Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Gastrin/cholecystokinin type B receptor (CCK-B receptor) (CCK-BR) (Cholecystokinin-2 receptor) (CCK2-R)

 GASR_CANLF              Reviewed;         453 AA.
P30552; O46376;
01-APR-1993, integrated into UniProtKB/Swiss-Prot.
01-APR-1993, sequence version 1.
28-MAR-2018, entry version 108.
RecName: Full=Gastrin/cholecystokinin type B receptor;
Short=CCK-B receptor;
Short=CCK-BR;
AltName: Full=Cholecystokinin-2 receptor;
Short=CCK2-R;
Name=CCKBR;
Canis lupus familiaris (Dog) (Canis familiaris).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;
Canis.
NCBI_TaxID=9615;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Gastric parietal cell;
PubMed=1373504; DOI=10.1073/pnas.89.8.3605;
Kopin A.S., Lee Y.-M., McBride E.W., Miller L.J., Lu M., Lin H.Y.,
Kolakowski L.F. Jr., Beinborn M.;
"Expression cloning and characterization of the canine parietal cell
gastrin receptor.";
Proc. Natl. Acad. Sci. U.S.A. 89:3605-3609(1992).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Song I., Blandizzi C., Brown D.R., Kang D.H., Todisco A., Delvalle J.,
del Tacca M., Owyang C., Yamada T.;
"Molecular cloning and structural analysis of the canine gastrin/CCK-B
receptor gene.";
Submitted (DEC-1997) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Receptor for gastrin and cholecystokinin. The CCK-B
receptors occur throughout the central nervous system where they
modulate anxiety, analgesia, arousal, and neuroleptic activity.
This receptor mediates its action by association with G proteins
that activate a phosphatidylinositol-calcium second messenger
system.
-!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
-!- TISSUE SPECIFICITY: Parietal cells, pancreas, brain and various
neoplastic tissues.
-!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
{ECO:0000255|PROSITE-ProRule:PRU00521}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; M87834; AAA30847.1; -; mRNA.
EMBL; AD001537; AAB87706.1; -; Genomic_DNA.
PIR; S32817; S32817.
RefSeq; NP_001013868.1; NM_001013846.1.
UniGene; Cfa.23476; -.
ProteinModelPortal; P30552; -.
BindingDB; P30552; -.
ChEMBL; CHEMBL5595; -.
KEGG; cfa:485333; -.
HOVERGEN; HBG036927; -.
InParanoid; P30552; -.
KO; K04195; -.
PRO; PR:P30552; -.
Proteomes; UP000002254; Unplaced.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO; GO:0015054; F:gastrin receptor activity; ISS:UniProtKB.
GO; GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.
GO; GO:0007204; P:positive regulation of cytosolic calcium ion concentration; ISS:UniProtKB.
InterPro; IPR009126; Cholcskin_rcpt.
InterPro; IPR000314; Gastrin_rcpt.
InterPro; IPR000276; GPCR_Rhodpsn.
InterPro; IPR017452; GPCR_Rhodpsn_7TM.
Pfam; PF00001; 7tm_1; 1.
PRINTS; PR01822; CCYSTOKININR.
PRINTS; PR00527; GASTRINR.
PRINTS; PR00237; GPCRRHODOPSN.
PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
2: Evidence at transcript level;
Cell membrane; Complete proteome; Disulfide bond;
G-protein coupled receptor; Glycoprotein; Lipoprotein; Membrane;
Palmitate; Receptor; Reference proteome; Transducer; Transmembrane;
Transmembrane helix.
CHAIN 1 453 Gastrin/cholecystokinin type B receptor.
/FTId=PRO_0000069473.
TOPO_DOM 1 57 Extracellular. {ECO:0000255}.
TRANSMEM 58 79 Helical; Name=1. {ECO:0000255}.
TOPO_DOM 80 87 Cytoplasmic. {ECO:0000255}.
TRANSMEM 88 109 Helical; Name=2. {ECO:0000255}.
TOPO_DOM 110 131 Extracellular. {ECO:0000255}.
TRANSMEM 132 150 Helical; Name=3. {ECO:0000255}.
TOPO_DOM 151 170 Cytoplasmic. {ECO:0000255}.
TRANSMEM 171 189 Helical; Name=4. {ECO:0000255}.
TOPO_DOM 190 220 Extracellular. {ECO:0000255}.
TRANSMEM 221 243 Helical; Name=5. {ECO:0000255}.
TOPO_DOM 244 339 Cytoplasmic. {ECO:0000255}.
TRANSMEM 340 361 Helical; Name=6. {ECO:0000255}.
TOPO_DOM 362 379 Extracellular. {ECO:0000255}.
TRANSMEM 380 400 Helical; Name=7. {ECO:0000255}.
TOPO_DOM 401 453 Cytoplasmic. {ECO:0000255}.
LIPID 414 414 S-palmitoyl cysteine. {ECO:0000250}.
CARBOHYD 7 7 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 30 30 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 36 36 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 127 206 {ECO:0000255|PROSITE-ProRule:PRU00521}.
SEQUENCE 453 AA; 48519 MW; 0FAEB7B994B44E1F CRC64;
MELLKLNRSA QGSGAGPGAS LCRAGGALLN SSGAGNLSCE PPRLRGAGTR ELELAIRVTL
YAVIFLMSVG GNVLIIVVLG LSRRLRTVTN AFLLSLAVSD LLLAVACMPF TLLPNLMGTF
IFGTVVCKAV SYLMGVSVSV STLSLVAIAL ERYSAICRPL QARVWQTRSH AARVIIATWM
LSGLLMVPYP VYTAVQPAGG ARALQCVHRW PSARVRQTWS VLLLLLLFFV PGVVMAVAYG
LISRELYLGL RFDEDSDSES RVRSQGGLRG GAGPGPAPPN GSCRPEGGLA GEDGDGCYVQ
LPRSRQTLEL SALTAPTPGP GGGPRPYQAK LLAKKRVVRM LLVIVVLFFL CWLPLYSANT
WRAFDSSGAH RALSGAPISF IHLLSYASAC VNPLVYCFMH RRFRQACLET CARCCPRPPR
ARPRPLPDED PPTPSIASLS RLSYTTISTL GPG


