:ferroxidase activity; IEA:UniProtKB-EC.
GO; GO:0005506; F:iron ion binding; IBA:GO_Central.
GO; GO:0006955; P:immune response; ISS:UniProtKB.
GO; GO:0006880; P:intracellular sequestering of iron ion; IBA:GO_Central.
GO; GO:0006826; P:iron ion transport; IEA:InterPro.
GO; GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.
Gene3D; 1.20.1260.10; -; 1.
InterPro; IPR001519; Ferritin.
InterPro; IPR012347; Ferritin-like.
InterPro; IPR009040; Ferritin-like_diiron.
InterPro; IPR009078; Ferritin-like_SF.
InterPro; IPR014034; Ferritin_CS.
InterPro; IPR008331; Ferritin_DPS_dom.
PANTHER; PTHR11431; PTHR11431; 1.
Pfam; PF00210; Ferritin; 1.
SUPFAM; SSF47240; SSF47240; 1.
PROSITE; PS00540; FERRITIN_1; 1.
PROSITE; PS00204; FERRITIN_2; 1.
PROSITE; PS50905; FERRITIN_LIKE; 1.
2: Evidence at transcript level;
Acetylation; Complete proteome; Iron; Iron storage; Metal-binding;
Oxidoreductase; Phosphoprotein; Reference proteome.
CHAIN 1 183 Ferritin heavy chain.
/FTId=PRO_0000201046.
INIT_MET 1 1 Removed; alternate.
{ECO:0000250|UniProtKB:P02794}.
CHAIN 2 183 Ferritin heavy chain, N-terminally
processed.
/FTId=PRO_0000424469.
DOMAIN 11 160 Ferritin-like diiron.
{ECO:0000255|PROSITE-ProRule:PRU00085}.
METAL 28 28 Iron 1. {ECO:0000255|PROSITE-
ProRule:PRU00085}.
METAL 63 63 Iron 1. {ECO:0000255|PROSITE-
ProRule:PRU00085}.
METAL 63 63 Iron 2. {ECO:0000255|PROSITE-
ProRule:PRU00085}.
METAL 66 66 Iron 1. {ECO:0000255|PROSITE-
ProRule:PRU00085}.
METAL 108 108 Iron 2. {ECO:0000255|PROSITE-
ProRule:PRU00085}.
METAL 142 142 Iron 2. {ECO:0000255|PROSITE-
ProRule:PRU00085}.
MOD_RES 1 1 N-acetylmethionine.
{ECO:0000250|UniProtKB:P02794}.
MOD_RES 2 2 N-acetylthreonine; in Ferritin heavy
chain, N-terminally processed.
{ECO:0000250|UniProtKB:P02794}.
MOD_RES 179 179 Phosphoserine.
{ECO:0000250|UniProtKB:P02794}.
MOD_RES 183 183 Phosphoserine.
{ECO:0000250|UniProtKB:P02794}.
SEQUENCE 183 AA; 21308 MW; 9D22750A1AC4BE72 CRC64;
MTTASPSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS
HEEREHAEKL MKLQNQRGGR IFLQDIKKPD RDDWENGLNA MECALHLEKS VNQSLLELHK
LATDKNDPHL CDFIETHYLN EQVKSIKELG DHVTNLRKMG APESGMAEYL FDKHTLGNSD
NES


Related products :

Catalog number Product name Quantity
E0518p ELISA Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,Pig,Sus scrofa 96T
U0518p CLIA Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,Pig,Sus scrofa 96T
E0518p ELISA kit Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,Pig,Sus scrofa 96T
E0518b ELISA Bos taurus,Bovine,Ferritin H subunit,Ferritin heavy chain,FTH,FTH1 96T
E0518m ELISA kit Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,Mouse,Mus musculus 96T
U0518r CLIA Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,Rat,Rattus norvegicus 96T
E0518b ELISA kit Bos taurus,Bovine,Ferritin H subunit,Ferritin heavy chain,FTH,FTH1 96T
U0518m CLIA Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,Mouse,Mus musculus 96T
E0518m ELISA Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,Mouse,Mus musculus 96T
E0518r ELISA Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,Rat,Rattus norvegicus 96T
E0518r ELISA kit Ferritin H subunit,Ferritin heavy chain,Fth,Fth1,Rat,Rattus norvegicus 96T
U0518b CLIA Bos taurus,Bovine,Ferritin H subunit,Ferritin heavy chain,FTH,FTH1 96T
15-288-20077F Ferritin heavy chain - EC 1.16.3.1; Ferritin H subunit; Proliferation-inducing gene 15 protein Polyclonal 0.05 mg
U0518Rb CLIA Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,Oryctolagus cuniculus,Rabbit 96T
15-288-20077F Ferritin heavy chain - EC 1.16.3.1; Ferritin H subunit; Proliferation-inducing gene 15 protein Polyclonal 0.1 mg
E0518Rb ELISA Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,Oryctolagus cuniculus,Rabbit 96T
E0518Rb ELISA kit Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,Oryctolagus cuniculus,Rabbit 96T
E0518h ELISA Cell proliferation-inducing gene 15 protein,Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,FTHL6,Homo sapiens,Human,OK_SW-cl.84,PIG15 96T
E0518h ELISA kit Cell proliferation-inducing gene 15 protein,Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,FTHL6,Homo sapiens,Human,OK_SW-cl.84,PIG15 96T
U0518h CLIA Cell proliferation-inducing gene 15 protein,Ferritin H subunit,Ferritin heavy chain,FTH,FTH1,FTHL6,Homo sapiens,Human,OK_SW-cl.84,PIG15 96T
pro-658 Recombinant Human Ferritin Heavy Chain Ferritin Heavy 25
pro-658 Recombinant Human Ferritin Heavy Chain Ferritin Heavy 5
pro-658 Recombinant Human Ferritin Heavy Chain Ferritin Heavy 1mg
U0518c CLIA Chicken,Ferritin H subunit,Ferritin heavy chain,FTH,Gallus gallus 96T
E0518c ELISA kit Chicken,Ferritin H subunit,Ferritin heavy chain,FTH,Gallus gallus 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur