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Ferrous iron permease EfeU (Fe(2 ) ion permease EfeU) (Ferrous iron uptake protein)

 EFEU_YERPA              Reviewed;         282 AA.
Q1C8M3;
06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
11-JUL-2006, sequence version 1.
07-NOV-2018, entry version 62.
RecName: Full=Ferrous iron permease EfeU;
AltName: Full=Fe(2+) ion permease EfeU;
AltName: Full=Ferrous iron uptake protein;
Name=efeU; OrderedLocusNames=YPA_1232;
Yersinia pestis bv. Antiqua (strain Antiqua).
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
Yersiniaceae; Yersinia.
NCBI_TaxID=360102;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Antiqua;
PubMed=16740952; DOI=10.1128/JB.00124-06;
Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
"Complete genome sequence of Yersinia pestis strains Antiqua and
Nepal516: evidence of gene reduction in an emerging pathogen.";
J. Bacteriol. 188:4453-4463(2006).
-!- FUNCTION: Uptake of Fe(2+) ions across the membrane.
{ECO:0000250}.
-!- SUBUNIT: Part of a ferrous iron transporter composed of EfeU, EfeO
and EfeB. {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-
pass membrane protein {ECO:0000250}.
-!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT)
(TC 9.A.10.1) family. {ECO:0000305}.
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EMBL; CP000308; ABG13199.1; -; Genomic_DNA.
RefSeq; WP_002211165.1; NZ_CP009906.1.
ProteinModelPortal; Q1C8M3; -.
EnsemblBacteria; ABG13199; ABG13199; YPA_1232.
KEGG; ypa:YPA_1232; -.
HOGENOM; HOG000236918; -.
KO; K07243; -.
OMA; WMLIWMT; -.
Proteomes; UP000001971; Chromosome.
GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
InterPro; IPR004923; FTR1/Fip1/EfeU.
PANTHER; PTHR31632; PTHR31632; 1.
Pfam; PF03239; FTR1; 1.
3: Inferred from homology;
Cell inner membrane; Cell membrane; Complete proteome; Ion transport;
Iron; Iron transport; Membrane; Transmembrane; Transmembrane helix;
Transport.
CHAIN 1 282 Ferrous iron permease EfeU.
/FTId=PRO_0000277550.
TOPO_DOM 1 1 Periplasmic. {ECO:0000255}.
TRANSMEM 2 22 Helical. {ECO:0000255}.
TOPO_DOM 23 35 Cytoplasmic. {ECO:0000255}.
TRANSMEM 36 56 Helical. {ECO:0000255}.
TOPO_DOM 57 69 Periplasmic. {ECO:0000255}.
TRANSMEM 70 90 Helical. {ECO:0000255}.
TOPO_DOM 91 118 Cytoplasmic. {ECO:0000255}.
TRANSMEM 119 139 Helical. {ECO:0000255}.
TOPO_DOM 140 147 Periplasmic. {ECO:0000255}.
TRANSMEM 148 168 Helical. {ECO:0000255}.
TOPO_DOM 169 179 Cytoplasmic. {ECO:0000255}.
TRANSMEM 180 200 Helical. {ECO:0000255}.
TOPO_DOM 201 244 Periplasmic. {ECO:0000255}.
TRANSMEM 245 265 Helical. {ECO:0000255}.
TOPO_DOM 266 282 Cytoplasmic. {ECO:0000255}.
SEQUENCE 282 AA; 30688 MW; C6D394DB1BD68055 CRC64;
MFVPFLIMFR EGLEAALIVS LIASYLKRTQ RGQWMGAVWV GVVVAAVLCL AIGIFINETT
GEFPQKQQEL FEGIIAVVAV CILTYMVFWM RKVSKSVKVH LEGAIDNALN SGRGQGWALV
AMVFFAVARE GLESVFFLLA AFQQDVGIGA PIGAILGLVC AILVGMAIYW GGVKLHLAKF
FKWTSLFILF VAAGLAAGAI RAFHEAGLWN HFQDIAFDLT DVLSTHSLLG TFLEGMFGYQ
EAPTVSEVSV YFIYLIPALI LFFLPPRSTA GSAIAAARKI NP


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