Related products :

Catalog number Product name Quantity
E1051b ELISA Bos taurus,Bovine,CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor 96T
E1051m ELISA kit CCK2-R,CCK-B receptor,Cckbr,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Mouse,Mus musculus 96T
U1051b CLIA Bos taurus,Bovine,CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor 96T
U1051m CLIA CCK2-R,CCK-B receptor,Cckbr,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Mouse,Mus musculus 96T
E1051r ELISA kit CCK2-R,CCK-B receptor,Cckbr,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Rat,Rattus norvegicus 96T
E1051r ELISA CCK2-R,CCK-B receptor,Cckbr,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Rat,Rattus norvegicus 96T
U1051r CLIA CCK2-R,CCK-B receptor,Cckbr,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Rat,Rattus norvegicus 96T
E1051b ELISA kit Bos taurus,Bovine,CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor 96T
E1051m ELISA CCK2-R,CCK-B receptor,Cckbr,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Mouse,Mus musculus 96T
E1051Rb ELISA CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Oryctolagus cuniculus,Rabbit 96T
E1051Rb ELISA kit CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Oryctolagus cuniculus,Rabbit 96T
U1051Rb CLIA CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Oryctolagus cuniculus,Rabbit 96T
E1051h ELISA kit CCK2-R,CCK-B receptor,CCKBR,CCK-BR,CCKRB,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Homo sapiens,Human 96T
E1051h ELISA CCK2-R,CCK-B receptor,CCKBR,CCK-BR,CCKRB,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Homo sapiens,Human 96T
U1051h CLIA CCK2-R,CCK-B receptor,CCKBR,CCK-BR,CCKRB,Cholecystokinin-2 receptor,Gastrin_cholecystokinin type B receptor,Homo sapiens,Human 96T
EIAAB06107 CCK1-R,CCK-A receptor,CCKAR,CCK-AR,CCKRA,Cholecystokinin receptor type A,Cholecystokinin-1 receptor,Homo sapiens,Human
EIAAB06103 CCK1-R,CCK-A receptor,CCKAR,CCK-AR,Cholecystokinin receptor type A,Cholecystokinin-1 receptor,Oryctolagus cuniculus,Rabbit
EIAAB06105 CCK1-R,CCK-A receptor,Cckar,CCK-AR,Cholecystokinin receptor type A,Cholecystokinin-1 receptor,Mouse,Mus musculus
EIAAB06104 CCK1-R,CCK-A receptor,Cckar,CCK-AR,Cholecystokinin receptor type A,Cholecystokinin-1 receptor,Rat,Rattus norvegicus
U1051c CLIA Canis familiaris,Canis lupus familiaris,CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Dog,Gastrin_cholecystokinin type B receptor 96T
E1051c ELISA Canis familiaris,Canis lupus familiaris,CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Dog,Gastrin_cholecystokinin type B receptor 96T
E1051c ELISA kit Canis familiaris,Canis lupus familiaris,CCK2-R,CCK-B receptor,CCKBR,CCK-BR,Cholecystokinin-2 receptor,Dog,Gastrin_cholecystokinin type B receptor 96T
18-461-10740 Cholecystokinin type A receptor - CCK-A receptor; CCK-AR; Cholecystokinin-1 receptor; CCK1-R Polyclonal 0.05 ml
18-461-10739 Cholecystokinin type A receptor - CCK-A receptor; CCK-AR; Cholecystokinin-1 receptor; CCK1-R Polyclonal 0.05 ml
AE1129AG.1 Cholecystokinin Receptor (CCK-R) antigen: human Cholecystokinin-Receptor Type A (aa 180-195) 100


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur